Micro RNA-137 inhibits EFNB2 expression affected by a genetic variant and is expressed aberrantly in peripheral blood of schizophrenia patients

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• 英文论文题名：Micro RNA-137 inhibits EFNB2 expression affected by a genetic variant and is expressed aberrantly in peripheral blood of schizophrenia patients
• 论文作者：Shanshan Wu ; Rui Zhang ; Fayi Nie ; Xiaoli Wang ; Congshan Jiang ; Meng Liu ; Robert K Valenzuela ; Wanqing Liu ; Yongyong Shi ; Jie Ma
• 英文论文作者：Shanshan Wu ; Rui Zhang ; Fayi Nie ; Xiaoli Wang ; Congshan Jiang ; Meng Liu ; Robert K Valenzuela ; Wanqing Liu ; Yongyong Shi ; Jie Ma ; Department of Biochemistry and Molecular Biology ; Xi'an Jiaotong University Health Science Center ; Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University) ; Ministry of Education ; Translational medicine center ; Honghui Hospital ; Xi'an Jiaotong University Health Science Center ; Department of Human Genetics 4 ; Genome Institute of Singapore ; Agency for Science ; Technology and Research (A*STAR) ; Department of Medicinal Chemistry and Molecular Pharmacology ; Purdue University ; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education) ; Bio-X Institutes ; Shanghai Jiao Tong University
• 年：2016
• 作者机构：Department of Biochemistry and Molecular Biology, Xi'an Jiaotong University Health Science Center;Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University),Ministry of Education;Translational medicine center, Honghui Hospital, Xi'an Jiaotong University Health Science Center;Department of Human Genetics 4, Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR);Department of Medicinal Chemistry and Molecular Pharmacology,Purdue University;Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University;
• 英文论文关键词：Schizophrenia ; MiR-137 ; EFNB2 ; SNP ; Regulation
• 会议召开时间：2016-10-20
• 会议录名称：中国生物化学与分子生物学会2016年全国学术会议论文集
• 语种：英文
• 分类号：R749.3
• 学会代码：IGSS
• 会议名称：中国生物化学与分子生物学会2016年全国学术会议
• 会议地点：中国浙江杭州
• 主办单位：中国生物化学与分子生物学会
• 学会名称：中国生物化学与分子生物学会
• 页数：1
• 文件大小：6865k
• 原文格式：D
• 会议级别：全国

摘要

<正>MicroRNAs(mi RNAs)are a class of endogenous and non-coding single-stranded RNAs of approximately 22 nucleotides,many of which are evolutionarily conserved.Genome-wide association studies have identified a robust statistical association between the MIR137 gene and schizophrenia in Europeans,which was replicated in the Han Chinese population in a casecontrol study.In the previous study,we provided evidence for a significant association between the EFNB2 gene and

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