Utility of A Type Ⅲ Portable Monitor for Diagnosis of OSA
详细信息 查看官网全文
- 英文论文题名：Utility of A Type Ⅲ Portable Monitor for Diagnosis of OSA
- 论文作者：Liyue Xu ; Samuel Kuna ; Allan Pack ; Brendan Keenan ; Elizabeth Kneeland ; Yuan Chang ; Xiaosong Dong ; Jing Li ; Wei Zhang ; Long Zhao ; Pei An ; Xueli Zhang ; Fang Han
- 英文论文作者：Liyue Xu ; Samuel Kuna ; Allan Pack ; Brendan Keenan ; Elizabeth Kneeland ; Yuan Chang ; Xiaosong Dong ; Jing Li ; Wei Zhang ; Long Zhao ; Pei An ; Xueli Zhang ; Fang Han ; PKU-UPenn Sleep Center ; Peking University International Hospital ; Penn Center for Sleep ; University of Pennsylvania ; Department of Pulmonary Medicine ; Peking University People's Hospital
- 年：2016
- 作者机构：PKU-UPenn Sleep Center,Peking University International Hospital;Penn Center for Sleep,University of Pennsylvania;Department of Pulmonary Medicine,Peking University People's Hospital;
- 英文论文关键词：type Ⅲ Portable monitor ; Validation ; NOX T3 ; Home sleep test
- 会议召开时间：2016-05-27
- 会议录名称：中国睡眠研究会第九届学术年会汇编
- 语种：英文
- 分类号：R766
- 学会代码：OGSF
- 会议名称：中国睡眠研究会第九届学术年会
- 会议地点：中国上海
- 主办单位：中国睡眠研究会
- 学会名称：中国睡眠研究会
- 页数：2
- 文件大小：66k
- 原文格式：O
- 会议级别：全国
摘要
Study Objectives:This study aims to compare NOX T3 study at-home to in-lab polysomnogram and simultaneous NOX T3 study.Secondly,we aim to compare the diagnostic accuracy of the NOX T3 portable sleep monitor to that of simultaneously recorded in-lab polysomnogram(PSG) in adults being evaluated for obstructive sleep apnea(OSA).Methods:A total of 81 participants were recruited following face-to-face evaluation at PKU People's hospital'ssleep center.All participants initially performed an overnight HST using the Nox-T3 portable monitor.Within 2 weeks of the HST,participants performed an in-laboratory PSG with a simultaneous Nox-T3 portable monitor recording.PSG records were manually scored using the American Academy of Sleep Medicine(AASM) criteria,and PM records were double-scored using the device's autoscore algorithm as well as manual scoring.Two separate manually edited scorings were performed using different definitions for hypopnea in both HST and PSG,1) events with ≥ 30%reduction in airflow from baseline for≥ 10 seconds accompanied by ≥4%oxygen desaturation,and2)events with ≥30%reduction in airflow from baseline for ≥10 seconds associated with≥3%reduction in oxygen saturation and/(or an arousal in PSG).The ability of subjects to perform HST was assessed as the percentage of successful HST on first and second recording attempts and HST quality.Results:The final sample consisted of 81 participants(63 males,18 females) with a mean ± SD age,ESS,BMI,of 47.65±13.98,10.28±5.11,27.55±5.45Kg/m~2.Successful rate for 1~(st) HST and 2~(nd) NOX study in lab was 93.75%(75/80),95%(76/80).No one failed in second time's home study when the first time of HST failed.And average apnea-hypopnea index ±SD(AHI 3%oxygen desaturation for hypopnea) in 1~(st) NOX,2~(nd) NOX and PSGwas 28.54±20.35/h,32.54±22.39/h,33.51±23.2/h.Manual score-derived T3 AHI(3%) and PSG-derived AHI(3%) were strongly related(r=.92).The T3(manualscored AHI) demonstrated a high degree of sensitivity for the presence of obstructive sleep apnea syndrome(OSA;100%) and highspecificity for the diagnosis of OSA when AHI≥5 events/h(93.15%).The unit(manualscored) had a high degree of both sensitivity(95.83%) and specificity(83.3%) when the presence of OSA was defined more conservatively(AHI > 15 events/h).The unit(manualscored) had a high degree of both sensitivity(97.56%) and specificity(86.49%) when the presence of severe OSA was defined as AHI >30 events/h.Conclusions:ln this clinic-based sample,this type Ⅲ portable monitor demonstrated to be easy for patients to complete the HST.And it is very good measurement agreement compared to PSG and a high degree of sensitivity and specificity for detecting OSA including mild,moderate and severe OSA.
Study Objectives:This study aims to compare NOX T3 study at-home to in-lab polysomnogram and simultaneous NOX T3 study.Secondly,we aim to compare the diagnostic accuracy of the NOX T3 portable sleep monitor to that of simultaneously recorded in-lab polysomnogram(PSG) in adults being evaluated for obstructive sleep apnea(OSA).Methods:A total of 81 participants were recruited following face-to-face evaluation at PKU People's hospital'ssleep center.All participants initially performed an overnight HST using the Nox-T3 portable monitor.Within 2 weeks of the HST,participants performed an in-laboratory PSG with a simultaneous Nox-T3 portable monitor recording.PSG records were manually scored using the American Academy of Sleep Medicine(AASM) criteria,and PM records were double-scored using the device's autoscore algorithm as well as manual scoring.Two separate manually edited scorings were performed using different definitions for hypopnea in both HST and PSG,1) events with ≥ 30%reduction in airflow from baseline for≥ 10 seconds accompanied by ≥4%oxygen desaturation,and2)events with ≥30%reduction in airflow from baseline for ≥10 seconds associated with≥3%reduction in oxygen saturation and/(or an arousal in PSG).The ability of subjects to perform HST was assessed as the percentage of successful HST on first and second recording attempts and HST quality.Results:The final sample consisted of 81 participants(63 males,18 females) with a mean ± SD age,ESS,BMI,of 47.65±13.98,10.28±5.11,27.55±5.45Kg/m~2.Successful rate for 1~(st) HST and 2~(nd) NOX study in lab was 93.75%(75/80),95%(76/80).No one failed in second time's home study when the first time of HST failed.And average apnea-hypopnea index ±SD(AHI 3%oxygen desaturation for hypopnea) in 1~(st) NOX,2~(nd) NOX and PSGwas 28.54±20.35/h,32.54±22.39/h,33.51±23.2/h.Manual score-derived T3 AHI(3%) and PSG-derived AHI(3%) were strongly related(r=.92).The T3(manualscored AHI) demonstrated a high degree of sensitivity for the presence of obstructive sleep apnea syndrome(OSA;100%) and highspecificity for the diagnosis of OSA when AHI≥5 events/h(93.15%).The unit(manualscored) had a high degree of both sensitivity(95.83%) and specificity(83.3%) when the presence of OSA was defined more conservatively(AHI > 15 events/h).The unit(manualscored) had a high degree of both sensitivity(97.56%) and specificity(86.49%) when the presence of severe OSA was defined as AHI >30 events/h.Conclusions:ln this clinic-based sample,this type Ⅲ portable monitor demonstrated to be easy for patients to complete the HST.And it is very good measurement agreement compared to PSG and a high degree of sensitivity and specificity for detecting OSA including mild,moderate and severe OSA.
Study Objectives:This study aims to compare NOX T3 study at-home to in-lab polysomnogram and simultaneous NOX T3 study.Secondly,we aim to compare the diagnostic accuracy of the NOX T3 portable sleep monitor to that of simultaneously recorded in-lab polysomnogram(PSG) in adults being evaluated for obstructive sleep apnea(OSA).Methods:A total of 81 participants were recruited following face-to-face evaluation at PKU People's hospital'ssleep center.All participants initially performed an overnight HST using the Nox-T3 portable monitor.Within 2 weeks of the HST,participants performed an in-laboratory PSG with a simultaneous Nox-T3 portable monitor recording.PSG records were manually scored using the American Academy of Sleep Medicine(AASM) criteria,and PM records were double-scored using the device's autoscore algorithm as well as manual scoring.Two separate manually edited scorings were performed using different definitions for hypopnea in both HST and PSG,1) events with ≥ 30%reduction in airflow from baseline for≥ 10 seconds accompanied by ≥4%oxygen desaturation,and2)events with ≥30%reduction in airflow from baseline for ≥10 seconds associated with≥3%reduction in oxygen saturation and/(or an arousal in PSG).The ability of subjects to perform HST was assessed as the percentage of successful HST on first and second recording attempts and HST quality.Results:The final sample consisted of 81 participants(63 males,18 females) with a mean ± SD age,ESS,BMI,of 47.65±13.98,10.28±5.11,27.55±5.45Kg/m~2.Successful rate for 1~(st) HST and 2~(nd) NOX study in lab was 93.75%(75/80),95%(76/80).No one failed in second time's home study when the first time of HST failed.And average apnea-hypopnea index ±SD(AHI 3%oxygen desaturation for hypopnea) in 1~(st) NOX,2~(nd) NOX and PSGwas 28.54±20.35/h,32.54±22.39/h,33.51±23.2/h.Manual score-derived T3 AHI(3%) and PSG-derived AHI(3%) were strongly related(r=.92).The T3(manualscored AHI) demonstrated a high degree of sensitivity for the presence of obstructive sleep apnea syndrome(OSA;100%) and highspecificity for the diagnosis of OSA when AHI≥5 events/h(93.15%).The unit(manualscored) had a high degree of both sensitivity(95.83%) and specificity(83.3%) when the presence of OSA was defined more conservatively(AHI > 15 events/h).The unit(manualscored) had a high degree of both sensitivity(97.56%) and specificity(86.49%) when the presence of severe OSA was defined as AHI >30 events/h.Conclusions:ln this clinic-based sample,this type Ⅲ portable monitor demonstrated to be easy for patients to complete the HST.And it is very good measurement agreement compared to PSG and a high degree of sensitivity and specificity for detecting OSA including mild,moderate and severe OSA.
引文