菜籽多肽改善小鼠睡眠功效的研究
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- 英文论文题名：Research on effect of improving slumber of rapeseed peptides
- 论文作者：王禹程 ; 马海乐 ; 洪晨 ; 刘潇 ; 王珂
- 英文论文作者：Wang Yucheng ; Ma Haile ; Hong Chen ; Liu Xiao ; Wang Ke ; College of Food and BiologyEngineering ; Jiangsu University
- 年：2016
- 作者机构：江苏大学食品与生物工程学院;
- 论文关键词：菜籽 ; 多肽 ; 改善睡眠
- 英文论文关键词：rapeseed ; polypeptides ; improve slumber
- 会议召开时间：2016-11-09
- 会议录名称：中国食品科学技术学会第十三届年会论文摘要集
- 英文会议录名称：Abstracts of the 13th Annual Meeting of CIFST
- 语种：中文
- 分类号：TS201.4
- 学会代码：ZGSP
- 会议名称：中国食品科学技术学会第十三届年会
- 会议地点：中国北京
- 主办单位：中国食品科学技术学会
- 学会名称：中国食品科学技术学会
- 页数：2
- 文件大小：106k
- 原文格式：O
- 会议级别：全国
摘要
本文研究了菜籽多肽对改善小鼠睡眠功效的研究。方法:试验组以0.1 mL/10 g·d·BW剂量对小鼠每日灌胃250 mg/mL菜籽多肽,对照组灌胃等量蒸馏水,13天后进行直接睡眠试验、戊巴比妥钠阈下剂量催眠试验、巴比妥钠睡眠潜伏期试验和延长戊巴比妥钠睡眠时间试验。同时记录小鼠体重和脏器指数用于侧面观察小鼠及其脏器健康程度。试验结果表明:相比于对照组,试验组仅在延长戊巴比妥钠睡眠时间试验中呈阳性,有协同戊巴比妥钠显著延长小鼠睡眠时间作用(p<0.05),对其余两个指标影响不明显(p>0.05)。两组小鼠体重和脏器指数均没有差异。结论:菜籽多肽短时间灌胃小鼠没有直接改善睡眠功效,但表现出延长睡眠时间的作用,有改善小鼠睡眠状况的趋势。
Objective:To investigate the effect of rapeseed polypeptides on improving slumber.Methods:Experiment include two groups,control group and test group.Mice in test group were gavaged rapeseed polypeptides with dose of 0.1 mL/10 g·d·BW under concentration of 250 mg/mL,while control group gavaged with same volume of distilled water.13 days later,we conducted the following experient:direct hypnosis experient;subthreshold dose of pentobarbital sodium hypnotic experiments;barbital sodium sleep latency experiment;prolonged pentobarbital sodium sleep time experiment.Meanwhile record the body weight and organ index of mice to show theirs health condition.Result:Rapeseed polypeptides has significant assisteffect of prolonging pentobarbital sodium sleep time of mice in test group compared with control group(p < 0.05).The body weight and organ index have no difference between control group and test group.Conclusion:Rapeseed polypeptides has tend of improving slumber.It can prolong mice sleeping time.
Objective:To investigate the effect of rapeseed polypeptides on improving slumber.Methods:Experiment include two groups,control group and test group.Mice in test group were gavaged rapeseed polypeptides with dose of 0.1 mL/10 g·d·BW under concentration of 250 mg/mL,while control group gavaged with same volume of distilled water.13 days later,we conducted the following experient:direct hypnosis experient;subthreshold dose of pentobarbital sodium hypnotic experiments;barbital sodium sleep latency experiment;prolonged pentobarbital sodium sleep time experiment.Meanwhile record the body weight and organ index of mice to show theirs health condition.Result:Rapeseed polypeptides has significant assisteffect of prolonging pentobarbital sodium sleep time of mice in test group compared with control group(p < 0.05).The body weight and organ index have no difference between control group and test group.Conclusion:Rapeseed polypeptides has tend of improving slumber.It can prolong mice sleeping time.
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