香波配方的体外抗头屑活性检测
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- 英文论文题名：Anti-dandruff Activity Test for Shampoo Formulation
- 论文作者：金沼希 ; Yu-Na Yun ; 朴泰训 ; 李存桓 ; 安水善
- 英文论文作者：So-Hee Kim ; Yu-Na Yun ; Tae-Hum Park ; John-Hwan Lee ; Susun An ; Skin Research Division ; Amorepacific Co.R&D Unit
- 年：2016
- 作者机构：爱茉莉太平洋研究所;
- 论文关键词：抗头屑活性 ; 平板扩散实验 ; 洗发香波 ; 马拉色菌
- 英文论文关键词：anti-dandruff activity ; disk diffusion test ; shampoo ; Malassezia
- 会议召开时间：2016-06-15
- 会议录名称：第十一届中国化妆品学术研讨会论文集
- 英文会议录名称：The Proceedings of the 11th Seminar on Cosmetic China
- 语种：中文
- 分类号：TQ658.33
- 学会代码：ZGXE
- 会议名称：第十一届中国化妆品学术研讨会
- 会议地点：中国上海
- 主办单位：中国香料香精化妆品工业协会
- 学会名称：中国香料香精化妆品工业协会
- 页数：8
- 文件大小：963k
- 原文格式：O
- 会议级别：全国
摘要
头皮屑是一种常见的头皮代谢紊乱现象,困扰着几乎半数的人群。很多化妆品公司开发了含有抗菌物质如巯氧毗啶锌(ZPT)及苯咪丁酮等的抗头屑洗发香波,可以抑制真菌生长,特别是对马拉色菌酵母,一种头屑产生菌的抑制作用十分显著。对于抗头屑洗发香波,检测其是否通过抑制马拉色菌生长来改善头屑状况具有十分重要的意义。本项目旨在建立一种洗发香波抗真菌活性的检测方法。药敏试验的基本方法为最小抑菌浓度(MIC)和平板扩散实验。本实验比较了以硝酸纤维素滤纸和人工皮肤材质(Vitro-skin)作为基质,洗发香波及其它样品在洗去后的抗真菌活性。结果表明,ZPT,苯咪丁酮及其他三种含有ZPT成分的市售洗发香波在洗去之后在硝酸纤维素滤纸和人工皮肤才质(Vitro-skin)上均有部分沉积,据此可观察其抑菌区域。
Dandruff is a common scalp disorder that affects almost half of population.Cosmetic companies have developed anti-dandruff shampoo containing antimicrobial materials such as zinc pyrithione(ZPT) and climbazole which inhibit fungal growth especially Malassezia yeast,dandruff-causing organism.It is essential to examine whether anti-dandruff shampoo reduces Malassezia growth,so that improve dandruff.The aim of this investigation was to establish a test method for antifungal activity of shampoo.The basic methods of antimicrobial susceptibility testing are the minimum inhibitory concentration(MIC) and disk diffusion test.We have compared a disk diffusion test that uses nitrocellulose filter paper and artificial skin substrate(Vitro-Skin)as disks to estimate antifungal activity of shampoo or materials after rinse-off.We have identified that ZPT,climbazole and three commercial shampoos containing ZPT were deposited on disks with nitrocellulose filter paper and artificial skin substrate(Vitro-Skin) even after rinse-off,so zone of inhibition were observed.
Dandruff is a common scalp disorder that affects almost half of population.Cosmetic companies have developed anti-dandruff shampoo containing antimicrobial materials such as zinc pyrithione(ZPT) and climbazole which inhibit fungal growth especially Malassezia yeast,dandruff-causing organism.It is essential to examine whether anti-dandruff shampoo reduces Malassezia growth,so that improve dandruff.The aim of this investigation was to establish a test method for antifungal activity of shampoo.The basic methods of antimicrobial susceptibility testing are the minimum inhibitory concentration(MIC) and disk diffusion test.We have compared a disk diffusion test that uses nitrocellulose filter paper and artificial skin substrate(Vitro-Skin)as disks to estimate antifungal activity of shampoo or materials after rinse-off.We have identified that ZPT,climbazole and three commercial shampoos containing ZPT were deposited on disks with nitrocellulose filter paper and artificial skin substrate(Vitro-Skin) even after rinse-off,so zone of inhibition were observed.
引文
[1]Janniger,C.K.and R.A.Schwartz(1995)."Seborrheic dermatitis."Am Fam Physician 52(1):149-155,159-160.
[2]Hay,R.J.and R.A.Graham-Brown(1997)."Dandruff and seborrhoeic dermatitis:causes and management."Clin Exp Dermatol 22(1):3-6.
[3]Zouboulis,C.C,L.Xia,H.Akamatsu,H.Seltmann,M.Fritsch,S.Hornemann,R.Ruhl,W.Chen,H.Nau and C.E.Orfanos(1998)."The human sebocyte culture model provides new insights into development and management of seborrhoea and acne."Dermatology 196(1):21-31.
[4]Gupta,A.K.,R.Batra,R.Bluhm,T.Boekhout and T.L.Dawson,Jr.(2004)."Skin diseases associated with Malassezia species."J Am Acad Dermatol51(5):785-798.
[5]Faergemann,J.,J.C.Jones,O.Hettler and Y.Loria(1996)."Pityrosporum ovale(Malassezia furfur)as the causative agent of seborrhoeic dermatitis:new treatment options."Br J Dermatol 134 Suppl 46:12-15:discussion 38.
[6]Johnson,B.A.and J.R.Nunley(2000)."Treatment of seborrheic dermatitis."Am Fam Physician 61(9):2703-2710,2713-2704.
[7]#12
[8]Scala,D.(2009).Cleansing bars,Google Patents.
[9]Cao,H.,G.T.Martino and S.A.Vona(2013).Anionic polymer containing(meth)acrylic acid and acrylated esters,Google Patents.
[10]Sinclair,R.D.,J.R.Schwartz,H.L.Rocchetta,T.L.Dawson,Jr.,B.K.Fisher,K.Meinert and E.A.Wilder(2009)."Dandruff and seborrheic dermatitis adversely affect hair quality."Eur J Dermatol 19(4):410-411.
[11]James,A.G.,K.H.Abraham,D.S.Cox,A.E.Moore and J.E.Pople(2013)."Metabolic analysis of the cutaneous fungi Malassezia globosa and M.restricta for insights on scalp condition and dandruff."Int J Cosmet Sci 35(2):169-175.
[12]Peter,R.U.and U.Richarz-Barthauer(1995)."Successful treatment and prophylaxis of scalp seborrhoeic dermatitis and dandruff with 2%ketoconazole shampoo:results of a multicentre,double-blind,placebo-controlled trial."Br J Dermatol 132(3):441-445.
[13]Wigger-Alberti,W,K.Kluge and P.Eisner(2001)."[Clinical effectiveness and tolerance of climbazole containing dandruff shampoo in patients with seborrheic scalp eczema]."Praxis(Bern 1994)90(33):1346-1349
[14]Chen,T.A.and P.B.Hill(2005)."The biology of Malassezia organisms and their ability to induce immune responses and skin disease."Vet Dermatol16(1):4-26.
[15]Reeder,N.L.,J.Kaplan,J.Xu,R.S.Youngquist,J.Wallace,P.Hu,K.D.Juhlin,J.R.Schwartz,R.A.Grant,A.Fieno,S.Nemeth,T.Reichling,J.P.Tiesman,T.Mills,M.Steinke,S.L.Wang and C.W.Saunders(2011)."Zinc pyrithione inhibits yeast growth through copper influx and inactivation of iron-sulfur proteins."Antimicrob Agents Chemother 55(12):5753-5760.
[2]Hay,R.J.and R.A.Graham-Brown(1997)."Dandruff and seborrhoeic dermatitis:causes and management."Clin Exp Dermatol 22(1):3-6.
[3]Zouboulis,C.C,L.Xia,H.Akamatsu,H.Seltmann,M.Fritsch,S.Hornemann,R.Ruhl,W.Chen,H.Nau and C.E.Orfanos(1998)."The human sebocyte culture model provides new insights into development and management of seborrhoea and acne."Dermatology 196(1):21-31.
[4]Gupta,A.K.,R.Batra,R.Bluhm,T.Boekhout and T.L.Dawson,Jr.(2004)."Skin diseases associated with Malassezia species."J Am Acad Dermatol51(5):785-798.
[5]Faergemann,J.,J.C.Jones,O.Hettler and Y.Loria(1996)."Pityrosporum ovale(Malassezia furfur)as the causative agent of seborrhoeic dermatitis:new treatment options."Br J Dermatol 134 Suppl 46:12-15:discussion 38.
[6]Johnson,B.A.and J.R.Nunley(2000)."Treatment of seborrheic dermatitis."Am Fam Physician 61(9):2703-2710,2713-2704.
[7]#12
[8]Scala,D.(2009).Cleansing bars,Google Patents.
[9]Cao,H.,G.T.Martino and S.A.Vona(2013).Anionic polymer containing(meth)acrylic acid and acrylated esters,Google Patents.
[10]Sinclair,R.D.,J.R.Schwartz,H.L.Rocchetta,T.L.Dawson,Jr.,B.K.Fisher,K.Meinert and E.A.Wilder(2009)."Dandruff and seborrheic dermatitis adversely affect hair quality."Eur J Dermatol 19(4):410-411.
[11]James,A.G.,K.H.Abraham,D.S.Cox,A.E.Moore and J.E.Pople(2013)."Metabolic analysis of the cutaneous fungi Malassezia globosa and M.restricta for insights on scalp condition and dandruff."Int J Cosmet Sci 35(2):169-175.
[12]Peter,R.U.and U.Richarz-Barthauer(1995)."Successful treatment and prophylaxis of scalp seborrhoeic dermatitis and dandruff with 2%ketoconazole shampoo:results of a multicentre,double-blind,placebo-controlled trial."Br J Dermatol 132(3):441-445.
[13]Wigger-Alberti,W,K.Kluge and P.Eisner(2001)."[Clinical effectiveness and tolerance of climbazole containing dandruff shampoo in patients with seborrheic scalp eczema]."Praxis(Bern 1994)90(33):1346-1349
[14]Chen,T.A.and P.B.Hill(2005)."The biology of Malassezia organisms and their ability to induce immune responses and skin disease."Vet Dermatol16(1):4-26.
[15]Reeder,N.L.,J.Kaplan,J.Xu,R.S.Youngquist,J.Wallace,P.Hu,K.D.Juhlin,J.R.Schwartz,R.A.Grant,A.Fieno,S.Nemeth,T.Reichling,J.P.Tiesman,T.Mills,M.Steinke,S.L.Wang and C.W.Saunders(2011)."Zinc pyrithione inhibits yeast growth through copper influx and inactivation of iron-sulfur proteins."Antimicrob Agents Chemother 55(12):5753-5760.