髁突在咬合载荷作用下的应力效应
详细信息    本馆镜像全文|  推荐本文 |  |   获取CNKI官网全文
摘要
颞下颌关节(Temporomandibular joint,TMJ)是人体中唯一保持较强终身改建能力的关节,改建活动与其所承受的咬合负荷密切相关,在咀嚼等生理活动中,咬合力传导至TMJ,因此TMJ所承受负荷对其正常的生理功能和一些疾病的形成及转归具有重要的作用。借助现有的先进的研究咬合特征的检测手段和广泛应用于生物力学研究中的有限元分析方法,对咬合与TMJ的生物力学关系进行研究,并且通过改变咬合接触情况来观察TMJ应力分布变化的特点和规律,以探索咬合面形态变化所造成的合力方向及大小的变化,对TMJ载荷的影响,以期对颞下颌关节的改建原因作一初步探索。
     首先,应用T—scanⅡ咬合测定分析系统来分析调合前后TMD患者咬合情况的变化;其次采用CT图像与牙面形态三维扫描相结合的建模方法,建立包括关节盘、下颌骨和上下牙列的三维有限元模型;然后设计了以下三个类型的工况,工况一:对前后牙不同牙位进行垂直加载。由于牙合面形态的引导作用,该垂直载荷将被合面各牙尖斜面分解为多个方向的分力,并通过下颌骨传导至颞下颌关节;工况二:改变下颌第二磨牙的加载位置,分别加载于其合面远中及颊面,由于模型设计为加载方向与咬合接触部位的加载平面相垂直,因此本工况实际上模拟了第一磨牙缺失,第二磨牙近中倾斜的临床咬合紊乱表现,以及锁合表现,其咬合的结果是加载负荷被咬合面结构引导为垂直于接触部位的异常方向的咬合力。工况三:选择第二前磨牙扭转30°,进行咬合接触部位加载,其意义类同于工况二,但模拟的是临床上常见的牙齿扭转错合畸形。通过对上述三种工况下髁状突应力变化的分析,得出以下结果:
     1、通过咬合调改治疗,改变咬合接触特征,使咬合接触分布更加广泛,接触更加密切,其对于颞下颌关节紊乱病具有明确的疗效。
     2、采用本文所描述的实验方法,成功建立了包括上下颌牙列及双侧髁状
    
     第四军医大学硕士学位论文
    突在内的下颌骨三维有限元模型,为今后模拟临床多种咬合载荷探讨额下颌关
    节应力特点创造了条件,并奠定了良好的实验基础。
     3、运用上述三维有限元模型,对调合治疗的机理进行了初步探索。结果
    表明:由于咬合加载的部位、方向和位置不同,在双侧踝状突上可产生不同的
    应力效应,其变化包括应力性质(拉或压应力)变化,应力强度(以压强形式
    表示)变化,以及应力分布特点变化等方面。这种应力特性的变化说明了咬合
    可以通过其外形对垂直载荷的引导效应,改变载荷的方向,影响躲状突的应力
    环境。
     因此,通过本项目的研究得到以下结论:
    1、颤下颌关节生物力学环境与咬合力密切相关,而咬合面形态特点对咬合力
     的传导具有重要的引导作用,这种引导作用对颜下颌关节内的应力环境也
     可产生重要的影响。
    2、牙列中咬合加载的前后部位不同,对双侧额下颌关节也会产生不同的应力
     效果。
    3、改善或重建咬合面形态,是口腔医学临床上进行许多治疗的重要内容,通
     过合理治疗合面形态,将对改善额下领关节的应力环境,促进其正常改建,
     具有重要的意义。
Temporomandibular joint (TMJ) is the only joint that keeps relatively active reconstruction ability for all one's life. The load on TMJ is very important for its physiological function and the development of some diseases. Occlusal force is the most direct origin of that load. So investigation on the occlusion's characteristic must be done by using modern occlusal measures and FEM.Then changing contact areas,we can find out the sreess's abnormal distribution.
    ?T-scan II system is used to analysis occlusal conditions before and after occlusal adjustment. ?Constitute FEM model containing mandibulan disc and all teeth by CT and three-dimensions scan. ?According to tooth's different position in the arc,FEM models are applied with upright load; load position changing; rotate second premolar, in this three conditions we investigate the stress distribution of the condyle.
    The results indicated as the following.
    1. T梥can n system is suitable for determine the occlusion's accurate positons. In the case of TMD patients, after occlusal adjustment bilateral occlusion get much more balanced.
    2.A FEM model containing mandibulan disc and all teethis is formed .When the model loaded with different patterns of stress by altering teeth location, TMJ stress transformation can be infered and relationship between occlusion and TMJ maybe revealed.
    3.Adapt or reconstruct the shape of teeth contact area is very important in oral clinic therapy. By adjusting occlusal shape appropriately,the TMJ stress will
    -3-
    
    
    
    
    occur corresponding changes,and this will be helpful to TMJ physiological function transformation.
引文
[1]王惠芸主编 合学 第一版 北京 人民卫生出版社 1990:127
    [2]王美青等 咬合对双侧颞下颌关节形态对称性影响的解剖学研究 全国第二届颞下颌关节紊乱综合征专题研讨会论文汇编.北京,1997
    [3]Barghi N., Aguilar T., Martines C. Prevaence of types of temporomandibular joint clickings in subjects with missing posterior teeth. J Prosthet Dent. 1987,57:617-620
    [4]Martinez M. Prevaence of TMJ clickings in subjects with missing posterior teeth. J Dent Res. 1984,63:345
    [5]王美青 ICO和ICP异常与颅颌功能紊乱关系系列研究 第四军医大学博士学位论文
    [6]王美青,颜朝云,李刚 四种异常合因素与颞下颌关节弹响关系的病例对照研究 中华流行病学杂志 1994,15特刊(1):433
    [7]Wang Y. The role of condyle position and occlusion in temporomandibular joint dysfunction syndrome. Chinese Med J, 1987,100(8):621-627
    [8]Pullinger AG., Seligman DA., Solberg WK. Temporomandibular disorders. Part Ⅱ: Occlusal factors associated with temporomandibular joint tenderness and dysfunction. J Prothet Dent. 1988,59:363
    [9]陈永进,王惠芸 深覆合与颅颌功能紊乱 实用口腔医学杂志 1992,8(4):251
    [10]Gianelly AA. Longitudinal evaluation of condylar position in extraction and nonextraction treatment. AM J Orthod Dentofac Orthop. 1991,100:416
    [11]Hellsing E. Increased overbite and craniomandibular disorders. A clinical approach. Am J Dentofac Orthop. 1990,98:516
    [12]王美青,颜朝云,刘豆豆等 第三磨牙异常与颅颌功能紊乱关系的研究 中华口腔医学杂志 1994,29(4):85
    [13]Asazuma Y, Isogai Y, Watanabe K, et al. Changes in gnathosonic and tooth contact characteristics induced by experimental occlusal interferences created using a full-cast double crown J Oral Rehabil. 1995,22(3): 203
    [14]Randow K., Carlsson K., Edlund J. et al. The effect of an occlusal interference on the mesecatory system. An experimental investigation. Odont Revy. 1976,27:215
    [15]Rugh JD., Barghi N., Drago CJ. Experimental occlusal discrepancies and nocturnal
    
    bruxism. J Prothet Dent. 1984,51:548
    [16] Okeson JP. Orfacial pain, Chicago: Quintessence Inc, 1996,46-47:244
    [17] Christensen LV, Rassouli NM. Experimental occlusal interference. Part Ⅱ. Masseteric EMGresponses to an intercuspal interference. J Oral Rehabil. 1995, 22(7):521
    [18] Rassouli NM, Christensen LV. Experimental occlusal interference. Part Ⅲ. Mandibular rotations induced by a rigid interference. J Oral Rehabil. 1995, 22(10): 781
    [19] Christensen LV, Rassouli NM, Experimental occlusal interference. Part Ⅳ. Mandibular rotations induced by a pliable interference. J Oral Rehabil. 1995, 22(11): 835
    [20] Mongini F. Anatomic and clinical evaluation of the relationship between the temporomandibular joint and occlusion. J Prothet Dent. 1977,38(5):539
    [21] 徐樱华 (牙合)与颞颌关节骨性结构形态间的关系 中华口腔科杂志 1979,14(3):142
    [22] Solberg WK., Bibb CA., Nordstrom BB. et al. Malocclusion associate with temporomandibular joint changes in young adults at autopsy. Am J Orthod. 1986,89(4):326
    [23] 滕胜毅,徐樱华,陈孟诗等 颞下颌关节盘的表面结构、力学性能和关节润滑关系的动物实验研究 华西口腔医学杂志 1994,12(2):97
    [24] 傅开元;马绪臣;张震康 创伤致家兔颞下颌关节滑膜和软骨超微结构的改变 中华口腔医学杂志 1998,33(1):18-20
    [25] 傅开元;马绪臣;张震康 创伤对家兔颞下颌关节影响的扫描电镜观察 中华口腔医学杂志 1995,30(5):277-279
    [26] 傅开元;马绪臣;张震康 创伤对家兔颞下颌关节的影响:X线及病理观察 口腔颌面外科杂志 1996,6(2):108-111
    [27] 王海鹰,周继林,洪民 咬合创伤时颞颌关节软组织P物质样免疫反应的影响 口腔颌面外科杂志 1997,7(1):15-19
    [28] Kvinnsland S; Kvinnsland I; Kristiansen AB. Effect of experimental traumatic occlusion on blood flow in the temporomandibular joint of the rat. Acta-Odontol-Scand. 1993,51(5):293-8
    [29] Ricketts RM. Variations of the temporomandibular joint as revealed by cephalometric laminagraph. Am J Orthod. 1950,36:877
    [30] Mongini F. Condyle remodeling after occlusal therapy. J Prosthet Dent. 1980,43(5):568
    [31] McNamara JA Jr., Carlson DS. Quantitative analysis of temporomandibular joint adaptations to protrusive function. Am J Orthod 1979,76(6):593
    [32] 胡荣党 温州医学院学报 1996,26(4):210
    
    
    [33] 胡敏,周继林,洪民 一侧后牙缺失对髁状突和关节盘酶组织化学的影响 口腔医学纵横 1995,11(2):102
    [34] 胡敏,周继林,洪民 小型猪单侧牙缺失对颞下颌关节影响的组织学研究 中华口腔医学杂志 1996,31(3):153
    [35] 张庆国 白求恩医科大学学报 1997,23(4):396
    [36] 段小红 髁状突骨上组织改建的实验研究 第四军医大学硕士学位论文 1997,31
    [37] 胡凯,周继林,刘洪臣等 拾夹板对关节重建术后患者下颌骨应力分布的影响 军医进修学院学报 1999,20(3):204
    [38] Hellman M. Variations in occlusion. Dent Cosmos, 1921, 63:608.
    [39] YurkstasA, ManlyRS. Measurment of Occlusal contact area effective inmastication. Am J Orthod 1949;35:185.
    [40] GianniriAI. Occlusal Contacts in maximum intercuspation and craniomandibular dysfunctionin 16-to-17-years old adolescents. JOralRebabil 1991;18:49.
    [41] BeryonH. OcclusalrelafionsandmasticationinAustralianaborigins. JProsthetDent 1964;22:597.
    [42] McNamaraDC, HenryPJ. Terminal hinge contact in denti-tions. JProsthetDent 1974;32:405.
    [43] RiiseC. A clinical study of the number of occlusal tooth contacts in the intercuspalposition at light and hard pres-sureinadults. JOralRehabil 1982;9:469.
    [44] ZiebertGJ, DoneganSJ. Toothcontactsandstabilitybeforeandafterocclusaladjustmetnt. JProsth etDent 1979;42:276.
    [45] Athanasionetal. Occlusionaltoothcontactsinnaturalnor-maladultdentitionincentricocclusion studiedbyphotoc-clusiontechnique. ScandJDentRes 1989;97:439.
    [46] 刘平,傅民魁.青少年正常合的合接触点研究.口腔正畸学 1998;4:156.
    [47] 刘平,傅民魁.颞下颌关节紊乱综合征的合接触点研究.口腔正畸学 1999;6(3):103
    [48] 陈一怀,王惠芸,马轩祥等,.不同合力牙尖交错位咬合接触的计算机图像分析,实用口腔医学杂志,2000,16(4):268
    [49] 陈一怀,王惠芸,马轩祥等,正常合牙尖交错位咬合接触的计算机图像分析,实用口腔医学杂志,2000,16(5):398
    [50] Maness, M.L., and Podoloff, R., Distribution of occlusal contacts in maximum intercuspation. J Prosthet Dent 1989;62:238-42.
    [51] Mizui M, Nabeshima F, Tosa J, et al. Quntitative analysis of occlusal balance in intercuspal position using the T-Scan system. Int J Prosthodont 1994;7(1):62-71.
    
    
    [52] Cartagena A G, Sequeros O G, Garcia V C G. Analysis of Two Methods for Occlusal Contacts Registration with the T-Scan System, Journal of Oral Rehabilitation 1996, 24(6):426-432.
    [53] Garcia, V.C.G., Cartagena, A.C., Sequeros, O.G. Evaluation of Occlusal Contacts In Maximum Intercuspation Using the T-Scan System, Journal of Oral Rehabilitation 1997,24(12): 899-903.
    [54] Kerstein, R.B., and Wright, N. An electromyographic and computer analysis of patients suffering with chronic myofascial pain dysfunction syndrome; pre and post treatment with immediate complete anterior guidance development. JPD 1991;66(5):677-686.
    [55] Kerstein, R.B. Computerized Occlusal Analysis In Implant Prosthondontics, Implant News & Views, 2000;2(1):1
    [56] Iwase, M., Sugimori, M., Kurachi, Y., Nagumo, M.: Changes in Bite Force and Occlusal Contacts in Patients Treated for Mandibular Prognathism sy Orthognathic Surgery. Journal of Oral Maxillofax Surg, 1998;56:850
    [57] 王海涛,罗秋凤,周必方,等.压电薄膜力传感器及其牙咬力的测量应用研究[J].仪器仪表学报,2001,(3)增刊:51-52.
    [58] 王海涛,罗秋凤,周必方,等.光纤微位移传感器及其牙齿咀嚼运动的测量研究[J].仪器仪表学报,2001,(4)增刊:23-24.
    [59] 王海涛,罗秋凤,周必方,等.人体牙齿咀嚼状况的实时测量方法.传感器技术,2001;20(10):41
    [60] 钱宗才,齐春,杨庆华.咬合接触点测量的计算机图像分析系统的建立.实用口腔医学杂志,1995,11:120
    [61] 王美青,胡敏,陈金武,姚秀芳,颜朝云,柴田考典.单侧部分后牙反合者的咀嚼运动轨迹研究 实用口腔医学杂志.2000;16(3):184
    [62] 王美青,王惠芸.颅颌功能紊乱者咀嚼运动轨迹的研究.华西口腔医学杂志,1993,11:245
    [63] 康宏,易新竹.颞下颌关节的生物力学.生物医学工程学杂志,2000;17(3):324
    [64] MonginiF. Thestomatologicalsystem. Chicago, QuintessencePublishingCo, Inc 1984; pp: 11
    [65] ChenJ, XuLiangfeng. Afiniteelementanalysisofthehumantemporomandibularjoint. JBiomech Eng, 1994;116: 401
    [66] CherryCQ, FrewAJr, Highcondylec-tomyfortreatmentofarthritisofthetem-poromandibularjo int. JOralSurg, 1977;35:285
    [67] KamelchukLS, MajorPW. Degenerativedis-easeofthetemporomandibularjoint. JOrofa-cialPa
    
    in, 1995;9:168
    [68] MankinHJ. Theresponseofarticularcartilagetomechanicalinjury. JBoneJointSurg(Am), 1982;64:460
    [69] MonginiF. Influenceoffunctionontem-poromandibularjointremodelinganddegeder-ativedise ase. DentClinNorthAm, 1983;27:479
    [70] IsraelHA, SaedNejadF, RatcliffeA. Earlydi-agnosisofosteoarthrosisofthetemporo-mandibula rjoint: Correlationbetweenarthro-scopicdiagnosisandkeratinsulfatelevelinsynovialfluid. JOral MaxillofacSurg, 1991; 49:708
    [71] 洪民,周继林,黄继贤,等.关节外调整术治疗颞下颌关节结构紊乱与肌功能失调.中华口腔医学杂志,1991;26:109
    [72] 张震康,傅民魁主编.颞下颌关节病,第一版.人民卫生出版社.1987:48;53
    [73] ForemanP. Temooromandibularjointandmy-ofascialpaindysfunction- Somecurrentcon-cepts: Ⅰ. diagnosis. NZDentJ, 1985;81:47
    [74] DolwickMF, KatzbergRW, HelmsCA, etal. Anthrotomographicevalutionofthetemporo-mandi bularjoint. JOralSurg, 1979;37:793
    [75] BronsteinSL, TomasettiBJ, RyanDE. In-ternalderangementsofthetemporo-mandibularjoint: Correlationofarthrogra-phywithsurgicalfindings. JOralSurg, 1981;39:572
    [76] ItoT, GibbsCH, MargullesBonnetR, etal. Loadingonthetemporomandibularjointswithfiveoccl usalconditions. JProsthetDent, 1986;56:478
    [77] 周继林,洪民,刘洪臣,等.合夹板在颞下颌关节紊乱综合征术后的早期治疗.中华口腔医学杂志,1991;26:303
    [78] Agarwal S, Long P, Gassner R, Piesco NP, Buckley MJ. Cyclic tensile strain suppresses catabolic effects of interleukin-1 beta in fibrochondrocytes from the temporomandibular joint. Arthritis-Rheum. 2001; 44(3): 608
    [79] WrightM, JobanputraP, BavingtonCetal. Effectofintermittentpressure-inducedstrainontheele ctrophysiologyofculturedhumanchondrocytes: evidenceforthepresenceofstretch-activatedme mbraneionchannels. ClinScience, 1996;90(1): 61
    [80] HolmvallK, CamperL, JobanssonSetal. Chondrocyteandchondrosarcomacellintegrinswithaff inityforcellintegrinswithaffinityforcollagentypeandtheirresponsetomechanicalstress.ExpCell Res, 1995;221: 496
    [81] 蒋孝煜主编.有限元法基础.第2版.北京:清华大学出版社,1992.
    [82] 张少锋.有限元法及其在口腔医学研究中的应用[J].国外医学口腔医学分
    
    册,1990,17(2):92~94.
    [83] Farah JW., Craig RG. Finite element stress analysis of a restored axisymmetric first molar.. J Dent Res 1974,53(4):859
    [84] Tanne K, Tanaka E, Sakuda M. Stress distribution in the temporomandibular joint producdic by orthopedic chincup forces applied in varying directions: A three-dimensional analytic approach with the finite element method. Am J Orthod Dentofac Orthop, 1996,110(6):502
    [85] Richard AR., Pao YC., Robert FK. Periodontal ligament stresses in the initiation of occlusal traumatism. J Periodont Res. 1984,19:238
    [86] 魏洪涛,张天夫,曾晨光,刘英,刘景新 牙颌三维有限元模型生成方法的探讨 白求恩医科大学学报 2000,02:150
    [87] 周学军,赵志河,赵美英等 下颌骨三有限元模型的边界约束设计 华西口腔医学杂志 1999,17(1):29
    [88] Hart RT., Hennebel VV., Thongpreda N. et al. Modeling, the biomechanics of the mandible; a three-dimensional finite element study. J Biomech 1992,25:261
    [89] Korioth TW., Hannam AG. Deformation of the human mandible during simulated tooth clenching. J Dent Res. 1994,73(1):56
    [90] 周学军,赵志河,赵美英等 包括下颌骨的颞下颌关节三维有限元模型的建立 实用口腔医学杂志 2000,16(1):17
    [91] 杨辉 刘洪臣 荣起国 颞下颌关节三维有限元模型的建立 中华口腔医学杂志 1999,34(5):320
    [92] 胡凯,周继林,刘洪臣等 正常人下颌骨的三维有限元应力分析 军医进修学院学报 1998,19(2):97
    [93] 胡凯,周继林,洪民等 建立模拟功能状态下的下颌骨三维有限元模型 口腔颌面外科杂志 1997,7(3):183
    [94] 张旻,王美青等 颞下颌关节与咬合关系研究三维有限元模型的建立 口腔颌面修复学杂志 2000,4:197
    [95] Korioth TW., Hannam AG. Deformation of the human mandible during simulated tooth clenching. J Dent Res. 1994,73(1):56
    [96] 周书敏,何明元,张延宏 用三维有限单元法对健康牙周膜在11种载荷下应力分布的研究 中华口腔医学杂志 1989,24(6):334
    [97] 李俊,魏文州,段春.应用CT技术建立磨牙三维有限元模型.湖北医科大学学报
    
    1999;20(4):342
    [98] 徐娟,刘洪臣等.下颌前磨牙创伤咬合点加载的三维有限元分析.口腔颌面修复学杂志 2001;2(1):8
    [99] 洪瑾,夏文薇,朱亚琴,王晓仪,熊焕国.有限元法建立下颌第一磨牙模型及受力分析.上海口腔医学 2001;10(4):342
    [100] 郑元俐 张富强 陈笠 王成焘 采用牙CT技术建立完整下颌骨三维有限元模型 实用口腔医学杂志 2000;16(2):134
    [101] Stanford CM, Brand RA. Towarding an understanding of implant occlusion and strain adaptive bone modeling and remodeling. J Prosthet Dent 1999, 81:553-61.
    [102] Weinberg LA, Kruger BA. Comparison of implant/prostheses loading with four clinical variables. Int J Prosthodont 1995, 8:421-33.
    [103] Kaukinen JA, EdgeMJ, Lang BR. The influence of occlusal design on simulated masticatory forces transferred to implant-retained prostheses and supporting bone. J Prosthet Dent 1996, 76:50-55.
    [104] Johnson RB. Effect of altered occlusal function on transseptal ligment and new bone thickness in the periodontium of the rat. Anat Res 1990,187:91.
    [105] Kvinnsland S, et al. Effect of experimental traumatic occlusion on periodontal and pulpal blood flow. Acta Odontal Scand 1992, 50:211-9.
    [106] 元方,王美青等.渐进性咬合紊乱导致猴颞下颌关节骨关节病的实验研究初探 实用口腔医学杂志 2000,16:27-30.
    [107] 王美青等.颞颌关节紊乱症病因的实验研究 口腔医学 1994,14(4):190
    [108] Osborn JW., Baragar FA. Predicted and observed shapes of human mandibular condyles. J Biomech. 1992,25:967
    [109] Faulkner MG., Hatcher DS., Hay A. A three-dimensional investigation of the temporomandibular joint loading. J Biomech 1987,20:997
    [110] dos Santos J Jr., Blackman RB., Nelson SJ. Vectorial analysis of the static equilibrium of forces generated in the mandible in centric occlusion, geoup function, and balanced occlusion relationships. J Prosthet Dent. 1991,65:557
    [111] Koolstra JH., van Eijden TMGJ., Weijs WA. et al. A three-dimensional mathematical model of the human masticatory system predicting maximum possible bie forces. J Biomech. 1988,21(7):563
    [112] Dorrit W. Intraarticular pressure in the functioning human temporomandibular joint
    
    and its alterative by uniform elevation of the occlusal plane. J Oral Maxillofac Surg. 1994,52(7):671
    [113] Hatcher DC., Fualkner MG., Hay A. Development of mechnical and mathematic models to study temporomandibular joint loading. J Prothet Dent. 1986,55:377
    [114] 周书敏,朱希涛,高鹏飞等 牙周支持组织三维光弹性应力分析 中华口腔医学杂志 1987,22(6):313
    [115] 胡凯 颞下颌关节形态结构的力学因素 国外医学生物医学工程分册 1999,22(4)233
    [116] 王美青等.咬合与髁状突形态对称性间的相关关系解剖学研究 实用口腔医学杂志 2001,17:147-50
    [117] McNeill C. Management of temporomandibular disorders: concepts and controversies. J Prosthet Dent, 1997,77(5):510-22
    [118] McNeill C. History and evolution of TMD concepts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 1997,83(1):51-60
    [119] Mers, G. and Anderson, J.R: Nature of contact in 32 adults. J Dent Res, 1971,50(1):7,
    [120] Melzark R. The McGill Pain Questionnaire: major properties and scoring methods. Pain. 1975,1(4):357
    [121] Ziebert GJ, Donegan SJ. Tooth contacts and stability before and after occlusal adjustment. J Prothet Dent 1979; 42(2);276.
    [122] 王美青,王惠云.颞颌关节紊乱综合征合病因的临床试验研究[J].口腔医学,1994,14(4):190-192.
    [123] 刘晓东,王美青.渐进性咬和紊乱对幼年兔颞下颌关节的影响.实用口腔医学杂志,2002,18(4):329
    [124] 陈金武,王美青,姚秀芳等.合紊乱对猴髁突软骨中TGF—β1分布的影响.实用口腔医学杂志 2001,17(2):159
    [125] Lee WC, Eakle WS. Stress induced cervical lesions: review of advances in the past 10 years. J Prosthet Dent 1996,75(5):487-93.
    [126] Hass R, Mensdorff-Pouilly N, Mailath G. Survival of 1992 IMZ implants followed for up to 100 months. Int J Oral Implants 1996, 11:581-8.
    [127] Johnson RB. Effect of altered occlusal function on transseptal ligment and new bone thickness in the periodontium of the rat. Anat Res 1990,187:91.
    [128] Turner CH, Forwood MR, Rho JY, et al. Mechanical loading thresholds for lamellar
    
    and woven bone formation. J Bone Miner Res 1994,9:87.
    [129] 张旻,王美青等.垂直载荷下正常合及安氏二类错合根尖应力分布规律的光弹研究 实用口腔医学杂志 2000,10(3):26

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700