曲美他嗪对冠心病(CHD)稳定性劳力型心绞痛患者心肌缺血的影响体会
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- 论文作者：白艳君
- 年：2016
- 作者机构：陕西省榆林市府谷县人民医院心内科;
- 论文关键词：曲美他嗪 ; 冠心病(CHD) ; 稳定性劳力型心绞痛患者 ; 心肌缺血 ; 影响
- 英文论文关键词：trimetazidine ; Coronary heart disease(CHD) ; The stability of Labour angina patients ; Myocardial ischemia ; impact
- 会议召开时间：2016-11-25
- 会议录名称：湖南中医药大学学报2016/专集：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会论文集
- 语种：中文
- 分类号：R541.4;R542.2
- 学会代码：HNZY
- 会议名称：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会
- 会议地点：中国广东珠海
- 主办单位：国际数字医学会、Digital Chinese Medicine
- 学会名称：湖南中医药大学期刊杂志社
- 页数：1
- 文件大小：2015k
- 原文格式：D
- 会议级别：全国
摘要
目的:研究曲美他嗪对冠心病(CHD)稳定性劳力型心绞痛患者心肌缺血的影响。方法:病例资料来源于我院2014年3月-2015年12月就诊的74例CHD稳定性劳力型心绞痛患者。随机分组方法:随机数字表法。74例患者分为常规组和曲美他嗪组。常规组给予传统常规疗法;曲美他嗪组加用曲美他嗪治疗。比较(1)不良反应发生率;(2)干预前和干预后患者心绞痛发作频率、运动诱发心绞痛时间、运动后ST段降低1毫米时间、硝酸甘油片用量的差异。结果:(1)曲美他嗪组、常规组仅有个别患者出现轻微失眠、乏力和头痛,P>0.05;(2)干预前两组心绞痛发作频率、运动诱发心绞痛时间、运动后ST段降低1毫米时间、硝酸甘油片用量相似,P>0.05;干预后曲美他嗪组对比常规组心绞痛发作频率、运动诱发心绞痛时间、运动后ST段降低1毫米时间、硝酸甘油片用量改善更显著,P<0.05。结论:曲美他嗪对CHD稳定性劳力型心绞痛患者心肌缺血的影响大,可有效改善患者临床症状,控制心绞痛发作,减少硝酸甘油片用量,安全可靠,值得推广。
objective: to study the stability of trimetazidine on coronary heart disease(CHD) Labour angina patients with myocardial ischemia. Methods: the clinical data from our hospitalin March 2014- December 2015 of 74 cases of CHD patients with stable Labour angina. Randomized approach: random number table approach. 74 patients were divided into normal group and thetrimetazidine group. Conventional traditional group was given routine therapy; Trimetazidine group treated with trimetazidine.(1) the incidence of adverse reactions;(2) the intervention before and afterintervention in patients with angina frequency and exercise induced angina ST segment to reduce 1 mm time after time, motion, the differences between the dosage of nitroglycerin tablets. Results:(1) thetrimetazidine group, conventional group only mild insomnia, fatigue and headaches, individual patients(P > 0.05;(2) the exercise frequency of angina pectoris attack, the two groups before interventioninduce angina ST segment to reduce 1 mm time after time, motion, the dosage of nitroglycerin tablets, P > 0.05; Trimetazidine after the intervention group compared to conventional angina frequency andexercise induced angina ST segment to reduce 1 mm time after time, motion, the dosage of nitroglycerin tablets improved more significantly, P < 0.05). Conclusion: trimetazidine myocardial ischemia inpatients with CHD stability Labour angina influence is big, which can effectively improve the patients' clinical symptoms, control angina pectoris attack, reduce the dosage of nitroglycerin tablets, safeand reliable, is worth promoting.
objective: to study the stability of trimetazidine on coronary heart disease(CHD) Labour angina patients with myocardial ischemia. Methods: the clinical data from our hospitalin March 2014- December 2015 of 74 cases of CHD patients with stable Labour angina. Randomized approach: random number table approach. 74 patients were divided into normal group and thetrimetazidine group. Conventional traditional group was given routine therapy; Trimetazidine group treated with trimetazidine.(1) the incidence of adverse reactions;(2) the intervention before and afterintervention in patients with angina frequency and exercise induced angina ST segment to reduce 1 mm time after time, motion, the differences between the dosage of nitroglycerin tablets. Results:(1) thetrimetazidine group, conventional group only mild insomnia, fatigue and headaches, individual patients(P > 0.05;(2) the exercise frequency of angina pectoris attack, the two groups before interventioninduce angina ST segment to reduce 1 mm time after time, motion, the dosage of nitroglycerin tablets, P > 0.05; Trimetazidine after the intervention group compared to conventional angina frequency andexercise induced angina ST segment to reduce 1 mm time after time, motion, the dosage of nitroglycerin tablets improved more significantly, P < 0.05). Conclusion: trimetazidine myocardial ischemia inpatients with CHD stability Labour angina influence is big, which can effectively improve the patients' clinical symptoms, control angina pectoris attack, reduce the dosage of nitroglycerin tablets, safeand reliable, is worth promoting.
引文
[1]吴奇志.曲美他嗪对冠心病稳定性劳力型心绞痛患者心肌缺血的影响[J].中国临床实用医学,2010,04(1):66-67.
[2]李雪冬,丁坤,孙春启等.曲美他嗪对冠心病稳定性劳力型心绞痛患者心肌缺血的影响[J].医药前沿,2013,24(31):238-239.
[3]王长城,朱华峰.中西医结合治疗冠心病心绞痛的临床研究[J].现代中西医结合杂志,2013,22(23):2552-2553.
[4]王真,丁坤,孙春启等.曲美他嗪治疗冠心病稳定性劳力型心绞痛的临床疗效观察[J].中国保健营养(中旬刊),2014,13(6):3778-3779.
[5]陈琦,周亚峰,杨向军等.曲美他嗪对稳定性劳力型心绞痛患者运动耐量的影响[J].山东医药,2010,50(40):85-87.
[6]董汉卿,刘中奇.曲美他嗪与硝酸异山梨酯治疗稳定性劳力型心绞痛的疗效观察[J].临床医药文献电子杂志,2015,22(6):1154-1154,1155.
[7]陆淑凤.曲美他嗪与硝酸异山梨酯治疗稳定性劳力型心绞痛效果比较[J].中外医疗,2015,31(12):87-88.
[8]陈彪.硝酸异山梨酯和曲美他嗪治疗稳定性劳力型心绞痛的临床观察[J].中国继续医学教育,2015,17(21):167-168.
[2]李雪冬,丁坤,孙春启等.曲美他嗪对冠心病稳定性劳力型心绞痛患者心肌缺血的影响[J].医药前沿,2013,24(31):238-239.
[3]王长城,朱华峰.中西医结合治疗冠心病心绞痛的临床研究[J].现代中西医结合杂志,2013,22(23):2552-2553.
[4]王真,丁坤,孙春启等.曲美他嗪治疗冠心病稳定性劳力型心绞痛的临床疗效观察[J].中国保健营养(中旬刊),2014,13(6):3778-3779.
[5]陈琦,周亚峰,杨向军等.曲美他嗪对稳定性劳力型心绞痛患者运动耐量的影响[J].山东医药,2010,50(40):85-87.
[6]董汉卿,刘中奇.曲美他嗪与硝酸异山梨酯治疗稳定性劳力型心绞痛的疗效观察[J].临床医药文献电子杂志,2015,22(6):1154-1154,1155.
[7]陆淑凤.曲美他嗪与硝酸异山梨酯治疗稳定性劳力型心绞痛效果比较[J].中外医疗,2015,31(12):87-88.
[8]陈彪.硝酸异山梨酯和曲美他嗪治疗稳定性劳力型心绞痛的临床观察[J].中国继续医学教育,2015,17(21):167-168.