三维空间内的超声实时多点聚焦的研究
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- 英文论文题名：Research on ultrasonic real-time multiple focusing in the three dimensional space
- 论文作者：高孟娣 ; 王丛知 ; 蔡飞燕 ; 邱维宝 ; 郑海荣
- 英文论文作者：GAO Meng-di ; WANG Cong-zhi ; CAI Fei-yan ; QIU Wei-bao ; ZHENG Hai-rong ; Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Institute
- 年：2016
- 作者机构：中国科学院深圳先进技术研究院;
- 论文关键词：超声实时多点聚焦 ; 均匀性 ; 连续性 ; 神经刺激 ; 多点粒子操控
- 英文论文关键词：real-time multiple focusing ; uniformity ; continuity ; neurostimulation ; multiple particle control
- 会议召开时间：2016-10-28
- 会议录名称：2016年全国声学学术会议论文集
- 语种：中文
- 分类号：TB552
- 学会代码：OGSM
- 会议名称：2016年全国声学学术会议
- 会议地点：中国湖北武汉
- 主办单位：中国声学学会
- 学会名称：中国声学学会
- 页数：3
- 文件大小：406k
- 原文格式：D
- 会议级别：全国
摘要
基于二维面阵的三维空间内超声实时多焦点聚焦能够充分利用各个阵元的超声波能量,本文通过Random-Superposition(RS)算法,获取能够产生预先设定的多焦点的阵元激励。再叠加各个阵元激励对声场的响应,形成声场的焦点分布图像,来验证三维空间内的多点聚焦。通过给各个焦点加权,补偿能量较弱的焦点,有效增强了多焦点能量的均匀性。同时,焦点数目的增加有效提高了焦点能量的连续性。实时多焦点聚焦以其非介入性,安全性,毫米级高分辨率等优势有待应用于神经刺激、多焦点粒子操控等领域。
Real-time multiple focusing in the three dimensional space based on the 2D phased array can make full use of the ultrasonic energies of each element. In this article, the Random-Superposition(RS) algorithm is applied to determine the excitation waveform of each element which can generate the desired multiple focal points. By superposing the ultrasound field by summing up the contribution of each element's excitation, we can verify the distribution of the multiple focal points. Posing weight to each focus, the uniformity of the multiple focus is enhanced greatly by compensating the weak pressure intensity. Meantime, the continuity of the multiple focus is improved apparently by increasing the number of foci from 5 to 9. Owing to the noninvasiveness, security and the good spatial resolution at millimeter level of the real-time multiple focal points, it paves a promising way to be adopted in neurostimulation and multiple particle control, etc.
Real-time multiple focusing in the three dimensional space based on the 2D phased array can make full use of the ultrasonic energies of each element. In this article, the Random-Superposition(RS) algorithm is applied to determine the excitation waveform of each element which can generate the desired multiple focal points. By superposing the ultrasound field by summing up the contribution of each element's excitation, we can verify the distribution of the multiple focal points. Posing weight to each focus, the uniformity of the multiple focus is enhanced greatly by compensating the weak pressure intensity. Meantime, the continuity of the multiple focus is improved apparently by increasing the number of foci from 5 to 9. Owing to the noninvasiveness, security and the good spatial resolution at millimeter level of the real-time multiple focal points, it paves a promising way to be adopted in neurostimulation and multiple particle control, etc.
引文
[1]O.Naor,Y.Hertzberg,E.Zemel,E.Kimmel,and S.Shoham,"Towards multifocal ultrasonic neural stimulation II:design considerations for an acoustic retinal prosthesis,"Journal of Neural Eengineering,vol.9,no.2,p.026006,2012.
[2]E.S.Ebbini and C.A.Cain,"Multiple-focus ultrasound phased-array pattern synthesis:optimal driving-signal distributions for hyperthermia,"IEEE Trans.Ultraso.Ferroelec.Freq.Control,vol.36,no.5,pp.540-548,1989.
[3]G.Li,H.Zhao,H.Zhou,F.Yan,J.Wang,C.Xu,C.Wang,L.Niu,L.Meng,S.Wu,H.Zhang,W.Qiu,and H.Zheng,"Improved Anatomical Specificity of Non-invasive Neuro-stimulation by High Frequency(5 MHz)Ultrasound,"Sci Rep,6,24738,2016.
[4]A.Weyns,"Radiation field calculations of pulsed ultrasonic transducers:Part 1:Planar circular,square and annular transducers,"IEEE Trans.Ultraso.Ferroelec.Freq.Control,vol.18,no.4,pp.183-188,July 1980.
[5]W.Legon,T.F.Sato,A.Opitz,J.Mueller,A.Barbour,A.Williams,et al.,"Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans,"Nature Neuroscience,vol.17,no.2,pp.322-329,2014.
[6]H.Kim,A.Chiu,S.D.Lee,K.Fischer,S.S.Yoo,"Focused Ultrasound-mediated Non-invasive Brain Stimulation:Examination of Sonication Parameters",Brain Stimulation,no.7,pp.748-756,2014.
[7]W.Lee,H.Kim,Y.Jung,I.U.Song,Y.A.Chung,and S.S.Yoo,"Image-guided transcranial focused ultrasound stimulates human primary somatosensory cortex",Sci Rep,5:8743,2015.
[2]E.S.Ebbini and C.A.Cain,"Multiple-focus ultrasound phased-array pattern synthesis:optimal driving-signal distributions for hyperthermia,"IEEE Trans.Ultraso.Ferroelec.Freq.Control,vol.36,no.5,pp.540-548,1989.
[3]G.Li,H.Zhao,H.Zhou,F.Yan,J.Wang,C.Xu,C.Wang,L.Niu,L.Meng,S.Wu,H.Zhang,W.Qiu,and H.Zheng,"Improved Anatomical Specificity of Non-invasive Neuro-stimulation by High Frequency(5 MHz)Ultrasound,"Sci Rep,6,24738,2016.
[4]A.Weyns,"Radiation field calculations of pulsed ultrasonic transducers:Part 1:Planar circular,square and annular transducers,"IEEE Trans.Ultraso.Ferroelec.Freq.Control,vol.18,no.4,pp.183-188,July 1980.
[5]W.Legon,T.F.Sato,A.Opitz,J.Mueller,A.Barbour,A.Williams,et al.,"Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans,"Nature Neuroscience,vol.17,no.2,pp.322-329,2014.
[6]H.Kim,A.Chiu,S.D.Lee,K.Fischer,S.S.Yoo,"Focused Ultrasound-mediated Non-invasive Brain Stimulation:Examination of Sonication Parameters",Brain Stimulation,no.7,pp.748-756,2014.
[7]W.Lee,H.Kim,Y.Jung,I.U.Song,Y.A.Chung,and S.S.Yoo,"Image-guided transcranial focused ultrasound stimulates human primary somatosensory cortex",Sci Rep,5:8743,2015.