康复工疗对慢性精神分裂症患者阴性症状、认知功能和社会功能的影响
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- 英文论文题名：Effects of work therapy on negative symptoms,cognitive function and social function of chronic schizophrenia
- 论文作者：陈远岭 ; 温亚平 ; 刘家洪 ; 黄文武
- 英文论文作者：Chen Yuanling ; Wen Yaping ; Liu Jiahong ; Huang Wenwu ; Department of Psychiatric ; Wenzhou Kangning Hospital
- 年：2014
- 作者机构：温州康宁医院;
- 论文关键词：精神分裂症 ; 康复工疗 ; 认知功能 ; 社会功能
- 英文论文关键词：Schizophrenia ; Work therapy ; Cognitive function ; Social function
- 会议召开时间：2014-11-20
- 会议录名称：2014浙江省医学会精神病学分会学术年会、浙江省医师协会精神科医师分会第七届年会论文汇编
- 语种：中文
- 分类号：R749.3
- 学会代码：ZJKX
- 会议名称：2014浙江省医学会精神病学分会学术年会、浙江省医师协会精神科医师分会第七届年会
- 会议地点：中国浙江湖州
- 主办单位：浙江省医学会精神病学分会（The Society of Psychiatry ; ZJMA）、浙江省医师协会精神科医师分会
- 学会名称：浙江省科学技术协会
- 页数：5
- 文件大小：424k
- 原文格式：O
- 会议级别：地方
摘要
目的了解药物结合康复工疗对慢性精神分裂症患者阴性症状、认知功能和社会功能改善的作用。方法将温州康宁医院精神科病房的300例慢性精神分裂症患者随机分为研究组(药物治疗结合康复工疗)和对照组(药物治疗),每组各150例。患者在入组时、入组后12周及随访半年时应用阴性症状量表(SANS)、韦氏成人智力测验(WAIS)、个人和社会功能量表(PSP)进行评估。康复工疗前后计量资料采用配对样本t检验进行统计;组间计量资料采用独立样本t检验;计数资料应用卡方检验,随访资料采用重复测量的方差分析。结果(1)治疗12周及随访半年时,研究组SANS总分与入组时比较差异有统计学意义(t=7.74,F=11.32,均P<0.01);对照组SANS差异无统计学意义(均P>0.05)。研究组和对照组SANS评分的组间比较:入组时评分比较无明显差异(t=1.76,P>0.05);二组具有可比性;治疗12周及随访半年时二组比较有显著差异(t=6.76,t=8.12,均P<0.01)。(2)治疗12周及随访半年时,研究组WAIS总分增加,认知功能改善,差异有统计学意义(t=5.31,P<0.05;F=8.17,P<0.01)。对照组WAIS总分增加不明显,差异无统计学意义(均P>0.05)。二组的组间比较:入组时二组WAIS评分比较无明显差异(t=2.05,P>0.05),二组具有可比性;治疗12周及随访半年时二组比较有显著差异(t=3.87,t=5.23,均P<0.05)。(3)经过12周的康复工疗,在入组后12周及随访半年时,研究组PSP总分增加,社会功能改善,差异有统计学意义(t=4.81,P<0.05;F=10.54,P<0.01)。对照组PSP总分增加不明显,差异无统计学意义(均P>0.05)。二组的组间比较:入组时二组PSP评分比较无明显差异(t=1.24,P>0.05);治疗12周及随访半年时二组比较有显著差异(t=5.37,P<0.05;t=9.36,P<0.01)。结论药物治疗结合康复工疗的模式可使慢性精神分裂症患者的阴性症状减少,认知功能和社会功能较治疗前提高。
Objective To be aware of the medicine withwork therapy s influence to chronic schizophrenia s negative syndrome,cognitive function and social function.Methods Three hundred cases of chronic schizophrenia of Wenzhou Kangning Hospital were divided into two groups:study group(medicine with work therapy) and control group(medicine).There were 150 cases in each group.The scale assessment of negative syndrome(SANS),Wechscler adult intelligence scale(WAIS) and personal and social performance scale(PSP) were tested at the beginning,12 weeks later and half year after follow up.The differences of the two groups were compared by paired samples t test,independent sample t test or chi-square test,follow-up data between the two groups were compared by repeated measures analysis of variance.Results(1) After treatment for 12 weeks and half year after follow up,there were stastical significance of SANS total scores in work therapy group compared with the beginning(t=7.74,F=11.32,all P < 0.01);no work therapy group,SANS total scores compared with at the beginning have no obvious conspicuousness(all P >0.05).The scores of SANS shown no difference between two gropes before treatmemt(t=1.76,P > 0.05).The scores of SANS had significant difference between study group and control group after treatment for 12 weeks and half year after follow up(t=6.76,t=8.12,all P < 0.01).(2) After treatment for 12 weeks and half year after follow up,WAIS total scores increased,cognitive function was improved in work therapy group,there were stastical significance between the two groups(t=5.31,P < 0.05;F=8.17,P<0.01).The increasing of WAIS total scores was not obvious in control group,there was no stastical significance between the two groups(all P >0.05).The scores of WAIS shown no difference between two gropes before treatmemt(t=2.05,P > 0.05).The scores of WAIS had significant difference between study group and control group after treatment for12 weeks and half year after follow up(t=3.87,t=5.23,all P < 0.05).(3) After treatment for 12 weeks and half year after follow up,The treatment effect of social function,work therapy group PSP total scores increase,social function improve,very obvious difference has conspicuousness(t=4.81,P < 0.05;F=10.54;P <0.01).control group PSP total scores increase not obvious,difference has no conspicuousness(all P >0.05).The scores of PSP shown no difference between two gropes before treatmemt(t=1.24,P > 0.05).The scores of PSP had significant difference between study group and control group after treatment for 12 weeks and half year after follow up(t=5.37,P < 0.05;t=9.36,P < 0.01).Conclusion:Medicine with work therapy can make chronic schizophrenia patient s negative symptoms cut down,cognitive function and social function enhance compared with before treatment.
Objective To be aware of the medicine withwork therapy s influence to chronic schizophrenia s negative syndrome,cognitive function and social function.Methods Three hundred cases of chronic schizophrenia of Wenzhou Kangning Hospital were divided into two groups:study group(medicine with work therapy) and control group(medicine).There were 150 cases in each group.The scale assessment of negative syndrome(SANS),Wechscler adult intelligence scale(WAIS) and personal and social performance scale(PSP) were tested at the beginning,12 weeks later and half year after follow up.The differences of the two groups were compared by paired samples t test,independent sample t test or chi-square test,follow-up data between the two groups were compared by repeated measures analysis of variance.Results(1) After treatment for 12 weeks and half year after follow up,there were stastical significance of SANS total scores in work therapy group compared with the beginning(t=7.74,F=11.32,all P < 0.01);no work therapy group,SANS total scores compared with at the beginning have no obvious conspicuousness(all P >0.05).The scores of SANS shown no difference between two gropes before treatmemt(t=1.76,P > 0.05).The scores of SANS had significant difference between study group and control group after treatment for 12 weeks and half year after follow up(t=6.76,t=8.12,all P < 0.01).(2) After treatment for 12 weeks and half year after follow up,WAIS total scores increased,cognitive function was improved in work therapy group,there were stastical significance between the two groups(t=5.31,P < 0.05;F=8.17,P<0.01).The increasing of WAIS total scores was not obvious in control group,there was no stastical significance between the two groups(all P >0.05).The scores of WAIS shown no difference between two gropes before treatmemt(t=2.05,P > 0.05).The scores of WAIS had significant difference between study group and control group after treatment for12 weeks and half year after follow up(t=3.87,t=5.23,all P < 0.05).(3) After treatment for 12 weeks and half year after follow up,The treatment effect of social function,work therapy group PSP total scores increase,social function improve,very obvious difference has conspicuousness(t=4.81,P < 0.05;F=10.54;P <0.01).control group PSP total scores increase not obvious,difference has no conspicuousness(all P >0.05).The scores of PSP shown no difference between two gropes before treatmemt(t=1.24,P > 0.05).The scores of PSP had significant difference between study group and control group after treatment for 12 weeks and half year after follow up(t=5.37,P < 0.05;t=9.36,P < 0.01).Conclusion:Medicine with work therapy can make chronic schizophrenia patient s negative symptoms cut down,cognitive function and social function enhance compared with before treatment.
引文
[1].崔承英,谷广匠,胡佰,等.精神分裂症患者社会危害及致残率研究[J].临床精神医学杂志,2000,10(4):214-215.
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[3].Corcoral CM,Kimhy D,Parrilla-Escobar MA,et al.The relationship of social function to depression and negative symptoms in individuals at clinical high risk for psychosis[J].Psychol Med,2011,41(3):251-261
[4].张明圆,主编.精神科评定量表[M].2版.长沙:湖南科学技术出版社,1998:151-154,163-166.
[5].Nasrallah H,Morosini P,Gagnon DD.Reliability,validity and ability to detect change of the personal and social performance scale in patients with stable schizophrenia[J].Psychiatry Res,2008,161(5):213-224
[6].赵晶媛,张红星,郭素芹.社会心理综合干预对精神分裂症患者康复的影响[J].中国康复医学杂志,2009,24(5):448-450.
[7].崔宏维,魏丽霞,刘传军.药物治疗与药物合并集中康复治疗精神分裂症患者的生活质量对照研究[J].中国民康医学,2009,21(11):1315-1316.
[8].陈平,赵虎,刘凤翔.精神病康复防治网络对男性复员退伍军人精神分裂症患者管理及康复效果的影响[J].四川精神卫生,2014,27(1):68-69.
[9].张秀丽,杨秀双,王伟业,等.个案管理对重性精神病患者健康状况和生活质量的影响[J].中国民康医学,2013,25(23):2256-2258.
[10].Kooyman I,Dean K,Harvey S,et al.Outcome of public concern in schizophrenia[J].Br J Psychiatry,2007,50(1):29-36.
[11].Kurzban S,Davis L,Brekke JS.Vocational,social,and cognitive rehabilitation for individuals diagnosed with schizophrenia[J].Curr Psychiatry Rep,2010,12(6):345-355.
[12].Bio DS,Gattaz WF.Vocational rehabilitation improves cognition and negative symptoms in schizophrenia[J].Schizophr Res,2011,126(3):265-269.
[2].Raffard S,Gely-Nargeot MC,Capdevielle D,et al.Learning potential and cognitive remediation in schizophrenia[J].Encephale,2009,35(5):353-360
[3].Corcoral CM,Kimhy D,Parrilla-Escobar MA,et al.The relationship of social function to depression and negative symptoms in individuals at clinical high risk for psychosis[J].Psychol Med,2011,41(3):251-261
[4].张明圆,主编.精神科评定量表[M].2版.长沙:湖南科学技术出版社,1998:151-154,163-166.
[5].Nasrallah H,Morosini P,Gagnon DD.Reliability,validity and ability to detect change of the personal and social performance scale in patients with stable schizophrenia[J].Psychiatry Res,2008,161(5):213-224
[6].赵晶媛,张红星,郭素芹.社会心理综合干预对精神分裂症患者康复的影响[J].中国康复医学杂志,2009,24(5):448-450.
[7].崔宏维,魏丽霞,刘传军.药物治疗与药物合并集中康复治疗精神分裂症患者的生活质量对照研究[J].中国民康医学,2009,21(11):1315-1316.
[8].陈平,赵虎,刘凤翔.精神病康复防治网络对男性复员退伍军人精神分裂症患者管理及康复效果的影响[J].四川精神卫生,2014,27(1):68-69.
[9].张秀丽,杨秀双,王伟业,等.个案管理对重性精神病患者健康状况和生活质量的影响[J].中国民康医学,2013,25(23):2256-2258.
[10].Kooyman I,Dean K,Harvey S,et al.Outcome of public concern in schizophrenia[J].Br J Psychiatry,2007,50(1):29-36.
[11].Kurzban S,Davis L,Brekke JS.Vocational,social,and cognitive rehabilitation for individuals diagnosed with schizophrenia[J].Curr Psychiatry Rep,2010,12(6):345-355.
[12].Bio DS,Gattaz WF.Vocational rehabilitation improves cognition and negative symptoms in schizophrenia[J].Schizophr Res,2011,126(3):265-269.