环境污染对皮肤损伤机理及测试方法探讨
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- 英文论文题名：The Mechanism of Environmental Pollution Impacts on Skin and the Testing Method
- 论文作者：赵小敏 ; 赵云珊 ; 瞿欣
- 英文论文作者：Zhao Xiaomin ; Zhao Yunshan ; Qu Xin ; Ashland(China) Inc. ; Shanghai Technical Center
- 年：2016
- 作者机构：亚什兰(中国)投资有限公司上海技术中心;
- 论文关键词：环境污染 ; PM2.5 ; 粉红胡椒树提取物
- 英文论文关键词：Environmental pollutants ; PM2 ; 5 ; Pink pepper extract
- 会议召开时间：2016-06-15
- 会议录名称：第十一届中国化妆品学术研讨会论文集
- 英文会议录名称：The Proceedings of the 11th Seminar on Cosmetic China
- 语种：中文
- 分类号：R99
- 学会代码：ZGXE
- 会议名称：第十一届中国化妆品学术研讨会
- 会议地点：中国上海
- 主办单位：中国香料香精化妆品工业协会
- 学会名称：中国香料香精化妆品工业协会
- 页数：8
- 文件大小：560k
- 原文格式：O
- 会议级别：全国
摘要
通过整理和总结多篇文献,综合分析和论述了环境污染尤其是PM2.5颗粒对皮肤的损伤机理。同时通过对粉红胡椒树提取物Elixiance的研究,探讨了如何建立合理的针对性的方法,来研究污染对皮肤的伤害,及活性物对皮肤损伤的修复,并对基于损伤的机理提出一些解决方案。研究结果显示,污染对皮肤的损伤是全方位的,研究污染对皮肤的损伤需要建立合理的针对性的方法模型进行研究,对抗污染的产品应具备多方面的防护和修复特性。
Recent articles are reviewed to discuss the molecular damaging pathway of various pollutants especially PM2.5 particles.By studying the anti-pollution effect of pink pepper extract in-vitro and ex-vivo,how to set up reasonable and efficient methodology is discussed.Finally,the anti-pollution solutions based on the pollutants acting mechanism are discussed.The results showed that pollutants harm our skin by various pathways,it's really import to set up various method to study anti-pollution effect and have a package solution to fight against it.
Recent articles are reviewed to discuss the molecular damaging pathway of various pollutants especially PM2.5 particles.By studying the anti-pollution effect of pink pepper extract in-vitro and ex-vivo,how to set up reasonable and efficient methodology is discussed.Finally,the anti-pollution solutions based on the pollutants acting mechanism are discussed.The results showed that pollutants harm our skin by various pathways,it's really import to set up various method to study anti-pollution effect and have a package solution to fight against it.
引文
[1].Li Miaozhu,Vierkotter A,Schikowski T,etc,Epidemiological evidence that indoor air pollution from cooking with solid fuels accelerates skin aging in Chinese women[J].Journal of Dermatological science,2015,79:148-154.
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[3].VierkOtter A,Schikowski T.Ranti U,etc.Airborne particle exposure and extrinsic skin aging[J].Journal of Investigative Dermatology,2010,130(12):2719-2726.
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[5].Krutmann J,Liu W,Li L,etc,Pollution and skin:From epidemiological and mechanistic studies to clinical implications[J].Journal of Dermatological Science,2014,76:163-168.
[6].Drakaki E,Dessinioti C,Antoniou V.C,air pollution and the skin[J].Frontiers in environmental science,2014,2:1-6
[7].Abel J,Haarmann-Stemmann T,An introduction to the molecular basics of aryl hydrocarbon receptor biology[J].Biology Chemistry,2010,391:1235-1248.
[8].Tigges J,Haarmann-stammann T,Vogel F.A.C,etc,The new aryl hydrocarbon receptor antagonist E/Z-2-Benzylindene-5,6-Dimethoxy-3,3-Dimethylindan-1-one protects against UVB-induced signal transduction[J].Journal of Investigative Dermatology,2014,134(2):556-559
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[10].Pham D.M,Boussouira B,Moyal D,etc,Oxidation of squalene,a human skin lipid:a new and reliable marker of environmental pollution studies[J].International journal of cosmetic science,2015,37:357-365.
[11].Lefebvre A.M,Pham,M.D,Boussouira B,Evaluation of the impact of urban pollution on the quality of skin:a multicentre study in Mexico[J].International Journal of cosmetic science,2015,37:329-338.
[12].Iwai.I,Hirao.T,Protein carbonyls damage the water-holding capacity of the stratum corneum[J],skin pharmacology and physiology,2008,21:269-273.
[13].Iwai.I,Murayama K.I,Hirao T,Change in optical properties of stratum corneum induced by protein carbonylation in vitro[J].International Journal of Cosmetic Science,2008,30:41-46.
[14].Iwai.I,Kuwahara T,Hirao.T,Decrease in the skin transparency induced by protein carbonylation in the stratum corneum[J].International Journal of Cosmetic Science,2008,42(1):16-21.
[15].Ramos-Gomez M,Kwak MK,Dolan PM,etc,Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice[J].Proceedings of the National Acadamy of Sciences of the United States of America,2001,98(6):3410-5.
[16].王秀君,李欣,唐修文,Nrf2通路在肿瘤化学预防中的研究进展[J],化学进展,2013,25(9):1544~1552.
[17].Talhout R,Schulz T,Florek E,etc,Hazardous compounds in tobacco smoke[J],International journal of environmental research,2011,8:613-628.
[18].Gkogkolou P,Bohm M,Advanced glycation end products,key players in skin aging?,Dermato-endocrinology,2012,4(3):259-270.
[19].Plantivaux A,Bauza E,Marchand T,etc,Protecting skin from UV oxidative stress with a new(Cys-Gly)2 dimer peptide[J],cosmetics&Toiletries,2007,122(1):45-51.
[20].Cucumel K,Domloge R,Skin-protecting dinucleotide examined[J],Personal care,2008,1:25-28.
[21].Imbert I,Gondran C,Oberto G,etc,Maintenance of ubiquitin-proteasome system activity correlates with visible skin benefits[J],International Journal of cosmetic science,2010,1-11.
[22].Ando H,Ichihashi M,Hearing J.V,Role of the ubiquitin proteasome systems in regulating skin pigmentation,International journal of molecular science,2009,10:4428-4434.
[23].瞿欣,赵小敏,赵云珊等,ProlixirICE&Stratixyl发现简单而美好的健康肌肤,千色美业,2014,1:15-18.
[2].甄雅贤,刘玮,环境污染与皮肤健康[J].中华皮肤科杂志,2015,48(1):67~70.
[3].VierkOtter A,Schikowski T.Ranti U,etc.Airborne particle exposure and extrinsic skin aging[J].Journal of Investigative Dermatology,2010,130(12):2719-2726.
[4].Valacchi G,Sticozzi C,Pecorelli A,etc,Cutaneous responses to environmental stressors[J].Annals of the new York academy of sciences,2012,1271:75-81.
[5].Krutmann J,Liu W,Li L,etc,Pollution and skin:From epidemiological and mechanistic studies to clinical implications[J].Journal of Dermatological Science,2014,76:163-168.
[6].Drakaki E,Dessinioti C,Antoniou V.C,air pollution and the skin[J].Frontiers in environmental science,2014,2:1-6
[7].Abel J,Haarmann-Stemmann T,An introduction to the molecular basics of aryl hydrocarbon receptor biology[J].Biology Chemistry,2010,391:1235-1248.
[8].Tigges J,Haarmann-stammann T,Vogel F.A.C,etc,The new aryl hydrocarbon receptor antagonist E/Z-2-Benzylindene-5,6-Dimethoxy-3,3-Dimethylindan-1-one protects against UVB-induced signal transduction[J].Journal of Investigative Dermatology,2014,134(2):556-559
[9].Ayala A,Munoz F M,Arguelles S,Lipid peroxidation:production,metabolism,and signaling mechanisms of malondialdehyde and4-hydroxy-2-Nonenal[J].Oxidative medicine and cellular longevity,2014,1-31.
[10].Pham D.M,Boussouira B,Moyal D,etc,Oxidation of squalene,a human skin lipid:a new and reliable marker of environmental pollution studies[J].International journal of cosmetic science,2015,37:357-365.
[11].Lefebvre A.M,Pham,M.D,Boussouira B,Evaluation of the impact of urban pollution on the quality of skin:a multicentre study in Mexico[J].International Journal of cosmetic science,2015,37:329-338.
[12].Iwai.I,Hirao.T,Protein carbonyls damage the water-holding capacity of the stratum corneum[J],skin pharmacology and physiology,2008,21:269-273.
[13].Iwai.I,Murayama K.I,Hirao T,Change in optical properties of stratum corneum induced by protein carbonylation in vitro[J].International Journal of Cosmetic Science,2008,30:41-46.
[14].Iwai.I,Kuwahara T,Hirao.T,Decrease in the skin transparency induced by protein carbonylation in the stratum corneum[J].International Journal of Cosmetic Science,2008,42(1):16-21.
[15].Ramos-Gomez M,Kwak MK,Dolan PM,etc,Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice[J].Proceedings of the National Acadamy of Sciences of the United States of America,2001,98(6):3410-5.
[16].王秀君,李欣,唐修文,Nrf2通路在肿瘤化学预防中的研究进展[J],化学进展,2013,25(9):1544~1552.
[17].Talhout R,Schulz T,Florek E,etc,Hazardous compounds in tobacco smoke[J],International journal of environmental research,2011,8:613-628.
[18].Gkogkolou P,Bohm M,Advanced glycation end products,key players in skin aging?,Dermato-endocrinology,2012,4(3):259-270.
[19].Plantivaux A,Bauza E,Marchand T,etc,Protecting skin from UV oxidative stress with a new(Cys-Gly)2 dimer peptide[J],cosmetics&Toiletries,2007,122(1):45-51.
[20].Cucumel K,Domloge R,Skin-protecting dinucleotide examined[J],Personal care,2008,1:25-28.
[21].Imbert I,Gondran C,Oberto G,etc,Maintenance of ubiquitin-proteasome system activity correlates with visible skin benefits[J],International Journal of cosmetic science,2010,1-11.
[22].Ando H,Ichihashi M,Hearing J.V,Role of the ubiquitin proteasome systems in regulating skin pigmentation,International journal of molecular science,2009,10:4428-4434.
[23].瞿欣,赵小敏,赵云珊等,ProlixirICE&Stratixyl发现简单而美好的健康肌肤,千色美业,2014,1:15-18.