鲑鱼鱼皮胶原蛋白小分子肽的功效性研究
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- 英文论文题名：Studies on the efficacy of collagen peptides from salmon skin
- 论文作者：孔惠 ; 曹玉华 ; 曹光群
- 英文论文作者：Kong Hui ; Cao Yu hua ; Cao Guangqun ; School of Chemical and Material Engineering ; Jiangnan University
- 年：2016
- 作者机构：江南大学化学与材料工程学院;
- 论文关键词：鲑鱼皮 ; 胶原蛋白肽 ; 护肤功效性
- 英文论文关键词：salmon skin ; collagen peptides ; skin-care efficacy
- 会议召开时间：2016-06-15
- 会议录名称：第十一届中国化妆品学术研讨会论文集
- 英文会议录名称：The Proceedings of the 11th Seminar on Cosmetic China
- 语种：中文
- 分类号：O629.72;TQ658
- 学会代码：ZGXE
- 会议名称：第十一届中国化妆品学术研讨会
- 会议地点：中国上海
- 主办单位：中国香料香精化妆品工业协会
- 学会名称：中国香料香精化妆品工业协会
- 页数：6
- 文件大小：611k
- 原文格式：O
- 会议级别：全国
摘要
研究了鲑鱼皮胶原蛋白肽在美白祛斑、保湿及抗衰老方面的性能。以酪氨酸酶抑制率表征鲑鱼皮胶原蛋白肽的美白功效,结果显示鲑鱼皮胶原蛋白肽对酪氨酸羟化酶和多巴氧化酶均有抑制作用,肽浓度为30mg/mL时,对多巴氧化酶的抑制率为31%,对酪氨酸羟化酶的抑制率为28.6%。试验了鲑鱼皮胶原蛋白肽的保湿性能,并与常用保湿剂进行了比较,结果表明其保湿性能和甘油、1,3-丁二醇、聚乙二醇400接近,且优于透明质酸。考察了鲑鱼皮胶原蛋白肽对弹性蛋白酶的抑制作用,鲑鱼皮胶原蛋白肽抗衰老性能显著,IC50值为8.39mg/mL。鲑鱼皮胶原蛋白肽可作为具有多重功效的添加剂应用于化妆品中。
The effectsof collagen peptides from salmon skin on skin whitening,moisturizing and anti-aging have been studied.The efficiency of skin whitening was characterized by inhibitory activity against tyrosinase.The results showed that the collagen peptides from salmon skin had the inhibitory activityagainst tyrosine hydroxylase and dopa oxidase.Asthe concentration of collagen peptides was 30 mg/mL,the inhibition rate againsttyrosine hydroxylase and dopa oxidase was31%and 28.6%,respectively.Compared with the common used moisturizer,the collagen peptides from salmon skin have similar hygroscopicity and moisture retentionto glycerol,1,3-butanediol and PEG400,evenbetter thanhyaluronic acid.The efficiency of skin anti-aging is characterized by inhibitory activity against elastase.The result showed that the collagen peptides had high inhibitory activityagainstelastase,the IC50 value of collagen peptides from salmon skin was 8.39 mg/mL.Collagen peptides from salmon skin have multi-effects of whitening,moisturizing,anti-agingon the skin,and could be used as anadditive in cosmetics.
The effectsof collagen peptides from salmon skin on skin whitening,moisturizing and anti-aging have been studied.The efficiency of skin whitening was characterized by inhibitory activity against tyrosinase.The results showed that the collagen peptides from salmon skin had the inhibitory activityagainst tyrosine hydroxylase and dopa oxidase.Asthe concentration of collagen peptides was 30 mg/mL,the inhibition rate againsttyrosine hydroxylase and dopa oxidase was31%and 28.6%,respectively.Compared with the common used moisturizer,the collagen peptides from salmon skin have similar hygroscopicity and moisture retentionto glycerol,1,3-butanediol and PEG400,evenbetter thanhyaluronic acid.The efficiency of skin anti-aging is characterized by inhibitory activity against elastase.The result showed that the collagen peptides had high inhibitory activityagainstelastase,the IC50 value of collagen peptides from salmon skin was 8.39 mg/mL.Collagen peptides from salmon skin have multi-effects of whitening,moisturizing,anti-agingon the skin,and could be used as anadditive in cosmetics.
引文
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[9]邢晓平,杨笑笑,卢婕,等.石榴皮中鞣花酸的抗衰老性能及机理研究[J].食品与生物技术学报,2015,34(4):436~442.
[10]杜孝元,刘玮,史飞,等.酪氨酸酶活性抑制实验及其在祛斑关白化妆品功效评价中的应用[J].中国美容医学,2005,14(6):740~742.
[11]王白强,曾晓军.酪氨酸酶活性的抑制研究及皮肤关白化妆品的研制[J].福建轻纺,2002(7)1~6.
[12]刘小杰,陈启和,孙桥.弹性蛋白酶的研究进展[J].中国食品添加剂,2004(4):29~32.
[13]魏少敏.弹性蛋白降解与皮肤衰老及其护肤品开发[J].日用化学工业,1997(5):32~34.
[2]MORENO H M,MONTERO M P,G6MEZ-GUILLEN M C,etc.Collagen characteristics of farmed atlantic salmon with firm and soft fillet texture[J].Food Chemistry,2012,134(2):678-685.
[3]GILSENAN P M,ROSS-MURPHY S B.Shear creep of gelatin gels from mammalian and piscine collagens[J].International Journal of Biological Macromolecules,2001,29(1):53-61.
[4]郭瑶,曾名勇,崔文萱.水产胶原蛋白及胶原多肽的研究进展[J].水产科学,2006,25(2):101~104.
[5]ZHANG M,LIU W T,LI G Y.Isolation and characterisation of collagens from the skin of largefin longbarbel catfish(mystus macropterus)[J].Food Chemistry,2009,115(3):826-831.
[6]刘成梅,梁汉萦,刘伟.罗非鱼鱼皮多肽(TSP-I)抗氧化活性的研究[J].食品研究与开发,2007,28(11):148~151.
[7]ZHANG Y F,DUAN X,ZHUANG Y L.Purification and characterization of novel antioxidant peptides from enzymatic hydrolysates of tilapia(oreochromis niloticus)skin gelatin[J].Peptides,2012,38(1):13-21.
[8]林琳.鱼皮胶原蛋白的制备及胶原蛋白多肽活性的研究[D].青岛:中国海洋大学,2006.
[9]邢晓平,杨笑笑,卢婕,等.石榴皮中鞣花酸的抗衰老性能及机理研究[J].食品与生物技术学报,2015,34(4):436~442.
[10]杜孝元,刘玮,史飞,等.酪氨酸酶活性抑制实验及其在祛斑关白化妆品功效评价中的应用[J].中国美容医学,2005,14(6):740~742.
[11]王白强,曾晓军.酪氨酸酶活性的抑制研究及皮肤关白化妆品的研制[J].福建轻纺,2002(7)1~6.
[12]刘小杰,陈启和,孙桥.弹性蛋白酶的研究进展[J].中国食品添加剂,2004(4):29~32.
[13]魏少敏.弹性蛋白降解与皮肤衰老及其护肤品开发[J].日用化学工业,1997(5):32~34.