Myeloid STAT3 promotes hepatocarcinogenesis by inactivating natural killer T cells
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- 英文论文题名：Myeloid STAT3 promotes hepatocarcinogenesis by inactivating natural killer T cells
- 论文作者：wang hua ; Yin Shi ; Li Jun ; Gao Bin
- 英文论文作者：wang hua ; Yin Shi ; Li Jun ; Gao Bin ; Department of Oncology ; The First Affiliated Hospital of Anhui Medical University ; NIAAA ; National Institutes of Health ; Department of Geriatrics ; Affiliated Provincial Hospital of Anhui Medical University ; Institute for Liver Diseases ; Anhui Medical University
- 年：2016
- 作者机构：Department of Oncology, The First Affiliated Hospital of Anhui Medical University;NIAAA, National Institutes of Health;Department of Geriatrics,Affiliated Provincial Hospital of Anhui Medical University;Institute for Liver Diseases, Anhui Medical University;
- 英文论文关键词：Myeloid cells ; STAT3 ; hepatocarcinogenesis ; natural killer T cells
- 会议召开时间：2016-11-04
- 会议录名称：第十一届全国免疫学学术大会分会场交流报告集
- 英文会议录名称：Proceedings of 2016 CSI Congress on Immunology
- 语种：英文
- 分类号：R735.7
- 学会代码：IGMD
- 会议名称：第十一届全国免疫学学术大会
- 会议地点：中国安徽合肥
- 主办单位：中国免疫学会
- 学会名称：中国免疫学会
- 页数：1
- 文件大小：254k
- 原文格式：D
- 会议级别：全国
摘要
<正>Background/objectives:Activation of signal transducer and activator of transcription 3(STAT3)occurs virtually in most liver diseases,but how STAT3 links liver inflammation and cancer remains elusive.Methods and results:Using cell-specific STAT3 deletions mouse strains,we have investigated the interplay of myeloid and hepatic STAT3 in controlling hepatocarcinogenesis induced by diethylinitrosamine(DEN).We show that
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