吗啡芬太尼曲马多及哌替啶缓解手术后躁动的比较研究
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- 英文论文题名：Morphine fentanyl Tramagetic and pethidine after the comparative study of the postoperative agitation
- 论文作者：董浩林 ; 陈国利 ; 陶国才
- 英文论文作者：Dong Haolin ; Chen Guoli ; Tao Guocai ; Department of Anesthesiology ; the 210th Hospital of Chinese PLA
- 年：2016
- 作者机构：解放军第210医院分院麻醉科;261206部队卫生大队;第三军医大学西南医院麻醉科;
- 论文关键词：全麻 ; 术后躁动 ; 哌替啶
- 英文论文关键词：anesthesia ; postoperative agitation ; pethidine
- 会议召开时间：2016-12-01
- 会议录名称：中国医师进修论文选编
- 语种：中文
- 分类号：R614
- 学会代码：BCLK
- 会议名称：2016年12月中国医师进修学术交流会
- 会议地点：中国北京
- 主办单位：中国医师进修编委会
- 学会名称：百川利康（北京）国际医学研究院
- 页数：3
- 文件大小：637k
- 原文格式：D
- 会议级别：全国
摘要
目的全麻后患者对各种有害刺激均可诱发或加重术后躁动,其中疼痛占92.44%是最常见原因。应用四种镇痛药物解除手术后病人痛觉恢复后不适。观察四种镇痛药物缓解躁动的效果。方法 ASAⅠ-Ⅱ级全麻术后,中重度躁动病人108例,随机分成四组。Ⅰ、Ⅱ、Ⅲ、Ⅳ。四组病人在出现躁动即刻分别给予四种不同镇痛药物。(除外:儿童,精神病史,麻醉药物过敏史,代谢性疾患的单胺氧化酶服药史患者,)观察并记录躁动消失时间,平静状态时间,呼吸抑制情况和清醒时间。监测项目HR MAP SPO2.结果:Ⅳ组躁动消除最快,用药即刻消除,持续平静状态时间最长,抑制呼吸轻。结论哌替啶有效控制术后病人躁动,抑制呼吸轻,用药后平稳清醒。是缓解术后躁动的有效方法。
Objective After general anesthesia patients to various harmful stimulus all can cause or worsen postoperative restless, which accounted for 92.44% of pain is the most common cause.Four analgesic drug application lift surgery patients recover pain after discomfort.Watch four analgesic drug ease restless the effect. methodsⅠ-Ⅱlevel ASA after general anesthesia, moderate to severe restless patient 108 cases were randomly divided into four groups. Ⅰ,Ⅱ, Ⅲ, Ⅳ. Four groups of patients were given immediately four different analgesic drugs when appeared restless.except: children, history of mental illness, anesthetic drugs, metabolic disorder, a history of allergies single oxidase, history, medicine patients) Watch and record the restless disappear time, calm state time, respiratory inhibition and sober time. Monitor project HR MAP SPO2.Results Ⅳgroup restless eliminate the fastest, drug use immediately eliminate, quiet condition for the longest time, control breathing light. Conclusion ] pethidine effectively control the patient restless, control breathing light, after smooth awake. Is to alleviatepostoperative restless the effective method.
Objective After general anesthesia patients to various harmful stimulus all can cause or worsen postoperative restless, which accounted for 92.44% of pain is the most common cause.Four analgesic drug application lift surgery patients recover pain after discomfort.Watch four analgesic drug ease restless the effect. methodsⅠ-Ⅱlevel ASA after general anesthesia, moderate to severe restless patient 108 cases were randomly divided into four groups. Ⅰ,Ⅱ, Ⅲ, Ⅳ. Four groups of patients were given immediately four different analgesic drugs when appeared restless.except: children, history of mental illness, anesthetic drugs, metabolic disorder, a history of allergies single oxidase, history, medicine patients) Watch and record the restless disappear time, calm state time, respiratory inhibition and sober time. Monitor project HR MAP SPO2.Results Ⅳgroup restless eliminate the fastest, drug use immediately eliminate, quiet condition for the longest time, control breathing light. Conclusion ] pethidine effectively control the patient restless, control breathing light, after smooth awake. Is to alleviatepostoperative restless the effective method.
引文
[1]旷满秀,郭曲练:麻醉恢复期患者躁动的分析与处理[J]:中国现代医学杂志,2003,13(24):108-109
[2]黎祖荣,王明德,魏佳,等.麻醉恢复室患者躁动的原因及相关因素分析[J].临床麻醉学杂志,2009,25(6)536.
[3]邓立琴,丁风兰,刘红,等全麻术后躁动255例分析[J]:实用医学杂志,2006,2(22):166-167
[4]Aouad MT,Nasr VG.Emergence agitation in children:an update[J].Curr Opin Anaesthesiol,005,182(6):614-619.
[5]Tarkkila P,Tuominen M,Lindgren L.Comparison of respiratoryeffects of tramadol and pethidine[J].Eur JAnaesthesiol,1998;15:64-8
[6]Raffa RB,Friderichs E,Reimann W,et al.Opioid and nonopioid components independently contribute to the mechanism ofaction of tramadol,an’atypical’opioid analgesic[J].J Pharmcol Exp Ther,1992;260:275-85
[7]Bamigbade TA,Langford RM.Tramadol hydrochloride:anoverview of current use[J].Hosp Med,1998;59:373-6
[8]Chan AMH,Ng KFJ,Tong EWN,et al.Control of shiveringunder regional anesthesia in obstetric patient with tramadol[J].Can J Anaesth,1999;46:253-8
[9]王寿勇,蒋昭祥.术后硬膜外阿片类镇痛药的选择[J].国外医学麻醉学与复苏册,1998,19(4):243.
[10]张树林,封雪,路道远等应用曲马多与杜冷丁预防全麻术后躁动的临床观察[J].黑龙江医学2000.10(196)20-21
[2]黎祖荣,王明德,魏佳,等.麻醉恢复室患者躁动的原因及相关因素分析[J].临床麻醉学杂志,2009,25(6)536.
[3]邓立琴,丁风兰,刘红,等全麻术后躁动255例分析[J]:实用医学杂志,2006,2(22):166-167
[4]Aouad MT,Nasr VG.Emergence agitation in children:an update[J].Curr Opin Anaesthesiol,005,182(6):614-619.
[5]Tarkkila P,Tuominen M,Lindgren L.Comparison of respiratoryeffects of tramadol and pethidine[J].Eur JAnaesthesiol,1998;15:64-8
[6]Raffa RB,Friderichs E,Reimann W,et al.Opioid and nonopioid components independently contribute to the mechanism ofaction of tramadol,an’atypical’opioid analgesic[J].J Pharmcol Exp Ther,1992;260:275-85
[7]Bamigbade TA,Langford RM.Tramadol hydrochloride:anoverview of current use[J].Hosp Med,1998;59:373-6
[8]Chan AMH,Ng KFJ,Tong EWN,et al.Control of shiveringunder regional anesthesia in obstetric patient with tramadol[J].Can J Anaesth,1999;46:253-8
[9]王寿勇,蒋昭祥.术后硬膜外阿片类镇痛药的选择[J].国外医学麻醉学与复苏册,1998,19(4):243.
[10]张树林,封雪,路道远等应用曲马多与杜冷丁预防全麻术后躁动的临床观察[J].黑龙江医学2000.10(196)20-21