焦虑和抑郁情绪对妇科肿瘤患者细胞免疫功能的影响分析
详细信息 查看官网全文
- 论文作者：陶曲
- 年：2016
- 作者机构：湖北省应城市人民医院妇科;
- 论文关键词：焦虑 ; 抑郁 ; 妇科肿瘤患者 ; 免疫功能
- 英文论文关键词：anxiety ; Depression ; Gynecological cancer patients ; The immune function
- 会议召开时间：2016-11-25
- 会议录名称：湖南中医药大学学报2016/专集：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会论文集
- 语种：中文
- 分类号：R473.73
- 学会代码：HNZY
- 会议名称：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会
- 会议地点：中国广东珠海
- 主办单位：国际数字医学会、Digital Chinese Medicine
- 学会名称：湖南中医药大学期刊杂志社
- 页数：1
- 文件大小：1807k
- 原文格式：D
- 会议级别：全国
摘要
目的:观察研究焦虑和抑郁情绪对妇科肿瘤患者细胞免疫功能的影响分析。方法:选择2013年1月到2016年1月于我院就诊的妇科肿瘤患者伴有单纯焦虑障碍、单纯抑郁障碍和抑郁合并焦虑障碍患者各25例,同期25例无抑郁焦虑障碍患者为对照,分别比较患者的CD+4、CD+8、TNF、NK和IL-2免疫功能指标。结果:抑郁障碍患者的CD+8、IL-2和TNF显著低于对照组,两者比较有统计学意义(P<0.05),单纯焦虑障碍患者NK细胞、CD+8和IL-2显著低于对照组,两者比较有统计学意义(P<0.05),焦虑合并抑郁障碍患者NK细胞、CD+8、IL-2和TNF显著低于对照组,两者比较有统计学意义(P<0.05)。结论:焦虑和抑郁对妇科肿瘤患者的细胞免疫功能有明显的损害作用,相比于单纯焦虑障碍和单纯抑郁障碍,焦虑合并抑郁障碍患者对细胞免疫功能具有更严重的损害作用。
objective: to observe the anxiety and depression in patients with gynaecological tumor cell immune function of impact analysis. Methods: from January 2013 to January 2016 in our hospital of gynecology tumor patients with pure anxiety disorders, simple merge depression disorder and depression patients with anxiety disorders all 25 cases, 25 cases of same period withoutdepression patients with anxiety disorders for control, were compared in patients with CD + 4, CD + 8, TNF, NK and IL- 2 immune index. Results: depressive disorders in patients with CD + 8, IL- 2 and TNF was significantly lower than the control group, the comparison was statistically significant(P < 0.05),Pure anxiety disorders NK cells, CD + 8 and IL- 2 was significantly lower thancontrol group, the comparison was statistically significant(P < 0.05), patients with anxiety disorder of depression, CD + 8, NK cells, IL- 2 and TNF was significantly lower than the control group, thecomparison was statistically significant(P < 0.05). Conclusion: anxiety and depression in patients with gynaecological tumor cells have obvious damage the immune function, compared with thepure anxiety disorders and pure depressive disorder, anxiety disorder of depression patients have more serious damage of cellular immune function.
objective: to observe the anxiety and depression in patients with gynaecological tumor cell immune function of impact analysis. Methods: from January 2013 to January 2016 in our hospital of gynecology tumor patients with pure anxiety disorders, simple merge depression disorder and depression patients with anxiety disorders all 25 cases, 25 cases of same period withoutdepression patients with anxiety disorders for control, were compared in patients with CD + 4, CD + 8, TNF, NK and IL- 2 immune index. Results: depressive disorders in patients with CD + 8, IL- 2 and TNF was significantly lower than the control group, the comparison was statistically significant(P < 0.05),Pure anxiety disorders NK cells, CD + 8 and IL- 2 was significantly lower thancontrol group, the comparison was statistically significant(P < 0.05), patients with anxiety disorder of depression, CD + 8, NK cells, IL- 2 and TNF was significantly lower than the control group, thecomparison was statistically significant(P < 0.05). Conclusion: anxiety and depression in patients with gynaecological tumor cells have obvious damage the immune function, compared with thepure anxiety disorders and pure depressive disorder, anxiety disorder of depression patients have more serious damage of cellular immune function.
引文
[1]宋锐.焦虑和抑郁情绪对妇科肿瘤患者细胞免疫功能的影响[J].文摘版:医药卫生,2015(11):58-58.
[2]唐梅,吴彩霞,陈秋菊,等.焦虑和抑郁情绪对化疗前后乳腺癌患者细胞免疫功能的影响[J].重庆医学,2014(02):161-164.
[3]石苗,李中钦.谷氨酰胺对焦虑和抑郁情绪致妇科肿瘤患者细胞免疫功能低下的影响[J].中国妇幼保健,2015,30(17):2745-2747.
[4]李萌,龙德蓉.妇科恶性肿瘤患者家属焦虑抑郁状况调查及其影响因素分析[J].职业与健康,2016,32(6):795-798.
[5]许玉梅,童菲,娄宇,等.护理干预对妇科肿瘤术患者焦虑、抑郁情绪的影响研究[J].国际精神病学杂志,2016(01):168-171.
[6]Lu M,Huang M,Mai H.Influence of supportive care on anxiety and depression in patients with gynecologic malignancies[J].Chinese Nursing Research,2014.
[7]Wu S F,Lin Y H,Lee L L,et al.The Relationship Between Illness Uncertainty and Depression in Gynecologic Cancer Patients[J].Journal of Nursing&Healthcare Research,2014.
[8]Hinz A,Mehnert A,Kocalevent R D,et al.Assessment of depression severity with the PHQ-9in cancer patients and in the general population[J].Bmc Psychiatry,2015,16(1):1-8.
[9]姚启燕.对晚期肿瘤患者家属焦虑抑郁情绪探讨分析及对策[J].医学美学美容旬刊,2014(12):666-666.
[10]Sheppard V B,Harper F W K,Davis K,et al.The importance of contextual factors and age in association with anxiety and depression in Black breast cancer patients[J].Psycho-Oncology,2014,23(2):143–150.
[2]唐梅,吴彩霞,陈秋菊,等.焦虑和抑郁情绪对化疗前后乳腺癌患者细胞免疫功能的影响[J].重庆医学,2014(02):161-164.
[3]石苗,李中钦.谷氨酰胺对焦虑和抑郁情绪致妇科肿瘤患者细胞免疫功能低下的影响[J].中国妇幼保健,2015,30(17):2745-2747.
[4]李萌,龙德蓉.妇科恶性肿瘤患者家属焦虑抑郁状况调查及其影响因素分析[J].职业与健康,2016,32(6):795-798.
[5]许玉梅,童菲,娄宇,等.护理干预对妇科肿瘤术患者焦虑、抑郁情绪的影响研究[J].国际精神病学杂志,2016(01):168-171.
[6]Lu M,Huang M,Mai H.Influence of supportive care on anxiety and depression in patients with gynecologic malignancies[J].Chinese Nursing Research,2014.
[7]Wu S F,Lin Y H,Lee L L,et al.The Relationship Between Illness Uncertainty and Depression in Gynecologic Cancer Patients[J].Journal of Nursing&Healthcare Research,2014.
[8]Hinz A,Mehnert A,Kocalevent R D,et al.Assessment of depression severity with the PHQ-9in cancer patients and in the general population[J].Bmc Psychiatry,2015,16(1):1-8.
[9]姚启燕.对晚期肿瘤患者家属焦虑抑郁情绪探讨分析及对策[J].医学美学美容旬刊,2014(12):666-666.
[10]Sheppard V B,Harper F W K,Davis K,et al.The importance of contextual factors and age in association with anxiety and depression in Black breast cancer patients[J].Psycho-Oncology,2014,23(2):143–150.