对比超声引导穿刺与盲穿细针抽吸对甲状腺恶性肿瘤的诊断价值
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摘要
对比超声引导穿刺与盲穿细针抽吸细胞学方法对甲状腺恶性肿瘤诊断的准确性。收集近9年经手术病理证实的甲状腺恶性肿瘤,术前经细针抽吸细胞学和超声引导穿刺组织学活检,比较两种检查方法的诊断价值。465例甲状腺恶性肿瘤患者,平均年龄42.24岁(15~80岁),女:男=3.89:1;甲状腺乳头状癌446例(95.91%),其他恶性病变19例(4.09%)。细针抽吸351例,正确诊断192例(55.01%),误判146例(41.83%),不能确定11例(3.15%),总体误诊157例(44.98%);超声引导116例,正确诊断93例(80.17%),误判19例(16.37%),不能确定3例(2.58%),总体误诊22例(18.96%)。两种方法比较有显著性差异。对甲状腺恶性肿瘤的术前病理检查,超声引导穿刺组织学活检的准确性明显高于细针抽吸细胞学方法。
Compare the diagnostic accuracy of fine-needle aspiration and ultrasound-guided core-needle histologic biopsy of thyroid malignant tumors.Retrospective analysis of thyroid malignant tumors in last 9 years which finally confirmed by pathologically results after surgery. All the cases received preoperative fine needle aspiration(FNA) or ultrasound-guided core-needle histologic biopsy(CNB), and compare the diagnostic accuracy between them.465 patients with thyroid malignant tumors, with an average age of 42.24 years( 15 to 80 years old), female: male = 3.89 : 1; 446 cases of papillary thyroid carcinoma(95.91%), 19 cases of other malignant tumors(4.09%). 351 FNA cases,192(55.01%) cases with correct diagnosis compare with 146( 41.83%) incorrect cases, and another 11(3.15%) undetermined cases, totally 157(44.98%) cases with misdiagnosis; 116 ultrasound-guided CNB cases, 93(80.17%) cases with correct diagnosis compare with 19(16.37%) incorrect cases, and another 3(2.58%) undetermined cases, totally 22(18.96%) cases with misdiagnosis. The accuracy between FNA and ultrasound-guided CNB has significant difference.Preoperative ultrasound-guided CNB has significantly higher diagnostic value than FNA of thyroid malignant tumors.
引文
[1]Shrestha M,Crothers BA,Burch HB.The Impact of Thyroid Nodule Size on the Risk of Malignancy and Accuracy of Fine-needle Aspiration:A 10-year Study From a Single Institution[J].Thyroid,2012,22(12):1251-6.
    [2]Gilles Russ,Benedicte Royer,Claude Bigorgne,et al.Prospective Evaluation of Thyroid Imaging Reporting and Data System on4550 Nodules with and without Elastography[J].European Journal of Endocrinology 2013,168(5):649–55.
    [3]Cibas ES,Ali SZ.NCI Thyroid FNA State of the Science Conference.The Bethesda System for Reporting Thyroid Cytopathology[J].Am J Clin Pathol,2009,132(5):658-65.
    [4]章春来,陈丽丹,张箐菁,等.甲状腺结节细针穿刺细胞学检查影响涂片质量因素探讨[J].中国超声医学杂志,2014,30(10):871-873.
    [5]邬宏恂,张冰洁,臧亚萍,等.甲状腺结节超声引导下细针抽吸细胞学无法诊断结果的影响因素分析[J].临床超声医学杂志,2014,(08):523-526.
    [6]American Thyriod Association(ATA)Guidelines Taskforce on Thyriod Nodules and Differentiated Thyriod Cancer,Cooper DS,Doherty GM,et al.Revised American Thyroid Association Management Guidelines for Patients With Thyroid Nodules and Differentiated Thyroid Cancer[J].Thyroid,2009,19(11):1167-214.
    [7]纪小龙,吉米,主编.甲状腺病理诊断:6-9.北京,人民军医出版社,2011年第一版.ISBN:978-7-5091-4495-4
    [8]严佳梅,黄品同,游向东,等.超声造影结合细针穿刺对甲状腺癌的诊断价值[J].中华超声影像学杂志,2014,23(03):222-226.
    [9]Renshaw AA.Sensitivity of Fine-needle Aspiration for Papillary carcinoma of the thyroid correlates with tumor size[J].Diagn Cytopathol,2011,39(7):471-4.

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