摘要
目的:对比莫沙必利与多潘立酮治疗功能性消化不良的临床效果。方法:选取98例功能性消化不良病人进行研究,以简单随机法分为Ⅰ组与Ⅱ组各49例,Ⅰ组给予莫沙必利治疗,Ⅱ组给予多潘立酮治疗,对两组各项疗效指标进行统计对比。结果:Ⅰ组各项临床症状评分、复发率、不良反应发生率均明显低于Ⅱ组,且蛋白酶、肠道消化酶和胃肠激素水平均高于Ⅱ组,P<0.05。结论:莫沙必利总体疗效要优于多潘立酮,且复发率和不良反应发生率均较低,临床价值显著。
Objective:To compare the clinical effects of mosapride versus domperidone in the treatment of functional dyspepsia.Methods:98 patients with FD were selected and divided into group Ⅰ and group Ⅱ 49 with simple random method.The patients in group Ⅰ were treated with mosapride and the groupⅡ treated with domperidone.The statistical analysis of the efficacy indexes of the two groups was made.Results:The clinical symptom score,recurrence rate and adverse reaction rate of group Ⅰ were significantly lower than those of group Ⅱ,and the levels of protease,intestinal digestive enzyme and gastrointestinal hormones were higher than those in group Ⅱ(P < 0.05).Conclusion:Mosapride has a better overall effect than domperidone,and the recurrence rate and incidence of adverse reactions are low,and the clinical value is significant.
引文
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