离子液体介质中酶催化棕榈酸壳聚糖酯的合成及其表征
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- 英文论文题名：Methode of Lipase-Catalyzed Synthesis of Palmitic Chitosan ester in lonic Liquids and its characterization
- 论文作者：稂雄妃 ; 王凤丽 ; 眭梁梁 ; 林丹 ; 李晓凤 ; 赵光磊
- 英文论文作者：Xiongfei Lang ; Fengli Wang ; Liangliang Sui ; Dan Lin ; Xiaofeng Li ; Guanglei Zhao ; State Key Laboratory of Pulp and Paper Engineering ; South China University of Technology ; College of Food Science and Engineering ; South China University of Technology
- 年：2016
- 作者机构：华南理工大学制浆造纸工程国家重点实验室;华南理工大学食品科学与工程学院;
- 论文关键词：长链壳聚糖酯 ; 酶催化 ; 离子液体 ; 取代度
- 会议召开时间：2016-07-01
- 会议录名称：中国化学会第30届学术年会摘要集-第三十三分会：绿色化学
- 语种：中文
- 分类号：O636;O643.3
- 学会代码：ZGHY
- 会议名称：中国化学会第30届学术年会-第三十三分会 ; 绿色化学
- 会议地点：中国辽宁大连
- 主办单位：中国化学会
- 学会名称：中国化学会
- 页数：1
- 文件大小：190k
- 原文格式：D
- 会议级别：全国
摘要
长链脂肪酸壳聚糖酯是壳聚糖改性的一种重要衍生物,在生物和医学材料上具有广泛的应用前景。本研究采用离子液体1-乙基-3-甲基咪唑醋酸盐[EMIM]Ac和1-丁基-3-甲基咪唑四氟硼酸盐[BMIM][BF4]作为壳聚糖和棕榈酸甲酯转酯化反应介质。探讨了不同离子液体质量比、棕榈酸甲酯与氨基葡萄糖单元物质的量之比、脂肪酶用量、反应温度和反应时间等因素对棕榈酸壳聚糖酯取代度的影响。实验结果表明:在最优的条件下,棕榈酸壳聚糖酯最大的取代度达0.21,通过傅里叶红外光谱、核磁共振、XRD和热重对其进行结构和性能表征。XRD表明,在酯化改性过程中,壳聚糖的结晶度相比原壳聚糖有所下降。TG数据表明,酯化产物的热稳定性相对于原壳聚糖总体有所提高。本研究首次在离子液体中用酶催化合成长链壳聚糖酯。
Long-chain fatty acid chitosan esters are important modified chitosan products with attractive application prospects in the material of biological and biomedical. Enzymatic esterification of chitosan with palmitic acid methyl ester was investigated by using ionic liquids [EMIM]Ac and [BMIM][BF4] as reaction media in this paper. The effect of reaction parameters such as quality ratio of two kinds of ionic liquids, molar ratio of palmitic acid methyl ester/glucosamin, the lipase dosage and reaction temperature as well as reaction time on the degree of substitution(DS) of palmitic chitosan ester was studied. The maximum DS was 0.21 under the given conditions. The structure and property were confirmed according to FT-IR and NMR, X-ray diffraction(XRD) data indicated the crystallographic properties of native chitosan were disrupted during modification process. The thermal stability of the chitosan esters were promoted compared to native chitosan according to TG data. This paper first synthsis chitosan esters in ionic liquids.
Long-chain fatty acid chitosan esters are important modified chitosan products with attractive application prospects in the material of biological and biomedical. Enzymatic esterification of chitosan with palmitic acid methyl ester was investigated by using ionic liquids [EMIM]Ac and [BMIM][BF4] as reaction media in this paper. The effect of reaction parameters such as quality ratio of two kinds of ionic liquids, molar ratio of palmitic acid methyl ester/glucosamin, the lipase dosage and reaction temperature as well as reaction time on the degree of substitution(DS) of palmitic chitosan ester was studied. The maximum DS was 0.21 under the given conditions. The structure and property were confirmed according to FT-IR and NMR, X-ray diffraction(XRD) data indicated the crystallographic properties of native chitosan were disrupted during modification process. The thermal stability of the chitosan esters were promoted compared to native chitosan according to TG data. This paper first synthsis chitosan esters in ionic liquids.
引文
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[2]Zhang,H;Wu,J;Zhang,,J;He,J.Macromolecules,2005,38(20):8272
[2]Zhang,H;Wu,J;Zhang,,J;He,J.Macromolecules,2005,38(20):8272