对一例肝硬化并发多种疾病患者的个体化药学监护
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- 英文论文题名：Individualized Pharmaceutical Care for a Patient with Hepatic Cirrhosis Complicated with Other Diseases
- 论文作者：徐璐 ; 周兴蓓 ; 武谦虎 ; 朱孝雷 ; 余爱霞 ; 邹圣强 ; 严金二
- 英文论文作者：XU Lu ; Zhou Xing-bei ; WU Qian-hu ; ZHU Xiao-lei ; YU Ai-xia ; ZOU Sheng-qiang ; YAN Jin-er ; Department of Pharmacy ; The Third People's Hospital of Zhenjiang City in Jiangsu ; Department of Liver Disease ; The Third People's Hospital of Zhenjiang City in Jiangsu ; Drug Clinical Trial Institution Office ; The Third People's Hospital of Zhenjiang City in Jiangsu ; Office of Vice Director ; The Third People's Hospital of Zhenjiang City in Jiangsu ; School of Pharmacy ; Jiangsu University
- 年：2016
- 作者机构：江苏省镇江市第三人民医院药剂科;江苏省镇江市第三人民医院肝病科;江苏省镇江市第三人民医院药物临床试验管理机构办公室;江苏省镇江市第三人民医院副院长办公室;江苏大学药学院;
- 论文关键词：药学监护 ; 肝硬化 ; 肝性脑病 ; 感染 ; 不良反应
- 英文论文关键词：Pharmaceutical care ; Hepatic cirrhosis ; Hepatic encephalopathy ; Infection ; Adver-se drug reaction
- 会议召开时间：2016-09-27
- 会议录名称：中国药学会第十三届青年药学科研成果交流会论文集
- 语种：中文
- 分类号：R575.2
- 学会代码：YYWS
- 会议名称：中国药学会第十三届青年药学科研成果交流会
- 会议地点：中国江西南昌
- 主办单位：中国药学会
- 学会名称：中国药学会
- 页数：4
- 文件大小：249k
- 原文格式：O
- 会议级别：全国
摘要
一例乙肝肝硬化并发多种疾病的男性患者,因腹膜炎入院。给予利尿、抗感染治疗好转后,相继出现肝性脑病、消化道出血、上呼吸道感染。药师全程参与药学监护,对肝腹水抗生素给药方案予以优化,弃用加重肾负担的左氧氟沙星,单用头孢地嗪;对肝性脑病降血氨药剂量调整,增加门冬氨酸鸟氨酸用量;鉴别出发热为止血药(氨甲苯酸+酚磺乙胺)引起的药物热;并建议对上感引发的左下肺炎采用高级别抗菌药亚胺培南西司他丁等,所提建议均被医生采纳,并取得积极效果。
One male patient with liver cirrhosis caused by hepatitis B complicated with other diseases was hospitalized because of peritonitis.After the condition was got better by diuretic and anti-infection treatment,the patient appeared secondary infections such as hepatic encephalopathy,gastrointestinal hemorrhage and upper respairatory tract infection.Clinical pharmacist participated in pharmaceutical care in the whole therapeutic process.Clinical pharmacist optimized the regimen of antibacterials for the treatment of liver ascites by using Cefodizime instead of Levofloxacin which caused more burden,increased the dosage of Ornithine-aspartate for curing hepatic encephalopathy,identified one drug fever caused by the two hemostatic drugs Aminomethylbenzoic Acid and Etamsylate,and suggested using Imipenem-cilastatin to treat left lower pneumonia caused by upper respiratory infections.All of the suggestions were adopted by the doctors.This pharmaceutical care appeared effectively.
One male patient with liver cirrhosis caused by hepatitis B complicated with other diseases was hospitalized because of peritonitis.After the condition was got better by diuretic and anti-infection treatment,the patient appeared secondary infections such as hepatic encephalopathy,gastrointestinal hemorrhage and upper respairatory tract infection.Clinical pharmacist participated in pharmaceutical care in the whole therapeutic process.Clinical pharmacist optimized the regimen of antibacterials for the treatment of liver ascites by using Cefodizime instead of Levofloxacin which caused more burden,increased the dosage of Ornithine-aspartate for curing hepatic encephalopathy,identified one drug fever caused by the two hemostatic drugs Aminomethylbenzoic Acid and Etamsylate,and suggested using Imipenem-cilastatin to treat left lower pneumonia caused by upper respiratory infections.All of the suggestions were adopted by the doctors.This pharmaceutical care appeared effectively.
引文
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[6]董国蕊.酚磺乙胺注射液联用氨基苯酸注射液引起药物热一例临床分析[J].中国药物与临床,2013,13(8):1102-3.
[7]王晋予.头孢类抗生素与盐酸氨溴索配伍禁忌分析[J].当代医学,2014,20(25):78-9.
[2]中华医学会消化病学分会,中华医学会肝病学分会.中国肝性脑病诊治共识意见[J].中国医学前沿杂志,2014,6(2):88-9.
[3]Sipsas NV,Kontoyiannis DP.Invasive fungal infections inpatients with cancer in the intensive care unit[J].Int J Antimicmb Agents,2012,39(6):464-466.
[4]仵利军,金惠静,徐立平.美罗培南与亚胺培南/西司他丁钠治疗细菌感染有效性和安全性的Meta分析[J].国外医药抗生素分册,2014,35(1):28-31.
[5]高玉平.酚磺乙胺联用氨甲苯酸引起药物热2例[J].药物不良反应杂志,2005,(4):295-5.
[6]董国蕊.酚磺乙胺注射液联用氨基苯酸注射液引起药物热一例临床分析[J].中国药物与临床,2013,13(8):1102-3.
[7]王晋予.头孢类抗生素与盐酸氨溴索配伍禁忌分析[J].当代医学,2014,20(25):78-9.