双子磺酸甜菜碱杂化整体柱的制备及其在极性小分子亲水色谱分离中的应用
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摘要
<正>整体柱作为新一代分离介质具有低的柱压降、传质速率快和适合微量分离等很多优点。有机–硅胶杂化整体柱同时具有无机基质部分和有机功能基团部分,它结合了有机整体柱和无机硅胶整体柱两者的优势[1],近年来备受研究者们关注。亲水色谱因其在极性化合物的分离上有着比反相色谱更大的优势,在色谱研究领域变得越来越热门。亲水色谱中用的高极性流动相对极性样品有很好的溶解性,克服了极性样品在正相色谱流动相中溶解性差的问题
引文
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