非均相体系荧光化学/生物传感技术中的化学计量学理论及应用研究
详细信息 查看官网全文
- 英文论文题名：Chemomstric theory and applications to fluorescence-based chemo/bio sensing technologies for heterogeneous systems
- 论文作者：陈增萍
- 英文论文作者：Z.P.Chen ; State Key Laboratory of Chemo/Biosensing and Chemometrics ; College of Chemistry and Chemical Engineering ; Hunan University
- 年：2016
- 作者机构：湖南大学化学化工学院化学生物传感与计量学国家重点实验室;
- 论文关键词：非均相体系 ; 荧光化学/生物传感技术 ; 化学计量学
- 会议召开时间：2016-07-01
- 会议录名称：中国化学会第30届学术年会摘要集-第二十五分会：化学信息学与化学计量学
- 语种：中文
- 分类号：O657.3
- 学会代码：ZGHY
- 会议名称：中国化学会第30届学术年会-第二十五分会 ; 化学信息学与化学计量学
- 会议地点：中国辽宁大连
- 主办单位：中国化学会
- 学会名称：中国化学会
- 页数：1
- 文件大小：103k
- 原文格式：D
- 会议级别：全国
摘要
由于非均相体系中存在的散射物质的散射效应和吸光物质的吸收效应严重影响待测荧光物质荧光光谱信号的形状和强度,使得现有的荧光化学/生物传感理论和技术不适用于非均相体系的定量分析。本研究小组针对非均相体系荧光/化学生物传感定量分析中存在的问题进行了系统的研究和探索【1-3】。本文在总结已取得的成果的基础上,提出了非均相体系荧光传感定量分析理论和模型,并在该理论的指导下设计出了多个新型荧光化学/生物传感器,实现了多个复杂非均相体系中待测物质的准确定量分析。
The presence of practically unavoidable scatterers and background absorbers in turbid media such as biological tissue or cell suspensions can significantly distort the shape and intensity of fluorescence spectra of fluorophores,and hence greatly hinder the application of fluorescence-based chem/bio sensing technologies to the quantitative analysis of turbid media.Our research group has devoted great effort to chemomstric theory for quantitative analysis of heterogeneous systems using fluorescence-based chemo/bio sensing technologies and made some achievements.In this contribution,we discussed in detail the theory of an advanced quantitative fluorescence model for heterogeneous systems drawn from our previous achievements,and the application of several fluorescence-based chem/bio sensors designed under the guidance of the new model.
The presence of practically unavoidable scatterers and background absorbers in turbid media such as biological tissue or cell suspensions can significantly distort the shape and intensity of fluorescence spectra of fluorophores,and hence greatly hinder the application of fluorescence-based chem/bio sensing technologies to the quantitative analysis of turbid media.Our research group has devoted great effort to chemomstric theory for quantitative analysis of heterogeneous systems using fluorescence-based chemo/bio sensing technologies and made some achievements.In this contribution,we discussed in detail the theory of an advanced quantitative fluorescence model for heterogeneous systems drawn from our previous achievements,and the application of several fluorescence-based chem/bio sensors designed under the guidance of the new model.
引文
[1]Kong,J.;Chen,Z.;Chen,Y.;Yan,X.;Yu,R.Chemom.Intell.Lab.Syst.2016,151:9.
[2]Yan,X.;Chen,Z.;Kong,J.;Hu,Y.;Chen,Y.;Yu,R.Chemom.Intell.Lab.Syst.2015,147:41.
[3]Chen,Y;Chen,Z.;Yang J.;Jin,J.;Zhang,J.;Yu,R.Anal.Chem.2013,85:2015.
[2]Yan,X.;Chen,Z.;Kong,J.;Hu,Y.;Chen,Y.;Yu,R.Chemom.Intell.Lab.Syst.2015,147:41.
[3]Chen,Y;Chen,Z.;Yang J.;Jin,J.;Zhang,J.;Yu,R.Anal.Chem.2013,85:2015.