对比莫沙必利与多潘立酮治疗功能性消化不良的临床效果
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- 论文作者：韦明勇 ; 彭薛 ; 谢汶甫 ; 石小琼 ; 张姗
- 年：2016
- 作者机构：四川省科学城医院消化内科;
- 论文关键词：多功能消化不良 ; 莫沙比利 ; 多潘立酮 ; 临床效果
- 英文论文关键词：multi functional dyspepsia ; Mosa Billy ; domperidone ; clinical effect
- 会议召开时间：2016-11-25
- 会议录名称：湖南中医药大学学报2016/专集：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会论文集
- 语种：中文
- 分类号：R57
- 学会代码：HNZY
- 会议名称：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会
- 会议地点：中国广东珠海
- 主办单位：国际数字医学会、Digital Chinese Medicine
- 学会名称：湖南中医药大学期刊杂志社
- 页数：2
- 文件大小：1820k
- 原文格式：D
- 会议级别：全国
摘要
目的:比较莫沙比利与多潘立酮治疗功能性消化不良的临床效果。方法:根据不同的治疗药物,将我院收治的120例功能性消化不良患者分为莫沙比利组与多潘立酮组,比较两组患者在治疗后1w、2w、4w的有效率,以及1,3,5个月的复发率。结果:治疗1w后,多潘立酮组有效率高于莫沙比利组,治疗2w,4w后,两组有效率差异不明显。5个月累计复发率,莫沙比利组明显低于多潘立酮组,1个月,3个月的复发率差异不明显。结论:在多功能消化不良的治疗中,应用多潘立酮尽管起效快,但复发率较高,远期治疗效果不理想。莫沙比利药效温和,远期疗效好,不良反应率低。
Objective: To compare the clinical effect of Mosa Billy and domperidone in the treatment of functional dyspepsia. Methods: according to different therapeutic drugs, admitted to our hospital 120 cases of functional digestive adverse patient mosapride and domperidone group, compared two groups of patients after the treatment efficiency of 1W, 2W, 4W, and 1, 3, 5 months the recurrence rate. Results: the treatment after 1W and domperidone group have efficiency is higher than that of Mosapride group, treatment for 2 weeks, 4 weeks after, the two groupshave difference in efficiency is not obvious. 5 months of the cumulative recurrence rate, mosapride group was significantly lower than domperidone group, 1 months, 3 months, the recurrence ratewas not significantly different. Conclusion: in the treatment of functional dyspepsia, application of domperidone despite rapid onset, but the recurrence rate is high, the curative effect is not ideal. Mosa Billy has mild effect, good long-term effect and low adverse reaction rate.
Objective: To compare the clinical effect of Mosa Billy and domperidone in the treatment of functional dyspepsia. Methods: according to different therapeutic drugs, admitted to our hospital 120 cases of functional digestive adverse patient mosapride and domperidone group, compared two groups of patients after the treatment efficiency of 1W, 2W, 4W, and 1, 3, 5 months the recurrence rate. Results: the treatment after 1W and domperidone group have efficiency is higher than that of Mosapride group, treatment for 2 weeks, 4 weeks after, the two groupshave difference in efficiency is not obvious. 5 months of the cumulative recurrence rate, mosapride group was significantly lower than domperidone group, 1 months, 3 months, the recurrence ratewas not significantly different. Conclusion: in the treatment of functional dyspepsia, application of domperidone despite rapid onset, but the recurrence rate is high, the curative effect is not ideal. Mosa Billy has mild effect, good long-term effect and low adverse reaction rate.
引文
[1]沈建峰.莫沙必利和多潘立酮治疗功能性消化不良的临床效果[J].中外医学研究,2014,(16):46-47.
[2]刘洁.莫沙比利和多潘立酮治疗功能性消化不良的临床效果[J].中外医学研究,2014,(2):139-139,140.
[3]黄小娟.莫沙必利与多潘立酮治疗功能性消化不良的临床疗效比较[J].医学理论与实践,2015,(10):1325-1326.
[4]文正平.奥美拉唑联合枸橼酸莫沙必利治疗功能性消化不良的疗效观察[J].医学信息(下旬刊),2011,24(6):137-137.
[5]Xiao-Hong Sun,Feng Man,Li-Yan Pang et al.Fungal biotransformation of mosapride by Cunninghamella elegans[J].Journal of molecular catalysis,B.Enzymatic,2009,59(1/3):82-89.
[2]刘洁.莫沙比利和多潘立酮治疗功能性消化不良的临床效果[J].中外医学研究,2014,(2):139-139,140.
[3]黄小娟.莫沙必利与多潘立酮治疗功能性消化不良的临床疗效比较[J].医学理论与实践,2015,(10):1325-1326.
[4]文正平.奥美拉唑联合枸橼酸莫沙必利治疗功能性消化不良的疗效观察[J].医学信息(下旬刊),2011,24(6):137-137.
[5]Xiao-Hong Sun,Feng Man,Li-Yan Pang et al.Fungal biotransformation of mosapride by Cunninghamella elegans[J].Journal of molecular catalysis,B.Enzymatic,2009,59(1/3):82-89.