Age and severity matched comparison of gender differences in the prevalence of periodic limb movements during sleep in patients with obstructive sleep apnea
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摘要
Purpose The aim of this study was to investigate gender dif- ferences of periodic limb movements during sleep(PLMS) in patients with obstructive sleep apnea(OSA).Methods This was a casecontrol study recruiting 364 pa- tients with OSA(182 men,182 women) matched for age and apnea-hypopnea index(AHI).All participants underwent overnight polysomnography(PS6),followed by the multiple sleep latency test(MSLT) and the Epworth Sleepiness Scale(ESS).Results Women with OSA had a significantly higher preva- lence of PLMS than men(24.2 vs.15.9%,p<0.05).Women with OSA showed an increased prevalence of PLMS com- pared to men in the younger group aged S55 years(23.0 vs.10.6%,p<0.05),but not in the older groups >55 years(25.3vs.21.6%,p>0.05).Binary linear regression analysis in OSA patients confirmed that women were more likely to have PLMS than men(OR 1.71,95%CI 1.00-2.92),particularly in patients with agePurpose The aim of this study was to investigate gender dif- ferences of periodic limb movements during sleep(PLMS) in patients with obstructive sleep apnea(OSA).Methods This was a casecontrol study recruiting 364 pa- tients with OSA(182 men,182 women) matched for age and apnea-hypopnea index(AHI).All participants underwent overnight polysomnography(PS6),followed by the multiple sleep latency test(MSLT) and the Epworth Sleepiness Scale(ESS).Results Women with OSA had a significantly higher preva- lence of PLMS than men(24.2 vs.15.9%,p<0.05).Women with OSA showed an increased prevalence of PLMS com- pared to men in the younger group aged S55 years(23.0 vs.10.6%,p<0.05),but not in the older groups >55 years(25.3vs.21.6%,p>0.05).Binary linear regression analysis in OSA patients confirmed that women were more likely to have PLMS than men(OR 1.71,95%CI 1.00-2.92),particularly in patients with age
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