基于宏观三维石墨烯结构的抗生素荧光生物传感器
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- 英文论文题名：A Versatile Fluorescent Biosensor based on Target-Responsive Graphene Oxide Hydrogel for Antibiotic Detection
- 论文作者：赵慧敏 ; 谭冰 ; 甘小荣 ; 全燮
- 英文论文作者：Huimin Zhao ; Bing Tan ; Xiaorong Gan ; Xie Quan ; Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education ; China) ; School of Environmental Science and Technology ; Dalian University of Technology
- 年：2016
- 作者机构：大连理工大学环境学院工业生态与环境工程教育部重点实验室;
- 论文关键词：石墨烯水凝胶 ; 荧光检测 ; 适配体 ; 土霉素 ; 磺胺二甲氧哒嗪
- 会议召开时间：2016-07-01
- 会议录名称：中国化学会第30届学术年会摘要集-第二十六分会：环境化学
- 语种：中文
- 分类号：O613.71;TP212
- 学会代码：ZGHY
- 会议名称：中国化学会第30届学术年会-第二十六分会 ; 环境化学
- 会议地点：中国辽宁大连
- 主办单位：中国化学会
- 学会名称：中国化学会
- 页数：1
- 文件大小：212k
- 原文格式：D
- 会议级别：全国
摘要
宏观三维石墨烯结构,一般是通过"自下而上"的方式将二维的石墨烯片层组装成三维分级结构,因其具有较高的比表面积、导电性、电化学稳定性、刺激响应特性等特点,广泛应用于污水净化、超级电容器、锂电池等领域[1,2]。简单地将氧化石墨烯,腺嘌呤核苷和适配体进行物理混合即可形成均质的石墨烯水凝胶,表征实验的结果表明水凝胶内部为相互交联的网状结构,腺嘌呤核苷和适配体共同作为交联剂,将氧化石墨烯片层连接在一起形成三维宏观结构。将复合荧光适配体的石墨烯水凝胶应用于抗生素的检测,其中优选的水凝胶体系对土霉素(OTC)或磺胺二甲基哒嗪(SDM)的线性响应区间为25~1000μg/L,定量限(LOQ)为25μg/L。此外,该石墨烯水凝胶体系还具有一定和热稳定性和机械性能,为实现功能性多级石墨烯材料应用于分析领域奠定了基础。
A fluorescent sensing platform based on graphene oxide(GO) hydrogel was developed through a fast and facile gelation,immersion and fluorescence determination process,in which the adenosine and aptamer worked as the co-crosslinkers to connect the GO sheets and then form the three-dimensional(3D) macrostructures.The optimal hydrogel had a linear response for oxytetracycline(OTC) of 25-1000 μg/L and a limit of quantitation(LOQ) of 25 μg/L.Moreover,The as-prepared hydrogel showed high mechanical strength and thermal stability,as well as excellent sensitivity,which is expected to lay a foundation to realize the assembly of functionalized hierarchical graphene-based materials for practical applications in analytical field.
A fluorescent sensing platform based on graphene oxide(GO) hydrogel was developed through a fast and facile gelation,immersion and fluorescence determination process,in which the adenosine and aptamer worked as the co-crosslinkers to connect the GO sheets and then form the three-dimensional(3D) macrostructures.The optimal hydrogel had a linear response for oxytetracycline(OTC) of 25-1000 μg/L and a limit of quantitation(LOQ) of 25 μg/L.Moreover,The as-prepared hydrogel showed high mechanical strength and thermal stability,as well as excellent sensitivity,which is expected to lay a foundation to realize the assembly of functionalized hierarchical graphene-based materials for practical applications in analytical field.
引文
[1]Li C,Shi G Q.Adv.Mater.2014,26:3992-4012.
[2]Shen,Y.,Fang,Q.,Chen,B.Environ.Sci.Technol.2015,49:67-84.
[2]Shen,Y.,Fang,Q.,Chen,B.Environ.Sci.Technol.2015,49:67-84.