子宫锭治疗慢性宫颈炎宫颈糜烂（湿热下注证）临床疗效观察
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摘要
目的:探讨子宫锭治疗慢性宫颈炎宫颈糜烂(湿热下注证)的临床疗效。方法:采用随机、对照原则,将符合宫颈糜烂(湿热下注证)诊断标准和中医辨证的80例患者纳入研究,治疗组和对照组各40例,分别予子宫锭和宫颈炎康栓阴道纳药。在治疗3个疗程后,观察宫颈糜烂面积、炎症程度及中医症状的改善,进行疗效评价。两组在人口学特征与病程、病情分布差异无显著性,具有可比性。结果:1.研究结果显示两组综合疗效比较无显著性差异(P>0.05),治疗组总有效率95.00%,对照组总有效率92.50%。2.两组宫颈糜烂面疗效比较无显著性差异(P>0.05),治疗组痊愈12例,总有效率87.50%,对照组痊愈8例,总有效率88.75%。中医症候疗效比较无显著异(P>0.05),治疗组痊愈8例,总有效率100%,对照组痊愈10例,总有效率100%。3.子宫锭治疗组经相关性分析结果表明,糜烂面积与疗效有相关性,面积越小,疗效越好。4.各组治疗前后宫颈糜烂面积、炎症程度、阴道清洁度、中医症候积分比较有显著差异(p<0.05),说明两组药均能有效改善宫颈糜烂(湿热下注证)的临床症状,缩小糜烂面,减轻炎症程度及阴道清洁度。治疗后组间比较无显著性差异(P>0.05)。5.不良反应:试验期间,两组均未出现明显不良反应。结论:子宫锭能有效治疗中医辨证为湿热下注的宫颈糜烂,明显改善宫颈局部病变、糜烂面积、炎症程度、阴道清洁度及相关临床症状,无毒副作用,安全可靠,值得推广应用。
Objective: To investigate the clinical evaluation of Zi Gong Ding treating chronic cervicitis and cervical erosion(damp invasion of lower energizer). Methods: Adopt stochastic contrast method.80 patients, accorded with the diagnostic standard of cervieal erosion of westem medicine and the type of damp invasion of lower energizer according to differentiation of syndromes in TCM, were divided into treatment and control group at random: 40 cases of the treatment group treated with the Zi Gong Ding via vagina; 40 cases of the control group given Gong Jing Yan Kang Shuan via Vagina. After the treatment of three courses, do the clinical evaluation by observing the size of cervieal erosion surface,the degree of inflammation,TCM Syndrome penthemeron,colp-clearing grade before and after the treatment and scoring records and following up. Two groups of study population characteristics and course of disease, disease distribution of the difference was not significant, comparable.Results: 1. There was no significant difference between these two groups on the comprehensive(P>0.05).The total effective rate of the treatment group,was95.00% ,while the control group was92.50%.2. There was no significant difference (P> 0.05) in two sets of surface effects of cervical erosion:treatment group, 12 cases fully recovered, the total rate of 87.50%; control group, 8 cases of recovery, the total effective rate 88.75%. Efficacy of traditional Chinese medicine symptoms showes no significant differences (P> 0.05), eight cases recovered in the treatment group with a total effective rate 100% while in the control group healed 10 cases also with a total effective rate 100%.3. The correlation analysis results of Zi Gong Ding treatment group show that the erosion area has relevance to therapeutic effects with an area smaller, the better curative effect.4. Both could significantly depress the integral about the size of cervieal erosion surface,the degree of inflammation,colp- clearing grade and the TCM syndrome penthemeron after the treatment(P<0.05).It stated that the two groups had significant effect on the symptoms.There was no significant difference between the two groups after treatment(P>0.05).5. Adverse reactions and side effects: no obvious adverse reactions and side effects in both groups during clinical study.Conclusion : Zi Gong Ding suppository could effectivly treat chronic cervicitis and cervical erosion(damp invasion of lower energizer),obviously improve erosion area, inflammation, vaginal cleanliness and the correlate symptoms, had no side effects. Therefore, Zi Gong Ding suppository is a kind of safe, reliable medicine and worthy of popularization.
Objective: To investigate the clinical evaluation of Zi Gong Ding treating chronic cervicitis and cervical erosion(damp invasion of lower energizer). Methods: Adopt stochastic contrast method.80 patients, accorded with the diagnostic standard of cervieal erosion of westem medicine and the type of damp invasion of lower energizer according to differentiation of syndromes in TCM, were divided into treatment and control group at random: 40 cases of the treatment group treated with the Zi Gong Ding via vagina; 40 cases of the control group given Gong Jing Yan Kang Shuan via Vagina. After the treatment of three courses, do the clinical evaluation by observing the size of cervieal erosion surface,the degree of inflammation,TCM Syndrome penthemeron,colp-clearing grade before and after the treatment and scoring records and following up. Two groups of study population characteristics and course of disease, disease distribution of the difference was not significant, comparable.Results: 1. There was no significant difference between these two groups on the comprehensive(P>0.05).The total effective rate of the treatment group,was95.00% ,while the control group was92.50%.2. There was no significant difference (P> 0.05) in two sets of surface effects of cervical erosion:treatment group, 12 cases fully recovered, the total rate of 87.50%; control group, 8 cases of recovery, the total effective rate 88.75%. Efficacy of traditional Chinese medicine symptoms showes no significant differences (P> 0.05), eight cases recovered in the treatment group with a total effective rate 100% while in the control group healed 10 cases also with a total effective rate 100%.3. The correlation analysis results of Zi Gong Ding treatment group show that the erosion area has relevance to therapeutic effects with an area smaller, the better curative effect.4. Both could significantly depress the integral about the size of cervieal erosion surface,the degree of inflammation,colp- clearing grade and the TCM syndrome penthemeron after the treatment(P<0.05).It stated that the two groups had significant effect on the symptoms.There was no significant difference between the two groups after treatment(P>0.05).5. Adverse reactions and side effects: no obvious adverse reactions and side effects in both groups during clinical study.Conclusion : Zi Gong Ding suppository could effectivly treat chronic cervicitis and cervical erosion(damp invasion of lower energizer),obviously improve erosion area, inflammation, vaginal cleanliness and the correlate symptoms, had no side effects. Therefore, Zi Gong Ding suppository is a kind of safe, reliable medicine and worthy of popularization.
引文
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