Plk1 inhibition leads to a failure of mitotic division during the first mitosis in pig embryos
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- 英文论文题名：Plk1 inhibition leads to a failure of mitotic division during the first mitosis in pig embryos
- 论文作者：张子霄 ; Changchao Chen ; Panpan Cui ; Yaya Liao ; Yue Zhang ; Lingyun Yao ; Rong Rui ; 剧世强
- 英文论文作者：Zixiao Zhang ; Changchao Chen ; Panpan Cui ; Yaya Liao ; Yue Zhang ; Lingyun Yao ; Rong Rui ; Shiqiang Ju ; College of Veterinary Medicine ; Nanjing Agricultural University
- 年：2016
- 作者机构：College of Veterinary Medicine,Nanjing Agricultural University;
- 会议召开时间：2016-10-22
- 会议录名称：中国畜牧兽医学会兽医产科学分会第十三次学术研讨会论文集
- 语种：英文
- 分类号：S828
- 学会代码：ZGXJ
- 会议名称：中国畜牧兽医学会兽医产科学分会第十三次学术研讨会
- 会议地点：中国浙江宁波
- 主办单位：中国畜牧兽医学会兽医产科学分会
- 学会名称：中国畜牧兽医学会
- 页数：1
- 文件大小：142k
- 原文格式：O
- 会议级别：全国
摘要
<正>Materials and Methods:This study was conducted to investigate the dynamic distribution and possible roles of Polo-like 1 kinase(Plk1)during the first mitosis process in early porcine embryo development.Indirect immunofluorescence and confocal microscopic imaging technique combined with western blot were used to study the dynamic expression and subcellular localization of the Plk1 protein.Finally,a selective Plk1 inhibitor GSK461364 was used to evaluate the potential roles of Plk1 during this special
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