Validation of ESS,STOP,STOP-BANG questionnaire for identification of patients with OSAHS
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摘要
Objectives To evaluate the efficiency of ESS,STOP,STOP-BANG questionnaire in screening OSAHS in Shanghai and individually discuss the impact of gender on the screening.Methods Consecutive subjects referred for suspected OSAHS from October 2010 to January 2013 were included in this study.After excluding related diseases,all included adults completed a medical history inquiry,the ESS scale,STOP-BANG questionnaire,anthropometric measurements and overnight PSG.A prediction model based on STOP-BANG questionnaire and other variables was built.Receiver operating characteristic(ROC) curve analyses were used to estimate the efficiency of ESS,STOP,STOP-BANG questionnaires and prediction model in screening OSAHS.Furthermore,all analyses were stratified by sex to discuss the impact of gender on screening.Results A total of 1087 adults were included in the final analysis.Significant differences of ESS scale,STOP and STOP-BANG questionnaires in predicting OSAHS were found between OSAHS and nonOSAHS groups.ROC curve demonstrated that both STOP and STOP-BANG questionnaires had better diagnostic accuracy than ESS scale.For OSAHS with AHI >5,STOP-BANG questionnaire had an area under ROC curve(AUC) of 0.841(0.813-0.868),a sensitivity of 79.0%and specificity of 76.3%.The STOP-BANG based prediction model had an AUC of 0.920(0.900-0.937),a sensitivity of 78.0%and a specificity of 90.0%in males;an AUC of 0.942(0.912-0.971),a sensitivity of 95.0%and a specificity of 83.5%in females.In addition,analysis stratified by gender showed differences of best cut-off values between males and females in STOP-BANG questionnaire,which was 3 in males and 2 in females.Conclusions Both STOP and STOP-BANG questionnaires had moderate diagnostic accuracy for OSAHS.The STOP-BANG-based prediction model had excellent diagnostic efficiency,and could be applied to clinical use.Additionally,the best cut-off values differed from males to females,which should be considered in clinical practice.
Objectives To evaluate the efficiency of ESS,STOP,STOP-BANG questionnaire in screening OSAHS in Shanghai and individually discuss the impact of gender on the screening.Methods Consecutive subjects referred for suspected OSAHS from October 2010 to January 2013 were included in this study.After excluding related diseases,all included adults completed a medical history inquiry,the ESS scale,STOP-BANG questionnaire,anthropometric measurements and overnight PSG.A prediction model based on STOP-BANG questionnaire and other variables was built.Receiver operating characteristic(ROC) curve analyses were used to estimate the efficiency of ESS,STOP,STOP-BANG questionnaires and prediction model in screening OSAHS.Furthermore,all analyses were stratified by sex to discuss the impact of gender on screening.Results A total of 1087 adults were included in the final analysis.Significant differences of ESS scale,STOP and STOP-BANG questionnaires in predicting OSAHS were found between OSAHS and nonOSAHS groups.ROC curve demonstrated that both STOP and STOP-BANG questionnaires had better diagnostic accuracy than ESS scale.For OSAHS with AHI >5,STOP-BANG questionnaire had an area under ROC curve(AUC) of 0.841(0.813-0.868),a sensitivity of 79.0%and specificity of 76.3%.The STOP-BANG based prediction model had an AUC of 0.920(0.900-0.937),a sensitivity of 78.0%and a specificity of 90.0%in males;an AUC of 0.942(0.912-0.971),a sensitivity of 95.0%and a specificity of 83.5%in females.In addition,analysis stratified by gender showed differences of best cut-off values between males and females in STOP-BANG questionnaire,which was 3 in males and 2 in females.Conclusions Both STOP and STOP-BANG questionnaires had moderate diagnostic accuracy for OSAHS.The STOP-BANG-based prediction model had excellent diagnostic efficiency,and could be applied to clinical use.Additionally,the best cut-off values differed from males to females,which should be considered in clinical practice.
引文

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