基于DNA折纸术的纳米金棒精密修饰
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- 英文论文题名：Precision machining of gold nanorod by DNA origami
- 论文作者：刘冰 ; 王旭 ; 赵梦真 ; 晁洁 ; 樊春海
- 英文论文作者：Bing Liu ; Xu Wang ; Mengzhen Zhao ; Jie Chao ; Chunhai Fan ; Institute of Advanced Materials ; Nanjing University of Posts and Telecommunications ; Shanghai Institute of Applied Physics ; Chinese Academy of Sciences
- 年：2016
- 作者机构：南京邮电大学信息材料与纳米技术研究院;中国科学院上海应用物理研究所;
- 论文关键词：折纸 ; 纳米金棒 ; 表面增强拉曼
- 会议召开时间：2016-07-01
- 会议录名称：中国化学会第30届学术年会摘要集-第二十八分会：化学生物学
- 语种：中文
- 分类号：O614.123;Q523;TB383.1
- 学会代码：ZGHY
- 会议名称：中国化学会第30届学术年会-第二十八分会 ; 化学生物学
- 会议地点：中国辽宁大连
- 主办单位：中国化学会
- 学会名称：中国化学会
- 页数：1
- 文件大小：187k
- 原文格式：D
- 会议级别：全国
摘要
精确、立体的对自组装装配体上的控制研究在纳米科学和其他多个领域具有重要的意义。我们利用精密加工策略,通过特殊设计的立足点链置换反应,将三维的DNA折纸上的信息转移到纳米金棒上,从而实现对纳米金棒的特异性修饰。之后,纳米金颗粒作为质量控制部件在纳米金棒的两端和中间选择性的杂交,形成各种类型的自组装纳米结构~([1])。DNA纳米结构不仅作为构建复杂建筑的工具,更重要的是作为提供序列特异性和方向位置信息的载体。这种精密组装纳米金棒的过程展示了DNA折纸精密控制生产元件-纳米金棒的价态和朝向的能力。等离子效应,包括表面增强拉曼散射(SERS)~([2]),与自组装结构中的纳米金颗粒的数量有相当大的关联性。这种各向异质的结构对于光谱的响应很敏感,这种特性使它们在能量,光学和生物医学的领域中有很大的用途。
Precise control over functionalization of self-assembled assemblies with spatial- and stereo- regioselectivity offers a major concern in nanotechnology and holds significant promise in various areas.Here,we exploited precision machining strategy to specificly decorate a gold nanorod(AuNR) with information transferred from a DNA origami via a deliberately designed toehold-initiated DNA displacement reaction.Gold nanoparticles(AuNRs)as quality control component were selectively attached at the ends or middle location of the AuNR surface,respectively.Our study employs DNA nanostructure not only as a tool for building complex nanoarchitectures,but also discrete information carrier of sequence configuration and directionality pattern.Importantly,the produced nanorods process exhibits high precision in tailoring the valence and valence placement of production original component-AuNRs.The plasmonic responses,including surface-enhanced Raman scattering(SERS),are remarkably sensitive to the number of the AuNPs in the superstructures.The sensitive spectral response of well-defined heterostructures make them as promising coordinates for energy,optics and biomedical applications.
Precise control over functionalization of self-assembled assemblies with spatial- and stereo- regioselectivity offers a major concern in nanotechnology and holds significant promise in various areas.Here,we exploited precision machining strategy to specificly decorate a gold nanorod(AuNR) with information transferred from a DNA origami via a deliberately designed toehold-initiated DNA displacement reaction.Gold nanoparticles(AuNRs)as quality control component were selectively attached at the ends or middle location of the AuNR surface,respectively.Our study employs DNA nanostructure not only as a tool for building complex nanoarchitectures,but also discrete information carrier of sequence configuration and directionality pattern.Importantly,the produced nanorods process exhibits high precision in tailoring the valence and valence placement of production original component-AuNRs.The plasmonic responses,including surface-enhanced Raman scattering(SERS),are remarkably sensitive to the number of the AuNPs in the superstructures.The sensitive spectral response of well-defined heterostructures make them as promising coordinates for energy,optics and biomedical applications.
引文
[1]Anton K,Robert S,Hui Z,et al.Nature Material,2014,13(9):862-6.
[2]Kuhler P,Roller E M,Schreiber R,et al.Nano Letters,2014,14(5):2914-2919.
[2]Kuhler P,Roller E M,Schreiber R,et al.Nano Letters,2014,14(5):2914-2919.