摘要
<正>To investigate the effects of chitosan oligosaccharide(COS)on dendritic cells(DCs)and the role of Toll-like receptor 4(TLR4)in this immune process,Murine spleen CD11c+dendritic cells(SDCs)were isolated and cultured with S-COS and B-COS with polymeration degree of 3-7 and7-16,respectively.The results showed that B-COS up-regulated the expressions of MHCII and CD86 on SDCs,promoted the secretion of TNF-αfrom SDCs.SDCs treated with B-COS
引文
Yibing Dang,Sheng Li,Wenxia Wang,Shujing Wang,Mingming Zou,Yanjie Guo,Jianhui Fan,Yuguang Du,Jianing Zhang(2011)The effects of chitosan oligosaccharide on the activation of murine spleen CD11c+dendritic cells via Toll-like receptor 4.Carbohydrate Polymers83,1075-1081