摘要
WinBUGS软件实现Meta分析的关键在于构建贝叶斯统计模型,目前有手工编写代码和构建Doodle模型两种方法。手工编写代码具有灵活、方便的特点,但编写语言易错;Doodle模型的构建过程较为繁琐,但不易出错,且有利于加强对手工代码结构的理解。本文简要介绍使用WinBUGS软件行二分类和连续型数据的传统Meta分析、间接比较证据的Meta分析及网状Meta分析和有序变量的Meta分析时Doodle模型的构建。
The key for performing meta-analysis using WinBUGS software is to construct a model of Bayesian statistics. The hand-written code model and Doodle model are two major methods for constructing it. The approach of hand-written code is l exible and convenient, but the language programming is fallibility. The Doodle is complicated, but it is benei t to understand the structure of hand-written code model and prevent error. h is article briel y describes how to construct the Doodle model for binary and continuous data of head to head meta-analysis, indirect comparison and network meta-analysis, and ordinal variables meta-analysis.
引文
1 曾宪涛,冷卫东,郭毅,等.Meta分析系列之一:Meta分析的类型.中国循证心血管医学杂志,2012,4(1):3-5.
2 曾宪涛,Kwong JSW,田国祥,等.Meta分析系列之二:Meta分析的软件.中国循证心血管医学杂志,2012,4(1):89-91.
3 董圣杰,冷卫东,田家祥,等.Meta分析系列之五:贝叶斯Meta分析与WinBUGS软件.中国循证心血管医学杂志,2012,4(5):395-398.
4 罗杰,冷卫东,主编.系统评价/Meta分析理论与实践.第1版.北京:军事医学科学出版社,2013:327-347.
5 曾宪涛,曹世义,孙凤,等.Meta分析系列之六:间接比较及网状Meta分析.中国循证心血管医学杂志,2012,4(5):399-402.
6 Lunn D,Jackson C,h omas A,et al.The BUGS Book:A Practical Introduction to Bayesian Analysis.London:CRC Press/Chapman and Hall,2012.
7 曾宪涛,金晶,向招燕,等.思密达与锡类散比较治疗小儿口腔溃疡的Meta分析.中国循证医学杂志,2012,12(3):326-333.