作者机构:Center for Endemic Disease Control,Chinese Center for Disease Control and Prevention, Harbin Medical University;Department of Biochemistry and Molecular Biology, Harbin Medical University;Department of Clinical Oncology, Harbin Medical University Cancer Hospital;
<正>Background:High iodine inhibits papillary thyroid carcinoma cell proliferation associated with TGFβ pathwayactivation,although thyroid cancers are frequently refractory to TGFβsignaling.The TGFβpathway is proved to be regulated by mi R-146b-5p.Micro RNAs are small noncoding RNAs that inhibit target m RNA translation and have emerged as potent