The effects of Chitosan oligosaccharide on the activation of murine spleen CD11c~+ dendritic cells via Toll-like receptor 4
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- 英文论文题名：The effects of Chitosan oligosaccharide on the activation of murine spleen CD11c~+ dendritic cells via Toll-like receptor 4
- 论文作者：Yibing Dang ; Sheng Li ; Wenxia Wang ; Shujing Wang ; Mingming Zou ; Yanjie Guo ; Jianhui Fan ; Yuguang Du ; Jianing Zhang
- 英文论文作者：Yibing Dang ; Sheng Li ; Wenxia Wang ; Shujing Wang ; Mingming Zou ; Yanjie Guo ; Jianhui Fan ; Yuguang Du ; Jianing Zhang ; Department of Biochemistry ; Institute of Glycobiology ; Dalian Medical University ; Department of Biotechnology ; Dalian Institute of Chemical Physics ; CAS ; School of Life Science and Medicine ; Dalian University of Technology
- 年：2016
- 作者机构：Department of Biochemistry, Institute of Glycobiology, Dalian Medical University;Department of Biotechnology, Dalian Institute of Chemical Physics, CAS;School of Life Science and Medicine, Dalian University of Technology;
- 英文论文关键词：Chitosan oligosaccharide ; Spleen dendritic cell ; TLR4 ; immune response
- 会议召开时间：2016-10-20
- 会议录名称：中国化学会·2016全国多糖研讨会论文摘要集
- 英文会议录名称：Proceedings of 2016 China Polysaccharide Conference
- 语种：英文
- 分类号：O629.1;R392
- 学会代码：ZGHY
- 会议名称：中国化学会·2016全国多糖研讨会
- 会议地点：中国上海
- 主办单位：中国化学会
- 学会名称：中国化学会
- 页数：1
- 文件大小：352k
- 原文格式：D
- 会议级别：全国
摘要
<正>To investigate the effects of chitosan oligosaccharide(COS)on dendritic cells(DCs)and the role of Toll-like receptor 4(TLR4)in this immune process,Murine spleen CD11c+dendritic cells(SDCs)were isolated and cultured with S-COS and B-COS with polymeration degree of 3-7 and7-16,respectively.The results showed that B-COS up-regulated the expressions of MHCII and CD86 on SDCs,promoted the secretion of TNF-αfrom SDCs.SDCs treated with B-COS
引文
Yibing Dang,Sheng Li,Wenxia Wang,Shujing Wang,Mingming Zou,Yanjie Guo,Jianhui Fan,Yuguang Du,Jianing Zhang(2011)The effects of chitosan oligosaccharide on the activation of murine spleen CD11c+dendritic cells via Toll-like receptor 4.Carbohydrate Polymers83,1075-1081