何天有学术经验总结暨疏肝兴阳法治疗慢性非菌性前列腺炎致性功能障碍临床研究
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摘要
研究目的：采用随机、对照的研究方法,观察疏肝兴阳法治疗慢性非菌性前列腺炎致性功能障碍的临床疗效,通过国际认可的慢性前列腺炎症状和性功能评价方法评价疏肝兴阳法治疗慢性非菌性前列腺炎致性功能障碍的优效性,为临床治疗慢性非菌性前列腺炎和性功能障碍提供科学客观的临床研究依据。
研究方法：将62例慢性非菌性前列腺炎致性功能障碍病例随机分为“疏肝兴阳法”治疗组和药物舍尼通对照组。分别采用疏肝兴阳法针药结合治疗和舍尼通口服治疗,治疗组每日针刺1次,留针30分钟,每隔10分钟采用捻转法行针1次。每周治疗6次,连续治疗4周。中药疏肝兴阳方汤剂早晚温服,每日1剂,连续治疗4周。舍尼通片口服每次1片,一日2次,连续治疗4周。采用美国国立卫生研究院慢性前列腺炎症状指数评分表(NIH-CPSI)记录治疗前后排尿症状评分、疼痛症状评分、生活质量评分,中国早泄患者性功能评分表(CISFPE)对患者进行性功能评价,国际勃起功能指数-5评分表(IIEF-5)评价患者勃起功能。
研究结果：
(1)NIH-CPSI:治疗组治疗后14天和28天后NIH-CPSI评分均显著低于治疗前NIH-CPSI评分(P<0.05)；对照组治疗14天和28天后NIH-CPSI评分均显著低于治疗前NIH-CPSI评分(P<0.05)。组间比较显示治疗14天和28天后两个时间点治疗组NIH-CPSI评分均显著低于对照组同一时间点NIH-CPSI评分(p<0.05)。
(2)CISFPE:治疗组治疗后14天和28天后CISFPE评分均显著高于治疗前CISFPE评分(P<0.05)；对照组治疗14天和28天后CISFPE评分均显著高于治疗前CISFPE评分(P<0.05)。组问比较显示治疗14天和28天后两个时间点治疗组CISFPE评分均显著高于对照组同一时间点CISFPE评分(P<0.05)。
(3)IIEF-5:治疗组治疗后14天和28天后IIEF-5评分均显著高于治疗前IIEF-5评分(P<0.05)；对照组治疗14天和28天后IIEF-5评分均显著高于治疗前IIEF-5评分(P<0.05)。组间比较显示治疗14天和28天后两个时间点治疗组IIEF-5评分均显著高于对照组同一时间点IIEF-5评分(P<0.05),对照组治疗14天与治疗28天进行组内比较无显著性差异(P>0.05)。结果提示“疏肝兴阳法”与舍尼通均可以改善慢性非菌性前列腺炎患者勃起功能,对照组28天与14天比较,无显著性差异。
结论：
(1)疏肝兴阳法治疗慢性非菌性前列腺炎临床疗效优于舍尼通药物治疗组；
(2)疏肝兴阳法治疗慢性非菌性前列腺炎致性功能障碍临床疗效明显优于尼通药物治疗组；
(3)疏肝兴阳法治疗慢性非菌性前列腺炎致性功能障碍临床起效较舍尼通药物治疗组快而且持久。
Objective: To evaluate the "Shuganxingyang" method on its clinical efficacy and superiority for Chronic non-bacterial prostatitis and sexual-dysfunction.
Method:62patients of Chronic non-bacterial prostatitis and sexual-dysfunction were randomly divided into two groups, the study group which were given the "Shuganxingyang" treatment (30cases) and the control group which were given Cernilton herb treatment (32cases). The study group was given one acupuncture treatment every day, with30minutes of needle retention. They were treated for4weeks.The control group ws given Cernilton herb treatment Tid, They were treated for4weeks. On the14th,28th day statistical notes of the clinical efficacy was taken. We used the CPSI(Chronic Prostatitis Symptom Index), CISFPE(Chinese Index of Sex Function of Premature Ejaculation), IIEF-5(International Index of Erectile Function5) to evaluate the clinical effection.
Results:
1. CPSI:After14and28days the CPSI in the study group was clearly lower than before treatment (P 2. CISFPE:After14,28days of treatment CISFPE of both groups was clearly higher than before treatment (P<0.05). After14and28days of treatment there were significant differences in the CISFPE between the two groups (P<0.05)
3. IIEF-5:After14and28days of treatment the IIEF-5for both groups were clearly higher than the IIEF-5before the treatment (P<0.05), There were significant difference in the IIEF-5between14and28days treatment in treatment group (P<0.05). While there were no significant difference in the IIEF-5between14and28days treatment in control group (P>0.05)
Conclusions:
(1) The "Shuganxingyang" method has a certain clinical efficacy for Chronic non-bacterial prostatitis has significant difference in clinical efficacy from Cernilton herb treatment.
(2) The "Shuganxingyang" method has the advantage on forward efficacy when used for sexual-dysfunction.
(3) The "Shuganxingyang" method has works faster than Cernilton herb treatment when it comes to treat Chronic non-bacterial prostatitis and sexual-dysfunction.
研究方法：将62例慢性非菌性前列腺炎致性功能障碍病例随机分为“疏肝兴阳法”治疗组和药物舍尼通对照组。分别采用疏肝兴阳法针药结合治疗和舍尼通口服治疗,治疗组每日针刺1次,留针30分钟,每隔10分钟采用捻转法行针1次。每周治疗6次,连续治疗4周。中药疏肝兴阳方汤剂早晚温服,每日1剂,连续治疗4周。舍尼通片口服每次1片,一日2次,连续治疗4周。采用美国国立卫生研究院慢性前列腺炎症状指数评分表(NIH-CPSI)记录治疗前后排尿症状评分、疼痛症状评分、生活质量评分,中国早泄患者性功能评分表(CISFPE)对患者进行性功能评价,国际勃起功能指数-5评分表(IIEF-5)评价患者勃起功能。
研究结果：
(1)NIH-CPSI:治疗组治疗后14天和28天后NIH-CPSI评分均显著低于治疗前NIH-CPSI评分(P<0.05)；对照组治疗14天和28天后NIH-CPSI评分均显著低于治疗前NIH-CPSI评分(P<0.05)。组间比较显示治疗14天和28天后两个时间点治疗组NIH-CPSI评分均显著低于对照组同一时间点NIH-CPSI评分(p<0.05)。
(2)CISFPE:治疗组治疗后14天和28天后CISFPE评分均显著高于治疗前CISFPE评分(P<0.05)；对照组治疗14天和28天后CISFPE评分均显著高于治疗前CISFPE评分(P<0.05)。组问比较显示治疗14天和28天后两个时间点治疗组CISFPE评分均显著高于对照组同一时间点CISFPE评分(P<0.05)。
(3)IIEF-5:治疗组治疗后14天和28天后IIEF-5评分均显著高于治疗前IIEF-5评分(P<0.05)；对照组治疗14天和28天后IIEF-5评分均显著高于治疗前IIEF-5评分(P<0.05)。组间比较显示治疗14天和28天后两个时间点治疗组IIEF-5评分均显著高于对照组同一时间点IIEF-5评分(P<0.05),对照组治疗14天与治疗28天进行组内比较无显著性差异(P>0.05)。结果提示“疏肝兴阳法”与舍尼通均可以改善慢性非菌性前列腺炎患者勃起功能,对照组28天与14天比较,无显著性差异。
结论：
(1)疏肝兴阳法治疗慢性非菌性前列腺炎临床疗效优于舍尼通药物治疗组；
(2)疏肝兴阳法治疗慢性非菌性前列腺炎致性功能障碍临床疗效明显优于尼通药物治疗组；
(3)疏肝兴阳法治疗慢性非菌性前列腺炎致性功能障碍临床起效较舍尼通药物治疗组快而且持久。
Objective: To evaluate the "Shuganxingyang" method on its clinical efficacy and superiority for Chronic non-bacterial prostatitis and sexual-dysfunction.
Method:62patients of Chronic non-bacterial prostatitis and sexual-dysfunction were randomly divided into two groups, the study group which were given the "Shuganxingyang" treatment (30cases) and the control group which were given Cernilton herb treatment (32cases). The study group was given one acupuncture treatment every day, with30minutes of needle retention. They were treated for4weeks.The control group ws given Cernilton herb treatment Tid, They were treated for4weeks. On the14th,28th day statistical notes of the clinical efficacy was taken. We used the CPSI(Chronic Prostatitis Symptom Index), CISFPE(Chinese Index of Sex Function of Premature Ejaculation), IIEF-5(International Index of Erectile Function5) to evaluate the clinical effection.
Results:
1. CPSI:After14and28days the CPSI in the study group was clearly lower than before treatment (P
3. IIEF-5:After14and28days of treatment the IIEF-5for both groups were clearly higher than the IIEF-5before the treatment (P<0.05), There were significant difference in the IIEF-5between14and28days treatment in treatment group (P<0.05). While there were no significant difference in the IIEF-5between14and28days treatment in control group (P>0.05)
Conclusions:
(1) The "Shuganxingyang" method has a certain clinical efficacy for Chronic non-bacterial prostatitis has significant difference in clinical efficacy from Cernilton herb treatment.
(2) The "Shuganxingyang" method has the advantage on forward efficacy when used for sexual-dysfunction.
(3) The "Shuganxingyang" method has works faster than Cernilton herb treatment when it comes to treat Chronic non-bacterial prostatitis and sexual-dysfunction.
引文
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