Seroprevalence of Toxoplasma gondii infection among patients with hand, foot and mouth disease in Henan, China:a hospital-based study
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- 英文论文题名：Seroprevalence of Toxoplasma gondii infection among patients with hand, foot and mouth disease in Henan, China:a hospital-based study
- 论文作者：Shuai Wang ; Chunwei Lan ; Luwen Zhang ; Haizhu Zhang ; Zhijun Yao ; Dong Wang ; Jingbo Ma ; Jiarong Deng ; Shiguo Liu
- 英文论文作者：Shuai Wang ; Chunwei Lan ; Luwen Zhang ; Haizhu Zhang ; Zhijun Yao ; Dong Wang ; Jingbo Ma ; Jiarong Deng ; Shiguo Liu ; Department of Human Parasitology ; School of Basic Medical Sciences ; Xinxiang Medical University ; First People's Hospital of Pingdingshan
- 年：2016
- 作者机构：Department of Human Parasitology, School of Basic Medical Sciences, Xinxiang Medical University;First People's Hospital of Pingdingshan;
- 英文论文关键词：Toxoplasma gondii ; hand ; foot and mouth disease ; seroprevalence ; enzyme-linked immunosorbent assay ; China
- 会议召开时间：2016-08-08
- 会议录名称：中国动物学会寄生虫学专业委员会第十届全国寄生虫学青年工作者学术研讨会论文摘要集
- 英文会议录名称：The Abstracts of the Tenth Symposium for Yong Scientists of China Society of Parasitology
- 语种：英文
- 分类号：R531.8
- 学会代码：JISC
- 会议名称：中国动物学会寄生虫学专业委员会第十届全国寄生虫学青年工作者学术研讨会
- 会议地点：中国四川成都
- 主办单位：中国动物学会寄生虫学专业青年委员会
- 学会名称：中国动物学会寄生虫学专业委员会
- 页数：1
- 文件大小：342k
- 原文格式：D
- 会议级别：全国
摘要
The prevalence of infection with Toxoplasma gondii(T. gondii) in humans has been increasing in China due to the growing number of cats in the country. Hand, foot and mouth disease(HFMD) is a serious public health issue in China and still one of the leading causes of child mortality. However, little is known about the epidemiology of T. gondii infection among HFMD patients. A case-control study of 281 HFMD patients from the First People's Hospital of Pingdingshan in Pingdingshan city, Henan province, central China, and 222 controls from Pingdingshan city was conducted. Anti-T. gondii antibodies were serologically detected using the enzyme-linked immunosorbent assay. We found that the overall anti-T. gondii immunoglobulin G(Ig G) antibody prevalence among HFMD patients was 12.46%, which was significantly higher than that in clinically healthy children(1.80%). The highest T. gondii seroprevalence was detected in critical cases(22.58%), followed by severe cases(11.50%), and the lowest was detected in mild cases(8.33%). The present study is the first survey of T. gondii seroprevalence among HFMD patients in China; 12.46% were defined as seropositive. It is imperative that improved integrated measures are taken to prevent and control T. gondii infection among HFMD patients.
The prevalence of infection with Toxoplasma gondii(T. gondii) in humans has been increasing in China due to the growing number of cats in the country. Hand, foot and mouth disease(HFMD) is a serious public health issue in China and still one of the leading causes of child mortality. However, little is known about the epidemiology of T. gondii infection among HFMD patients. A case-control study of 281 HFMD patients from the First People's Hospital of Pingdingshan in Pingdingshan city, Henan province, central China, and 222 controls from Pingdingshan city was conducted. Anti-T. gondii antibodies were serologically detected using the enzyme-linked immunosorbent assay. We found that the overall anti-T. gondii immunoglobulin G(Ig G) antibody prevalence among HFMD patients was 12.46%, which was significantly higher than that in clinically healthy children(1.80%). The highest T. gondii seroprevalence was detected in critical cases(22.58%), followed by severe cases(11.50%), and the lowest was detected in mild cases(8.33%). The present study is the first survey of T. gondii seroprevalence among HFMD patients in China; 12.46% were defined as seropositive. It is imperative that improved integrated measures are taken to prevent and control T. gondii infection among HFMD patients.
The prevalence of infection with Toxoplasma gondii(T. gondii) in humans has been increasing in China due to the growing number of cats in the country. Hand, foot and mouth disease(HFMD) is a serious public health issue in China and still one of the leading causes of child mortality. However, little is known about the epidemiology of T. gondii infection among HFMD patients. A case-control study of 281 HFMD patients from the First People's Hospital of Pingdingshan in Pingdingshan city, Henan province, central China, and 222 controls from Pingdingshan city was conducted. Anti-T. gondii antibodies were serologically detected using the enzyme-linked immunosorbent assay. We found that the overall anti-T. gondii immunoglobulin G(Ig G) antibody prevalence among HFMD patients was 12.46%, which was significantly higher than that in clinically healthy children(1.80%). The highest T. gondii seroprevalence was detected in critical cases(22.58%), followed by severe cases(11.50%), and the lowest was detected in mild cases(8.33%). The present study is the first survey of T. gondii seroprevalence among HFMD patients in China; 12.46% were defined as seropositive. It is imperative that improved integrated measures are taken to prevent and control T. gondii infection among HFMD patients.
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