H型高血压和微量蛋白尿的关系
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- 论文作者：李健
- 年：2016
- 作者机构：南京鼓楼医院集团仪征医院;
- 论文关键词：H型高血压 ; 微量蛋白尿 ; 相关性
- 英文论文关键词：H type hypertension ; trace protein urine ; correlation
- 会议召开时间：2016-11-25
- 会议录名称：湖南中医药大学学报2016/专集：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会论文集
- 语种：中文
- 分类号：R544.1;R696.2
- 学会代码：HNZY
- 会议名称：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会
- 会议地点：中国广东珠海
- 主办单位：国际数字医学会、Digital Chinese Medicine
- 学会名称：湖南中医药大学期刊杂志社
- 页数：2
- 文件大小：2038k
- 原文格式：D
- 会议级别：全国
摘要
目的探讨H型高血压与微量蛋白尿相关性。方法选取2014年4月~2015年10月我院收治H型高血压患者120例为作为研究组,按照血压水平分为1级、2级和3级高血压组,选取同期我院体检中心体检健康自愿者50名作为对照组,采用免疫散射比浊法检测患者微量蛋白尿,分别比较研究组和对照组,研究组不同分级高血压患者中微量蛋白尿。结果研究组患者微量蛋白尿水平显著高于对照组,比较有统计学意义(P<0.05)。按照高血压分级标准,120例H型高血压患者分为1级42例,2级53例,3级25例。随着高血压分级升高,微量蛋白尿水平随之升高,组间各值相互比较有统计学意义(P<0.05)。结论 H型高血压患者微量蛋白尿水平显著升高,且随着血压升高微量蛋白尿水平随之升高,临床中检测微量蛋白尿水平可反应H型高血压严重程度级对肾脏损伤程度,为临床诊断、治疗H型高血压提高有效临床依据。
Objective To investigate the H type hypertension and microalbuminuria relevance. Methods a total of 2014 April October 2015 in our hospital from H type hypertension patients with 120 cases as study group, according to the blood pressure levels divided into grade 1, grade 2 and grade 3 hypertension group, select the same period in our hospital physical examination center of healthyvolunteers 50 as control group, than turbidity approach was used to detect the patients with microalbuminuria, respectively, in comparison with the research group and the control group by immunescattering, study group of different grades of the hypertensive patients with microalbuminuria. The results of the study group patients with microalbuminuria level was significantly higher than that ofthe control group, compared with statistical significance(P < 0. 05). According to the classification criteria of hypertension and 120 cases of H type hypertension patients divided into grade 1 in 42 cases, 53 cases of grade 2, grade 3 and 25 patients. With the increase of the grade of hypertension, microalbuminuria levels increased, groups the value relatively, there is a statistically significant(P < 0.05). Conclusion H type hypertension patients with micro albuminuria levels were significantly elevated and microalbuminuria level with a rise of blood pressure increased, clinical detection of trace levelsof proteinuria can reaction of H type hypertension severity level of kidney damage, for clinical diagnosis and treatment of H type hypertension effectively improve clinical evidence.
Objective To investigate the H type hypertension and microalbuminuria relevance. Methods a total of 2014 April October 2015 in our hospital from H type hypertension patients with 120 cases as study group, according to the blood pressure levels divided into grade 1, grade 2 and grade 3 hypertension group, select the same period in our hospital physical examination center of healthyvolunteers 50 as control group, than turbidity approach was used to detect the patients with microalbuminuria, respectively, in comparison with the research group and the control group by immunescattering, study group of different grades of the hypertensive patients with microalbuminuria. The results of the study group patients with microalbuminuria level was significantly higher than that ofthe control group, compared with statistical significance(P < 0. 05). According to the classification criteria of hypertension and 120 cases of H type hypertension patients divided into grade 1 in 42 cases, 53 cases of grade 2, grade 3 and 25 patients. With the increase of the grade of hypertension, microalbuminuria levels increased, groups the value relatively, there is a statistically significant(P < 0.05). Conclusion H type hypertension patients with micro albuminuria levels were significantly elevated and microalbuminuria level with a rise of blood pressure increased, clinical detection of trace levelsof proteinuria can reaction of H type hypertension severity level of kidney damage, for clinical diagnosis and treatment of H type hypertension effectively improve clinical evidence.
引文
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[7]Juraschek,S.P.,Coresh,J.,Inker,L.A.et al.Comparison of serum concentrations ofβ-trace protein,β2-microglobulin,Cystatin C,and Creatinine in the US population[J].Clinical journal of the American Society of Nephrology:CJASN,2013,8(4):584-592.
[8]Shinzawa,M.,Yamamoto,R.,Nagasawa,Y.et al.Age and prediction of remission and relapse of proteinuria and corticosteroid-related adverse events in adult-onset minimal-change disease:A retrospective cohort study[J].Clinical and experimental nephrology,2013,17(6):839-847.
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[10]汪全海,贺连平,陈燕等.氨氯地平联合替米沙坦改善高血压合并糖尿病患者微蛋白尿效果的Meta分析[J].中国临床药理学与治疗学,2013,18(7):774-777.
[2]Suliburska,J.,Krejpcio,Z.,Staniek,H.et al.The effects of antihypertensive drugs on chromium status,glucose metabolism,and antioxidant and inflammatory indices in spontaneously hypertensive rats[J].Biological trace element research.,2014,157(1):60-66.
[3]王淑琴,黄怡,黄云峰等.老年高血压220例颈动脉硬化与微量蛋白尿的关系分析[J].武警医学,2014,25(5):513-515.
[4]曾锋,余钷,罗柳玲等.隐蔽性高血压患者靶器官损害临床分析[J].岭南心血管病杂志,2014,20(1):90-92.
[5]裘丹青,童丽君.氯沙坦对社区原发性高血压患者微量蛋白尿的影响[J].中国医师进修杂志,2013,36(16):67-68,71.
[6]陈金平,仇新军,于华等.坎地沙坦联合复方丹参滴丸治疗高血压左心室肥厚[J].临床误诊误治,2013,26(1):66-69.
[7]Juraschek,S.P.,Coresh,J.,Inker,L.A.et al.Comparison of serum concentrations ofβ-trace protein,β2-microglobulin,Cystatin C,and Creatinine in the US population[J].Clinical journal of the American Society of Nephrology:CJASN,2013,8(4):584-592.
[8]Shinzawa,M.,Yamamoto,R.,Nagasawa,Y.et al.Age and prediction of remission and relapse of proteinuria and corticosteroid-related adverse events in adult-onset minimal-change disease:A retrospective cohort study[J].Clinical and experimental nephrology,2013,17(6):839-847.
[9]夏菁,孙涛,钱扬会等.长航人员体检微量蛋白尿情况分析[J].中国急救复苏与灾害医学杂志,2014,9(5):417-418.
[10]汪全海,贺连平,陈燕等.氨氯地平联合替米沙坦改善高血压合并糖尿病患者微蛋白尿效果的Meta分析[J].中国临床药理学与治疗学,2013,18(7):774-777.