Feasibility of using marginal liver grafts in living donor liver transplantation
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摘要
Liver transplantation(LT) is one of the most effective treatments for end-stage liver disease caused by related risk factors when liver resection is contraindicated. Additionally,despite the decrease in the prevalence of hepatitis B virus(HBV) over the past two decades,the absolute number of HBs Ag-positive people has increased,leading to an increase in HBV-related liver cirrhosis and hepatocellular carcinoma. Consequently,a large demand exists for LT. While the wait time for patients on the donor list is,to some degree,shorter due to the development of living donor liver transplantation(LDLT),there is still a shortage of liver grafts. Furthermore,recipients often suffer from emergent conditions,such as liver dysfunction or even hepatic encephalopathy,which can lead to a limited choice in grafts. To expand the pool of available liver grafts,one option is the use of organs that were previously considered "unusable" by many,which are often labeled "marginal" organs. Many previous studies have reported on the possibilities of using marginal grafts in orthotopic LT; however,there is still a lack of discussion on this topic,especially regarding the feasibility of using marginal grafts in LDLT. Therefore,the present review aimed to summarize the feasibility of using marginal liver grafts for LDLT and discuss the possibility of expanding the application of these grafts.
Liver transplantation(LT) is one of the most effective treatments for end-stage liver disease caused by related risk factors when liver resection is contraindicated. Additionally,despite the decrease in the prevalence of hepatitis B virus(HBV) over the past two decades,the absolute number of HBs Ag-positive people has increased,leading to an increase in HBV-related liver cirrhosis and hepatocellular carcinoma. Consequently,a large demand exists for LT. While the wait time for patients on the donor list is,to some degree,shorter due to the development of living donor liver transplantation(LDLT),there is still a shortage of liver grafts. Furthermore,recipients often suffer from emergent conditions,such as liver dysfunction or even hepatic encephalopathy,which can lead to a limited choice in grafts. To expand the pool of available liver grafts,one option is the use of organs that were previously considered "unusable" by many,which are often labeled "marginal" organs. Many previous studies have reported on the possibilities of using marginal grafts in orthotopic LT; however,there is still a lack of discussion on this topic,especially regarding the feasibility of using marginal grafts in LDLT. Therefore,the present review aimed to summarize the feasibility of using marginal liver grafts for LDLT and discuss the possibility of expanding the application of these grafts.
Liver transplantation(LT) is one of the most effective treatments for end-stage liver disease caused by related risk factors when liver resection is contraindicated. Additionally,despite the decrease in the prevalence of hepatitis B virus(HBV) over the past two decades,the absolute number of HBs Ag-positive people has increased,leading to an increase in HBV-related liver cirrhosis and hepatocellular carcinoma. Consequently,a large demand exists for LT. While the wait time for patients on the donor list is,to some degree,shorter due to the development of living donor liver transplantation(LDLT),there is still a shortage of liver grafts. Furthermore,recipients often suffer from emergent conditions,such as liver dysfunction or even hepatic encephalopathy,which can lead to a limited choice in grafts. To expand the pool of available liver grafts,one option is the use of organs that were previously considered "unusable" by many,which are often labeled "marginal" organs. Many previous studies have reported on the possibilities of using marginal grafts in orthotopic LT; however,there is still a lack of discussion on this topic,especially regarding the feasibility of using marginal grafts in LDLT. Therefore,the present review aimed to summarize the feasibility of using marginal liver grafts for LDLT and discuss the possibility of expanding the application of these grafts.
引文
1 Fisher RA.Living donor liver transplantation:eliminating the wait for death in end-stage liver disease?Nat Rev Gastroenterol Hepatol 2017;14:373-382[PMID:28196987 DOI:10.1038/nrgastro.2017.2]
2 Makuuchi M,Kawasaki S,Noguchi T,Hashikura Y,Matsunami H,Hayashi K,Harada H,Kakazu T,Takayama T,Kawarasaki H.Donor hepatectomy for living related partial liver transplantation.Surgery 1993;113:395-402[PMID:8456395]
3 Makuuchi M,Kawarazaki H,Iwanaka T,Kamada N,Takayama T,Kumon M.Living related liver transplantation.Surg Today 1992;22:297-300[PMID:1392338]
4 Routh D,Sharma S,Naidu CS,Rao PP,Sharma AK,Ranjan P.Comparison of outcomes in ideal donor and extended criteria donor in deceased donor liver transplant:a prospective study.Int J Surg 2014;12:774-777[PMID:24947949 DOI:10.1016/j.ijsu.2014.06.003]
5 Nure E,Lirosi MC,Frongillo F,Bianco G,Silvestrini N,Fiorillo C,Sganga G,Agnes S.Overextended Criteria Donors:Experience of an Italian Transplantation Center.Transplant Proc 2015;47:2102-2105[PMID:26361653 DOI:10.1016/j.transproceed.2014.11.077]
6 Laing RW,Mergental H,Yap C,Kirkham A,Whilku M,Barton D,Curbishley S,Boteon YL,Neil DA,Hübscher SG,Perera MTPR,Muiesan P,Isaac J,Roberts KJ,Cilliers H,Afford SC,Mirza DF.Viability testing and transplantation of marginal livers(VITTAL)using normothermic machine perfusion:study protocol for an open-label,non-randomised,prospective,single-arm trial.BMJ Open 2017;7:e017733[PMID:29183928 DOI:10.1136/bmjopen-2017-017733]
7 Nemes B,Gelley F,Zádori G,Piros L,Perneczky J,Kóbori L,Fehérvári I,G?r?g D.Outcome of liver transplantation based on donor graft quality and recipient status.Transplant Proc 2010;42:2327-2330[PMID:20692473 DOI:10.1016/j.transproceed.2010.05.018]
8 Giretti G,Barbier L,Bucur P,Marques F,Perarnau JM,Ferrandière M,Tellier AC,Kerouredan V,Altieri M,Causse X,Debette-Gratien M,Silvain C,SalaméE.Recipient Selection for Optimal Utilization of Discarded Grafts in Liver Transplantation.Transplantation 2018;102:775-782[PMID:29298235 DOI:10.1097/TP.0000000000002069]
9 Dirican A,Baskiran A,Dogan M,Ates M,Soyer V,Sarici B,Ozdemir F,Polat Y,Yilmaz S.Evaluation of Potential Donors in Living Donor Liver Transplantation.Transplant Proc 2015;47:1315-1318[PMID:26093708 DOI:10.1016/j.transproceed.2015.04.045]
10 Kiuchi T,Kasahara M,Uryuhara K,Inomata Y,Uemoto S,Asonuma K,Egawa H,Fujita S,Hayashi M,Tanaka K.Impact of graft size mismatching on graft prognosis in liver transplantation from living donors.Transplantation 1999;67:321-327[PMID:10075602]
11 Lee DS,Gil WH,Lee HH,Lee KW,Lee SK,Kim SJ,Choi SH,Heo JS,Hyon WS,Kim GS,Paik SW,Koh KC,Joh JW.Factors affecting graft survival after living donor liver transplantation.Transplant Proc 2004;36:2255-2256[PMID:15561210 DOI:10.1016/j.transproceed.2004.08.073]
12 Fan ST,Lo CM,Liu CL,Yong BH,Wong J.Determinants of hospital mortality of adult recipients of right lobe live donor liver transplantation.Ann Surg 2003;238:864-869;discussion 869-870[PMID:14631223 DOI:10.1097/01.sla.0000098618.11382.77]
13 Moon JI,Kwon CH,Joh JW,Jung GO,Choi GS,Park JB,Kim JM,Shin M,Kim SJ,Lee SK.Safety of small-for-size grafts in adult-to-adult living donor liver transplantation using the right lobe.Liver Transpl 2010;16:864-869[PMID:20583075 DOI:10.1002/lt.22094]
14 Lan X,Li B,Wang XF,Peng CJ,Wei YG,Yan LN.[Feasibility of small size graft following living donor liver transplantation].Zhonghua Wai Ke Za Zhi 2009;47:1218-1220[PMID:19781165]
15 Selzner M,Kashfi A,Cattral MS,Selzner N,Greig PD,Lilly L,Mc Gilvray ID,Therapondos G,Adcock LE,Ghanekar A,Levy GA,Renner EL,Grant DR.A graft to body weight ratio less than 0.8 does not exclude adult-to-adult right-lobe living donor liver transplantation.Liver Transpl 2009;15:1776-1782[PMID:19938139 DOI:10.1002/lt.21955]
16 Chen PX,Yan LN,Wang WT.Outcome of patients undergoing right lobe living donor liver transplantation with small-for-size grafts.World J Gastroenterol 2014;20:282-289[PMID:24415883DOI:10.3748/wjg.v20.i1.282]
17 She WH,Chok KS,Fung JY,Chan AC,Lo CM.Outcomes of right-lobe and left-lobe living-donor liver transplantations using small-for-size grafts.World J Gastroenterol 2017;23:4270-4277[PMID:28694667 DOI:10.3748/wjg.v23.i23.4270]
18 Lee SD,Kim SH,Kim YK,Lee SA,Park SJ.Graft-to-recipient weight ratio lower to 0.7%is safe without portal pressure modulation in right-lobe living donor liver transplantation with favorable conditions.Hepatobiliary Pancreat Dis Int 2014;13:18-24[PMID:24463075]
19 Alim A,Erdogan Y,Yuzer Y,Tokat Y,Oezcelik A.Graft-torecipient weight ratio threshold adjusted to the model for end-stage liver disease score for living donor liver transplantation.Liver Transpl 2016;22:1643-1648[PMID:27509534 DOI:10.1002/lt.24523]
20 Lee SG.A complete treatment of adult living donor liver transplantation:a review of surgical technique and current challenges to expand indication of patients.Am J Transplant 2015;15:17-38[PMID:25358749 DOI:10.1111/ajt.12907]
21 Goldaracena N,Echeverri J,Selzner M.Small-for-size syndrome in live donor liver transplantation-Pathways of injury and therapeutic strategies.Clin Transplant 2017;31[PMID:27935645DOI:10.1111/ctr.12885]
22 Graham JA,Samstein B,Emond JC.Early Graft Dysfunction in Living Donor Liver Transplantation and the Small for Size Syndrome.Curr Transplant Rep 2014;1:43-52[PMID:27280080DOI:10.1007/s40472-013-0006-1]
23 Botha JF,Langnas AN,Campos BD,Grant WJ,Freise CE,Ascher NL,Mercer DF,Roberts JP.Left lobe adult-to-adult living donor liver transplantation:small grafts and hemiportocaval shunts in the prevention of small-for-size syndrome.Liver Transpl 2010;16:649-657[PMID:20440774 DOI:10.1002/lt.22043]
24 Goralczyk AD,Obed A,Beham A,Tsui TY,Lorf T.Posterior cavoplasty:a new approach to avoid venous outflow obstruction and symptoms for small-for-size syndrome in right lobe living donor liver transplantation.Langenbecks Arch Surg 2011;396:389-395[PMID:21207055 DOI:10.1007/s00423-010-0736-9]
25 Soejima Y,Shimada M,Suehiro T,Hiroshige S,Ninomiya M,Shiotani S,Harada N,Hideki I,Yonemura Y,Maehara Y.Outcome analysis in adult-to-adult living donor liver transplantation using the left lobe.Liver Transpl 2003;9:581-586[PMID:12783399DOI:10.1053/jlts.2003.50114]
26 Ben-Haim M,Emre S,Fishbein TM,Sheiner PA,Bodian CA,Kim-Schluger L,Schwartz ME,Miller CM.Critical graft size in adult-to-adult living donor liver transplantation:impact of the recipient’s disease.Liver Transpl 2001;7:948-953[PMID:11699030 DOI:10.1053/jlts.2001.29033]
27 Sudhindran S,Menon RN,Balakrishnan D.Challenges and Outcome of Left-lobe Liver Transplants in Adult Living Donor Liver Transplants.J Clin Exp Hepatol 2012;2:181-187[PMID:25755426 DOI:10.1016/S0973-6883(12)60106-6]
28 Yi NJ,Suh KS,Cho YB,Lee HW,Cho EH,Cho JY,Shin WY,Kim J,Lee KU.The right small-for-size graft results in better outcomes than the left small-for-size graft in adult-to-adult living donor liver transplantation.World J Surg 2008;32:1722-1730[PMID:18553047 DOI:10.1007/s00268-008-9641-6]
29 Soejima Y,Shirabe K,Taketomi A,Yoshizumi T,Uchiyama H,Ikegami T,Ninomiya M,Harada N,Ijichi H,Maehara Y.Left lobe living donor liver transplantation in adults.Am JTransplant 2012;12:1877-1885[PMID:22429497 DOI:10.1111/j.1600-6143.2012.04022.x]
30 Gruttadauria S,Pagano D,Liotta R,Tropea A,Tuzzolino F,Marrone G,Mamone G,Marsh JW,Miraglia R,Luca A,Vizzini G,Gridelli BG.Liver Volume Restoration and Hepatic Microarchitecture in Small-for-Size Syndrome.Ann Transplant2015;20:381-389[PMID:26148966 DOI:10.12659/AOT.894082]
31 Shoreem H,Gad EH,Soliman H,Hegazy O,Saleh S,Zakaria H,Ayoub E,Kamel Y,Abouelella K,Ibrahim T,Marawan I.Small for size syndrome difficult dilemma:Lessons from 10 years single centre experience in living donor liver transplantation.World JHepatol 2017;9:930-944[PMID:28824744 DOI:10.4254/wjh.v9.i21.930]
32 Lauro A,Diago Uso T,Quintini C,Di Benedetto F,Dazzi A,De Ruvo N,Masetti M,Cautero N,Risaliti A,Zanfi C,Ramacciato G,Begliomini B,Siniscalchi A,Miller CM,Pinna AD.Adult-to-adult living donor liver transplantation using left lobes:the importance of surgical modulations on portal graft inflow.Transplant Proc2007;39:1874-1876[PMID:17692638 DOI:10.1016/j.transproce ed.2007.05.052]
33 Kim DG,Moon IS,Kim SJ,Lee YJ,Lee MD.Effect of middle hepatic vein reconstruction in living donor liver transplantation using right lobe.Transplant Proc 2006;38:2099-2101[PMID:16980012 DOI:10.1016/j.transproceed.2006.06.005]
34 Peng CJ,Wang XF,Li B,Wei YG,Yan LN,Wen TF,Yang JY,Wang WT,Zhao JC.Efficacy of middle hepatic vein reconstruction in adult right-lobe living donor liver transplantation.Hepatobiliary Pancreat Dis Int 2010;9:135-138[PMID:20382582]
35 Wu H,Yan LN,Li B,Zeng Y,Wen TF,Zhao JC,Wang WT,Yang JY,Xu MQ,Chen ZY,Lu Q,Luo HZ,Li J.Hepatic venous outflow reconstruction in right lobe graft without middle hepatic vein.Hepatol Res 2007;37:1044-1051[PMID:17645520 DOI:10.1111/j.1872-034X.2007.00121.x]
36 Asakuma M,Fujimoto Y,Bourquain H,Uryuhara K,Hayashi M,Tanigawa N,Peitgen HO,Tanaka K.Graft selection algorithm based on congestion volume for adult living donor liver transplantation.Am J Transplant 2007;7:1788-1796[PMID:17524079 DOI:10.1111/j.1600-6143.2007.01849.x]
37 Navasa M,Feu F,García-Pagán JC,Jiménez W,Llach J,Rimola A,Bosch J,Rodés J.Hemodynamic and humoral changes after liver transplantation in patients with cirrhosis.Hepatology 1993;17:355-360[PMID:8444409]
38 Matsudaira S,Ishizaki Y,Yoshimoto J,Fujiwara N,Kawasaki S.Risk Factors for Intractable Ascites After Adult-to-Adult Living Donor Liver Transplantation Using Left Lobe.Transplant Direct 2017;3:e138[PMID:28361122 DOI:10.1097/TXD.0000000000000652]
39 Mukhtar A,Dabbous H.Modulation of splanchnic circulation:Role in perioperative management of liver transplant patients.World J Gastroenterol 2016;22:1582-1592[PMID:26819524DOI:10.3748/wjg.v22.i4.1582]
40 Kanetkar AV,Balakrishnan D,Sudhindran S,Dhar P,Gopalakrishnan U,Menon R,Sudheer OV.Is Portal Venous Pressure or Porto-systemic Gradient Really A Harbinger of Poor Outcomes After Living Donor Liver Transplantation?J Clin Exp Hepatol 2017;7:235-246[PMID:28970711 DOI:10.1016/j.jceh.2017.01.114]
41 Ikegami T,Shirabe K,Yoshizumi T,Aishima S,Taketomi YA,Soejima Y,Uchiyama H,Kayashima H,Toshima T,Maehara Y.Primary graft dysfunction after living donor liver transplantation is characterized by delayed functional hyperbilirubinemia.Am JTransplant 2012;12:1886-1897[PMID:22494784 DOI:10.1111/j.1600-6143.2012.04052.x]
42 Demetris AJ,Kelly DM,Eghtesad B,Fontes P,Wallis Marsh J,Tom K,Tan HP,Shaw-Stiffel T,Boig L,Novelli P,Planinsic R,Fung JJ,Marcos A.Pathophysiologic observations and histopathologic recognition of the portal hyperperfusion or smallfor-size syndrome.Am J Surg Pathol 2006;30:986-993[PMID:16861970]
43 Uemura T,Wada S,Kaido T,Mori A,Ogura Y,Yagi S,Fujimoto Y,Ogawa K,Hata K,Yoshizawa A,Okajima H,Uemoto S.How far can we lower graft-to-recipient weight ratio for living donor liver transplantation under modulation of portal venous pressure?Surgery 2016;159:1623-1630[PMID:26936527 DOI:10.1016/j.surg.2016.01.009]
44 Takahashi Y,Matsuura T,Yoshimaru K,Yanagi Y,Hayashida M,Taguchi T.Liver graft-to-spleen volume ratio as a useful predictive factor of the early graft function in children and young adults transplanted for biliary atresia:a retrospective study.Transpl Int2018;31:620-628[PMID:29424478 DOI:10.1111/tri.13131]
45 Karademir S,Astarcioglu H,Ozbilgin M,Ozkardesler S,Yilmaz T,Akarsu M,Akan M,Ozzeybek D,Obuz F,Astarcioglu I.Efficacy of right anterior sector drainage reconstruction in right-lobe livedonor transplantation.Transplant Proc 2006;38:3582-3584[PMID:17175337 DOI:10.1016/j.transproceed.2006.10.043]
46 Mori S,Park MS,Kim H,Choi Y,Hong G,Yi NJ,Lee KW,Suh KS.Dysfunction in Patients With Small-for-Size Grafts After Living Donor Liver Transplantation.Int Surg 2015;100:524-530[PMID:25785339 DOI:10.9738/INTSURG-D-14-00016.1]
47 Kim SH,Lee EC,Park SJ.Impact of preserved collateral veins on small-for-size grafts in living donor liver transplantation.Hepatol Res 2018;48:295-302[PMID:29125895 DOI:10.1111/hepr.13002]
48 Hessheimer AJ,Fondevila C,TauráP,Mu?oz J,Sánchez O,Fuster J,Rimola A,García-Valdecasas JC.Decompression of the portal bed and twice-baseline portal inflow are necessary for the functional recovery of a“small-for-size”graft.Ann Surg 2011;253:1201-1210[PMID:21587116 DOI:10.1097/SLA.0b013e3181ffb2d7]
49 Xiao L,Li F,Wei B,Li B,Tang CW.Small-for-size syndrome after living donor liver transplantation:successful treatment with a transjugular intrahepatic portosystemic shunt.Liver Transpl 2012;18:1118-1120[PMID:22511462 DOI:10.1002/lt.23457]
50 Sato Y,Oya H,Yamamoto S,Kobayashi T,Hara Y,Kokai H,Hatakeyama K.Method for spontaneous constriction and closure of portocaval shunt using a ligamentum teres hepatis in small-for-size graft liver transplantation.Transplantation 2010;90:1200-1203[PMID:21088651 DOI:10.1097/TP.0b013e3181fa93e0]
51 Nutu OA,Justo Alonso I,Marcacuzco Quinto AA,Calvo Pulido J,Jiménez Romero LC.Complete splenic embolization for the treatment of refractory ascites after liver transplantation.Rev Esp Enferm Dig 2018;110:257-259[PMID:29411988 DOI:10.17235/reed.2018.5338/2017]
52 Badawy A,Hamaguchi Y,Satoru S,Kaido T,Okajima H,Uemoto S.Evaluation of safety of concomitant splenectomy in living donor liver transplantation:a retrospective study.Transpl Int 2017;30:914-923[PMID:28512755 DOI:10.1111/tri.12985]
53 Troisi RI,Berardi G,Tomassini F,Sainz-Barriga M.Graft inflow modulation in adult-to-adult living donor liver transplantation:Asystematic review.Transplant Rev(Orlando)2017;31:127-135[PMID:27989547 DOI:10.1016/j.trre.2016.11.002]
54 Xu Y,Chen H,Yeh H,Wang H,Leng J,Dong J.Living donor liver transplantation using dual grafts:Experience and lessons learned from cases worldwide.Liver Transpl 2015;21:1438-1448[PMID:26336078 DOI:10.1002/lt.24315]
55 Gao W,Zhang L,Zhang Y,Sun C,Chen X,Wang Y.Adiposederived mesenchymal stem cells promote liver regeneration and suppress rejection in small-for-size liver allograft.Transpl Immunol2017;45:1-7[PMID:28778713 DOI:10.1016/j.trim.2017.07.005]
56 Kobayashi T,Sato Y,Yamamoto S,Oya H,Hara Y,Watanabe T,Kokai H,Hatakeyama K.Feasibility of auxiliary partial living donor liver transplantation for fulminant hepatic failure as an aid for small-for-size graft:single center experience.Transplant Proc2009;41:262-264[PMID:19249530 DOI:10.1016/j.transproceed.2008.10.025]
57 Dasari BVM,Schlegel A,Mergental H,Perera MTPR.The use of old donors in liver transplantation.Best Pract Res Clin Gastroenterol 2017;31:211-217[PMID:28624109 DOI:10.1016/j.bpg.2017.03.002]
58 Tanemura A,Mizuno S,Wada H,Yamada T,Nobori T,Isaji S.Donor age affects liver regeneration during early period in the graft liver and late period in the remnant liver after living donor liver transplantation.World J Surg 2012;36:1102-1111[PMID:22374540 DOI:10.1007/s00268-012-1496-1]
59 Abdelfattah MR,Elsiesy H.Reappraisal of upper age limit for adult living-donor liver transplantation using right lobe grafts:an outcome analysis.Eur J Gastroenterol Hepatol 2015;27:593-599[PMID:25822867 DOI:10.1097/MEG.0000000000000322]
60 Ono Y,Kawachi S,Hayashida T,Wakui M,Tanabe M,Itano O,Obara H,Shinoda M,Hibi T,Oshima G,Tani N,Mihara K,Kitagawa Y.The influence of donor age on liver regeneration and hepatic progenitor cell populations.Surgery 2011;150:154-161[PMID:21719061 DOI:10.1016/j.surg.2011.05.004]
61 Akamatsu N,Sugawara Y,Tamura S,Kaneko J,Matsui Y,Togashi J,Makuuchi M.Impact of live donor age on liver transplantation.Transplant Proc 2007;39:3189-3193[PMID:18089350 DOI:10.1016/j.transproceed.2007.03.116]
62 Kawano Y,Ishikawa N,Aida J,Sanada Y,Izumiyama-Shimomura N,Nakamura K,Poon SS,Matsumoto K,Mizuta K,Uchida E,Tajiri T,Kawarasaki H,Takubo K.Q-FISH measurement of hepatocyte telomere lengths in donor liver and graft after pediatric living-donor liver transplantation:donor age affects telomere length sustainability.PLo S One 2014;9:e93749[PMID:24727734DOI:10.1371/journal.pone.0093749]
63 Imamura H,Hidaka M,Soyama A,Kitasato A,Adachi T,Ono S,Natsuda K,Hara T,Kugiyama T,Baimakhanov Z,Okada S,Fujita F,Kanetaka K,Takatsuki M,Kuroki T,Eguchi S.A Donor AgeBased and Graft Volume-Based Analysis for Living Donor Liver Transplantation in Elderly Recipients.Transplant Direct 2017;3:e168[PMID:28706971 DOI:10.1097/TXD.0000000000000688]
64 Dayangac M,Taner CB,Yaprak O,Demirbas T,Balci D,Duran C,Yuzer Y,Tokat Y.Utilization of elderly donors in living donor liver transplantation:when more is less?Liver Transpl 2011;17:548-555[PMID:21506243 DOI:10.1002/lt.22276]
65 Yoshizumi T,Taketomi A,Uchiyama H,Harada N,Kayashima H,Yamashita Y,Soejima Y,Shimada M,Maehara Y.Graft size,donor age,and patient status are the indicators of early graft function after living donor liver transplantation.Liver Transpl 2008;14:1007-1013[PMID:18581462 DOI:10.1002/lt.21462]
66 Han JH,You YK,Na GH,Kim EY,Lee SH,Hong TH,Kim DG.Outcomes of living donor liver transplantation using elderly donors.Ann Surg Treat Res 2014;86:184-191[PMID:24783177DOI:10.4174/astr.2014.86.4.184]
67 Kamo N,Kaido T,Hammad A,Ogawa K,Fujimoto Y,Uemura T,Mori A,Hatano E,Okajima H,Uemoto S.Impact of elderly donors for liver transplantation:A single-center experience.Liver Transpl2015;21:591-598[PMID:25641778 DOI:10.1002/lt.24086]
68 Shin M,Moon HH,Kim JM,Park JB,Kwon CH,Kim SJ,Joh JW.Importance of donor-recipient age gradient to the prediction of graft outcome after living donor liver transplantation.Transplant Proc 2013;45:3005-3012[PMID:24157024 DOI:10.1016/j.trans proceed.2013.08.018]
69 Kubota T,Hata K,Sozu T,Ueda Y,Hirao H,Okamura Y,Tamaki I,Yoshikawa J,Kusakabe J,Tanaka H,Kageyama S,Anazawa T,Yoshizawa A,Yagi S,Yamashiki N,Okajima H,Kaido T,Uemoto S.Impact of Donor Age on Recipient Survival in Adult-to-Adult Living-donor Liver Transplantation.Ann Surg 2018;267:1126-1133[PMID:28288061 DOI:10.1097/SLA.0000000000002194]
70 Katsuragawa H,Yamamoto M,Katagiri S,Yoshitoshi K,Ariizumi S,Kotera Y,Takahashi Y,Takasaki K.Graft size and donor age are independent factors for graft loss in adult-to-adult living-donor liver transplantation using the left liver.J Hepatobiliary Pancreat Surg 2009;16:178-183[PMID:19165414 DOI:10.1007/s00534-008-0026-x]
71 Selzner N,Girgrah N,Lilly L,Guindi M,Selzner M,Therapondos G,Adeyi O,Mc Gilvray I,Cattral M,Greig PD,Grant D,Levy G,Renner EL.The difference in the fibrosis progression of recurrent hepatitis C after live donor liver transplantation versus deceased donor liver transplantation is attributable to the difference in donor age.Liver Transpl 2008;14:1778-1786[PMID:19025914 DOI:10.1002/lt.21598]
72 Wang K,Jiang WT,Deng YL,Pan C,Shen ZY.Effect of donor age on graft function and long-term survival of recipients undergoing living donor liver transplantation.Hepatobiliary Pancreat Dis Int2015;14:50-55[PMID:25655290]
73 Ikegami T,Taketomi A,Ohta R,Soejima Y,Yoshizumi T,Shimada M,Maehara Y.Donor age in living donor liver transplantation.Transplant Proc 2008;40:1471-1475[PMID:18589131 DOI:10.1016/j.transproceed.2008.02.084]
74 Li C,Wen TF,Yan LN,Li B,Yang JY,Xu MQ,Wang WT,Wei YG.Safety of living donor liver transplantation using older donors.J Surg Res 2012;178:982-987[PMID:22835951 DOI:10.1016/j.jss.2012.06.065]
75 Goldaracena N,Sapisochin G,Spetzler V,Echeverri J,Kaths M,Cattral MS,Greig PD,Lilly L,Mc Gilvray ID,Levy GA,Ghanekar A,Renner EL,Grant DR,Selzner M,Selzner N.Live Donor Liver Transplantation With Older(≥50 Years)Versus Younger Donors:Does Age Matter?Ann Surg 2016;263:979-985[PMID:26106842DOI:10.1097/SLA.0000000000001337]
76 Kim SH,Lee EC,Shim JR,Park SJ.Right lobe living donors ages55 years old and older in liver transplantation.Liver Transpl 2017;23:1305-1311[PMID:28734130 DOI:10.1002/lt.24823]
77 Starzl TE,Koep LJ,Halgrimson CG,Hood J,Schroter GP,Porter KA,Weil R 3rd.Fifteen years of clinical liver transplantation.Gastroenterology 1979;77:375-388[PMID:376395]
78 Sanchez-Urdazpal L,Sterioff S,Janes C,Schwerman L,Rosen C,Krom RA.Increased bile duct complications in ABO incompatible liver transplant recipients.Transplant Proc 1991;23:1440-1441[PMID:1989259]
79 Gugenheim J,Samuel D,Fabiani B,Saliba F,Castaing D,Reynes M,Bismuth H.Rejection of ABO incompatible liver allografts in man.Transplant Proc 1989;21:2223-2224[PMID:2652718]
80 Miyata R,Shimazu M,Tanabe M,Kawachi S,Hoshino K,Wakabayashi G,Kawai Y,Kitajima M.Clinical characteristics of thrombotic microangiopathy following ABO incompatible living donor liver transplantation.Liver Transpl 2007;13:1455-1462[PMID:17902122 DOI:10.1002/lt.21253]
81 Oya H,Sato Y,Yamamoto S,Nakatsuka H,Kobayashi T,Watanabe T,Kokai H,Hatakeyama K.Thrombotic microangiopathy after ABO-incompatible living donor liver transplantation:a case report.Transplant Proc 2008;40:2549-2551[PMID:18929797 DOI:10.1016/j.transproceed.2008.07.117]
82 Kishida N,Shinoda M,Itano O,Obara H,Kitago M,Hibi T,Yagi H,Abe Y,Matsubara K,Odaira M,Tanabe M,Shimazu M,Kitagawa Y.Increased Incidence of Thrombotic Microangiopathy After ABO-Incompatible Living Donor Liver Transplantation.Ann Transplant 2016;21:755-764[PMID:27956735]
83 Song GW,Lee SG,Hwang S,Kim KH,Ahn CS,Moon DB,Ha TY,Jung DH,Park GC,Kang SH,Jung BH,Yoon YI,Kim N.Biliary stricture is the only concern in ABO-incompatible adult living donor liver transplantation in the rituximab era.JHepatol 2014;61:575-582[PMID:24801413 DOI:10.1016/j.jhep.2014.04.039]
84 Ikegami T,Yoshizumi T,Soejima Y,Uchiyama H,Shirabe K,Maehara Y.Feasible usage of ABO incompatible grafts in living donor liver transplantation.Hepatobiliary Surg Nutr 2016;5:91-97[PMID:27115002 DOI:10.3978/j.issn.2304-3881.2015.06.02]
85 Sanchez-Urdazpal L,Batts KP,Gores GJ,Moore SB,Sterioff S,Wiesner RH,Krom RA.Increased bile duct complications in liver transplantation across the ABO barrier.Ann Surg 1993;218:152-158[PMID:8342994]
86 Demetris AJ,Jaffe R,Tzakis A,Ramsey G,Todo S,Belle S,Esquivel C,Shapiro R,Markus B,Mroczek E.Antibody-mediated rejection of human orthotopic liver allografts.A study of liver transplantation across ABO blood group barriers.Am J Pathol1988;132:489-502[PMID:3046369]
87 Choi SH,Kim KW,Kim SY,Kim JS,Kwon JH,Song GW,Lee SG.Computed tomography findings in ABO-incompatible living donor liver transplantation recipients with biliary strictures.Eur Radiol 2018;28:2572-2581[PMID:29294154 DOI:10.1007/s00330-017-5226-9]
88 Yamada Y,Hoshino K,Shimojima N,Shinoda M,Obara H,Kawachi S,Fuchimoto Y,Tanabe M,Kitagawa Y,Morikawa Y.Idiopathic hypereosinophilic syndrome in a case with ABO-incompatible liver transplantation for biliary atresia complicated by portal vein thrombosis.Pediatr Transplant 2010;14:e49-e53[PMID:20042017 DOI:10.1111/j.1399-3046.2009.01170.x]
89 Kawagishi N,Takeda I,Miyagi S,Satoh K,Akamatsu Y,Sekiguchi S,Satomi S.Long-term outcome of ABO-incompatible living-donor liver transplantation:a single-center experience.JHepatobiliary Pancreat Surg 2009;16:468-472[PMID:19333538DOI:10.1007/s00534-009-0074-x]
90 Yoon YI,Song GW,Lee SG,Hwang S,Kim KH,Kim SH,Kang WH,Cho HD,Jwa EK,Kwon JH,Tak EY,Kirchner VA.Outcome of ABO-incompatible adult living-donor liver transplantation for patients with hepatocellular carcinoma.J Hepatol 2018;68:1153-1162[PMID:29452208 DOI:10.1016/j.jhep.2018.02.002]
91 Sakai H,Tanaka Y,Tazawa H,Shimizu S,Verma S,Ohira M,Tahara H,Ide K,Ishiyama K,Kobayashi T,Onoe T,Ohdan H.Effect of Fc-γReceptor Polymorphism on Rituximab-Mediated B Cell Depletion in ABO-Incompatible Adult Living Donor Liver Transplantation.Transplant Direct 2017;3:e164[PMID:28620648 DOI:10.1097/TXD.0000000000000683]
92 Egawa H,Umeshita K,Uemoto S.Optimal dosage regimen for rituximab in ABO-incompatible living donor liver transplantation.J Hepatobiliary Pancreat Sci 2017;24:89-94[PMID:28002655DOI:10.1002/jhbp.419]
93 Ikegami T,Taketomi A,Soejima Y,Iguchi T,Sanefuji K,Kayashima H,Yoshizumi T,Harada N,Maehara Y.Successful ABO incompatible living donor liver transplantation in a patient with high isoagglutinin titer using high-dose intravenous immunoglobulin.Transplant Proc 2007;39:3491-3494[PMID:18089417 DOI:10.1016/j.transproceed.2007.09.028]
94 Ikegami T,Taketomi A,Soejima Y,Yoshizumi T,Uchiyama H,Harada N,Iguchi T,Hashimoto N,Maehara Y.Rituximab,IVIG,and plasma exchange without graft local infusion treatment:a new protocol in ABO incompatible living donor liver transplantation.Transplantation 2009;88:303-307[PMID:19667930 DOI:10.1097/TP.0b013e3181adcae6]
95 Usui M,Isaji S,Mizuno S,Sakurai H,Uemoto S.Experiences and problems pre-operative anti-CD20 monoclonal antibody infusion therapy with splenectomy and plasma exchange for ABO-incompatible living-donor liver transplantation.Clin Transplant 2007;21:24-31[PMID:17302588 DOI:10.1111/j.1399-0012.2006.00572.x]
96 Chen G,Sun J,Wei S,Chen Y,Tang G,Xie Z,Xu H,Chen J,Zhao H,Yuan Z,Wang W,Liu G,Wang B,Niu B.Simultaneous ABO-incompatible living-donor liver transplantation and splenectomy without plasma exchange in China:Two case reports.J Int Med Res 2017;45:2146-2152[PMID:28635356 DOI:10.1177/0300060517710407]
97 Uchiyama H,Mano Y,Taketomi A,Soejima Y,Yoshizumi T,Ikegami T,Shirabe K,Maehara Y.Kinetics of anti-blood type isoagglutinin titers and B lymphocytes in ABO-incompatible living donor liver transplantation with rituximab and plasma exchange.Transplantation 2011;92:1134-1139[PMID:21946174 DOI:10.1097/TP.0b013e318231e9f8]
98 Soin AS,Raut V,Mohanka R,Rastogi A,Goja S,Balachandran M,Saigal S,Saraf N,Bhangui P,Sumana KR,Singla P,Srinivasan T,Choudhary N,Tiwari A,Raina V,Govil D,Mohan N,Vohra V.Use of ABO-incompatible grafts in living donor liver transplantation--first report from India.Indian J Gastroenterol 2014;33:72-76[PMID:24369388 DOI:10.1007/s12664-013-0424-0]
99 Rummler S,Bauschke A,Baerthel E,Juette H,Maier K,Malessa C,Barz D,Settmacher U.ABO-Incompatible Living Donor Liver Transplantation in Focus of Antibody Rebound.Transfus Med Hemother 2017;44:46-51[PMID:28275333 DOI:10.1159/000450792]
100 Kim JD,Choi DL,Kim SG,Lee AJ.Single-Center Experience of ABO-Incompatible Living-Donor Liver Transplantation With a New Simplified Intravenous Immunoglobulin Protocol:APropensity Score-Matching Analysis.Transplant Proc 2016;48:1134-1138[PMID:27320573 DOI:10.1016/j.transproceed.2016.02.040]
101 Kim JM,Kwon CH,Joh JW,Kang ES,Park JB,Lee JH,Kim SJ,Paik SW,Lee SK,Kim DW.ABO-incompatible living donor liver transplantation is suitable in patients without ABO-matched donor.J Hepatol 2013;59:1215-1222[PMID:23928408 DOI:10.1016/j.jhep.2013.07.035]
102 Kawagishi N,Satoh K,Enomoto Y,Akamatsu Y,Sekiguchi S,Fukumori T,Fujimori K,Satomi S.New strategy for ABO-incompatible living donor liver transplantation with anti-CD20antibody(rituximab)and plasma exchange.Transplant Proc 2005;37:1205-1206[PMID:15848670 DOI:10.1016/j.transproceed.2004.12.114]
103 Kim SH,Lee EC,Shim JR,Park SJ.A simplified protocol using rituximab and immunoglobulin for ABO-incompatible low-titre living donor liver transplantation.Liver Int 2018;38:932-939[PMID:29053910 DOI:10.1111/liv.13614]
104 Yoshizawa A,Sakamoto S,Ogawa K,Kasahara M,Uryuhara K,Oike F,Ueda M,Takada Y,Egawa H,Tanaka K.New protocol of immunosuppression for liver transplantation across ABO barrier:the use of Rituximab,hepatic arterial infusion,and preservation of spleen.Transplant Proc 2005;37:1718-1719[PMID:15919443DOI:10.1016/j.transproceed.2005.03.148]
105 Egawa H,Teramukai S,Haga H,Tanabe M,Fukushima M,Shimazu M.Present status of ABO-incompatible living donor liver transplantation in Japan.Hepatology 2008;47:143-152[PMID:17929298 DOI:10.1002/hep.21928]
106 Yamamoto H,Uchida K,Kawabata S,Isono K,Miura K,Hayashida S,Oya Y,Sugawara Y,Inomata Y.Feasibility of Monotherapy by Rituximab Without Additional Desensitization in ABO-incompatible Living-Donor Liver Transplantation.Transplantation 2018;102:97-104[PMID:28938311 DOI:10.1097/TP.0000000000001956]
107 Jiménez-Castro MB,Negrete-Sánchez E,Casillas-Ramírez A,Gulfo J,álvarez-Mercado AI,Cornide-Petronio ME,GraciaSancho J,Rodés J,Peralta C.The effect of cortisol in rat steatotic and non-steatotic liver transplantation from brain-dead donors.Clin Sci(Lond)2017;131:733-746[PMID:28246131 DOI:10.1042/CS20160676]
108 Xue M,Lv C,Chen X,Liang J,Zhao C,Zhang Y,Huang X,Sun Q,Wang T,Gao J,Zhou J,Yu M,Fan J,Gao X.Donor liver steatosis:A risk factor for early new-onset diabetes after liver transplantation.J Diabetes Investig 2017;8:181-187[PMID:27511316 DOI:10.1111/jdi.12560]
109 Perkins JD.Saying“Yes”to obese living liver donors:short-term intensive treatment for donors with hepatic steatosis in livingdonor liver transplantation.Liver Transpl 2006;12:1012-1013[PMID:16721781 DOI:10.1002/lt.20807]
110 Kotecha HL,Saraf N,Saigal S,Choudhary NS,Yadav A,Mohanka R,Rastogi A,Menon PB,Goja S,Soin AS.NAFLDis the leading cause of donor rejection in living donor liver transplantation.J Clin Exp Hepatol 2013;3:S116[DOI:10.1016/j.jceh.2013.03.201]
111 Cho JY,Suh KS,Shin WY,Lee HW,Yi NJ,Kim MA,Jang JJ,Lee KU.Expansion of hepatic progenitor cell in fatty liver graft after living donor liver transplantation.Transpl Int 2010;23:530-537[PMID:20003044 DOI:10.1111/j.1432-2277.2009.01020.x]
112 Cho JY,Suh KS,Lee HW,Cho EH,Yang SH,Cho YB,Yi NJ,Kim MA,Jang JJ,Lee KU.Hepatic steatosis is associated with intrahepatic cholestasis and transient hyperbilirubinemia during regeneration after living donor liver transplantation.Transpl Int 2006;19:807-813[PMID:16961772 DOI:10.1111/j.1432-2277.2006.00355.x]
113 Cho JY,Suh KS,Kwon CH,Yi NJ,Cho SY,Jang JJ,Kim SH,Lee KU.The hepatic regeneration power of mild steatotic grafts is not impaired in living-donor liver transplantation.Liver Transpl 2005;11:210-217[PMID:15666394 DOI:10.1002/lt.20340]
114 Gao F,Xu X,Ling Q,Wu J,Zhou L,Xie HY,Wang HP,Zheng SS.Efficacy and safety of moderately steatotic donor liver in transplantation.Hepatobiliary Pancreat Dis Int 2009;8:29-33[PMID:19208511]
115 Knaak M,Goldaracena N,Doyle A,Cattral MS,Greig PD,Lilly L,Mc Gilvray ID,Levy GA,Ghanekar A,Renner EL,Grant DR,Selzner M,Selzner N.Donor BMI;30 Is Not a Contraindication for Live Liver Donation.Am J Transplant 2017;17:754-760[PMID:27545327 DOI:10.1111/ajt.14019]
116 Han S,Ha SY,Park CK,Joh JW,Kwon CH,Kwon GY,Kim G,Gwak MS,Jeong WK,Ko JS.Microsteatosis may not interact with macrosteatosis in living donor liver transplantation.JHepatol 2015;62:556-562[PMID:25450710 DOI:10.1016/j.jhep.2014.10.027]
117 Oshita A,Tashiro H,Amano H,Kobayashi T,Onoe T,Ide K,Takaki S,Takahashi S,Arihiro K,Chayama K,Ohdan H.Safety and feasibility of diet-treated donors with steatotic livers at the initial consultation for living-donor liver transplantation.Transplantation 2012;93:1024-1030[PMID:22495493 DOI:10.1097/TP.0b013e31824c9e25]
118 Nakamuta M,Morizono S,Soejima Y,Yoshizumi T,Aishima S,Takasugi S,Yoshimitsu K,Enjoji M,Kotoh K,Taketomi A,Uchiyama H,Shimada M,Nawata H,Maehara Y.Short-term intensive treatment for donors with hepatic steatosis in livingdonor liver transplantation.Transplantation 2005;80:608-612[PMID:16177634]
119 Choudhary NS,Saraf N,Saigal S,Gautam D,Lipi L,Rastogi A,Goja S,Menon PB,Bhangui P,Ramchandra SK,Soin AS.Rapid Reversal of Liver Steatosis With Life Style Modification in Highly Motivated Liver Donors.J Clin Exp Hepatol 2015;5:123-126[PMID:26155039 DOI:10.1016/j.jceh.2015.04.002]
120 Moon D,Lee S,Hwang S,Kim K,Ahn C,Park K,Ha T,Song G.Resolution of severe graft steatosis following dual-graft living donor liver transplantation.Liver Transpl 2006;12:1156-1160[PMID:16799937 DOI:10.1002/lt.20814]
121 Wang SH,Loh PY,Lin TL,Lin LM,Li WF,Lin YH,Lin CC,Chen CL.Active immunization for prevention of De novo hepatitis B virus infection after adult living donor liver transplantation with a hepatitis B core antigen-positive graft.Liver Transpl 2017;23:1266-1272[PMID:28691231 DOI:10.1002/lt.24814]
122 Xi ZF,Xia Q,Zhang JJ,Chen XS,Han LZ,Zhu JJ,Wang SY,Qiu DK.De novo hepatitis B virus infection from anti-HBcpositive donors in pediatric living donor liver transplantation.J DigDis 2013;14:439-445[PMI D:23638710DOI:10.1111/1751-2980.12066]
123 Dong C,Gao W,Ma N,Sun C,Zheng WP,Wang K,Shen ZY.Risks and treatment strategies for de novo hepatitis B virus infection from anti-HBc-positive donors in pediatric living donor liver transplantation.Pediatr Transplant 2017;21[PMID:27933716 DOI:10.1111/petr.12854]
124 Loggi E,Conti F,Cucchetti A,Ercolani G,Pinna AD,Andreone P.Liver grafts from hepatitis B surface antigen-positive donors:A review of the literature.World J Gastroenterol 2016;22:8010-8016[PMID:27672295 DOI:10.3748/wjg.v22.i35.8010]
125 Lei J,Yan L,Wang W.A comprehensive study of the safety of using anti-hepatitis B core(Hbc)positive subjects in living donor liver transplants.Hepatogastroenterology 2013;60:1426-1432[PMID:23933935 DOI:10.5754/hge13062]
126 Lin CC,Chen CL,Concejero A,Wang CC,Wang SH,Liu YW,Yang CH,Yong CC,Lin TS,Jawan B,Cheng YF,Eng HL.Active immunization to prevent de novo hepatitis B virus infection in pediatric live donor liver recipients.Am J Transplant 2007;7:195-200[PMID:17227568 DOI:10.1111/j.1600-6143.2006.01618.x]
127 Hara Y,Tokodai K,Nakanishi C,Miyagi S,Kawagishi N.Spontaneous resolution of de novo hepatitis B after living donor liver transplantation with hepatitis B core antibody positive graft:a case report.Surg Case Rep 2016;2:118[PMID:27797067 DOI:10.1186/s40792-016-0246-2]
128 Sasaki R,Kanda T,Ohtsuka M,Yasui S,Haga Y,Nakamura M,Yokoyama M,Wu S,Nakamoto S,Arai M,Maruyama H,Miyazaki M,Yokosuka O.Successful Management of Graft Reinfection of HCV Genotype 2 in Living Donor Liver Transplantation from a Hepatitis B Core Antibody-Positive Donor with Sofosbuvir and Ribavirin.Case Rep Gastroenterol 2016;10:366-372[PMID:27721720 DOI:10.1159/000447423]
129 Hwang S,Lee SG,Park KM,Kim KH,Ahn CS,Oh HB,Moon DB,Ha TY,Lim YS,Jung DH.Five-year follow-up of a hepatitis B virus-positive recipient of hepatitis B surface antigen-positive living donor liver graft.Liver Transpl 2006;12:993-997[PMID:16721765 DOI:10.1002/lt.20799]
130 Soejima Y,Shimada M,Taketomi A,Yoshizumi T,Uchiyama H,Ikegami T,Nakamuta M,Maehara Y.Successful living donor liver transplantation using a graft from a hepatitis B surface antigenpositive donor.Liver Int 2007;27:1282-1286[PMID:17919241DOI:10.1111/j.1478-3231.2007.01528.x]
131 Jeng LB,Thorat A,Yang HR,Yeh CC,Chen TH,Hsu CH,Hsu SC,Poon KS,Li PC,Lai HC,Su WP,Peng CY.Successful use of hepatitis B surface antigen-positive liver grafts-an effective source for donor organs in endemic areas:a single-center experience.Ann Transplant 2015;20:103-111[PMID:25703063 DOI:10.12659/AOT.893032]
132 Tang Z,Li X,Wu S,Liu Y,Qiao Y,Xu D,Li J.Risk of hepatitis B reactivation in HBs Ag-negative/HBc Ab-positive patients with undetectable serum HBV DNA after treatment with rituximab for lymphoma:a meta-analysis.Hepatol Int 2017;11:429-433[PMID:28856548 DOI:10.1007/s12072-017-9817-y]
133 Li G,Mu X,Huang X,Qian X,Qin J,Tan Z,Zhang W,Xu X,Tan S,Zhu Z,Li W,Wang X,Wang X,Sun B.Liver transplantation using the otherwise-discarded partial liver resection graft with hepatic benign tumor:Analysis of a preliminary experience on 15consecutive cases.Medicine(Baltimore)2017;96:e7295[PMID:28723742 DOI:10.1097/MD.0000000000007295]
134 Fuchino M,Tajiri K,Minemura M,Sugiyama T.Vanishing Tumor in a Liver Graft from a Hepatitis B Virus Surface AntigenPositive Donor.Case Rep Gastroenterol 2017;11:610-615[PMID:29118691 DOI:10.1159/000481164]
2 Makuuchi M,Kawasaki S,Noguchi T,Hashikura Y,Matsunami H,Hayashi K,Harada H,Kakazu T,Takayama T,Kawarasaki H.Donor hepatectomy for living related partial liver transplantation.Surgery 1993;113:395-402[PMID:8456395]
3 Makuuchi M,Kawarazaki H,Iwanaka T,Kamada N,Takayama T,Kumon M.Living related liver transplantation.Surg Today 1992;22:297-300[PMID:1392338]
4 Routh D,Sharma S,Naidu CS,Rao PP,Sharma AK,Ranjan P.Comparison of outcomes in ideal donor and extended criteria donor in deceased donor liver transplant:a prospective study.Int J Surg 2014;12:774-777[PMID:24947949 DOI:10.1016/j.ijsu.2014.06.003]
5 Nure E,Lirosi MC,Frongillo F,Bianco G,Silvestrini N,Fiorillo C,Sganga G,Agnes S.Overextended Criteria Donors:Experience of an Italian Transplantation Center.Transplant Proc 2015;47:2102-2105[PMID:26361653 DOI:10.1016/j.transproceed.2014.11.077]
6 Laing RW,Mergental H,Yap C,Kirkham A,Whilku M,Barton D,Curbishley S,Boteon YL,Neil DA,Hübscher SG,Perera MTPR,Muiesan P,Isaac J,Roberts KJ,Cilliers H,Afford SC,Mirza DF.Viability testing and transplantation of marginal livers(VITTAL)using normothermic machine perfusion:study protocol for an open-label,non-randomised,prospective,single-arm trial.BMJ Open 2017;7:e017733[PMID:29183928 DOI:10.1136/bmjopen-2017-017733]
7 Nemes B,Gelley F,Zádori G,Piros L,Perneczky J,Kóbori L,Fehérvári I,G?r?g D.Outcome of liver transplantation based on donor graft quality and recipient status.Transplant Proc 2010;42:2327-2330[PMID:20692473 DOI:10.1016/j.transproceed.2010.05.018]
8 Giretti G,Barbier L,Bucur P,Marques F,Perarnau JM,Ferrandière M,Tellier AC,Kerouredan V,Altieri M,Causse X,Debette-Gratien M,Silvain C,SalaméE.Recipient Selection for Optimal Utilization of Discarded Grafts in Liver Transplantation.Transplantation 2018;102:775-782[PMID:29298235 DOI:10.1097/TP.0000000000002069]
9 Dirican A,Baskiran A,Dogan M,Ates M,Soyer V,Sarici B,Ozdemir F,Polat Y,Yilmaz S.Evaluation of Potential Donors in Living Donor Liver Transplantation.Transplant Proc 2015;47:1315-1318[PMID:26093708 DOI:10.1016/j.transproceed.2015.04.045]
10 Kiuchi T,Kasahara M,Uryuhara K,Inomata Y,Uemoto S,Asonuma K,Egawa H,Fujita S,Hayashi M,Tanaka K.Impact of graft size mismatching on graft prognosis in liver transplantation from living donors.Transplantation 1999;67:321-327[PMID:10075602]
11 Lee DS,Gil WH,Lee HH,Lee KW,Lee SK,Kim SJ,Choi SH,Heo JS,Hyon WS,Kim GS,Paik SW,Koh KC,Joh JW.Factors affecting graft survival after living donor liver transplantation.Transplant Proc 2004;36:2255-2256[PMID:15561210 DOI:10.1016/j.transproceed.2004.08.073]
12 Fan ST,Lo CM,Liu CL,Yong BH,Wong J.Determinants of hospital mortality of adult recipients of right lobe live donor liver transplantation.Ann Surg 2003;238:864-869;discussion 869-870[PMID:14631223 DOI:10.1097/01.sla.0000098618.11382.77]
13 Moon JI,Kwon CH,Joh JW,Jung GO,Choi GS,Park JB,Kim JM,Shin M,Kim SJ,Lee SK.Safety of small-for-size grafts in adult-to-adult living donor liver transplantation using the right lobe.Liver Transpl 2010;16:864-869[PMID:20583075 DOI:10.1002/lt.22094]
14 Lan X,Li B,Wang XF,Peng CJ,Wei YG,Yan LN.[Feasibility of small size graft following living donor liver transplantation].Zhonghua Wai Ke Za Zhi 2009;47:1218-1220[PMID:19781165]
15 Selzner M,Kashfi A,Cattral MS,Selzner N,Greig PD,Lilly L,Mc Gilvray ID,Therapondos G,Adcock LE,Ghanekar A,Levy GA,Renner EL,Grant DR.A graft to body weight ratio less than 0.8 does not exclude adult-to-adult right-lobe living donor liver transplantation.Liver Transpl 2009;15:1776-1782[PMID:19938139 DOI:10.1002/lt.21955]
16 Chen PX,Yan LN,Wang WT.Outcome of patients undergoing right lobe living donor liver transplantation with small-for-size grafts.World J Gastroenterol 2014;20:282-289[PMID:24415883DOI:10.3748/wjg.v20.i1.282]
17 She WH,Chok KS,Fung JY,Chan AC,Lo CM.Outcomes of right-lobe and left-lobe living-donor liver transplantations using small-for-size grafts.World J Gastroenterol 2017;23:4270-4277[PMID:28694667 DOI:10.3748/wjg.v23.i23.4270]
18 Lee SD,Kim SH,Kim YK,Lee SA,Park SJ.Graft-to-recipient weight ratio lower to 0.7%is safe without portal pressure modulation in right-lobe living donor liver transplantation with favorable conditions.Hepatobiliary Pancreat Dis Int 2014;13:18-24[PMID:24463075]
19 Alim A,Erdogan Y,Yuzer Y,Tokat Y,Oezcelik A.Graft-torecipient weight ratio threshold adjusted to the model for end-stage liver disease score for living donor liver transplantation.Liver Transpl 2016;22:1643-1648[PMID:27509534 DOI:10.1002/lt.24523]
20 Lee SG.A complete treatment of adult living donor liver transplantation:a review of surgical technique and current challenges to expand indication of patients.Am J Transplant 2015;15:17-38[PMID:25358749 DOI:10.1111/ajt.12907]
21 Goldaracena N,Echeverri J,Selzner M.Small-for-size syndrome in live donor liver transplantation-Pathways of injury and therapeutic strategies.Clin Transplant 2017;31[PMID:27935645DOI:10.1111/ctr.12885]
22 Graham JA,Samstein B,Emond JC.Early Graft Dysfunction in Living Donor Liver Transplantation and the Small for Size Syndrome.Curr Transplant Rep 2014;1:43-52[PMID:27280080DOI:10.1007/s40472-013-0006-1]
23 Botha JF,Langnas AN,Campos BD,Grant WJ,Freise CE,Ascher NL,Mercer DF,Roberts JP.Left lobe adult-to-adult living donor liver transplantation:small grafts and hemiportocaval shunts in the prevention of small-for-size syndrome.Liver Transpl 2010;16:649-657[PMID:20440774 DOI:10.1002/lt.22043]
24 Goralczyk AD,Obed A,Beham A,Tsui TY,Lorf T.Posterior cavoplasty:a new approach to avoid venous outflow obstruction and symptoms for small-for-size syndrome in right lobe living donor liver transplantation.Langenbecks Arch Surg 2011;396:389-395[PMID:21207055 DOI:10.1007/s00423-010-0736-9]
25 Soejima Y,Shimada M,Suehiro T,Hiroshige S,Ninomiya M,Shiotani S,Harada N,Hideki I,Yonemura Y,Maehara Y.Outcome analysis in adult-to-adult living donor liver transplantation using the left lobe.Liver Transpl 2003;9:581-586[PMID:12783399DOI:10.1053/jlts.2003.50114]
26 Ben-Haim M,Emre S,Fishbein TM,Sheiner PA,Bodian CA,Kim-Schluger L,Schwartz ME,Miller CM.Critical graft size in adult-to-adult living donor liver transplantation:impact of the recipient’s disease.Liver Transpl 2001;7:948-953[PMID:11699030 DOI:10.1053/jlts.2001.29033]
27 Sudhindran S,Menon RN,Balakrishnan D.Challenges and Outcome of Left-lobe Liver Transplants in Adult Living Donor Liver Transplants.J Clin Exp Hepatol 2012;2:181-187[PMID:25755426 DOI:10.1016/S0973-6883(12)60106-6]
28 Yi NJ,Suh KS,Cho YB,Lee HW,Cho EH,Cho JY,Shin WY,Kim J,Lee KU.The right small-for-size graft results in better outcomes than the left small-for-size graft in adult-to-adult living donor liver transplantation.World J Surg 2008;32:1722-1730[PMID:18553047 DOI:10.1007/s00268-008-9641-6]
29 Soejima Y,Shirabe K,Taketomi A,Yoshizumi T,Uchiyama H,Ikegami T,Ninomiya M,Harada N,Ijichi H,Maehara Y.Left lobe living donor liver transplantation in adults.Am JTransplant 2012;12:1877-1885[PMID:22429497 DOI:10.1111/j.1600-6143.2012.04022.x]
30 Gruttadauria S,Pagano D,Liotta R,Tropea A,Tuzzolino F,Marrone G,Mamone G,Marsh JW,Miraglia R,Luca A,Vizzini G,Gridelli BG.Liver Volume Restoration and Hepatic Microarchitecture in Small-for-Size Syndrome.Ann Transplant2015;20:381-389[PMID:26148966 DOI:10.12659/AOT.894082]
31 Shoreem H,Gad EH,Soliman H,Hegazy O,Saleh S,Zakaria H,Ayoub E,Kamel Y,Abouelella K,Ibrahim T,Marawan I.Small for size syndrome difficult dilemma:Lessons from 10 years single centre experience in living donor liver transplantation.World JHepatol 2017;9:930-944[PMID:28824744 DOI:10.4254/wjh.v9.i21.930]
32 Lauro A,Diago Uso T,Quintini C,Di Benedetto F,Dazzi A,De Ruvo N,Masetti M,Cautero N,Risaliti A,Zanfi C,Ramacciato G,Begliomini B,Siniscalchi A,Miller CM,Pinna AD.Adult-to-adult living donor liver transplantation using left lobes:the importance of surgical modulations on portal graft inflow.Transplant Proc2007;39:1874-1876[PMID:17692638 DOI:10.1016/j.transproce ed.2007.05.052]
33 Kim DG,Moon IS,Kim SJ,Lee YJ,Lee MD.Effect of middle hepatic vein reconstruction in living donor liver transplantation using right lobe.Transplant Proc 2006;38:2099-2101[PMID:16980012 DOI:10.1016/j.transproceed.2006.06.005]
34 Peng CJ,Wang XF,Li B,Wei YG,Yan LN,Wen TF,Yang JY,Wang WT,Zhao JC.Efficacy of middle hepatic vein reconstruction in adult right-lobe living donor liver transplantation.Hepatobiliary Pancreat Dis Int 2010;9:135-138[PMID:20382582]
35 Wu H,Yan LN,Li B,Zeng Y,Wen TF,Zhao JC,Wang WT,Yang JY,Xu MQ,Chen ZY,Lu Q,Luo HZ,Li J.Hepatic venous outflow reconstruction in right lobe graft without middle hepatic vein.Hepatol Res 2007;37:1044-1051[PMID:17645520 DOI:10.1111/j.1872-034X.2007.00121.x]
36 Asakuma M,Fujimoto Y,Bourquain H,Uryuhara K,Hayashi M,Tanigawa N,Peitgen HO,Tanaka K.Graft selection algorithm based on congestion volume for adult living donor liver transplantation.Am J Transplant 2007;7:1788-1796[PMID:17524079 DOI:10.1111/j.1600-6143.2007.01849.x]
37 Navasa M,Feu F,García-Pagán JC,Jiménez W,Llach J,Rimola A,Bosch J,Rodés J.Hemodynamic and humoral changes after liver transplantation in patients with cirrhosis.Hepatology 1993;17:355-360[PMID:8444409]
38 Matsudaira S,Ishizaki Y,Yoshimoto J,Fujiwara N,Kawasaki S.Risk Factors for Intractable Ascites After Adult-to-Adult Living Donor Liver Transplantation Using Left Lobe.Transplant Direct 2017;3:e138[PMID:28361122 DOI:10.1097/TXD.0000000000000652]
39 Mukhtar A,Dabbous H.Modulation of splanchnic circulation:Role in perioperative management of liver transplant patients.World J Gastroenterol 2016;22:1582-1592[PMID:26819524DOI:10.3748/wjg.v22.i4.1582]
40 Kanetkar AV,Balakrishnan D,Sudhindran S,Dhar P,Gopalakrishnan U,Menon R,Sudheer OV.Is Portal Venous Pressure or Porto-systemic Gradient Really A Harbinger of Poor Outcomes After Living Donor Liver Transplantation?J Clin Exp Hepatol 2017;7:235-246[PMID:28970711 DOI:10.1016/j.jceh.2017.01.114]
41 Ikegami T,Shirabe K,Yoshizumi T,Aishima S,Taketomi YA,Soejima Y,Uchiyama H,Kayashima H,Toshima T,Maehara Y.Primary graft dysfunction after living donor liver transplantation is characterized by delayed functional hyperbilirubinemia.Am JTransplant 2012;12:1886-1897[PMID:22494784 DOI:10.1111/j.1600-6143.2012.04052.x]
42 Demetris AJ,Kelly DM,Eghtesad B,Fontes P,Wallis Marsh J,Tom K,Tan HP,Shaw-Stiffel T,Boig L,Novelli P,Planinsic R,Fung JJ,Marcos A.Pathophysiologic observations and histopathologic recognition of the portal hyperperfusion or smallfor-size syndrome.Am J Surg Pathol 2006;30:986-993[PMID:16861970]
43 Uemura T,Wada S,Kaido T,Mori A,Ogura Y,Yagi S,Fujimoto Y,Ogawa K,Hata K,Yoshizawa A,Okajima H,Uemoto S.How far can we lower graft-to-recipient weight ratio for living donor liver transplantation under modulation of portal venous pressure?Surgery 2016;159:1623-1630[PMID:26936527 DOI:10.1016/j.surg.2016.01.009]
44 Takahashi Y,Matsuura T,Yoshimaru K,Yanagi Y,Hayashida M,Taguchi T.Liver graft-to-spleen volume ratio as a useful predictive factor of the early graft function in children and young adults transplanted for biliary atresia:a retrospective study.Transpl Int2018;31:620-628[PMID:29424478 DOI:10.1111/tri.13131]
45 Karademir S,Astarcioglu H,Ozbilgin M,Ozkardesler S,Yilmaz T,Akarsu M,Akan M,Ozzeybek D,Obuz F,Astarcioglu I.Efficacy of right anterior sector drainage reconstruction in right-lobe livedonor transplantation.Transplant Proc 2006;38:3582-3584[PMID:17175337 DOI:10.1016/j.transproceed.2006.10.043]
46 Mori S,Park MS,Kim H,Choi Y,Hong G,Yi NJ,Lee KW,Suh KS.Dysfunction in Patients With Small-for-Size Grafts After Living Donor Liver Transplantation.Int Surg 2015;100:524-530[PMID:25785339 DOI:10.9738/INTSURG-D-14-00016.1]
47 Kim SH,Lee EC,Park SJ.Impact of preserved collateral veins on small-for-size grafts in living donor liver transplantation.Hepatol Res 2018;48:295-302[PMID:29125895 DOI:10.1111/hepr.13002]
48 Hessheimer AJ,Fondevila C,TauráP,Mu?oz J,Sánchez O,Fuster J,Rimola A,García-Valdecasas JC.Decompression of the portal bed and twice-baseline portal inflow are necessary for the functional recovery of a“small-for-size”graft.Ann Surg 2011;253:1201-1210[PMID:21587116 DOI:10.1097/SLA.0b013e3181ffb2d7]
49 Xiao L,Li F,Wei B,Li B,Tang CW.Small-for-size syndrome after living donor liver transplantation:successful treatment with a transjugular intrahepatic portosystemic shunt.Liver Transpl 2012;18:1118-1120[PMID:22511462 DOI:10.1002/lt.23457]
50 Sato Y,Oya H,Yamamoto S,Kobayashi T,Hara Y,Kokai H,Hatakeyama K.Method for spontaneous constriction and closure of portocaval shunt using a ligamentum teres hepatis in small-for-size graft liver transplantation.Transplantation 2010;90:1200-1203[PMID:21088651 DOI:10.1097/TP.0b013e3181fa93e0]
51 Nutu OA,Justo Alonso I,Marcacuzco Quinto AA,Calvo Pulido J,Jiménez Romero LC.Complete splenic embolization for the treatment of refractory ascites after liver transplantation.Rev Esp Enferm Dig 2018;110:257-259[PMID:29411988 DOI:10.17235/reed.2018.5338/2017]
52 Badawy A,Hamaguchi Y,Satoru S,Kaido T,Okajima H,Uemoto S.Evaluation of safety of concomitant splenectomy in living donor liver transplantation:a retrospective study.Transpl Int 2017;30:914-923[PMID:28512755 DOI:10.1111/tri.12985]
53 Troisi RI,Berardi G,Tomassini F,Sainz-Barriga M.Graft inflow modulation in adult-to-adult living donor liver transplantation:Asystematic review.Transplant Rev(Orlando)2017;31:127-135[PMID:27989547 DOI:10.1016/j.trre.2016.11.002]
54 Xu Y,Chen H,Yeh H,Wang H,Leng J,Dong J.Living donor liver transplantation using dual grafts:Experience and lessons learned from cases worldwide.Liver Transpl 2015;21:1438-1448[PMID:26336078 DOI:10.1002/lt.24315]
55 Gao W,Zhang L,Zhang Y,Sun C,Chen X,Wang Y.Adiposederived mesenchymal stem cells promote liver regeneration and suppress rejection in small-for-size liver allograft.Transpl Immunol2017;45:1-7[PMID:28778713 DOI:10.1016/j.trim.2017.07.005]
56 Kobayashi T,Sato Y,Yamamoto S,Oya H,Hara Y,Watanabe T,Kokai H,Hatakeyama K.Feasibility of auxiliary partial living donor liver transplantation for fulminant hepatic failure as an aid for small-for-size graft:single center experience.Transplant Proc2009;41:262-264[PMID:19249530 DOI:10.1016/j.transproceed.2008.10.025]
57 Dasari BVM,Schlegel A,Mergental H,Perera MTPR.The use of old donors in liver transplantation.Best Pract Res Clin Gastroenterol 2017;31:211-217[PMID:28624109 DOI:10.1016/j.bpg.2017.03.002]
58 Tanemura A,Mizuno S,Wada H,Yamada T,Nobori T,Isaji S.Donor age affects liver regeneration during early period in the graft liver and late period in the remnant liver after living donor liver transplantation.World J Surg 2012;36:1102-1111[PMID:22374540 DOI:10.1007/s00268-012-1496-1]
59 Abdelfattah MR,Elsiesy H.Reappraisal of upper age limit for adult living-donor liver transplantation using right lobe grafts:an outcome analysis.Eur J Gastroenterol Hepatol 2015;27:593-599[PMID:25822867 DOI:10.1097/MEG.0000000000000322]
60 Ono Y,Kawachi S,Hayashida T,Wakui M,Tanabe M,Itano O,Obara H,Shinoda M,Hibi T,Oshima G,Tani N,Mihara K,Kitagawa Y.The influence of donor age on liver regeneration and hepatic progenitor cell populations.Surgery 2011;150:154-161[PMID:21719061 DOI:10.1016/j.surg.2011.05.004]
61 Akamatsu N,Sugawara Y,Tamura S,Kaneko J,Matsui Y,Togashi J,Makuuchi M.Impact of live donor age on liver transplantation.Transplant Proc 2007;39:3189-3193[PMID:18089350 DOI:10.1016/j.transproceed.2007.03.116]
62 Kawano Y,Ishikawa N,Aida J,Sanada Y,Izumiyama-Shimomura N,Nakamura K,Poon SS,Matsumoto K,Mizuta K,Uchida E,Tajiri T,Kawarasaki H,Takubo K.Q-FISH measurement of hepatocyte telomere lengths in donor liver and graft after pediatric living-donor liver transplantation:donor age affects telomere length sustainability.PLo S One 2014;9:e93749[PMID:24727734DOI:10.1371/journal.pone.0093749]
63 Imamura H,Hidaka M,Soyama A,Kitasato A,Adachi T,Ono S,Natsuda K,Hara T,Kugiyama T,Baimakhanov Z,Okada S,Fujita F,Kanetaka K,Takatsuki M,Kuroki T,Eguchi S.A Donor AgeBased and Graft Volume-Based Analysis for Living Donor Liver Transplantation in Elderly Recipients.Transplant Direct 2017;3:e168[PMID:28706971 DOI:10.1097/TXD.0000000000000688]
64 Dayangac M,Taner CB,Yaprak O,Demirbas T,Balci D,Duran C,Yuzer Y,Tokat Y.Utilization of elderly donors in living donor liver transplantation:when more is less?Liver Transpl 2011;17:548-555[PMID:21506243 DOI:10.1002/lt.22276]
65 Yoshizumi T,Taketomi A,Uchiyama H,Harada N,Kayashima H,Yamashita Y,Soejima Y,Shimada M,Maehara Y.Graft size,donor age,and patient status are the indicators of early graft function after living donor liver transplantation.Liver Transpl 2008;14:1007-1013[PMID:18581462 DOI:10.1002/lt.21462]
66 Han JH,You YK,Na GH,Kim EY,Lee SH,Hong TH,Kim DG.Outcomes of living donor liver transplantation using elderly donors.Ann Surg Treat Res 2014;86:184-191[PMID:24783177DOI:10.4174/astr.2014.86.4.184]
67 Kamo N,Kaido T,Hammad A,Ogawa K,Fujimoto Y,Uemura T,Mori A,Hatano E,Okajima H,Uemoto S.Impact of elderly donors for liver transplantation:A single-center experience.Liver Transpl2015;21:591-598[PMID:25641778 DOI:10.1002/lt.24086]
68 Shin M,Moon HH,Kim JM,Park JB,Kwon CH,Kim SJ,Joh JW.Importance of donor-recipient age gradient to the prediction of graft outcome after living donor liver transplantation.Transplant Proc 2013;45:3005-3012[PMID:24157024 DOI:10.1016/j.trans proceed.2013.08.018]
69 Kubota T,Hata K,Sozu T,Ueda Y,Hirao H,Okamura Y,Tamaki I,Yoshikawa J,Kusakabe J,Tanaka H,Kageyama S,Anazawa T,Yoshizawa A,Yagi S,Yamashiki N,Okajima H,Kaido T,Uemoto S.Impact of Donor Age on Recipient Survival in Adult-to-Adult Living-donor Liver Transplantation.Ann Surg 2018;267:1126-1133[PMID:28288061 DOI:10.1097/SLA.0000000000002194]
70 Katsuragawa H,Yamamoto M,Katagiri S,Yoshitoshi K,Ariizumi S,Kotera Y,Takahashi Y,Takasaki K.Graft size and donor age are independent factors for graft loss in adult-to-adult living-donor liver transplantation using the left liver.J Hepatobiliary Pancreat Surg 2009;16:178-183[PMID:19165414 DOI:10.1007/s00534-008-0026-x]
71 Selzner N,Girgrah N,Lilly L,Guindi M,Selzner M,Therapondos G,Adeyi O,Mc Gilvray I,Cattral M,Greig PD,Grant D,Levy G,Renner EL.The difference in the fibrosis progression of recurrent hepatitis C after live donor liver transplantation versus deceased donor liver transplantation is attributable to the difference in donor age.Liver Transpl 2008;14:1778-1786[PMID:19025914 DOI:10.1002/lt.21598]
72 Wang K,Jiang WT,Deng YL,Pan C,Shen ZY.Effect of donor age on graft function and long-term survival of recipients undergoing living donor liver transplantation.Hepatobiliary Pancreat Dis Int2015;14:50-55[PMID:25655290]
73 Ikegami T,Taketomi A,Ohta R,Soejima Y,Yoshizumi T,Shimada M,Maehara Y.Donor age in living donor liver transplantation.Transplant Proc 2008;40:1471-1475[PMID:18589131 DOI:10.1016/j.transproceed.2008.02.084]
74 Li C,Wen TF,Yan LN,Li B,Yang JY,Xu MQ,Wang WT,Wei YG.Safety of living donor liver transplantation using older donors.J Surg Res 2012;178:982-987[PMID:22835951 DOI:10.1016/j.jss.2012.06.065]
75 Goldaracena N,Sapisochin G,Spetzler V,Echeverri J,Kaths M,Cattral MS,Greig PD,Lilly L,Mc Gilvray ID,Levy GA,Ghanekar A,Renner EL,Grant DR,Selzner M,Selzner N.Live Donor Liver Transplantation With Older(≥50 Years)Versus Younger Donors:Does Age Matter?Ann Surg 2016;263:979-985[PMID:26106842DOI:10.1097/SLA.0000000000001337]
76 Kim SH,Lee EC,Shim JR,Park SJ.Right lobe living donors ages55 years old and older in liver transplantation.Liver Transpl 2017;23:1305-1311[PMID:28734130 DOI:10.1002/lt.24823]
77 Starzl TE,Koep LJ,Halgrimson CG,Hood J,Schroter GP,Porter KA,Weil R 3rd.Fifteen years of clinical liver transplantation.Gastroenterology 1979;77:375-388[PMID:376395]
78 Sanchez-Urdazpal L,Sterioff S,Janes C,Schwerman L,Rosen C,Krom RA.Increased bile duct complications in ABO incompatible liver transplant recipients.Transplant Proc 1991;23:1440-1441[PMID:1989259]
79 Gugenheim J,Samuel D,Fabiani B,Saliba F,Castaing D,Reynes M,Bismuth H.Rejection of ABO incompatible liver allografts in man.Transplant Proc 1989;21:2223-2224[PMID:2652718]
80 Miyata R,Shimazu M,Tanabe M,Kawachi S,Hoshino K,Wakabayashi G,Kawai Y,Kitajima M.Clinical characteristics of thrombotic microangiopathy following ABO incompatible living donor liver transplantation.Liver Transpl 2007;13:1455-1462[PMID:17902122 DOI:10.1002/lt.21253]
81 Oya H,Sato Y,Yamamoto S,Nakatsuka H,Kobayashi T,Watanabe T,Kokai H,Hatakeyama K.Thrombotic microangiopathy after ABO-incompatible living donor liver transplantation:a case report.Transplant Proc 2008;40:2549-2551[PMID:18929797 DOI:10.1016/j.transproceed.2008.07.117]
82 Kishida N,Shinoda M,Itano O,Obara H,Kitago M,Hibi T,Yagi H,Abe Y,Matsubara K,Odaira M,Tanabe M,Shimazu M,Kitagawa Y.Increased Incidence of Thrombotic Microangiopathy After ABO-Incompatible Living Donor Liver Transplantation.Ann Transplant 2016;21:755-764[PMID:27956735]
83 Song GW,Lee SG,Hwang S,Kim KH,Ahn CS,Moon DB,Ha TY,Jung DH,Park GC,Kang SH,Jung BH,Yoon YI,Kim N.Biliary stricture is the only concern in ABO-incompatible adult living donor liver transplantation in the rituximab era.JHepatol 2014;61:575-582[PMID:24801413 DOI:10.1016/j.jhep.2014.04.039]
84 Ikegami T,Yoshizumi T,Soejima Y,Uchiyama H,Shirabe K,Maehara Y.Feasible usage of ABO incompatible grafts in living donor liver transplantation.Hepatobiliary Surg Nutr 2016;5:91-97[PMID:27115002 DOI:10.3978/j.issn.2304-3881.2015.06.02]
85 Sanchez-Urdazpal L,Batts KP,Gores GJ,Moore SB,Sterioff S,Wiesner RH,Krom RA.Increased bile duct complications in liver transplantation across the ABO barrier.Ann Surg 1993;218:152-158[PMID:8342994]
86 Demetris AJ,Jaffe R,Tzakis A,Ramsey G,Todo S,Belle S,Esquivel C,Shapiro R,Markus B,Mroczek E.Antibody-mediated rejection of human orthotopic liver allografts.A study of liver transplantation across ABO blood group barriers.Am J Pathol1988;132:489-502[PMID:3046369]
87 Choi SH,Kim KW,Kim SY,Kim JS,Kwon JH,Song GW,Lee SG.Computed tomography findings in ABO-incompatible living donor liver transplantation recipients with biliary strictures.Eur Radiol 2018;28:2572-2581[PMID:29294154 DOI:10.1007/s00330-017-5226-9]
88 Yamada Y,Hoshino K,Shimojima N,Shinoda M,Obara H,Kawachi S,Fuchimoto Y,Tanabe M,Kitagawa Y,Morikawa Y.Idiopathic hypereosinophilic syndrome in a case with ABO-incompatible liver transplantation for biliary atresia complicated by portal vein thrombosis.Pediatr Transplant 2010;14:e49-e53[PMID:20042017 DOI:10.1111/j.1399-3046.2009.01170.x]
89 Kawagishi N,Takeda I,Miyagi S,Satoh K,Akamatsu Y,Sekiguchi S,Satomi S.Long-term outcome of ABO-incompatible living-donor liver transplantation:a single-center experience.JHepatobiliary Pancreat Surg 2009;16:468-472[PMID:19333538DOI:10.1007/s00534-009-0074-x]
90 Yoon YI,Song GW,Lee SG,Hwang S,Kim KH,Kim SH,Kang WH,Cho HD,Jwa EK,Kwon JH,Tak EY,Kirchner VA.Outcome of ABO-incompatible adult living-donor liver transplantation for patients with hepatocellular carcinoma.J Hepatol 2018;68:1153-1162[PMID:29452208 DOI:10.1016/j.jhep.2018.02.002]
91 Sakai H,Tanaka Y,Tazawa H,Shimizu S,Verma S,Ohira M,Tahara H,Ide K,Ishiyama K,Kobayashi T,Onoe T,Ohdan H.Effect of Fc-γReceptor Polymorphism on Rituximab-Mediated B Cell Depletion in ABO-Incompatible Adult Living Donor Liver Transplantation.Transplant Direct 2017;3:e164[PMID:28620648 DOI:10.1097/TXD.0000000000000683]
92 Egawa H,Umeshita K,Uemoto S.Optimal dosage regimen for rituximab in ABO-incompatible living donor liver transplantation.J Hepatobiliary Pancreat Sci 2017;24:89-94[PMID:28002655DOI:10.1002/jhbp.419]
93 Ikegami T,Taketomi A,Soejima Y,Iguchi T,Sanefuji K,Kayashima H,Yoshizumi T,Harada N,Maehara Y.Successful ABO incompatible living donor liver transplantation in a patient with high isoagglutinin titer using high-dose intravenous immunoglobulin.Transplant Proc 2007;39:3491-3494[PMID:18089417 DOI:10.1016/j.transproceed.2007.09.028]
94 Ikegami T,Taketomi A,Soejima Y,Yoshizumi T,Uchiyama H,Harada N,Iguchi T,Hashimoto N,Maehara Y.Rituximab,IVIG,and plasma exchange without graft local infusion treatment:a new protocol in ABO incompatible living donor liver transplantation.Transplantation 2009;88:303-307[PMID:19667930 DOI:10.1097/TP.0b013e3181adcae6]
95 Usui M,Isaji S,Mizuno S,Sakurai H,Uemoto S.Experiences and problems pre-operative anti-CD20 monoclonal antibody infusion therapy with splenectomy and plasma exchange for ABO-incompatible living-donor liver transplantation.Clin Transplant 2007;21:24-31[PMID:17302588 DOI:10.1111/j.1399-0012.2006.00572.x]
96 Chen G,Sun J,Wei S,Chen Y,Tang G,Xie Z,Xu H,Chen J,Zhao H,Yuan Z,Wang W,Liu G,Wang B,Niu B.Simultaneous ABO-incompatible living-donor liver transplantation and splenectomy without plasma exchange in China:Two case reports.J Int Med Res 2017;45:2146-2152[PMID:28635356 DOI:10.1177/0300060517710407]
97 Uchiyama H,Mano Y,Taketomi A,Soejima Y,Yoshizumi T,Ikegami T,Shirabe K,Maehara Y.Kinetics of anti-blood type isoagglutinin titers and B lymphocytes in ABO-incompatible living donor liver transplantation with rituximab and plasma exchange.Transplantation 2011;92:1134-1139[PMID:21946174 DOI:10.1097/TP.0b013e318231e9f8]
98 Soin AS,Raut V,Mohanka R,Rastogi A,Goja S,Balachandran M,Saigal S,Saraf N,Bhangui P,Sumana KR,Singla P,Srinivasan T,Choudhary N,Tiwari A,Raina V,Govil D,Mohan N,Vohra V.Use of ABO-incompatible grafts in living donor liver transplantation--first report from India.Indian J Gastroenterol 2014;33:72-76[PMID:24369388 DOI:10.1007/s12664-013-0424-0]
99 Rummler S,Bauschke A,Baerthel E,Juette H,Maier K,Malessa C,Barz D,Settmacher U.ABO-Incompatible Living Donor Liver Transplantation in Focus of Antibody Rebound.Transfus Med Hemother 2017;44:46-51[PMID:28275333 DOI:10.1159/000450792]
100 Kim JD,Choi DL,Kim SG,Lee AJ.Single-Center Experience of ABO-Incompatible Living-Donor Liver Transplantation With a New Simplified Intravenous Immunoglobulin Protocol:APropensity Score-Matching Analysis.Transplant Proc 2016;48:1134-1138[PMID:27320573 DOI:10.1016/j.transproceed.2016.02.040]
101 Kim JM,Kwon CH,Joh JW,Kang ES,Park JB,Lee JH,Kim SJ,Paik SW,Lee SK,Kim DW.ABO-incompatible living donor liver transplantation is suitable in patients without ABO-matched donor.J Hepatol 2013;59:1215-1222[PMID:23928408 DOI:10.1016/j.jhep.2013.07.035]
102 Kawagishi N,Satoh K,Enomoto Y,Akamatsu Y,Sekiguchi S,Fukumori T,Fujimori K,Satomi S.New strategy for ABO-incompatible living donor liver transplantation with anti-CD20antibody(rituximab)and plasma exchange.Transplant Proc 2005;37:1205-1206[PMID:15848670 DOI:10.1016/j.transproceed.2004.12.114]
103 Kim SH,Lee EC,Shim JR,Park SJ.A simplified protocol using rituximab and immunoglobulin for ABO-incompatible low-titre living donor liver transplantation.Liver Int 2018;38:932-939[PMID:29053910 DOI:10.1111/liv.13614]
104 Yoshizawa A,Sakamoto S,Ogawa K,Kasahara M,Uryuhara K,Oike F,Ueda M,Takada Y,Egawa H,Tanaka K.New protocol of immunosuppression for liver transplantation across ABO barrier:the use of Rituximab,hepatic arterial infusion,and preservation of spleen.Transplant Proc 2005;37:1718-1719[PMID:15919443DOI:10.1016/j.transproceed.2005.03.148]
105 Egawa H,Teramukai S,Haga H,Tanabe M,Fukushima M,Shimazu M.Present status of ABO-incompatible living donor liver transplantation in Japan.Hepatology 2008;47:143-152[PMID:17929298 DOI:10.1002/hep.21928]
106 Yamamoto H,Uchida K,Kawabata S,Isono K,Miura K,Hayashida S,Oya Y,Sugawara Y,Inomata Y.Feasibility of Monotherapy by Rituximab Without Additional Desensitization in ABO-incompatible Living-Donor Liver Transplantation.Transplantation 2018;102:97-104[PMID:28938311 DOI:10.1097/TP.0000000000001956]
107 Jiménez-Castro MB,Negrete-Sánchez E,Casillas-Ramírez A,Gulfo J,álvarez-Mercado AI,Cornide-Petronio ME,GraciaSancho J,Rodés J,Peralta C.The effect of cortisol in rat steatotic and non-steatotic liver transplantation from brain-dead donors.Clin Sci(Lond)2017;131:733-746[PMID:28246131 DOI:10.1042/CS20160676]
108 Xue M,Lv C,Chen X,Liang J,Zhao C,Zhang Y,Huang X,Sun Q,Wang T,Gao J,Zhou J,Yu M,Fan J,Gao X.Donor liver steatosis:A risk factor for early new-onset diabetes after liver transplantation.J Diabetes Investig 2017;8:181-187[PMID:27511316 DOI:10.1111/jdi.12560]
109 Perkins JD.Saying“Yes”to obese living liver donors:short-term intensive treatment for donors with hepatic steatosis in livingdonor liver transplantation.Liver Transpl 2006;12:1012-1013[PMID:16721781 DOI:10.1002/lt.20807]
110 Kotecha HL,Saraf N,Saigal S,Choudhary NS,Yadav A,Mohanka R,Rastogi A,Menon PB,Goja S,Soin AS.NAFLDis the leading cause of donor rejection in living donor liver transplantation.J Clin Exp Hepatol 2013;3:S116[DOI:10.1016/j.jceh.2013.03.201]
111 Cho JY,Suh KS,Shin WY,Lee HW,Yi NJ,Kim MA,Jang JJ,Lee KU.Expansion of hepatic progenitor cell in fatty liver graft after living donor liver transplantation.Transpl Int 2010;23:530-537[PMID:20003044 DOI:10.1111/j.1432-2277.2009.01020.x]
112 Cho JY,Suh KS,Lee HW,Cho EH,Yang SH,Cho YB,Yi NJ,Kim MA,Jang JJ,Lee KU.Hepatic steatosis is associated with intrahepatic cholestasis and transient hyperbilirubinemia during regeneration after living donor liver transplantation.Transpl Int 2006;19:807-813[PMID:16961772 DOI:10.1111/j.1432-2277.2006.00355.x]
113 Cho JY,Suh KS,Kwon CH,Yi NJ,Cho SY,Jang JJ,Kim SH,Lee KU.The hepatic regeneration power of mild steatotic grafts is not impaired in living-donor liver transplantation.Liver Transpl 2005;11:210-217[PMID:15666394 DOI:10.1002/lt.20340]
114 Gao F,Xu X,Ling Q,Wu J,Zhou L,Xie HY,Wang HP,Zheng SS.Efficacy and safety of moderately steatotic donor liver in transplantation.Hepatobiliary Pancreat Dis Int 2009;8:29-33[PMID:19208511]
115 Knaak M,Goldaracena N,Doyle A,Cattral MS,Greig PD,Lilly L,Mc Gilvray ID,Levy GA,Ghanekar A,Renner EL,Grant DR,Selzner M,Selzner N.Donor BMI;30 Is Not a Contraindication for Live Liver Donation.Am J Transplant 2017;17:754-760[PMID:27545327 DOI:10.1111/ajt.14019]
116 Han S,Ha SY,Park CK,Joh JW,Kwon CH,Kwon GY,Kim G,Gwak MS,Jeong WK,Ko JS.Microsteatosis may not interact with macrosteatosis in living donor liver transplantation.JHepatol 2015;62:556-562[PMID:25450710 DOI:10.1016/j.jhep.2014.10.027]
117 Oshita A,Tashiro H,Amano H,Kobayashi T,Onoe T,Ide K,Takaki S,Takahashi S,Arihiro K,Chayama K,Ohdan H.Safety and feasibility of diet-treated donors with steatotic livers at the initial consultation for living-donor liver transplantation.Transplantation 2012;93:1024-1030[PMID:22495493 DOI:10.1097/TP.0b013e31824c9e25]
118 Nakamuta M,Morizono S,Soejima Y,Yoshizumi T,Aishima S,Takasugi S,Yoshimitsu K,Enjoji M,Kotoh K,Taketomi A,Uchiyama H,Shimada M,Nawata H,Maehara Y.Short-term intensive treatment for donors with hepatic steatosis in livingdonor liver transplantation.Transplantation 2005;80:608-612[PMID:16177634]
119 Choudhary NS,Saraf N,Saigal S,Gautam D,Lipi L,Rastogi A,Goja S,Menon PB,Bhangui P,Ramchandra SK,Soin AS.Rapid Reversal of Liver Steatosis With Life Style Modification in Highly Motivated Liver Donors.J Clin Exp Hepatol 2015;5:123-126[PMID:26155039 DOI:10.1016/j.jceh.2015.04.002]
120 Moon D,Lee S,Hwang S,Kim K,Ahn C,Park K,Ha T,Song G.Resolution of severe graft steatosis following dual-graft living donor liver transplantation.Liver Transpl 2006;12:1156-1160[PMID:16799937 DOI:10.1002/lt.20814]
121 Wang SH,Loh PY,Lin TL,Lin LM,Li WF,Lin YH,Lin CC,Chen CL.Active immunization for prevention of De novo hepatitis B virus infection after adult living donor liver transplantation with a hepatitis B core antigen-positive graft.Liver Transpl 2017;23:1266-1272[PMID:28691231 DOI:10.1002/lt.24814]
122 Xi ZF,Xia Q,Zhang JJ,Chen XS,Han LZ,Zhu JJ,Wang SY,Qiu DK.De novo hepatitis B virus infection from anti-HBcpositive donors in pediatric living donor liver transplantation.J DigDis 2013;14:439-445[PMI D:23638710DOI:10.1111/1751-2980.12066]
123 Dong C,Gao W,Ma N,Sun C,Zheng WP,Wang K,Shen ZY.Risks and treatment strategies for de novo hepatitis B virus infection from anti-HBc-positive donors in pediatric living donor liver transplantation.Pediatr Transplant 2017;21[PMID:27933716 DOI:10.1111/petr.12854]
124 Loggi E,Conti F,Cucchetti A,Ercolani G,Pinna AD,Andreone P.Liver grafts from hepatitis B surface antigen-positive donors:A review of the literature.World J Gastroenterol 2016;22:8010-8016[PMID:27672295 DOI:10.3748/wjg.v22.i35.8010]
125 Lei J,Yan L,Wang W.A comprehensive study of the safety of using anti-hepatitis B core(Hbc)positive subjects in living donor liver transplants.Hepatogastroenterology 2013;60:1426-1432[PMID:23933935 DOI:10.5754/hge13062]
126 Lin CC,Chen CL,Concejero A,Wang CC,Wang SH,Liu YW,Yang CH,Yong CC,Lin TS,Jawan B,Cheng YF,Eng HL.Active immunization to prevent de novo hepatitis B virus infection in pediatric live donor liver recipients.Am J Transplant 2007;7:195-200[PMID:17227568 DOI:10.1111/j.1600-6143.2006.01618.x]
127 Hara Y,Tokodai K,Nakanishi C,Miyagi S,Kawagishi N.Spontaneous resolution of de novo hepatitis B after living donor liver transplantation with hepatitis B core antibody positive graft:a case report.Surg Case Rep 2016;2:118[PMID:27797067 DOI:10.1186/s40792-016-0246-2]
128 Sasaki R,Kanda T,Ohtsuka M,Yasui S,Haga Y,Nakamura M,Yokoyama M,Wu S,Nakamoto S,Arai M,Maruyama H,Miyazaki M,Yokosuka O.Successful Management of Graft Reinfection of HCV Genotype 2 in Living Donor Liver Transplantation from a Hepatitis B Core Antibody-Positive Donor with Sofosbuvir and Ribavirin.Case Rep Gastroenterol 2016;10:366-372[PMID:27721720 DOI:10.1159/000447423]
129 Hwang S,Lee SG,Park KM,Kim KH,Ahn CS,Oh HB,Moon DB,Ha TY,Lim YS,Jung DH.Five-year follow-up of a hepatitis B virus-positive recipient of hepatitis B surface antigen-positive living donor liver graft.Liver Transpl 2006;12:993-997[PMID:16721765 DOI:10.1002/lt.20799]
130 Soejima Y,Shimada M,Taketomi A,Yoshizumi T,Uchiyama H,Ikegami T,Nakamuta M,Maehara Y.Successful living donor liver transplantation using a graft from a hepatitis B surface antigenpositive donor.Liver Int 2007;27:1282-1286[PMID:17919241DOI:10.1111/j.1478-3231.2007.01528.x]
131 Jeng LB,Thorat A,Yang HR,Yeh CC,Chen TH,Hsu CH,Hsu SC,Poon KS,Li PC,Lai HC,Su WP,Peng CY.Successful use of hepatitis B surface antigen-positive liver grafts-an effective source for donor organs in endemic areas:a single-center experience.Ann Transplant 2015;20:103-111[PMID:25703063 DOI:10.12659/AOT.893032]
132 Tang Z,Li X,Wu S,Liu Y,Qiao Y,Xu D,Li J.Risk of hepatitis B reactivation in HBs Ag-negative/HBc Ab-positive patients with undetectable serum HBV DNA after treatment with rituximab for lymphoma:a meta-analysis.Hepatol Int 2017;11:429-433[PMID:28856548 DOI:10.1007/s12072-017-9817-y]
133 Li G,Mu X,Huang X,Qian X,Qin J,Tan Z,Zhang W,Xu X,Tan S,Zhu Z,Li W,Wang X,Wang X,Sun B.Liver transplantation using the otherwise-discarded partial liver resection graft with hepatic benign tumor:Analysis of a preliminary experience on 15consecutive cases.Medicine(Baltimore)2017;96:e7295[PMID:28723742 DOI:10.1097/MD.0000000000007295]
134 Fuchino M,Tajiri K,Minemura M,Sugiyama T.Vanishing Tumor in a Liver Graft from a Hepatitis B Virus Surface AntigenPositive Donor.Case Rep Gastroenterol 2017;11:610-615[PMID:29118691 DOI:10.1159/000481164]