7487份血培养致病菌的分离及其临床分布分析
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摘要
目的:分析该院2015年血培养分离菌的分布特点及阳性结果情况。方法:用BacT/Alert3D全自动血培养仪对7487份血液标本进行培养检测,用VITEK2-Compact全自动微生物分析仪对其阳性报警瓶进行鉴定,并对其结果进行回顾性分析。结果:7487份血培养标本共检出病原菌407株,儿童瓶阳性率为2.18%,成人瓶阳性率为12.2%。革兰阴性杆菌289株,占检出病原菌总数的71%,革兰阳性球菌113株,占检出病原菌总数的27.8%,真菌5株,占检出病原茵总数的1.2%。其中最多的致病菌是大肠埃希菌占44.5%,其次是金黄色葡萄球菌占12.8%,肺炎克雷伯菌占9.8%,中间葡萄球菌占3.4%。两瓶或者四瓶培养法的致病菌检出率高于单瓶培养法的检出率。结论:菌血症、败血症和真菌血症临床病死率较高,临床医师应加强血液感染患者血液中病原菌的检测,提高治愈率。
Objective:Analysis of the hospital in 2015 blood culture isolates of the distribution characteristics and positive results.Methods:The blood samples of 7487 blood samples were detected by BacT/Alert 3D automatic blood culture instrument The positive alarm bottle was identified by VITEK2-Compact automatic microbiological analyzer.And the results were retrospectively analyzed.Results:407strains of pathogens were detected in 7487 blood culture samples,The positive rate of children bottle was 2.18%,the positive rate of adult bottle was 12.2%.Gram-negative bacilli 289,accounting for the total number of detected pathogens 71%,Gram-positive cocci 113,accounting for the total number of pathogens detected 27.8%,5 strains of fungi,accounting for 1.2%of the total number of pathogenic bacteria The most common pathogens were Escherichia coli(44.5%),Staphylococcus aureus(12.8%),Klebsiella pneumoniae(9.8%) and Staphylococcus aureus(3.4%).The detection rate of pathogenic bacteria in two bottles or four bottles was higher than that in single bottle culture.Conclusion:Bacteremia,sepsis and mycosis hyperlipidemia clinical mortality,Clinicians should strengthen the blood of patients infected with blood in the detection of pathogens,Improving the cure rate.
引文
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