探讨氟康唑氯化钠注射液局部鼻腔冲洗在非侵袭型真菌性鼻窦炎治疗中的作用
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- 论文作者：黄健健
- 年：2016
- 作者机构：十堰市太和医院(湖北医药学院附属医院)耳鼻咽喉头颈外科;
- 论文关键词：氟康唑氯化钠注射液 ; 鼻腔冲洗 ; 非侵袭型真菌性鼻窦炎
- 英文论文关键词：fluconazole sodium chloride injection ; nasal irrigation ; non-invasive fungal sinusitis
- 会议召开时间：2016-11-25
- 会议录名称：湖南中医药大学学报2016/专集：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会论文集
- 语种：中文
- 分类号：R765.41
- 学会代码：HNZY
- 会议名称：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会
- 会议地点：中国广东珠海
- 主办单位：国际数字医学会、Digital Chinese Medicine
- 学会名称：湖南中医药大学期刊杂志社
- 页数：1
- 文件大小：2084k
- 原文格式：D
- 会议级别：全国
摘要
目的探究氟康唑氯化钠注射液鼻腔局部冲洗在非侵袭型真菌性鼻窦炎术后的效果。方法选取我院2014年3月~2015年9月收治的经鼻内镜手术及术后病理检查确诊的96例非侵袭型真菌性鼻窦炎患者,按照随机抽签的方式分成观察组和对照组,各48例。观察组和对照组术后分别通过氟康唑氯化钠注射液、生理盐水鼻腔冲洗治疗,对比两组VAS评分、术区上皮化时间、复发情况及治疗过程中的不良反应。结果观察组VAS评分,明显优于对照组,差异具有统计学意义,P<0.05。两组手术区上皮化时间比较,差异显著,P<0.05。观察组中无复发患者,对照组中复发例数2例,差异具有统计学意义,P<0.05。结论非侵袭型真菌性鼻窦炎术后通过氟康唑氯化钠注射液局部鼻腔冲洗治疗,临床效果较好,同时可改善患者VAS评分,复发率较低,无明显不良反应,具有重要的临床价值。
To explore fluconazole sodium chloride injection topical nasal rinse effect of non-invasive fungal sinusitis surgery. Methods in our hospital in March 2014 ~ September 2015 weretreated by endoscopic sinus surgery and postoperative pathological examination confirmed 96 cases of non-invasive fungal sinusitis patients, according to a random drawing lots divided into observationgroup and control group. each of 48 cases. Observation group and control group were respectively by fluconazole sodium chloride injection, saline nasal irrigation treatment, compared two groups VASscore, surgical epithelialization time, recurrence and treatment of adverse reactions. Results observation group VAS score was significantly better than the control group, the difference was statisticallysignificant, P <0.05. Two surgical area epithelialization time, the difference was significant, P <0.05. No patients with recurrent observation group, the control group, the number of cases of recurrence in 2 cases, the difference was significant, P <0.05. Conclusion Non-invasive fungal sinusitis after fluconazole Sodium Chloride Injection by local nasal irrigation treatment, good clinical results, whileimproving patient VAS scores, low recurrence rate, no significant adverse reactions, have important clinical value.
To explore fluconazole sodium chloride injection topical nasal rinse effect of non-invasive fungal sinusitis surgery. Methods in our hospital in March 2014 ~ September 2015 weretreated by endoscopic sinus surgery and postoperative pathological examination confirmed 96 cases of non-invasive fungal sinusitis patients, according to a random drawing lots divided into observationgroup and control group. each of 48 cases. Observation group and control group were respectively by fluconazole sodium chloride injection, saline nasal irrigation treatment, compared two groups VASscore, surgical epithelialization time, recurrence and treatment of adverse reactions. Results observation group VAS score was significantly better than the control group, the difference was statisticallysignificant, P <0.05. Two surgical area epithelialization time, the difference was significant, P <0.05. No patients with recurrent observation group, the control group, the number of cases of recurrence in 2 cases, the difference was significant, P <0.05. Conclusion Non-invasive fungal sinusitis after fluconazole Sodium Chloride Injection by local nasal irrigation treatment, good clinical results, whileimproving patient VAS scores, low recurrence rate, no significant adverse reactions, have important clinical value.
引文
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[2]肖楚志,贺广湘,邓光伟.慢性鼻窦炎术后不同疗效患者鼻粘膜β-防御素对比观察[J].南方医科大学学报,2010(7):1580—1582.
[3]叶琳,王洪鹏,李强.鱼腥草注射液联合氟康唑静脉注射治疗普胸外科术后肺部侵袭性真菌感染临床观察[J].中国中医急症,2014,23(5):900—902.