紫杉醇与铂类药物用于晚期非小细胞肺癌患者治疗中的临床效果
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- 英文论文题名：Paclitaxel and platinum drugs used in the treatment of advanced non-small cell lung cancer clinical effect
- 论文作者：高立伟 ; 兰守丽 ; 闫江涛 ; 张晖 ; 武素芳 ; 左一凡
- 英文论文作者：Gao Liwei ; Lan Shouli ; Yang Jiangtao
- 年：2017
- 作者机构：河南省平顶山市平煤神马医疗集团总医院肿瘤二区;
- 论文关键词：毒副反应 ; 晚期非小细胞肺癌 ; 有效率 ; 铂类药物 ; 紫杉醇
- 英文论文关键词：Adverse reaction ; Advanced non-small cell lung cancer ; Efficient ; The platinum drugs ; paclitaxel
- 会议召开时间：2017-05-26
- 会议录名称：2017年《中国组织化学与细胞化学杂志》临床研讨会论文集
- 语种：中文
- 分类号：R734.2
- 学会代码：ZHXB
- 会议名称：2017年《中国组织化学与细胞化学杂志》临床研讨会
- 会议地点：中国湖北武汉
- 主办单位：《中国组织化学与细胞化学杂志》社有限公司
- 学会名称：《中国组织化学与细胞化学杂志》社有限公司
- 页数：1
- 文件大小：128k
- 原文格式：O
- 会议级别：全国
摘要
目的:分析晚期非小细胞肺癌救治工作中行铂类药物+紫杉醇联治疗法的有效性及其意义。方法:筛选同时分析42例因非小细胞肺癌、于2013年01月至2016年05月入住我院的晚期患者,均行铂类药物+紫杉醇联治疗法,对所选病例用药情况、预后状况展开研究。结果:42例晚期病例中,用药后其有效率是42.86%(18/42),部分患者出现肾功能受损现象、恶心呕吐现象、血小板指数异常降低、肌肉组织/关节组织疼痛异常或者是白细胞指数异常降低现象等,停药期予以对症治疗后,毒副反应都已消失。结论:对于处于疾病晚期的非小细胞肺癌患者,选择铂类药物+紫杉醇联治疗法效果突出,推荐应用。
Objective:Analysis of advanced non-small cell lung cancer treatment work the effectiveness of the bank of China platinum drugs + league taxol and its significance.Methods:Screening and analysis of 42 patients with non-small cell lung cancer,from January 2013 to May 2016 in our hospital patients with late,all line + league taxol,platinum drugs for selected cases of drug use situation,the prognosis study condition.Results:42 cases of late cases,after its effectiveness is 42.86%(18/42),some patients appear kidney damage phenomenon,nausea,vomiting,abnormal platelet index decrease,abnormal muscle/joint pain,or is to reduce leucocyte index of abnormal phenomena,such as drug withdrawal period after symptomatic treatment,adverse symptoms have disappeared.Conclusion:for patients with non-small cell lung cancer in the terminal stage of disease,selection of platinum drugs plus paclitaxel league therapy effect is outstanding,recommended.
Objective:Analysis of advanced non-small cell lung cancer treatment work the effectiveness of the bank of China platinum drugs + league taxol and its significance.Methods:Screening and analysis of 42 patients with non-small cell lung cancer,from January 2013 to May 2016 in our hospital patients with late,all line + league taxol,platinum drugs for selected cases of drug use situation,the prognosis study condition.Results:42 cases of late cases,after its effectiveness is 42.86%(18/42),some patients appear kidney damage phenomenon,nausea,vomiting,abnormal platelet index decrease,abnormal muscle/joint pain,or is to reduce leucocyte index of abnormal phenomena,such as drug withdrawal period after symptomatic treatment,adverse symptoms have disappeared.Conclusion:for patients with non-small cell lung cancer in the terminal stage of disease,selection of platinum drugs plus paclitaxel league therapy effect is outstanding,recommended.
引文
[1]侯秀珍,杨宏.多西紫杉醇加铂类2周给药治疗晚期非小细胞肺癌患者的疗效、毒副反应和生活质量[J].中国老年学杂志,2013,33(9):2145-2147.
[2]陈婵娟,陈昌南,林云笑,等.替吉奥与紫杉醇联合铂类治疗老年中晚期非小细胞肺癌的临床对比分析[J].赣南医学院学报,2015,35(1):73-75.
[3]廖茂良,叶银燕,熊娅琳.核苷酸切除修复交叉互补基因1、核苷酸还原酶M1亚基及β-微管蛋白Ⅲ表达与非小细胞肺癌术后含铂类化疗方案治疗疗效的关系[J].中国基层医药,2014,21(1):70-72.
[4]周彩存,吴一龙,孙燕,等.组织学类型对培美曲塞治疗中国晚期非小细胞肺癌二线及一线后维持治疗患者的综合分析[J].中华肿瘤杂志,2014,36(1):29-33.
[2]陈婵娟,陈昌南,林云笑,等.替吉奥与紫杉醇联合铂类治疗老年中晚期非小细胞肺癌的临床对比分析[J].赣南医学院学报,2015,35(1):73-75.
[3]廖茂良,叶银燕,熊娅琳.核苷酸切除修复交叉互补基因1、核苷酸还原酶M1亚基及β-微管蛋白Ⅲ表达与非小细胞肺癌术后含铂类化疗方案治疗疗效的关系[J].中国基层医药,2014,21(1):70-72.
[4]周彩存,吴一龙,孙燕,等.组织学类型对培美曲塞治疗中国晚期非小细胞肺癌二线及一线后维持治疗患者的综合分析[J].中华肿瘤杂志,2014,36(1):29-33.