A review of virulence associated genes and their coding proteins of the Cryptosporidium
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- 英文论文题名：A review of virulence associated genes and their coding proteins of the Cryptosporidium
- 论文作者：Liu Zhenzhen
- 英文论文作者：Liu Zhenzhen ; Henan Agricultural University
- 年：2016
- 作者机构：Henan Agricultural University;
- 英文论文关键词：Cryptosporidium ; virulence associated gene ; coding protein ; application
- 会议召开时间：2016-11-04
- 会议录名称：第十一届全国免疫学学术大会摘要汇编
- 英文会议录名称：Abstracts of 2016 CSI Congress on Immunology
- 语种：英文
- 分类号：R383.3
- 学会代码：IGMD
- 会议名称：第十一届全国免疫学学术大会
- 会议地点：中国安徽合肥
- 主办单位：中国免疫学会
- 学会名称：中国免疫学会
- 页数：1
- 文件大小：1262k
- 原文格式：D
- 会议级别：全国
摘要
Cryptosporidium is a human and animal severe diarrhea apicomplexan parasitic protozoa, with worldwide distribution. The protozoa in the normal immune function is acute self limiting infection, but in immunocompromised patients and defect or inhibition, is a chronic persistent infection, which easily lead to diarrhea and even water severe dehydration and endanger life. Cryptosporidiosis seriously affect human and animal health, caused a great threat to human public health, there is no effective drugs can be used to prevent the current. The disease has been identified as one of the 6 largest cause of human diarrhea. The study shows that the effect of virulence related gene of Cryptosporidium and the encoding protein on the host, throughout the infection and the incidence stage. Therefore, to find the parasite host cell adhesion and invasion associated virulence genes and the encoding protein, Further to study its function has important significance on the prevention and treatment of cryptosporidiosis drugs and vaccines development. It has been speculated that more than 25 kinds of virulence factors are related to the invasion and adhesion of the Cryptosporidium, so the identification of the function of these virulence related factors is essential for the development of vaccines or effective prevention and treatment of drugs.This paper reviews the Cryptosporidium virulence gene and its encoding protein used to cryptosporidiosis provide new ideas and tools of prevention and vaccine development.
Cryptosporidium is a human and animal severe diarrhea apicomplexan parasitic protozoa, with worldwide distribution. The protozoa in the normal immune function is acute self limiting infection, but in immunocompromised patients and defect or inhibition, is a chronic persistent infection, which easily lead to diarrhea and even water severe dehydration and endanger life. Cryptosporidiosis seriously affect human and animal health, caused a great threat to human public health, there is no effective drugs can be used to prevent the current. The disease has been identified as one of the 6 largest cause of human diarrhea. The study shows that the effect of virulence related gene of Cryptosporidium and the encoding protein on the host, throughout the infection and the incidence stage. Therefore, to find the parasite host cell adhesion and invasion associated virulence genes and the encoding protein, Further to study its function has important significance on the prevention and treatment of cryptosporidiosis drugs and vaccines development. It has been speculated that more than 25 kinds of virulence factors are related to the invasion and adhesion of the Cryptosporidium, so the identification of the function of these virulence related factors is essential for the development of vaccines or effective prevention and treatment of drugs.This paper reviews the Cryptosporidium virulence gene and its encoding protein used to cryptosporidiosis provide new ideas and tools of prevention and vaccine development.
Cryptosporidium is a human and animal severe diarrhea apicomplexan parasitic protozoa, with worldwide distribution. The protozoa in the normal immune function is acute self limiting infection, but in immunocompromised patients and defect or inhibition, is a chronic persistent infection, which easily lead to diarrhea and even water severe dehydration and endanger life. Cryptosporidiosis seriously affect human and animal health, caused a great threat to human public health, there is no effective drugs can be used to prevent the current. The disease has been identified as one of the 6 largest cause of human diarrhea. The study shows that the effect of virulence related gene of Cryptosporidium and the encoding protein on the host, throughout the infection and the incidence stage. Therefore, to find the parasite host cell adhesion and invasion associated virulence genes and the encoding protein, Further to study its function has important significance on the prevention and treatment of cryptosporidiosis drugs and vaccines development. It has been speculated that more than 25 kinds of virulence factors are related to the invasion and adhesion of the Cryptosporidium, so the identification of the function of these virulence related factors is essential for the development of vaccines or effective prevention and treatment of drugs.This paper reviews the Cryptosporidium virulence gene and its encoding protein used to cryptosporidiosis provide new ideas and tools of prevention and vaccine development.
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