IL-27 gene therapy prevents the development of autoimmune encephalomyelitis but fails to attenuate established Th17 responses and inflammation in the central nervous system
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- 英文论文题名：IL-27 gene therapy prevents the development of autoimmune encephalomyelitis but fails to attenuate established Th17 responses and inflammation in the central nervous system
- 论文作者：Zhu Jianmin ; Liu Jin-Qing ; Liu Zhihao ; Shi Min ; Zhu Hua ; Bai Xue-Feng
- 英文论文作者：Zhu Jianmin ; Liu Jin-Qing ; Liu Zhihao ; Shi Min ; Zhu Hua ; Bai Xue-Feng ; Pediatric Translational Medicine Institute ; Shanghai Children's Medical Center ; Shanghai Jiaotong University School of Medicine ; Department of Pathology and Comprehensive Cancer Center ; Ohio State University
- 年：2016
- 作者机构：Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine;Department of Pathology and Comprehensive Cancer Center, Ohio State University;
- 英文论文关键词：IL-27 ; autoimmune encephalomyelitis ; Th17
- 会议召开时间：2016-11-04
- 会议录名称：第十一届全国免疫学学术大会分会场交流报告集
- 英文会议录名称：Proceedings of 2016 CSI Congress on Immunology
- 语种：英文
- 分类号：R744.51
- 学会代码：IGMD
- 会议名称：第十一届全国免疫学学术大会
- 会议地点：中国安徽合肥
- 主办单位：中国免疫学会
- 学会名称：中国免疫学会
- 页数：2
- 文件大小：398k
- 原文格式：D
- 会议级别：全国
摘要
<正>Interleukin-27(IL-27)and its subunit P28(also known as IL-30)have been shown to inhibit autoimmunity,and have been suggested as potential immunotherapeutics for autoimmune diseases such as multiple sclerosis(MS).However,the potential of IL-27 and IL-30 as immunotherapeutic,and their mechanisms of action have not been
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