基于皮肤模型的抗氧化功效测试研究进展
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- 英文论文题名：The Progress of Research AboutTesting the Effect of Antioxidant Based on Human Cutaneous Models
- 论文作者：柯逸晖 ; 程树军 ; 谈伟君
- 英文论文作者：Ke Yi-hui ; Cheng Shu-jun ; Tan Wei-jun ; Guangdong Pharmaceutical University ; Guangdong Inspection and Quarantine Technology Center
- 年：2016
- 作者机构：广东药学院;广东出入境检验检疫局技术中心;
- 论文关键词：皮肤模型 ; 抗氧化 ; 功效
- 英文论文关键词：human cutaneous model ; antioxidant ; effect
- 会议召开时间：2016-06-15
- 会议录名称：第十一届中国化妆品学术研讨会论文集
- 英文会议录名称：The Proceedings of the 11th Seminar on Cosmetic China
- 语种：中文
- 分类号：TQ658
- 学会代码：ZGXE
- 会议名称：第十一届中国化妆品学术研讨会
- 会议地点：中国上海
- 主办单位：中国香料香精化妆品工业协会
- 学会名称：中国香料香精化妆品工业协会
- 页数：7
- 文件大小：470k
- 原文格式：O
- 会议级别：全国
摘要
皮肤作为机体最外层保护屏障,直接暴露于外界环境。紫外线、化学物质和污染物等产生的氧化应激会对人体皮肤产生危害,因而抗氧化损伤成为个人护理产品研发的重点。化妆品、植物及其提取物抗氧化功效的评估可采用化学方法,细胞方法和3D模型方法。随着重建人类皮肤模型的成熟,将其运用于化妆品抗氧化功效的检测是未来主要的发展趋势,并得到越来越广泛的应用。
Skin is the protection barrier at outer most layer,exposing to the environment directly.Oxidative stress which is produced by ultraviolet radiation,chemicals and pollutant will do harm to the people,thus personal care focuses on the antioxidative damage.The evaluation ways of the antioxidative effect of cosmetic,botany and botanical extracts include chemical methods,cytological methods and 3D model methods.With the development of the construction of human cutaneous models,it is the main developmental trend in the future that the construction of human cutaneous models are applied in the test of the antioxidative effect of the comestic.
Skin is the protection barrier at outer most layer,exposing to the environment directly.Oxidative stress which is produced by ultraviolet radiation,chemicals and pollutant will do harm to the people,thus personal care focuses on the antioxidative damage.The evaluation ways of the antioxidative effect of cosmetic,botany and botanical extracts include chemical methods,cytological methods and 3D model methods.With the development of the construction of human cutaneous models,it is the main developmental trend in the future that the construction of human cutaneous models are applied in the test of the antioxidative effect of the comestic.
引文
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[15]Afaq F,Adhami VM,Ahmad N,Mukhtar H.Botanical antioxidants for chemoprevention of photocarcinogenesis.Front Biosci2002,7,784-d792.
[16]Santa-Maria,C,et al.,Protection against free radicals(UVB irradiation)of a water soluble enzymatic extract from rice bran.Study using human keratinocyte monolayer and reconstructed human epidermis.Food and Chemical Toxicology,2010.48(1):83-88.
[17]Okai,Y.,Higashi-Okai,K.,2006.Radical-scavenging activity of hot water extract of Japanese rice bran-association with phenolic acids.J.UOEH 8,1-12.
[18]Menzel,D.B..Ozone.an overview of its toxicity in man and animals.Journal of Toxicology and Environmental Health.1984,13,183-204.
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[24]Martin R,Pierrard C,Lejeune F,Hilaire P,Breton L,Bernerd F.Photoprotective effect of a watersoluble extract of Rosmarinus officinalis L.against UV-induced matrix metalloproteinase-1 in human dermal fibroblasts and reconstructed skin.Eur J Dermatol 2008,18,128-135.
[25]Moore JO,Wang Y,Stebbins WG,Gao D,Zhou X,Phelps R,Lebwohl M,Wei H.Photoprotective effect of isoflavone genistein on ultraviolet B-induced pyrimidine dimer formation and PCNA expression in human reconstituted skin and its implications in dermatology and prevention of cutaneous carcinogenesis.Carcinogenesis2006,27,1627-1635.
[26]A.T.Grazul-Bilska,J.J.Bilski,D.A.Redmer,L.RReynolds,K.M.Abdullah,A.Abdulah.Antioxidant capacity of 3D human skin EpiDermTM model:effect of skin moisturizers.International Journal of Cosmetic Science.2009,31,201-208.
[27]Marisa Meloni,Anne Farina,Barbara de Servi.Molecular modifications of dermal and epidermal biomarkers following UVA exposures on reconstructed full-thickness human skin.Photochemical&Photobiological Sciences.2010,9,439-447.
[28]Hye-Ryung Choi,Youn-A Kang,Jung-Won Shin,Jung-Im Na,Chang-Hum Huh,Kyoung-Chan Park.Redox Status Is Critical for Sternness in Skin Equivalents.Oxidative Medicine and Cellular Longevity.2012,7,1-7.
[29]Laura Calvo-Casto,Deeba N.Syed,Jean C.Chamcheu,Fernanda M.P.Vilela,Ana M.Perez,Fabrice Vaillant,Miguel Rojas,Hasan Mukhtar.Protective Effect of Tropical Highland Blackberry Juice(Rubus adenotrichos Schltdl.)Against UVB-Mediated Damage in Human Epidermal Keratinocytes and in a Reconstituted Skin Equivalent Model.Photochem Photobiol.2013,89(5),1199-1207.
[2]Yaar,M.,Gilchrest,B.A..Photoageing:mechanism,prevention and therapy.Br.J.Dermatol.2007,157,874-887.
[3]Sies,H.,Stahl,W..Nutritional protection against skin damage from sunlight.Annu.Rev.Nutr.2004,24,173-200.
[4]Kohen,R,,Gati,I..Skin low molecular weight antioxidants and their role in aging and in oxidative stress.Toxicology.2000,148,149-157.
[5]Juliano,C,Cossu,M.,Alamanni,M.C.,Piu,L..Antioxidant activity of gammaoryzanol:Mechanism of action and its effect on oxidative stability of pharmaceutical oils.Int.J.Pharm.2005,299,146-154.
[6]Lupo,M.P..Antioxidants and vitamins in cosmetics.Clin.Dermatol.2001,19,467-473.
[7]L.Li,M.Fukunaga-Kalabis,and M.Herlyn,"The threedimensional human skin reconstruct model:a tool to study normal skin and melanoma progression,"Journal of Visualized Experiments,No.54,Article ID e2937,2011.
[8]M.Nagasawa,H.Hayashi,and T.Nakayoshi,"In vitro evaluation of skin sensitivity of povidone-iodine and other antiseptics using a three-dimensional human skin model,"Dermatology,supplement 1,2002,204,109-113.
[9]Natsch,A.and Wasescha,M.Fragrance raw materials and essential oils can reduce prostaglandin Eformation in keratinocytes and reconstituted human epidermis.Int.J.Cosmet.Sci.2007,29,369-376.
[10]Adhami VM,Syed DN,Khan N,Afaq F.Phytochemicals for prevention of solar ultraviolet radiation-induced damages.Photochem Photobiol2008;84:489-500.
[11]Bachelor MA,Bowden GT.UVA-mediated activation of signaling pathways involved in skin tumor promotion and progression.Semin Cancer Biol 2004;14:131-138.
[12]Lubeck RP,Berneburg M,Trelles M,Friguet B,Ogden S,Esrefoglu M,Kaya G,Goldberg DJ,Mordon S,Calderhead RG,Griffiths CE,Saurat JH,Thappa DM.How best to halt and/or revert UV-induced skin ageing:strategies,facts and fiction.Exp Dermatol 2008,17,228-240.
[13]Afaq F,Mukhtar H.Botanical antioxidants in the prevention of photocarcinogenesis and photoaging.Exp Dermatol 2006,15,678-684.
[14]Afaq,F.,et al.,Protective effect of pomegranate derived products on UVB-mediated damage in human reconstituted skin.Experimental Dermatology,2009.18(6),553-561.
[15]Afaq F,Adhami VM,Ahmad N,Mukhtar H.Botanical antioxidants for chemoprevention of photocarcinogenesis.Front Biosci2002,7,784-d792.
[16]Santa-Maria,C,et al.,Protection against free radicals(UVB irradiation)of a water soluble enzymatic extract from rice bran.Study using human keratinocyte monolayer and reconstructed human epidermis.Food and Chemical Toxicology,2010.48(1):83-88.
[17]Okai,Y.,Higashi-Okai,K.,2006.Radical-scavenging activity of hot water extract of Japanese rice bran-association with phenolic acids.J.UOEH 8,1-12.
[18]Menzel,D.B..Ozone.an overview of its toxicity in man and animals.Journal of Toxicology and Environmental Health.1984,13,183-204.
[19]Pryor,M.A.,Squadrito,G.L.,Friedman,M..The cascade mechanism to explain ozone toxicity:the role of lipid ozonation products.Free Radicals Biology and Medicine.1995,19,935-941.
[20]L.Onno,PJustine,S.Lamure,P.Catroux,J.Cotovio.Generation of oxidative stress in human cutaneous models following in vitro ozone exposure.Toxicology in Vitro.2001,15,357-362.
[21]Buss.H.,Chan.T.P.,Sluis.K.B.,Domingan,N.M.,Winterbourn,C.C..Protein carbonyl measurement by sensitive ELISA method.Free Radicals in Biology and Medicine.1997,23,361-366.
[22]Giuseppe V.,Claudia S.,Giuseppe B.,Franco C,.Vitamin C Compound Mixtures Prevent Ozone-Induced Oxidative Damage in Human Keratinocytes as Initial Assessment of Pollution Protection.Plos One.2015,10:1-15.
[23]Bernerd F,Asselineau D.An organotypic model of skin to study photodamage and photoprotection in vitro.J Am Acad Dermatol 2008;58(5 Suppl2),S155-S159.
[24]Martin R,Pierrard C,Lejeune F,Hilaire P,Breton L,Bernerd F.Photoprotective effect of a watersoluble extract of Rosmarinus officinalis L.against UV-induced matrix metalloproteinase-1 in human dermal fibroblasts and reconstructed skin.Eur J Dermatol 2008,18,128-135.
[25]Moore JO,Wang Y,Stebbins WG,Gao D,Zhou X,Phelps R,Lebwohl M,Wei H.Photoprotective effect of isoflavone genistein on ultraviolet B-induced pyrimidine dimer formation and PCNA expression in human reconstituted skin and its implications in dermatology and prevention of cutaneous carcinogenesis.Carcinogenesis2006,27,1627-1635.
[26]A.T.Grazul-Bilska,J.J.Bilski,D.A.Redmer,L.RReynolds,K.M.Abdullah,A.Abdulah.Antioxidant capacity of 3D human skin EpiDermTM model:effect of skin moisturizers.International Journal of Cosmetic Science.2009,31,201-208.
[27]Marisa Meloni,Anne Farina,Barbara de Servi.Molecular modifications of dermal and epidermal biomarkers following UVA exposures on reconstructed full-thickness human skin.Photochemical&Photobiological Sciences.2010,9,439-447.
[28]Hye-Ryung Choi,Youn-A Kang,Jung-Won Shin,Jung-Im Na,Chang-Hum Huh,Kyoung-Chan Park.Redox Status Is Critical for Sternness in Skin Equivalents.Oxidative Medicine and Cellular Longevity.2012,7,1-7.
[29]Laura Calvo-Casto,Deeba N.Syed,Jean C.Chamcheu,Fernanda M.P.Vilela,Ana M.Perez,Fabrice Vaillant,Miguel Rojas,Hasan Mukhtar.Protective Effect of Tropical Highland Blackberry Juice(Rubus adenotrichos Schltdl.)Against UVB-Mediated Damage in Human Epidermal Keratinocytes and in a Reconstituted Skin Equivalent Model.Photochem Photobiol.2013,89(5),1199-1207.