Self-assembly of syntaxin-1A in model membrane explored by multiscale molecular dynamics simulation
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- 英文论文题名：Self-assembly of syntaxin-1A in model membrane explored by multiscale molecular dynamics simulation
- 论文作者：Jing Han ; Rainer A. B?ckmann ; Jie Ma
- 英文论文作者：Jing Han ; Rainer A. B?ckmann ; Jie Ma ; Department of Biochemistry and Molecular Biology ; School of Basic Medical Sciences ; Xi'an Jiaotong University Health Science Center ; Xi’an Jiaotong University Health Science Center ; Computational Biology ; Department of Biology ; Friedrich-Alexander Universit?t Erlangen-Nürnberg
- 年：2016
- 作者机构：Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center;Xi’an Jiaotong University Health Science Center;Computational Biology, Department of Biology, Friedrich-Alexander Universit?t Erlangen-Nürnberg;
- 英文论文关键词：Syntaxin-1A ; Oligomerization ; Self-assembly ; Molecular dynamics simulation ; Synaptic vesicle fusion ; Fusion pore
- 会议召开时间：2016-10-20
- 会议录名称：中国生物化学与分子生物学会2016年全国学术会议论文集
- 语种：英文
- 分类号：Q61
- 学会代码：IGSS
- 会议名称：中国生物化学与分子生物学会2016年全国学术会议
- 会议地点：中国浙江杭州
- 主办单位：中国生物化学与分子生物学会
- 学会名称：中国生物化学与分子生物学会
- 页数：2
- 文件大小：6865k
- 原文格式：D
- 会议级别：全国
摘要
<正>Synaptic vesicle fusion in neuronal transmission requires the assembly of soluble N-ethylmaleimide-sensitive factor attachment protein receptor(SNARE)complex formed by a conserved protein family:v-SNARE,synaptobrevin 2,and t-SNAREs,syntaxin-1A and SNAP-25.The syntaxin-1A has been observed to form oligomers of varying size in presynaptic
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