ESC-3 induces apoptosis of human ovarian carcinomas through Wnt/β-catenin and Notch signaling
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- 英文论文题名：ESC-3 induces apoptosis of human ovarian carcinomas through Wnt/β-catenin and Notch signaling
- 论文作者：Qi-Rui Fu ; Yi-Tao Deng ; Hua-Liang Li ; Xiao-Mei Mao ; Chen-Lu Lin ; Ya-Hui Zheng ; Shu-Ming Chen ; Qiong-Hua Chen ; Qing-Xi Chen
- 英文论文作者：Qi-Rui Fu ; Yi-Tao Deng ; Hua-Liang Li ; Xiao-Mei Mao ; Chen-Lu Lin ; Ya-Hui Zheng ; Shu-Ming Chen ; Qiong-Hua Chen ; Qing-Xi Chen ; State Key Laboratory of Cellular Stress Biology ; Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystems ; School of Life Sciences ; Xiamen University ; The First Affiliated Hospital of Xiamen University
- 年：2016
- 作者机构：State Key Laboratory of Cellular Stress Biology,Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystems,School of Life Sciences,Xiamen University;The First Affiliated Hospital of Xiamen University;
- 英文论文关键词：ESC-3 ; apoptosis ; ovarian carcinomas ; xenograft models ; Notch signaling
- 会议召开时间：2016-09-01
- 会议录名称：全国农业生物化学与分子生物学第十五届学术研讨会会议文集
- 英文会议录名称：The Special Edition of the 15th National Symposium of Agricultural Biochemistry and Molecular Biology
- 语种：英文
- 分类号：R737.31
- 学会代码：IGSS
- 会议名称：全国农业生物化学与分子生物学第十五届学术研讨会
- 会议地点：中国甘肃兰州
- 主办单位：中国生物化学与分子生物学会农业分会
- 学会名称：中国生物化学与分子生物学会
- 页数：2
- 文件大小：469k
- 原文格式：O
- 会议级别：全国
摘要
<正>Methods:Cell viability was determined using the CCK-8 assay.To investigate the apoptosis mechanism induced by ESC-3,the expression of apoptosis-related(Bax,Bcl-2,P53)and pathway-related(Wnt2,β-catenin,notch1,notch2,Hes1)proteins were measured by Western blot and quantified using the Image J software.To determine the anti-tumor effects of ESC-3,1×106 A2780cells was injected subcutaneously into the right flank of Balb/c nude mice to build the tumor xenograft
引文