1.中医药配合西医治疗原发性肝癌进展(文献综述)2.杨新中教授治疗肝癌临床经验总结
详细信息    本馆镜像全文|  推荐本文 |  |   获取CNKI官网全文
摘要
近年来随着肿瘤的综合治疗概念的确立,中医药积极参与肝癌临床防治,肝癌总体疗效得到了进一步的提高。
     中药生脉注射液配合介入栓塞化疗可延长生存期、提高免疫指标。清开灵注射液,配合介入栓塞可减少发热,提高肝功损害的耐受性。参麦注射液明显改善肝癌介入者全身功能,减轻胃肠道反应,提高机体免疫功能。
     运用中医辨证论治治疗栓塞化疗后综合症疗效显著。徐伯平以清热柔肝中药防治肝癌栓塞化疗术后的毒副反应,发现清热柔肝法对TACE后的发热和疼痛,具有良好的防治作用。曹喜才等运用中药在解决腹水方面有独到之处等。王怀璋总结临床研究,发现中医药在减轻介入栓塞化疗的副作用,提高患者生存质量,增强机体抗病能力方面均有一定效果。陈连起以益气养阴,化瘀止痛,清热解毒法治疗肝癌介入后胁痛疗效较好。
     以中药华蟾素和羟基喜树碱,莪术油及其提取物β-榄香烯作为灌注药物具有高效低毒的优点。
     肝癌切除术前和术后服用托里消毒散均可提高患者的细胞免疫功能,术后服用还可明显改善患者的肝功能。
     消癌胶囊具有益气活血,祛瘀止痛、破结之功效,因而可改善微循环血液的高凝状态,增强CD3AK细胞的抗癌作用。
     肝癌的治疗采取了中西医结合的综合治疗方法,西医更多注意的是局部治疗,而中医更加重视的是整体调理,二者结合,取长补短,相得益彰,提高肝癌的临床治疗效果。未来的研究将面对早期发展,更有效的治疗和控制复发和转移等课题,从基础研究水平上取得进一步的发展。
The Traditional Chinese Medicine (TCM) and the herbals have taken part in the clinical therapy of hepatocarcinoma with the building of the complicated therapy conception in the recent years. And the whole therapic effect becomes better.
    Shengmai injection and SIL-2 can improve effective rate, survival rate and immunologic function in treating liver cancer after chemotherapy combined with amboliztion. And Qingkailing Injection (QI) can alleviate symptoms such as fever, abdominal for post-transcatheter arterial chemoembolization(post-TACE) syndrome, and also can enhance the endurance of the liver function. Shenmai Injection can improve the function of the whole body obviously, alleviate advice reaction, especially for the gastric reaction, and enhance the immune.
    The effect of Chinese herbals in prevention and reduction of TACE syndrone by BZLZ (Bianzheng Lunzhi) is notable. The "Qingre Rougan" recipe used by Xuboping is effective for prevention and treatment of the syndrome after the liver cancer TACE, especially in pain and fever. Caocaixi got a good effect in resolving ascites by Chinese herbals after BZLZ. Wanghuaizhang found Chinese herbals could improve the quality of live of the liver cancer patients. Chenlianqi use TCM theory to explain the pains of the liver cancer, so he put "Yiqi yangyin ,huoxuehuayu" as the main recipe to alleviate the pain.
    Chinese herbals, such as Huachansu, CAO and its ramification can used for TACE, and the merit is better effect and lower toxic reaction then the chemical medicine. So the Chinese herbals have the chance to be used to TACE in clinical therapy.
    Tuoli Xiaodu Powder (TLXDP) can enhance the cell mediated immune in liver carcinoma patients before and after surgical operation, and also can improve the liver functions after operation.
    CD3AK cells combined with Traditional Chinese Medicine -xiaoaijiaonang in treating hepatocel luar cancer (HCC) is an effective means. The percentage of Tcell subsets CDS, CD4, CDS increased, and the sIL-2R levels decreased in the patients after treatment by CD3AK and Xiaoaijiaonang.
    The therapic method of live cancer is complicated. While TCM combines with western medicine emphasize both local and whole therapy, so it can get better effective. And the whole process of the illness of liver neoplasms relies on the function of the liver, so protecting the function the liver is signification. In the future, the study will emphasize on the early development, more effective therapy and controlling recrudesce and metastasis of the cancer. So we must study the liver cancer from the basic lever.
引文
1.高中度,茅爱武等,TAE术后白介素2联合生脉注射液治疗肝癌临床观察,中国肿瘤临床与康复,2000年,第7卷第2期:58-60。
    2.陈喆,凌昌全等,生脉注射液对肝癌TAE术增效减毒作用,安徽中医学院学报,2000年,第19卷第5期:13-15。
    3.王安浦,李捷,大剂量清开灵注射液在肝动脉栓塞术中的应用
    4.罗海英,吴万垠等,清开灵注射液治疗原发性肝癌介入后综合征,广州中医药大学学报,2001年6月第18卷第2期:130-133
    5.杨廷旭,郭进华等,化疗配合参麦注射液治疗原发性肝癌38例中国中西医结合杂志,2000年10月第20卷第10期:787-788
    6.徐伯平,黄国贤等,清热柔肝法防治肝癌栓塞化疗后综合征的研究,《癌症》,2000年第19卷第8期,804-806
    7.曹喜才等,肝癌介入治疗后期综合措施的探讨,临床放射学杂志,2001年第20卷第9期:704-706
    8.王怀璋,肝癌栓塞化疗后免疫及中药治疗的临床观察,中国中西医结合杂志,1998年第7期:411-413
    9.陈连起,介入治疗加剧胁痛的中医疗法,中国中医基础医学杂志,1998年8月第4卷增刊(上):109-110
    10.刘庄,复方华蟾素口服液抗乙型肝炎病毒体外实验研究.中国中西医结合杂志,1996年12期:739
    11.林钧华,宋明志等,华蟾素和羟基喜树碱肝动脉灌注栓塞治疗原发性肝癌的疗效观察,上海中医药杂志,97年11期:18-19
    12.吴万垠,罗云坚等,莪术油肝动脉灌注治疗大鼠移植性肝癌,华人消化杂志,1998,6(10):859-861
    13.杨杰,王胜文等,榄香烯介入治疗中晚期肝癌69例临床分析,白求恩医科大学学报,2001年,第27卷第4期:400[13]
    14.黎洪浩,梁俊雄等,托里消毒散对手术前后肝癌患者细胞免疫功能的影响,中国中西医结合杂志,2001年,第21卷第10期:739-741
    15.梁俊雄,邝幸华等,托里消毒散对原发性肝癌栓塞化疗不良反应的对抗作用,北京中医药大学学报,2000年,第23卷第5期:56-57
    16.莫钦国,梁安民等,CD3AK细胞结合中药治疗原发性肝癌的疗效初步观察,广西医学,1999年-第6期:1074-1076
    17.杨新中,李金彩等,对中医肿瘤病因病机与治疗的思考,中国医药学报,1999年第6期:57-609
    18.杨新中,熊裕家等,中西医结合治疗肿瘤的疗效标准初探,中医杂志,2000年,第8期:497-499
    19.杨新中,常见恶性肿瘤的中西医治疗,北京医科大学联合出版社,206-217
    20.孟志强,于尔辛等,健脾理气中药对肝癌端粒酶活性的影响,中国中医基础医学杂志 2000年第6卷第1期:23-26

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700