超声引导下甲氨蝶呤穿刺介入治疗异位妊娠的临床研究
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- 论文作者：何平 ; 魏小华 ; 王英华 ; 王玉宁 ; 吴秀敏
- 年：2016
- 作者机构：丰宁满族自治县医院;丰宁满族自治县中医院;
- 论文关键词：异位妊娠 ; 甲氨蝶呤 ; 超声引导下穿刺 ; 介入治疗
- 英文论文关键词：ectopic pregnancy ; Methotrexate ; Ultrasound guided puncture ; Interventional therapy
- 会议召开时间：2016-11-25
- 会议录名称：湖南中医药大学学报2016/专集：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会论文集
- 语种：中文
- 分类号：R714.22
- 学会代码：HNZY
- 会议名称：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会
- 会议地点：中国广东珠海
- 主办单位：国际数字医学会、Digital Chinese Medicine
- 学会名称：湖南中医药大学期刊杂志社
- 页数：1
- 文件大小：2015k
- 原文格式：D
- 会议级别：全国
摘要
目的:对异位妊娠采用超声引导下甲氨蝶呤穿刺介入治疗的效果进行探讨。方法:选取我院2014年6月至2015年6月期间收治的68例异位妊娠患者,随机将患者分为观察组与对照组,每组34例。对照组采用单次深部肌注50mg甲氨蝶呤治疗,观察组给予超声引导下甲氨蝶呤穿刺介入治疗。对两组患者治愈率、治疗1周后包块大小、β-HCG下降至正常所用时间、月经复潮时间、住院时间及不良反应发生率等指标进行对比。结果:两组患者在月经复潮时间方面对比差异不显著,无统计学意义,P>0.05;在治愈率与输卵管再通率方面对比,观察组明显高于对照组,差异有统计学意义,P<0.05;在治疗1周后包块大小、β-HCG下降至正常所用时间、住院时间及不良反应发生率方面,观察组均低于对照组,差异有统计学意义,P<0.05。结论:对异位妊娠患者采用超声引导下甲氨蝶呤穿刺介入治疗,具有安全可靠、治愈率高、保留了患侧输卵管等优势,疗效确切,在临床中有推广的价值。
objective: to ectopic pregnancy by ultrasound guided methotrexate puncture the effect of interventional therapy were discussed. Methods: choose from June 2014 to June 2015 treated 68 cases of ectopic pregnancy patients, patients randomly divided into observation group and control group, 34 cases in each group. Control group adopts single deep muscle note 50 mg methotrexatetherapy, observation group was given ultrasound guided methotrexate targeted intervention. Cure rate, 1 week after treatment in patients with two groups of block size, beta HCG used dropped to normaltime, menstrual double tide time, length of hospital stay and the incidence of adverse reactions such as index were compared. Results: two groups of patients with double tide in the menstrual cycle timehas no significant difference compared, no statistical significance, P > 0.05; Contrast in the cure rate and the rate of fallopian tubes, observation group is significantly higher than the control group, thedifference was statistically significant, P < 0.05; In 1 week after treatment package block size, the beta HCG dropped to normal time used, length of hospital stay and the incidence of adverse reactions, observation group were lower than the control group, the difference was statistically significant, P < 0.05. Conclusion: in patients with ectopic pregnancy using ultrasonic guided methotrexate targetedintervention, with safe and reliable, high cure rate, retained the advantages of the side oviduct, curative effect, the value of popularization in clinical.
objective: to ectopic pregnancy by ultrasound guided methotrexate puncture the effect of interventional therapy were discussed. Methods: choose from June 2014 to June 2015 treated 68 cases of ectopic pregnancy patients, patients randomly divided into observation group and control group, 34 cases in each group. Control group adopts single deep muscle note 50 mg methotrexatetherapy, observation group was given ultrasound guided methotrexate targeted intervention. Cure rate, 1 week after treatment in patients with two groups of block size, beta HCG used dropped to normaltime, menstrual double tide time, length of hospital stay and the incidence of adverse reactions such as index were compared. Results: two groups of patients with double tide in the menstrual cycle timehas no significant difference compared, no statistical significance, P > 0.05; Contrast in the cure rate and the rate of fallopian tubes, observation group is significantly higher than the control group, thedifference was statistically significant, P < 0.05; In 1 week after treatment package block size, the beta HCG dropped to normal time used, length of hospital stay and the incidence of adverse reactions, observation group were lower than the control group, the difference was statistically significant, P < 0.05. Conclusion: in patients with ectopic pregnancy using ultrasonic guided methotrexate targetedintervention, with safe and reliable, high cure rate, retained the advantages of the side oviduct, curative effect, the value of popularization in clinical.
引文
[1]蒋晓春,樊静,邵明君.超声引导下甲氨蝶呤穿刺介入与腹腔镜保守手术治疗异位妊娠疗效比较[J].海峡药学,2013,01(03):151-152.
[2]刘颂华,方燕春.阴道超声引导下甲氨蝶呤介入治疗未破型异位妊娠67例分析[J].海峡药学,2013,02(08):97-99.
[3]郝春荣.腔内超声引导细针穿刺异位妊娠囊注射甲氨蝶呤治疗宫外孕的临床分析[J].中国医药指南,2016,07(16):130-131.
[4]汤彬敏,蔡敏娴,卢彩成.经阴道超声引导下注射氨甲喋呤治疗异位妊娠的临床效果[J].福建医药杂志,2014,03(12):118-121.
[5]李银华.经阴道超声引导介入治疗异位妊娠21例分析[J].中国煤炭工业医学杂志,2011,09(17):1314-1315.
[6]陈军,张琳琳,王清.阴道超声引导下介入治疗异位妊娠[J].中国现代药物应用,2011,24(04):39-40.
[7]孙仕梅.超声引导下甲氨蝶呤局部注射在异位妊娠治疗中的效果观察[J].中国医学创新,2013,35(18):122-123.
[8]梁秋燕,伍晓容,吴绿文.超声引导下孕囊穿刺注射甲氨蝶呤联合米非司酮治疗异位妊娠54例[J].中国社区医师(医学专业),2012,30(22):45-46.
[2]刘颂华,方燕春.阴道超声引导下甲氨蝶呤介入治疗未破型异位妊娠67例分析[J].海峡药学,2013,02(08):97-99.
[3]郝春荣.腔内超声引导细针穿刺异位妊娠囊注射甲氨蝶呤治疗宫外孕的临床分析[J].中国医药指南,2016,07(16):130-131.
[4]汤彬敏,蔡敏娴,卢彩成.经阴道超声引导下注射氨甲喋呤治疗异位妊娠的临床效果[J].福建医药杂志,2014,03(12):118-121.
[5]李银华.经阴道超声引导介入治疗异位妊娠21例分析[J].中国煤炭工业医学杂志,2011,09(17):1314-1315.
[6]陈军,张琳琳,王清.阴道超声引导下介入治疗异位妊娠[J].中国现代药物应用,2011,24(04):39-40.
[7]孙仕梅.超声引导下甲氨蝶呤局部注射在异位妊娠治疗中的效果观察[J].中国医学创新,2013,35(18):122-123.
[8]梁秋燕,伍晓容,吴绿文.超声引导下孕囊穿刺注射甲氨蝶呤联合米非司酮治疗异位妊娠54例[J].中国社区医师(医学专业),2012,30(22):45-46.