短暂性脑缺血发作及脑梗死患者血清尿酸水平的变化及其临床意义
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- 论文作者：邢戈贝莉 ; 李自如 ; 韩冰
- 年：2016
- 作者机构：内蒙古自治区人民医院;
- 论文关键词：短暂性脑缺血发作 ; 脑梗死 ; 高尿酸血症
- 英文论文关键词：transient ischemic attack ; Cerebral infarction ; High uric acid hematic disease
- 会议召开时间：2016-11-25
- 会议录名称：湖南中医药大学学报2016/专集：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会论文集
- 语种：中文
- 分类号：R743.3
- 学会代码：HNZY
- 会议名称：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会
- 会议地点：中国广东珠海
- 主办单位：国际数字医学会、Digital Chinese Medicine
- 学会名称：湖南中医药大学期刊杂志社
- 页数：2
- 文件大小：1859k
- 原文格式：D
- 会议级别：全国
摘要
目的分析短暂性脑缺血发作(TIA)及脑梗死患者血清尿酸水平的变化,探讨高尿酸血症对缺血性脑血管病病情及预后的影响。方法将40例临床诊断TIA首次发作患者作为TIA组,40例临床诊断脑梗死患者作为脑梗死组,40例健康体检患者作为对照组,采用尿酸酶法检测各组血清尿酸含量,分析其水平变化并进行相关性研究。结果三组研究对象血清尿酸水平差异均具有统计学意义(p<0.05),TIA组、脑梗死组血清尿酸水平均高于健康对照组(P<0.01),脑梗死组血清尿酸水平高于TIA组(P<0.01)。结论高尿酸血症可加重缺血性脑血管病的病情,是TIA及脑梗死的预后不良因素,血清尿酸水平的临床监测,可为TIA及脑梗死患者的病情判断提供信息。
objective to analyze transient ischemic attack(TIA) and cerebral infarction patients with serum uric acid level changes, discusses high uric acid hematic disease impact onillness and prognosis of ischemic cerebrovascular disease. Methods 40 patients with the first clinical diagnosis of TIA as TIA group, 40 cases of clinical diagnosis of cerebral infarction patientsas cerebral infarction group, 40 cases of healthy check-up patients as control group, the uric acid enzymatic test groups of serum uric acid levels, analyzes the level change and correlation studies. Results three groups of serum uric acid level differences were statistically significant(p < 0.05), serum uric acid level TIA group, the cerebral infarction group were higher than that of healthycontrols(p < 0.01), cerebral infarction group serum uric acid level higher than the TIA group(p < 0.01). Conclusion high uric acid hematic disease can increase ? ischemic cerebrovasculardisease
objective to analyze transient ischemic attack(TIA) and cerebral infarction patients with serum uric acid level changes, discusses high uric acid hematic disease impact onillness and prognosis of ischemic cerebrovascular disease. Methods 40 patients with the first clinical diagnosis of TIA as TIA group, 40 cases of clinical diagnosis of cerebral infarction patientsas cerebral infarction group, 40 cases of healthy check-up patients as control group, the uric acid enzymatic test groups of serum uric acid levels, analyzes the level change and correlation studies. Results three groups of serum uric acid level differences were statistically significant(p < 0.05), serum uric acid level TIA group, the cerebral infarction group were higher than that of healthycontrols(p < 0.01), cerebral infarction group serum uric acid level higher than the TIA group(p < 0.01). Conclusion high uric acid hematic disease can increase ? ischemic cerebrovasculardisease
引文
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[2]LEHTO S,NISKANENIL,RONNEMAAT,et al.Serum aric acid is a strong predictor of stroke in patients with non-insution-dependen diabetes mellitus[J].Stroke,1998,29(3):635-639.
[3]全国第四届脑血管病诊断标准学术会议.脑血管疾病分类[J].中华神经科杂志,1996,29(6):376-381.
[4]中华神经科学会.各类脑血管病诊断要点[J].中华神经科杂志,1996,29(6):379-80.
[5]王志红,刘宏顺,张祥建,等.短暂性脑缺血发作患者短期内发生脑梗死危险因素分析[J].脑与神经系统疾病杂志,2010,18:458-461.
[6]赵素霞,杨云峰,王健.急性脑梗死患者血尿酸水平与预后的相关分析[J].脑与神经疾病杂志,2008,16(4):509-10.
[7]丘朝晖,曹奕.高尿酸血症与高血压的关系.国外医学,心血管分册,2001,28(1)9-11.
[8]颜海燕,周兰兰.尿酸生物功能及研究进展[J].安徽医药,2007,11(9):769-71.
[9]Weir CJ,Muir SW,walters MR,et al Serumurate as an independent predictor of pool outcome and future vascular events after acute stroke Stroke,2003,34(8):1951-1957.
[10]易卫平,荣举,林小荣,等.急性缺血性脑卒中患者入院时血尿酸水平与预后分析.中国医师进修杂志,2006,29(7):41-42.