急性脑梗死患者同型半胱氨酸及凝血纤溶指标检测
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- 论文作者：王禺 ; 易福凌 ; 高洁 ; 李宁
- 年：2016
- 作者机构：陕西省西安市第一医院;
- 论文关键词：同型半胱氨酸 ; 凝血纤溶指标 ; 急性脑梗死 ; 标志物
- 英文论文关键词：homocysteine ; Coagulation fibrinolytic indexes ; Acute cerebral infarction ; markers
- 会议召开时间：2016-11-25
- 会议录名称：湖南中医药大学学报2016/专集：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会论文集
- 语种：中文
- 分类号：R743.33
- 学会代码：HNZY
- 会议名称：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会
- 会议地点：中国广东珠海
- 主办单位：国际数字医学会、Digital Chinese Medicine
- 学会名称：湖南中医药大学期刊杂志社
- 页数：1
- 文件大小：2111k
- 原文格式：D
- 会议级别：全国
摘要
目的:探讨同型半胱氨酸及凝血纤溶指标在急性脑梗死患者中的检测意义。方法:选择2014年3月至2015年5月来我院急诊科就诊的急性脑梗死患者40例(实验组)与同期健康体检者40例(对照组)为研究对象,比较实验组治疗前后及两组患者之间血液中各项指标的变化情况。结果:实验组患者治疗前Hcy(半胱氨酸)、t-PA(纤溶酶原激活剂)、NT-pro BNP(B型脑钠肽前体)以及PAI-1(纤溶酶原激活物抑制剂-1)的水平明显高于治疗后及对照组,APTT(活化部分凝血活酶时间)明显短于治疗后及对照组,差异明显,具有统计学意义(P<0.05)。结论:Hcy、NT-pro BNP、APTT、PAI-1以及t-PA与急性脑梗死的发生发展有着密切联系,可以作为判断急性脑梗死患者病情变化及预后的标志。
objective: to study the homocysteine and coagulation fibrinolytic indexes detection significance in patients with acute cerebral infarction,Methods: in March 2014 to May 2015 tothe hospital emergency department visits of 40 patients with acute cerebral infarction(experimental group) compared with healthy check-up 40 cases(control group) as the research object, comparisonbetween the experimental group and two groups of patients before and after the treatment the change of the indicators in the blood,Results: the patients before treatment of Hcy(cysteine), t- PA(fibrinolyticenzyme activator), NT- pro BNP(b-type brain natriuretic peptide precursor) and PAI- 1-1 original activators(fibrinolytic enzyme inhibitors) levels were significantly higher than those after treatment andthe control group, and APTT(activated clotting time live enzymes) significantly shorter than and the control group after treatment, obvious differences, statistically significant(P < 0.05). Conclusion: Hcy, NT- pro BNP, APTT, PAI- 1, and t- PA and closely related to the occurrence of acute cerebral infarction development, can serve as a judge condition changes and prognosis in patients with acutecerebral infarction.
objective: to study the homocysteine and coagulation fibrinolytic indexes detection significance in patients with acute cerebral infarction,Methods: in March 2014 to May 2015 tothe hospital emergency department visits of 40 patients with acute cerebral infarction(experimental group) compared with healthy check-up 40 cases(control group) as the research object, comparisonbetween the experimental group and two groups of patients before and after the treatment the change of the indicators in the blood,Results: the patients before treatment of Hcy(cysteine), t- PA(fibrinolyticenzyme activator), NT- pro BNP(b-type brain natriuretic peptide precursor) and PAI- 1-1 original activators(fibrinolytic enzyme inhibitors) levels were significantly higher than those after treatment andthe control group, and APTT(activated clotting time live enzymes) significantly shorter than and the control group after treatment, obvious differences, statistically significant(P < 0.05). Conclusion: Hcy, NT- pro BNP, APTT, PAI- 1, and t- PA and closely related to the occurrence of acute cerebral infarction development, can serve as a judge condition changes and prognosis in patients with acutecerebral infarction.
引文
[1]代凌.急性脑梗死患者同型半胱氨酸及凝血纤溶相关指标的检测及意义[J].贵阳医学院学报,2014,39(5):713-716.
[2]陈芳.C反应蛋白、D-二聚体及同型半胱氨酸的变化与急性脑梗死的关系[J].中国实用神经疾病杂志,2012,15(19):42-43.
[3]李武,谢小兵.急性脑梗死患者相关生化指标检测的临床意义[J].现代生物医学进展,2011,11(2):283-286.
[4]殷丽.急性脑梗死患者纤溶、凝血及CRP检测的意义[J].医疗装备,2011,24(3):51-53.
[2]陈芳.C反应蛋白、D-二聚体及同型半胱氨酸的变化与急性脑梗死的关系[J].中国实用神经疾病杂志,2012,15(19):42-43.
[3]李武,谢小兵.急性脑梗死患者相关生化指标检测的临床意义[J].现代生物医学进展,2011,11(2):283-286.
[4]殷丽.急性脑梗死患者纤溶、凝血及CRP检测的意义[J].医疗装备,2011,24(3):51-53.