杯三嗪固定相桥连氮原子上引入苄基对分离选择性的影响
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摘要
<正>基于固定相结构上小的改变会导致色谱分离的显著变化,实验将大环杯三嗪的桥连氮原子上引入苄基后[1],利用键合手段,成功制备了一种四苄基氮氮桥连杯[2]芳烃[2]三嗪键合硅胶液相色谱固定相(Bz NCS),并以我们实验室前期合成的四氮杂杯[2]芳烃[2]三嗪键合硅胶固定相(NCS)[2]作参比,以多种溶质为探针,评价了新固定相的色谱性能,并在相同的色谱条件下进行了对比研究,较深入地探讨了分离机理和配体结构对色谱性能的影响,色谱分析数据结果表明,苄基的引入改变
引文
1.Q.Wang,D.Wang,H.Ma,M.Wang,Synthesis of Tetraazacalix[2]arene[2]-triazines:Tuning the Cavity by the Substituents on the Bridging Nitrogen Atoms,Org.lett.,2006,8:5967-5970
2.M.Wang,H.Yang,A general and high yielding fragment coupling synthesis of heteroatom-bridged calixarenes and the unprecedented examples of calixarene cavity fine-tuned by bridging heteroatoms,J.Am.Chem.Soc.,2004,126:15412-15422
2.M.Wang,H.Yang,A general and high yielding fragment coupling synthesis of heteroatom-bridged calixarenes and the unprecedented examples of calixarene cavity fine-tuned by bridging heteroatoms,J.Am.Chem.Soc.,2004,126:15412-15422