双靶向多肽探针的构建及其与蛋白质的协同相互作用研究
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摘要
<正>特异性靶向分子探针是复杂体系分离分析的有力工具。在备受关注的生命体系,环境体系及药物体系等的分析中,基于分子识别的理论及原理,构建高亲和力、高选择性的分子探针,发展新的分析、检测方法和技术,已成为研究的热点与前沿。多肽作为蛋白质的组成成分,是重要的生理活性物质。相较于生物大分子探针,多肽具有分子量小、生物相容性好,穿透性强,性质稳定,免疫原性低等特点,在生命分析等领域具有广阔的应用前景。协同作用广泛存在于具有多个亚基的酶、受体蛋白与其配体的结合过程之中。基于协同作用这
引文
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