氨基酸过渡金属配合物的红外与拉曼光谱研究
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摘要
氨基酸是构成生物体内蛋白质、酶等的基本结构单元,金属氨基酸配合物参与人体内的各种代谢及生理生化过程,在生命过程中扮演着极其重要的角色。研究氨基酸金属配合物的配位机理,对于深入了解金属离子的生物效应及复杂生物体的生命活动具有重要意义。
本论文主要以L-甘氨酸、L-丙氨酸、L-苏氨酸与锌的配合物为研究对象,测定了配合物的红外和拉曼光谱,讨论了氨基酸金属配合物的结构和配位机理。用电导法讨论了反应时间、反应温度对氨基酸锌配位体系的影响,确定了等电点条件下三种氨基酸锌配合物的配位比均为2∶1(氨基酸∶金属)。探讨了pH值、共存阴离子对氨基酸锌配位体系的影响,总结了氨基酸锌配合物的配位规律和反应机理。此外,还对此三种氨基酸与金属铜(Ⅱ)、铁(Ⅲ)的配合物进行了研究。研究结果表明:
(1)在等电点条件下,氨基酸以羧基氧原子与Zn~(2+)进行配位反应,其中L-甘氨酸、L-丙氨酸分子中的羧基氧原子以单齿配位方式与Zn~(2+)配位,而L-苏氨酸分子中的羧基氧原子以双齿配位方式参与配位,形成正四面体的氨基酸锌配合物。
(2)氨基酸及锌离子在不同的pH值下以不同的离子状态存在。当pH1.0时,氨基酸分子中的-NH_3~+、-COOH基团均不含孤对电子,不能与Zn~(2+)进行配位。当pH 13.0的碱性条件下,氨基酸以R-CH_2-CH(NH_2)-COO~-状态存在,此时分子中的-NH_2、-COO~-基团均能向Zn~(2+)提供孤对电子,从而形成五元螯合环配合物。
(3)反应体系中有不同阴离子(SO_4~(2-)、NO_3~-)共存时,SO_4~(2-)、NO_3~-均可作为单齿配体参与氨基酸与锌的配位反应,形成混配配合物。
(4)在等电点条件下,氨基酸以羧基氧原子与金属铜(Ⅱ)、铁(Ⅲ)进行配位。其中氨基酸铜(Ⅱ)配合物中三种氨基酸的羧基均以单齿形式参与配位,构成dsp~2的杂化,形成四配位的平面正方形氨基酸铜(Ⅱ)配合物;甘氨酸铁(Ⅲ)、丙氨酸铁(Ⅲ)配合物中的羧基以单齿形式,苏氨酸铁(Ⅲ)配合物中的羧基以双齿形式参与配位,采取sp~3杂化,形成四配位的正四面体的氨基酸铁(Ⅲ)配合物。
(5)三种氨基酸金属配合物中,氨基酸铜(Ⅱ)配合物的稳定性最大,其M-O键最牢固,M-O伸缩振动峰频率低。
The amino acid is a basic structural unit composing the protein and enzyme in living body.The metal complex with amino acid is participating in various metabolism and physiology biochemistry process in human body,so it plays an important role in life process.Therefore,the study on coordination mechanism of metal complex with amino acid plays an important role of the biological effect of metal ions and the life activity of complicated biological system.
The complex of L-glycine,L-alanine,L-threonine with zinc were studied in this paper.The Infrared and Raman spectrum of complexes were determined,the structure and coordination mechanism of metal complexes with amino acids were discussed.By the determination of amino acid zinc complexes' conductance,the influencing factors of reaction time and reaction temperature have been discussed,and the coordination ratio at isoelectric point has been confirmed as 2:1(amino acid:metal ion).Following these conclusions,the influence such as different pH value and co-existed negative ions to amino acid zinc system was discussed.Then the coordination law and reaction mechanism of amino acid zinc complex were generalized.Besides,the copper(Ⅱ) amino acid complex,the iron(Ⅲ)amino acid complex have been studied in the paper.The results can be concluded as follow:
(1)The amino acid coordinated with Zn~(2+)by -COO~- at isoelectric point.The L-glycine and L-alanine coordinated with Zn~(2+)by the oxygen atom of carboxyl in monodentate mode,however,the theronine coordinated in bidentate mode.The amino acid zinc complex has the configuration of regular tetrahedron.
(2)The amino acid and zinc ion have different states with different pH value.When the pH value is 1.0,the amino acid can not coordinate with Zn~(2+),because both -NH_3~+ and -COOH group are not containing lone pair electrons.When amino acid exists in R-CH_2-CH(NH_2)-COO~- at pH 13.0,the -NH_2 and -COO~- can provide lone pair electrons which can coordinate with Zn~(2+)to form chelating ring complex.
(3)When the amino acid coexisted with different negative ion (SO_4~(2-)、NO_3~-),Both SO_4~(2-)and NO_3~- can react with Zn~(2+)as monodentate ligand,and formed the mixed ligand complexes.
(4)The amino acid coordinated with copper(Ⅱ)and iron(Ⅲ)by -COO~- at isoelectric point.And the oxygen atom of carboxyl was monodentate mode in amino acid copper complex.The complex was four-coordinated in a square planar configuration with the hybridization of dsp~2.And the oxygen atom of carboxyl was monodentate mode in glycine-iron and alanine-iron complex,it was bidentate mode in theronine-iron complex.The complex was four-coordinated in a regular tetrahedron configuration with the hybridization of sp~3.
(5)The results showed that the stabilization of amino acid copper (Ⅱ)complex is better than the other two complexes.In copper complex the bond M-O is the strongest,and the stretching vibration frequency of M-O is low.
本论文主要以L-甘氨酸、L-丙氨酸、L-苏氨酸与锌的配合物为研究对象,测定了配合物的红外和拉曼光谱,讨论了氨基酸金属配合物的结构和配位机理。用电导法讨论了反应时间、反应温度对氨基酸锌配位体系的影响,确定了等电点条件下三种氨基酸锌配合物的配位比均为2∶1(氨基酸∶金属)。探讨了pH值、共存阴离子对氨基酸锌配位体系的影响,总结了氨基酸锌配合物的配位规律和反应机理。此外,还对此三种氨基酸与金属铜(Ⅱ)、铁(Ⅲ)的配合物进行了研究。研究结果表明:
(1)在等电点条件下,氨基酸以羧基氧原子与Zn~(2+)进行配位反应,其中L-甘氨酸、L-丙氨酸分子中的羧基氧原子以单齿配位方式与Zn~(2+)配位,而L-苏氨酸分子中的羧基氧原子以双齿配位方式参与配位,形成正四面体的氨基酸锌配合物。
(2)氨基酸及锌离子在不同的pH值下以不同的离子状态存在。当pH1.0时,氨基酸分子中的-NH_3~+、-COOH基团均不含孤对电子,不能与Zn~(2+)进行配位。当pH 13.0的碱性条件下,氨基酸以R-CH_2-CH(NH_2)-COO~-状态存在,此时分子中的-NH_2、-COO~-基团均能向Zn~(2+)提供孤对电子,从而形成五元螯合环配合物。
(3)反应体系中有不同阴离子(SO_4~(2-)、NO_3~-)共存时,SO_4~(2-)、NO_3~-均可作为单齿配体参与氨基酸与锌的配位反应,形成混配配合物。
(4)在等电点条件下,氨基酸以羧基氧原子与金属铜(Ⅱ)、铁(Ⅲ)进行配位。其中氨基酸铜(Ⅱ)配合物中三种氨基酸的羧基均以单齿形式参与配位,构成dsp~2的杂化,形成四配位的平面正方形氨基酸铜(Ⅱ)配合物;甘氨酸铁(Ⅲ)、丙氨酸铁(Ⅲ)配合物中的羧基以单齿形式,苏氨酸铁(Ⅲ)配合物中的羧基以双齿形式参与配位,采取sp~3杂化,形成四配位的正四面体的氨基酸铁(Ⅲ)配合物。
(5)三种氨基酸金属配合物中,氨基酸铜(Ⅱ)配合物的稳定性最大,其M-O键最牢固,M-O伸缩振动峰频率低。
The amino acid is a basic structural unit composing the protein and enzyme in living body.The metal complex with amino acid is participating in various metabolism and physiology biochemistry process in human body,so it plays an important role in life process.Therefore,the study on coordination mechanism of metal complex with amino acid plays an important role of the biological effect of metal ions and the life activity of complicated biological system.
The complex of L-glycine,L-alanine,L-threonine with zinc were studied in this paper.The Infrared and Raman spectrum of complexes were determined,the structure and coordination mechanism of metal complexes with amino acids were discussed.By the determination of amino acid zinc complexes' conductance,the influencing factors of reaction time and reaction temperature have been discussed,and the coordination ratio at isoelectric point has been confirmed as 2:1(amino acid:metal ion).Following these conclusions,the influence such as different pH value and co-existed negative ions to amino acid zinc system was discussed.Then the coordination law and reaction mechanism of amino acid zinc complex were generalized.Besides,the copper(Ⅱ) amino acid complex,the iron(Ⅲ)amino acid complex have been studied in the paper.The results can be concluded as follow:
(1)The amino acid coordinated with Zn~(2+)by -COO~- at isoelectric point.The L-glycine and L-alanine coordinated with Zn~(2+)by the oxygen atom of carboxyl in monodentate mode,however,the theronine coordinated in bidentate mode.The amino acid zinc complex has the configuration of regular tetrahedron.
(2)The amino acid and zinc ion have different states with different pH value.When the pH value is 1.0,the amino acid can not coordinate with Zn~(2+),because both -NH_3~+ and -COOH group are not containing lone pair electrons.When amino acid exists in R-CH_2-CH(NH_2)-COO~- at pH 13.0,the -NH_2 and -COO~- can provide lone pair electrons which can coordinate with Zn~(2+)to form chelating ring complex.
(3)When the amino acid coexisted with different negative ion (SO_4~(2-)、NO_3~-),Both SO_4~(2-)and NO_3~- can react with Zn~(2+)as monodentate ligand,and formed the mixed ligand complexes.
(4)The amino acid coordinated with copper(Ⅱ)and iron(Ⅲ)by -COO~- at isoelectric point.And the oxygen atom of carboxyl was monodentate mode in amino acid copper complex.The complex was four-coordinated in a square planar configuration with the hybridization of dsp~2.And the oxygen atom of carboxyl was monodentate mode in glycine-iron and alanine-iron complex,it was bidentate mode in theronine-iron complex.The complex was four-coordinated in a regular tetrahedron configuration with the hybridization of sp~3.
(5)The results showed that the stabilization of amino acid copper (Ⅱ)complex is better than the other two complexes.In copper complex the bond M-O is the strongest,and the stretching vibration frequency of M-O is low.
引文
[1]蒋滢.氨基酸的应用[M].北京:世界图书出版公司,1996:1
[2]刘树祥,刘春丽,田来进.锌(Ⅱ)-氨基酸水杨醛席夫碱-α-氨基酸三元配合物的稳定性[J].无机化学学报,1999,15(1):114-117
[3]高恩君,刘瑕,刘祁涛.钯(Ⅱ)-芳香氮碱一氨基酸三元配合物中的电子效应和 芳环堆积作用[J].无机化学学报,2002,18(2):442-446
[4]王则民,杨海峰,王桂华等.稀土脯氨酸邻菲哕啉固体配合物合成和表征[J].无机化学学报,1999,15(6):721-726
[5]计亮年,黄锦汪,莫庭焕.生物无机化学导论第二版[M].广州.中山大学出版社,2001.208
[6]邵建华,韩永圣,高芝祥.复合氨基酸稀土元素螯合物的生产和应用研究进展[J].稀土,2001,22(5):59-62
[7]J.Legendziewicz,E.Huskowska.Application of luminescence and absorption spectroscopy and x-ray methods to studies of Ln~(+3)ions interaction with aminoacids[J].Inorganica Chimica Acta,1984,95(2):57-63
[8]许良忠,文丽荣.过渡金属-甘氨酸配合物的IR光谱[J],光谱实验室,2002,19(5):641-643
[9]丁邦东,顾仁敖.稀土金属有机配合物的红外和拉曼光谱研究[J],中国稀土学报,2001,19(6):552-554
[10]张朝平,张炜.某些蛋白质同银(Ⅰ)-铜(Ⅱ)离子配合物的IR、Raman和UV/VIS 光谱研究[J],化学试剂,1999,21(1):11-14
[11]S.Jarmelo,P.R.Carey,R.Fausto.The Raman Spectra of sreine and 3,3-dideutero-serine in aqueous solution[J],Vibrational Spectroscopy,2007,43:104-110
[12]高胜利,侯育冬,冀棉等.锌盐与α-氨基酸配合物的XPS的研究[J],光谱学与光谱分析,2001,21(1):81-83
[13]蒋才武,陈超球,陈灵.微波辐射下苯氧乙酸锌、甘氨酸锌的固相合成及表征[J],广西科学,1999,6(3):193-196
[14]潘家来编著,激光拉曼光谱在有机化学上的应用[M],北京:化学工业出版社,1986
[15]柯以侃,董慧茹.分析化学手册第三分册:光谱分析[M],北京:化学工业出版社,1998
[16]游效曾.配位化合物的结构和性质[M],北京:科学出版社,1992:233
[17]王阳,吴晓斌,王佳等.近场拉曼光谱在纳米结构表征中的应用[J].光谱学与光谱分析,2006,26(7):1253-1259
[18]黄海平,田英芬,何尚锦等.拉曼光谱在高分子中的应用新进展[J].热固性树脂,2001,16(2):38-44
[19]张树霖.简介生物学领域中的拉曼散射研究[J].光散射学报,1995,7(1):47-51
[20]余国滔.拉曼光谱在医学上的应用(Ⅰ)[J].光散射学报,1996,8(2):113-122
[21]李灿,李美俊.拉曼光谱在催化研究中应用的进展[J].分子催化,2003,17(3):213-240
[22]杨春艳.红外光谱在腐蚀研究中的应用与发展[J].腐蚀与防腐,2001,22(10):434-440
[23]黄卫宁,张君慧,R.C.Hoseney.FT-Raman光谱与谷物化学研究的最新进展[J].食品科学,2004,25(11):411-415
[24]庞新安.近红外光谱技术及其在农产品品质分析中的应用[J].广西农业生物科学,2007,26(1):83-87
[25]王吉有,王闵,刘玲.拉曼光谱在考古中的应用[J].光散射学报,2006,18(2):130-133
[26]王昶.波谱分析技术在宝石鉴定中的应用评述[J].光谱实验室,2001,18(3):301-303
[27]张鹏翔,赵金涛,杨延勇.显微拉曼技术在公安法学中的应用[J].光散射学报,1998,1(10):3-4
[28]陈丹丹,张涛,任丽萍.金属及其配合物与生物分子相互作用机理的研究进展[J].分析科学学报,2006,22(5):600-604
[29]陈燕青,戴立益,杨宝林等.稀土组氨酸配合物的合成和性质研究[J].化学世界,1996,8(3):353-358
[30]陈芳,胡珍珠,石鹤等.稀土与L-亮氨酸、咪唑三元配合物的合成及抑菌作用研究[J].稀有金属,2006,29(3):311-314
[31]Sumiyuki Akihama,Shigeshi Togoshima.Chemotherapeutic drags against viruses ⅩⅩⅪⅤ.Aativiral effect of zinc complexes encephalitis.Chem.Pharm.Bull,1962,(10):1254
[32]张瑞华.赖氨酸锌的合成[J].饲料工业,2004,25(5):35-37
[33]朱妙琴.甘氨酸合铜(Ⅱ)配合物的固、液相反应合成与表征[J].光谱实验室,2006,23(1):110-114
[34]蒋才武,陈超球,梁利芳等.微波辐射条件下Cu(Ⅱ)、Co(Ⅱ)、Ni(Ⅱ)、Zn(Ⅱ)与甘氨酸配合物的固相合成、表征及应用[J].广西师范学报(自然科学版),2000,17(1):32-37
[35]柴之芳,祝汉民.微量元素化学概论[M].北京:原子能出版社,1994
[36]刘建睿,侯育冬,高胜利等.锌盐与L-α-组氨酸配合物行为的相化学研究[J].化学学报,1999,57:485-490
[37]屈景年,刘义,曾荣英等.L-胱氨酸合锌(Ⅱ)钠的热化学[J].化学研究与应用,2004,16(3):386-87
[38]屈景年,刘义,涂麟俊等.L-丙氨酸和L-组氨酸与铜离子混配合物的热化学[J].化学通报,2002,(11):786-790
[39]高胜利,冀棉,刘建睿等.稀土硝酸盐与组氨酸配合物的研究[J].中国科学(B 辑),1999,29(3):264-272
[40]俞志刚,李锦州,刘双全等.二苯基呋喃甲酰基吡唑啉酮及其金属配合物的合成与电化学行为[J].应用化学,2004,21(12):1300-1304
[41]童叶翔,康北笙,杨绮琴.金属配位化合物溶液的电化学研究[J].电化学,1999,5(4):361-370
[42]Watters J I,Dewitt R,J.Am.Chem.Soc.1960,82:1333
[43]何美,周华峰,谢颖等.铜-二肽(氨基酸)二元配合物的稳定性研究[J],沈阳化工学院学报,2003,17(1):7-11
[44]许鹏奎.铜[Cu(Ⅱ)]-氨基酸配合物稳定常数的测定[J],甘肃教育学院学报(自然科学版),1999,13(2):49-51
[45]刘文涵,单胜艳,张丹等.硫化锌法原子吸收间接测定半胱氨酸络合物稳定常数[J],光谱学与光谱分析,2005,25(11):1872-1874
[46]卢小泉,康敬万,高锦章编著.配合物电分析化学[M].北京:中国石化出版社,2000:120
[47]刘伟明,刘巨涛,冷红霞等.L-赖氨酸锌配合物结构的理论研究[J],分子科学学报,2001,17(4):247-250
[48]刘文涵,王丽丽,李祖光等.数值拟合研究原子吸收间接测定谷氨酸的机理[J],浙江工业大学学报,2004,32(6):615-619
[49]刘宗怀,张孟民,宋迪生等.稀土硝酸盐甘氨酸固体配合物的合成及杀菌活性 试验[J],稀土,1995,16(3):5-8
[50]杨频.生物无机化学导论[M].西安:西安交通大学出版社,1991:299
[51]王则民,杨海峰,王桂华等.稀土脯氨酸邻菲啰啉固体配合物合成和表征[J].无机化学学报,1999,15(6):721-726
[52]范镇基.氨基酸络合物应用新进展[J].广东科技,1997,2:10-11
[53]王瑞瑶,金天柱,郑智平.镧系元素配位化学新领域[J].化学学报,2000,58(12):1481-1492
[54]邵建华,韩永圣,高芝祥.复合氨基酸稀土元素螯合物的生产和应用研究进展[J].稀土,2001,22(5):59-62
[55]Miguel Machuqueiro,Tamis Darbre.Zinc mediated methyl transfer from trimethyl phosphate to chelating and non-chelating alkyl tiiols.Model for Zn-dependent methytransferases[J].Inorganin Biochemistry,2003,94:193-196
[56]Gunilla U.M.Lindstrom,Erik Johansson,Martin Nygren.Quality assurance of multivariate analytical measurements by principal components analysis[J].Chemosphere,1985,14:1695-1701
[57]王文韵,曾广赋.我国分子光谱的发展史[J].光谱学与光谱分析,1983,3(1):5-14
[58]乔冬平.浅谈傅立叶变换红外光谱技术的进展及其应用[J].材料开发与应用,1999,14(1):44-46
[59]刘敏娜,王桂清,卢其斌.红外光谱技术的进展及其应用[J].精细化工中间体,2001,31(6):9-12
[60]梁齐治.红外光谱在真伪鉴别上的应用[J].北京联合大学学报,2000,14(2):69-74
[61]何晓东,汤河源,徐新.FT-IR显微红外光谱图像系统及其应用[J].现代仪器使用与维修,1999(2):32-34
[62]EKGASITS,ISHIDAH.New optical depth-profiling technique by use of the multiple-frequency approach with single ATR FT-IR spectrum:theoretical development[J].Applied Spectroscopy,1997,51(10):1488-1495
[63]李淑玲.拉曼光谱仪及其应用进展[J].岩矿测试,1998,17(4):312-316
[64]M.Fleischmann,P.J.Hendra,A.J.McQuillan.Raman Spectra of pyridine adsorbed at a silver electrode[J].Chemical Physics Letters,1974,26(2):163-166
[65]刘玲.激光拉曼光谱及其应用进展[J].山西大学学报(自然科学版),2001,24(3):279-282
[66]于世林,李寅蔚主编.波谱分析法[M].重庆:重庆大学出版社,1994,91-94
[67]中本一雄.无机和配位化合物的红外和拉曼光谱[M].北京:化学工业出版社,1991,8-32
[68]Nodal I.Generalized Tow-dimensional Correlation Method Applicable to Infrared Raman and other Types of Spectroscopy[J].Appl Spectrosc,1993,47:1239
[69]Aust Jeffrey F,Booksh Karl S,Stellman Christopher M.Precise Determination of Percent of Epoxide Polymers and Composites via Fiber-Optie Raman Spectroscopy and Multivariate Analysis[J].Appl Spectrosc,1997,51(3):247-250
[70]Stellman Christopher M,Aust Jeffrey F,Myrik Michael L.In Situ Spectroscopy Study of Microwave Polymerization[J].Appl Spectrosc,1995,49(3):392-394.
[71]褚明福,邹乐西,仲敬荣.拉曼和红外光谱在核材料研究中的应用[J].稀有金属,2005,29(1):106-111
[72]Sun J S,Michaelian K H.Surface-Enhanced Raman Scattering of Acrylamide and Polyacrylamide Adsorbed on Silver Colloid Surface:Polymerization of acrylamide on silver[J].J.RamanSpectroscopy,1987,18(6):409-414
[73]Heine T.M.,Ahern A.M.,Garrell R.L.Surface-enhanced Raman spectroscopy of peptides:preferential N-terminal adsorption on colloidal silver[J].J.Am.Chem.Soc.,1991,113(3):846-854
[74]Sang Kyu Kim,Myung Soo Kim,Se Won Suh.Surface-Enhanced Raman Scattering of Aromatic Amino Acid and Their Glycyl Dipeptides in Silver Sol[J].J.Raman Spectroscopy,1987,18(3):171-175
[75]孙素琴,郁鉴源,胡鑫尧.分子光谱法无损鉴别生药材的最新进展[J].光谱学与光谱分析,1999,19(6):841-843
[76]孙素琴,周群,郁鉴源.分子振动光谱法与中药研究的最新进展[J].光谱学与光谱分析,2000,20(2):199-202
[77]李如璧.激光拉曼光谱技术在宝石鉴定中的应用[J].常州技术师范学院学报,2001,7(2):1-5
[78]祖恩东,段云彪,张鹏翔.显微共焦拉曼光谱在宝石鉴定中的应用[J].云南大学学报,2004,26(1):51-55
[79]王怡林,杨群,张鹏翔等.元代铜镜腐蚀情形的拉曼光谱研究[J].光谱学与光谱分析,2002,22(1):48-50
[80]杨群,王怡林,张鹏翔等.武定恐龙化石的显微拉曼光谱研究[J].光谱学与光谱分析,2002,22(5):793-795
[81]钱晓凡,施英,张鹏翔等.枪击残留物拉曼光谱研究[J].光散射学报,2001,13(1):45-48
[82]刘国志,赵金涛,徐存英等.麻黄素和左旋咪唑显微拉曼测试分析[J].光谱学与光谱分析,2002,22(2):248-250
[83]赵金涛,徐存英,段云彪等.痕迹走私海洛因显微拉曼测试分析[J].光谱学与光谱分析,2002,22(4):588-590
[84]药林桃,刘木华,刘道金等.激光技术在农产品质量检测中的研究进展[J].激光生物学报,2007,16(3):369-373
[85]Wachs I E.Characterization of Catalytic Materials[M].Boston:Butterworth-Heinemann,1992
[86]Krylov O V,Mamedov A Kh,Mirzabekova S R.New Development in Selective Oxidation[M].Amsterdam:Elsevier,1994
[87]薛奇.红外傅里叶变换反射吸收光谱的原理及金属表面涂层结构的表征[J].化学通报,1989,(12):33-35
[1]杨频,高飞.生物无机化学原理[M].北京:科学出版社,2002
[2]计亮年,黄锦汪,莫庭焕等.生物无机化学导论第二版[M].广州:中山大学出版社,2001
[3]蒋滢主编.氨基酸的应用[M].北京:世界图书出版公司,1996:5-7
[4]Sumiyuki Akihama,Shigeshi Togoshima.Chemotherapeutic drags against viruses ⅩⅩⅪⅤ.Aativiral effect of zinc complexes encephalitis.Chem.Pharm.Bull,1962,(10):1254
[5]张有明,白俊锋,吕曼青等.氨基酸锌的制备和性质[J].化学世界,1997,(2):82-84
[6]朱妙琴.甘氨酸合铜(Ⅱ)配合物的固、液相反应合成与表征[J].光谱实验室,2006,23(1):110-114
[7]张瑞华.赖氨酸锌的合成[J].饲料工业,2004,25(5):35-37
[8]蒋才武,陈超球,梁利芳等.微波辐射条件下Cu(Ⅱ)、Co(Ⅱ)、Ni(Ⅱ)、Zn(Ⅱ)与甘氨酸配合物的固相合成、表征及应用[J].广西师范学报(自然科学版),2000,17(1):32-37
[9]柴之芳,祝汉民.微量元素化学概论[M].北京:原子能出版社,1994
[10]刘建睿,侯育冬,高胜利等.锌盐与L-α-组氨酸配合物行为的相化学研究[J].化学学报,1999,57:485-490
[11]游效曾.配位化合物的结构和性质[M].北京:中国科学出版社,1992
[1]杨频,高飞.生物无机化学原理[M].北京:科学出版社,2002
[2]孔祥瑞.必需微量元素营养,生理及临床意义[M].安徽:安徽科技出版社,1982
[3]阮景军.微量元素铜、锌与细胞免疫关系的研究进展[J].国外医学免疫学分册,1994,(6):308-310
[4]考希宾,王治伦,高艳.微量元素锌和人体健康[J].中国地方病防止杂志,2007,22(3):192-194
[5]MacDonald R S.The role of zinc in growth and cell proliferation[J].Nutr,2000,130(5):1500-1508
[6]Wang X,Fosmire GJ,Gay CV.Short-term zinc de-ficiency inhibits chondrocyte proliferation and induces celll apop to sis in the epiphyseal growth plate of young chieken[J].Nutr,2002,132(4):665-673
[7]Wong W Y.Effects of folic acid and zinc sulfate on male factor subfertility.A double-blind,randomized,placebo-controlled trial[J].Fertility and Sterility,2002,77(3):491-498
[8]曹锡章,宋天佑,王杏乔.无机化学-第三版[M].北京:高等教育出版社,1994:1148
[9]Gdragulesscu,iulia Havlik,Ana mourer.Compausi coodinativi cu autivilate potential antitumorala.Ⅳ.Complessi de aminoacizi.Farmacia,Vot ⅩⅩⅧ,nr,3,anul,1980:139
[10]Hill CH.Interrelationships of selenium with other trace elements[J].Federation Proceeding,1975,34(11):2096
[11]Marijana Matek Sari'c.Effect of dietary calcium on cadmium absorption and retention in suckling rats[J].BioMetals,2002,(15):175-182
[12]王爱娜,杨在宾,周连明.氨基酸微量元素螯合物的研究进展[J].中国饲料,2004,(18):28-29
[13]张朝平,张炜.某些蛋白质同银(Ⅰ)-铜(Ⅱ)离子配合物的IR、Raman和UV/VIS 光谱研究[J].化学试剂,1999,21(1):11-4
[14]Daimay Lin-Vien,Norman B.Colthup,William G.Fateley,Jeanette G.Grasselli.The Handbook of Infrared and Raman Characcteristic Frequencies of Organic Molecules[M].New York.Harcourt Brace Jovanovich,Publishers,1991:115
[15]G.Socarates.Infrared Characteristic Group Frequencies[M].New York.A Wiley-Interscience Publication,1980:55
[16]中本一雄.无机和配位化合物的红外和拉曼光谱[M].北京.化学工业出版社,1986:316
[17]柯以侃,董慧茹.分析化学手册-第三分册光谱分析(第二版)[M].北京.化学工业出版社,1998:928-1075
[18]T.Balakrishnan,K.Ramamurthi.Growth,structural,optical,thermal and mechanical properties of glycine zinc chloride single crystal[J].Materials letters,2008,62:65-68
[19]Mario Tulio S.Rosado,Maria Leonor R.S.Duarte,Rui Fausto.Vibrational spectra (FT-IR,Raman and MI-IR)ofα-and β-alanine[J].Journal of Molecular Structure,1997,410-411:343-348
[20]Santosh Kumar,Amareshwar Kumar Rai,S.B.Rai,D.K.Rai,A.N.Singh,V.B Singh.Infrared,Raman and electronic spectra of alanine:A comparison with ab intio calculation[J].Journal of Molecular Structure,2006,791:23-29
[21]Jan Vanco,Jaromir Marek,Zdenek Travnicek,Eva Racanska,Jan Muselik,Ol'ga Svajlenova.Synthesis,structural characterization,antiradical and antidiabetie activities of copper(Ⅱ)and zinc(Ⅱ)Schiff base complexes derived from salicylaldehyde and β-alanine[J].Journal of Inorganic Biochemistry,2007:1-11
[22]M.R.Suresh Kumar,H.J.Ravindra,A.Jayarama,S.M.Dharmaprakash.Structural characteristics and second harmonic generation in L-threonine crystals[J].Journal of Crystal Growth,2006,286:451-456
[23]G.Ramesh Kumar,S.Gokul Raj,R.Mohan,R.Jayavel.Growth,structural and spectral analyses of nonlinear optical L-threonine single crystals[J].Journal of Crystal Growth,2005,275:e1947-e1951
[24]游效曾.配位化合物的结构和性质[M].北京:科学出版社,1992:233-257
[25]王瑞瑶,高峰,金天柱.稀土-氨基酸配合物的结构化学[J].化学通报,1996,10:14-20
[26]张祥麟.配合物化学[M].北京:高等教育出版社,1991:194-200
[27]Dean J.A.Lange's Handbook of Chemistry(Thirteenth Edition)[M].New York:McGraw-Hill Book Company,1985
[28]刘文涵,单伟光,高云芳等.硫化锌法原子吸收间接测定谷氨酸络和反应的机理研究[J].光谱学与光谱分析,2003,23(6):1191-1193
[29]刘文涵,单胜燕,张丹等.硫化锌法原子吸收间接测定半胱氨酸络和反应的机理研究[J].光谱学与光谱分析,2005,25(10):1717-1719
[30]刘文涵,张丹,郑建珍等.硫化锌法原子吸收间接测定精氨酸络和反应的机理研究[J].光谱学与光谱分析,2006,26(1):147-150
[31]Lingtao Yu,Ipsita A.Banerjee,Hiroshi Matsui.Incorporation of sequenced peptides on nanotubes for Pt coating:smart control of nucleation and morphology via activation of metal binding sites on amino acids[J].J Mater.Chem.,2004,14(4):739-743
[32]David S.Auld.Zinc coordination sphere in biochemical zinc sites[J].BioMetals 2001,14:271-313
[33]Arthur W.Adamson,William L.Waltz,Edoardo Zinato etc.Photochemistry of Transition-Metal Coordination Compounds[M].580
[34]童金强,颜承农.硫酸根离子配位方式的群论研究[J].荆州师专学报(自然科学版),1995,18(5):74-76
[35]侯育冬,高胜利,郭利娟等.硫酸锌与L-α-氨基酸配合行为的相化学研究[J].高等化学学报,1999,20(9):1346-1348
[36]高胜利,陈三平,李焕勇等.硫酸锌与α-氨基酸的相化学及其新相的合成和表征[J].化学研究与应用,2002,14(3):304-307
[37]黄在银,谭学才,文红云.硫酸锌与左旋酪氨酸配合物的合成及测定[J].广西民族学院学报(自然科学版),2003,9(2):28-29
[38]胡宗元,李良超,程孟琪.硝酸根离子配位方式的群论解析[J].安顺师专学报,1999,4:71-73
[39]高胜利,侯育冬,刘建睿等.硝酸锌与三种氨基酸配合行为的相化学研究[J].化学学报,2000,58(1):65-70
[40]高胜利,冀棉,刘建睿,侯育冬,陈三平.硝酸稀土组氨酸配合物的拉曼光谱研究[J].光谱学与光谱分析,1999,19(6):814-816
[41]李月琴,冀棉,王志海等.硝酸镝与L-组氨酸配合物的拉曼光谱研究[J].西北地质,1998,19(3):51-53
[42]丁邦东,顾仁敖.稀土金属有机配合物的红外和拉曼光谱研究[J].中国稀土学报,2001,19(6):552-554
[43]张维平,何水样,赵旭东.稀土硝酸盐与咪唑、丙氨酸配合物的合成及表征[J].宝鸡文理学院学报(自然科学版),2002,22(3):187-190
[1]Abrams M J,Murrer B A.Metal compounds in therapy and diagnosis[J].Science,1993,261:725
[2]陈丹丹,张涛,任丽萍.金属及其配合物与生物分子相互作用机理的研究进展[J].分析科学学报,2006,22(5):600-604
[3]吴刚,牟永平,和彦苓等.金属及金属配合物在医学中的作用[J].包头医学院学报,2004,20(1):1-3
[4]高胜利,侯育冬,冀棉等.锌盐与α-氨基酸配合物的XPS的研究[J].光谱学与光谱分析,2001,21(1):81-83
[5]计亮年,黄锦汪,莫庭焕.生物无机化学导论第二版[M].广州:中山大学出版社,2001:208
[6]杨频主编.生物无机化学导论[M].西安:西安交通大学出版社,1991:289
[7]杨坡,王选年,李敬玺.氨基酸螯合铜在动物生产中的应用[J].动物医学进展,2006,27(9):46-50
[8]杨频,高飞.生物无机化学原理[M].北京:科学出版社,2002
[9]Daimay Lin-Vien,Norman B.Colthup,William G.Fateley,Jeanette G.Grasselli.The Handbook of Infrared and Raman Characcteristic Frequencies of Organic Molecules[M].New York.Harcourt Brace Jovanovich,Publishers,1991:115
[10]G.Socarates.Infrared Characteristic Group Frequencies[M].New York.A Wiley-Interscience Publication,1980:55
[11]中本一雄.无机和配位化合物的红外和拉曼光谱[M].北京.化学工业出版社,1986:316
[12]柯以侃,董慧茹.分析化学手册-第三分册光谱分析(第二版)[M].北京.化学工业出版社,1998.928-1075
[13]许良忠,文丽荣.过渡金属-甘氨酸配合物的IR光谱[J].光谱实验室,2002,19(5):641-643
[14]周晓华,李明华,乐学义.邻菲罗啉-氨基酸铜(Ⅱ)配合物的合成及表征[J].合成化学,1999,7(2):213-215
[15]余建平,罗国添,简连花等.新型L-半胱氨酸尾式卟啉铜(Ⅱ)配合物的合成与表征[J].赣南师范学院学报,2003,(6):27-28
[16]翁家宝,刘称峰,郑学琳等.氨基酸侧基对Cu(Ⅲ)-L-氨基酸配合物结构特征的影响[J].福建师范大学学报(自然科学版),2002,18((4):50-55
[17]Bi Yu,Wei-Jan Huang,Peter Wen-Shyg Chiou.Bioavailability of iron from amino acid complex in weanling pigs[J].Animal Feed Science and Technology,2000,86:39-52
[18]刘京萍,李金,葛兴.模拟金属酶-铁(Ⅱ)酪氨酸配合物的合成及SOD样活性[J].北京联合大学学报(自然科学版),2003,17(3):40-43
[19]岳松.半胱氨酸合铁(Ⅱ)晶体的制备及结构表征[J].化学研究与应用,2000,12(4):387-389
[20]程荷凤,李小凤,东野广智等.化橘红多糖铁(Ⅳ)配合物的合成、理化性质及表面结构的研究[J].中国医药工业杂志,2000,31(9):394-396
[21]林纪筠,杨维达.铜(Ⅱ)/铁(Ⅲ)Slaen双核配合物的再研究[J].无机化学学报,1995,11(2):126-129
[22]韦凤仙,谭黎明峰,蒋毅民.铜(Ⅱ)、铁(Ⅲ)与吡啶-2,6-二甲酸、L-谷氨酸三元配合物的合成与表征[J].广西师范大学学报(自然科学版),1999,17(1):84-87
[23]朱文祥主编.中级无机化学[M].北京:高等教育出版社,2004:459-469
[2]刘树祥,刘春丽,田来进.锌(Ⅱ)-氨基酸水杨醛席夫碱-α-氨基酸三元配合物的稳定性[J].无机化学学报,1999,15(1):114-117
[3]高恩君,刘瑕,刘祁涛.钯(Ⅱ)-芳香氮碱一氨基酸三元配合物中的电子效应和 芳环堆积作用[J].无机化学学报,2002,18(2):442-446
[4]王则民,杨海峰,王桂华等.稀土脯氨酸邻菲哕啉固体配合物合成和表征[J].无机化学学报,1999,15(6):721-726
[5]计亮年,黄锦汪,莫庭焕.生物无机化学导论第二版[M].广州.中山大学出版社,2001.208
[6]邵建华,韩永圣,高芝祥.复合氨基酸稀土元素螯合物的生产和应用研究进展[J].稀土,2001,22(5):59-62
[7]J.Legendziewicz,E.Huskowska.Application of luminescence and absorption spectroscopy and x-ray methods to studies of Ln~(+3)ions interaction with aminoacids[J].Inorganica Chimica Acta,1984,95(2):57-63
[8]许良忠,文丽荣.过渡金属-甘氨酸配合物的IR光谱[J],光谱实验室,2002,19(5):641-643
[9]丁邦东,顾仁敖.稀土金属有机配合物的红外和拉曼光谱研究[J],中国稀土学报,2001,19(6):552-554
[10]张朝平,张炜.某些蛋白质同银(Ⅰ)-铜(Ⅱ)离子配合物的IR、Raman和UV/VIS 光谱研究[J],化学试剂,1999,21(1):11-14
[11]S.Jarmelo,P.R.Carey,R.Fausto.The Raman Spectra of sreine and 3,3-dideutero-serine in aqueous solution[J],Vibrational Spectroscopy,2007,43:104-110
[12]高胜利,侯育冬,冀棉等.锌盐与α-氨基酸配合物的XPS的研究[J],光谱学与光谱分析,2001,21(1):81-83
[13]蒋才武,陈超球,陈灵.微波辐射下苯氧乙酸锌、甘氨酸锌的固相合成及表征[J],广西科学,1999,6(3):193-196
[14]潘家来编著,激光拉曼光谱在有机化学上的应用[M],北京:化学工业出版社,1986
[15]柯以侃,董慧茹.分析化学手册第三分册:光谱分析[M],北京:化学工业出版社,1998
[16]游效曾.配位化合物的结构和性质[M],北京:科学出版社,1992:233
[17]王阳,吴晓斌,王佳等.近场拉曼光谱在纳米结构表征中的应用[J].光谱学与光谱分析,2006,26(7):1253-1259
[18]黄海平,田英芬,何尚锦等.拉曼光谱在高分子中的应用新进展[J].热固性树脂,2001,16(2):38-44
[19]张树霖.简介生物学领域中的拉曼散射研究[J].光散射学报,1995,7(1):47-51
[20]余国滔.拉曼光谱在医学上的应用(Ⅰ)[J].光散射学报,1996,8(2):113-122
[21]李灿,李美俊.拉曼光谱在催化研究中应用的进展[J].分子催化,2003,17(3):213-240
[22]杨春艳.红外光谱在腐蚀研究中的应用与发展[J].腐蚀与防腐,2001,22(10):434-440
[23]黄卫宁,张君慧,R.C.Hoseney.FT-Raman光谱与谷物化学研究的最新进展[J].食品科学,2004,25(11):411-415
[24]庞新安.近红外光谱技术及其在农产品品质分析中的应用[J].广西农业生物科学,2007,26(1):83-87
[25]王吉有,王闵,刘玲.拉曼光谱在考古中的应用[J].光散射学报,2006,18(2):130-133
[26]王昶.波谱分析技术在宝石鉴定中的应用评述[J].光谱实验室,2001,18(3):301-303
[27]张鹏翔,赵金涛,杨延勇.显微拉曼技术在公安法学中的应用[J].光散射学报,1998,1(10):3-4
[28]陈丹丹,张涛,任丽萍.金属及其配合物与生物分子相互作用机理的研究进展[J].分析科学学报,2006,22(5):600-604
[29]陈燕青,戴立益,杨宝林等.稀土组氨酸配合物的合成和性质研究[J].化学世界,1996,8(3):353-358
[30]陈芳,胡珍珠,石鹤等.稀土与L-亮氨酸、咪唑三元配合物的合成及抑菌作用研究[J].稀有金属,2006,29(3):311-314
[31]Sumiyuki Akihama,Shigeshi Togoshima.Chemotherapeutic drags against viruses ⅩⅩⅪⅤ.Aativiral effect of zinc complexes encephalitis.Chem.Pharm.Bull,1962,(10):1254
[32]张瑞华.赖氨酸锌的合成[J].饲料工业,2004,25(5):35-37
[33]朱妙琴.甘氨酸合铜(Ⅱ)配合物的固、液相反应合成与表征[J].光谱实验室,2006,23(1):110-114
[34]蒋才武,陈超球,梁利芳等.微波辐射条件下Cu(Ⅱ)、Co(Ⅱ)、Ni(Ⅱ)、Zn(Ⅱ)与甘氨酸配合物的固相合成、表征及应用[J].广西师范学报(自然科学版),2000,17(1):32-37
[35]柴之芳,祝汉民.微量元素化学概论[M].北京:原子能出版社,1994
[36]刘建睿,侯育冬,高胜利等.锌盐与L-α-组氨酸配合物行为的相化学研究[J].化学学报,1999,57:485-490
[37]屈景年,刘义,曾荣英等.L-胱氨酸合锌(Ⅱ)钠的热化学[J].化学研究与应用,2004,16(3):386-87
[38]屈景年,刘义,涂麟俊等.L-丙氨酸和L-组氨酸与铜离子混配合物的热化学[J].化学通报,2002,(11):786-790
[39]高胜利,冀棉,刘建睿等.稀土硝酸盐与组氨酸配合物的研究[J].中国科学(B 辑),1999,29(3):264-272
[40]俞志刚,李锦州,刘双全等.二苯基呋喃甲酰基吡唑啉酮及其金属配合物的合成与电化学行为[J].应用化学,2004,21(12):1300-1304
[41]童叶翔,康北笙,杨绮琴.金属配位化合物溶液的电化学研究[J].电化学,1999,5(4):361-370
[42]Watters J I,Dewitt R,J.Am.Chem.Soc.1960,82:1333
[43]何美,周华峰,谢颖等.铜-二肽(氨基酸)二元配合物的稳定性研究[J],沈阳化工学院学报,2003,17(1):7-11
[44]许鹏奎.铜[Cu(Ⅱ)]-氨基酸配合物稳定常数的测定[J],甘肃教育学院学报(自然科学版),1999,13(2):49-51
[45]刘文涵,单胜艳,张丹等.硫化锌法原子吸收间接测定半胱氨酸络合物稳定常数[J],光谱学与光谱分析,2005,25(11):1872-1874
[46]卢小泉,康敬万,高锦章编著.配合物电分析化学[M].北京:中国石化出版社,2000:120
[47]刘伟明,刘巨涛,冷红霞等.L-赖氨酸锌配合物结构的理论研究[J],分子科学学报,2001,17(4):247-250
[48]刘文涵,王丽丽,李祖光等.数值拟合研究原子吸收间接测定谷氨酸的机理[J],浙江工业大学学报,2004,32(6):615-619
[49]刘宗怀,张孟民,宋迪生等.稀土硝酸盐甘氨酸固体配合物的合成及杀菌活性 试验[J],稀土,1995,16(3):5-8
[50]杨频.生物无机化学导论[M].西安:西安交通大学出版社,1991:299
[51]王则民,杨海峰,王桂华等.稀土脯氨酸邻菲啰啉固体配合物合成和表征[J].无机化学学报,1999,15(6):721-726
[52]范镇基.氨基酸络合物应用新进展[J].广东科技,1997,2:10-11
[53]王瑞瑶,金天柱,郑智平.镧系元素配位化学新领域[J].化学学报,2000,58(12):1481-1492
[54]邵建华,韩永圣,高芝祥.复合氨基酸稀土元素螯合物的生产和应用研究进展[J].稀土,2001,22(5):59-62
[55]Miguel Machuqueiro,Tamis Darbre.Zinc mediated methyl transfer from trimethyl phosphate to chelating and non-chelating alkyl tiiols.Model for Zn-dependent methytransferases[J].Inorganin Biochemistry,2003,94:193-196
[56]Gunilla U.M.Lindstrom,Erik Johansson,Martin Nygren.Quality assurance of multivariate analytical measurements by principal components analysis[J].Chemosphere,1985,14:1695-1701
[57]王文韵,曾广赋.我国分子光谱的发展史[J].光谱学与光谱分析,1983,3(1):5-14
[58]乔冬平.浅谈傅立叶变换红外光谱技术的进展及其应用[J].材料开发与应用,1999,14(1):44-46
[59]刘敏娜,王桂清,卢其斌.红外光谱技术的进展及其应用[J].精细化工中间体,2001,31(6):9-12
[60]梁齐治.红外光谱在真伪鉴别上的应用[J].北京联合大学学报,2000,14(2):69-74
[61]何晓东,汤河源,徐新.FT-IR显微红外光谱图像系统及其应用[J].现代仪器使用与维修,1999(2):32-34
[62]EKGASITS,ISHIDAH.New optical depth-profiling technique by use of the multiple-frequency approach with single ATR FT-IR spectrum:theoretical development[J].Applied Spectroscopy,1997,51(10):1488-1495
[63]李淑玲.拉曼光谱仪及其应用进展[J].岩矿测试,1998,17(4):312-316
[64]M.Fleischmann,P.J.Hendra,A.J.McQuillan.Raman Spectra of pyridine adsorbed at a silver electrode[J].Chemical Physics Letters,1974,26(2):163-166
[65]刘玲.激光拉曼光谱及其应用进展[J].山西大学学报(自然科学版),2001,24(3):279-282
[66]于世林,李寅蔚主编.波谱分析法[M].重庆:重庆大学出版社,1994,91-94
[67]中本一雄.无机和配位化合物的红外和拉曼光谱[M].北京:化学工业出版社,1991,8-32
[68]Nodal I.Generalized Tow-dimensional Correlation Method Applicable to Infrared Raman and other Types of Spectroscopy[J].Appl Spectrosc,1993,47:1239
[69]Aust Jeffrey F,Booksh Karl S,Stellman Christopher M.Precise Determination of Percent of Epoxide Polymers and Composites via Fiber-Optie Raman Spectroscopy and Multivariate Analysis[J].Appl Spectrosc,1997,51(3):247-250
[70]Stellman Christopher M,Aust Jeffrey F,Myrik Michael L.In Situ Spectroscopy Study of Microwave Polymerization[J].Appl Spectrosc,1995,49(3):392-394.
[71]褚明福,邹乐西,仲敬荣.拉曼和红外光谱在核材料研究中的应用[J].稀有金属,2005,29(1):106-111
[72]Sun J S,Michaelian K H.Surface-Enhanced Raman Scattering of Acrylamide and Polyacrylamide Adsorbed on Silver Colloid Surface:Polymerization of acrylamide on silver[J].J.RamanSpectroscopy,1987,18(6):409-414
[73]Heine T.M.,Ahern A.M.,Garrell R.L.Surface-enhanced Raman spectroscopy of peptides:preferential N-terminal adsorption on colloidal silver[J].J.Am.Chem.Soc.,1991,113(3):846-854
[74]Sang Kyu Kim,Myung Soo Kim,Se Won Suh.Surface-Enhanced Raman Scattering of Aromatic Amino Acid and Their Glycyl Dipeptides in Silver Sol[J].J.Raman Spectroscopy,1987,18(3):171-175
[75]孙素琴,郁鉴源,胡鑫尧.分子光谱法无损鉴别生药材的最新进展[J].光谱学与光谱分析,1999,19(6):841-843
[76]孙素琴,周群,郁鉴源.分子振动光谱法与中药研究的最新进展[J].光谱学与光谱分析,2000,20(2):199-202
[77]李如璧.激光拉曼光谱技术在宝石鉴定中的应用[J].常州技术师范学院学报,2001,7(2):1-5
[78]祖恩东,段云彪,张鹏翔.显微共焦拉曼光谱在宝石鉴定中的应用[J].云南大学学报,2004,26(1):51-55
[79]王怡林,杨群,张鹏翔等.元代铜镜腐蚀情形的拉曼光谱研究[J].光谱学与光谱分析,2002,22(1):48-50
[80]杨群,王怡林,张鹏翔等.武定恐龙化石的显微拉曼光谱研究[J].光谱学与光谱分析,2002,22(5):793-795
[81]钱晓凡,施英,张鹏翔等.枪击残留物拉曼光谱研究[J].光散射学报,2001,13(1):45-48
[82]刘国志,赵金涛,徐存英等.麻黄素和左旋咪唑显微拉曼测试分析[J].光谱学与光谱分析,2002,22(2):248-250
[83]赵金涛,徐存英,段云彪等.痕迹走私海洛因显微拉曼测试分析[J].光谱学与光谱分析,2002,22(4):588-590
[84]药林桃,刘木华,刘道金等.激光技术在农产品质量检测中的研究进展[J].激光生物学报,2007,16(3):369-373
[85]Wachs I E.Characterization of Catalytic Materials[M].Boston:Butterworth-Heinemann,1992
[86]Krylov O V,Mamedov A Kh,Mirzabekova S R.New Development in Selective Oxidation[M].Amsterdam:Elsevier,1994
[87]薛奇.红外傅里叶变换反射吸收光谱的原理及金属表面涂层结构的表征[J].化学通报,1989,(12):33-35
[1]杨频,高飞.生物无机化学原理[M].北京:科学出版社,2002
[2]计亮年,黄锦汪,莫庭焕等.生物无机化学导论第二版[M].广州:中山大学出版社,2001
[3]蒋滢主编.氨基酸的应用[M].北京:世界图书出版公司,1996:5-7
[4]Sumiyuki Akihama,Shigeshi Togoshima.Chemotherapeutic drags against viruses ⅩⅩⅪⅤ.Aativiral effect of zinc complexes encephalitis.Chem.Pharm.Bull,1962,(10):1254
[5]张有明,白俊锋,吕曼青等.氨基酸锌的制备和性质[J].化学世界,1997,(2):82-84
[6]朱妙琴.甘氨酸合铜(Ⅱ)配合物的固、液相反应合成与表征[J].光谱实验室,2006,23(1):110-114
[7]张瑞华.赖氨酸锌的合成[J].饲料工业,2004,25(5):35-37
[8]蒋才武,陈超球,梁利芳等.微波辐射条件下Cu(Ⅱ)、Co(Ⅱ)、Ni(Ⅱ)、Zn(Ⅱ)与甘氨酸配合物的固相合成、表征及应用[J].广西师范学报(自然科学版),2000,17(1):32-37
[9]柴之芳,祝汉民.微量元素化学概论[M].北京:原子能出版社,1994
[10]刘建睿,侯育冬,高胜利等.锌盐与L-α-组氨酸配合物行为的相化学研究[J].化学学报,1999,57:485-490
[11]游效曾.配位化合物的结构和性质[M].北京:中国科学出版社,1992
[1]杨频,高飞.生物无机化学原理[M].北京:科学出版社,2002
[2]孔祥瑞.必需微量元素营养,生理及临床意义[M].安徽:安徽科技出版社,1982
[3]阮景军.微量元素铜、锌与细胞免疫关系的研究进展[J].国外医学免疫学分册,1994,(6):308-310
[4]考希宾,王治伦,高艳.微量元素锌和人体健康[J].中国地方病防止杂志,2007,22(3):192-194
[5]MacDonald R S.The role of zinc in growth and cell proliferation[J].Nutr,2000,130(5):1500-1508
[6]Wang X,Fosmire GJ,Gay CV.Short-term zinc de-ficiency inhibits chondrocyte proliferation and induces celll apop to sis in the epiphyseal growth plate of young chieken[J].Nutr,2002,132(4):665-673
[7]Wong W Y.Effects of folic acid and zinc sulfate on male factor subfertility.A double-blind,randomized,placebo-controlled trial[J].Fertility and Sterility,2002,77(3):491-498
[8]曹锡章,宋天佑,王杏乔.无机化学-第三版[M].北京:高等教育出版社,1994:1148
[9]Gdragulesscu,iulia Havlik,Ana mourer.Compausi coodinativi cu autivilate potential antitumorala.Ⅳ.Complessi de aminoacizi.Farmacia,Vot ⅩⅩⅧ,nr,3,anul,1980:139
[10]Hill CH.Interrelationships of selenium with other trace elements[J].Federation Proceeding,1975,34(11):2096
[11]Marijana Matek Sari'c.Effect of dietary calcium on cadmium absorption and retention in suckling rats[J].BioMetals,2002,(15):175-182
[12]王爱娜,杨在宾,周连明.氨基酸微量元素螯合物的研究进展[J].中国饲料,2004,(18):28-29
[13]张朝平,张炜.某些蛋白质同银(Ⅰ)-铜(Ⅱ)离子配合物的IR、Raman和UV/VIS 光谱研究[J].化学试剂,1999,21(1):11-4
[14]Daimay Lin-Vien,Norman B.Colthup,William G.Fateley,Jeanette G.Grasselli.The Handbook of Infrared and Raman Characcteristic Frequencies of Organic Molecules[M].New York.Harcourt Brace Jovanovich,Publishers,1991:115
[15]G.Socarates.Infrared Characteristic Group Frequencies[M].New York.A Wiley-Interscience Publication,1980:55
[16]中本一雄.无机和配位化合物的红外和拉曼光谱[M].北京.化学工业出版社,1986:316
[17]柯以侃,董慧茹.分析化学手册-第三分册光谱分析(第二版)[M].北京.化学工业出版社,1998:928-1075
[18]T.Balakrishnan,K.Ramamurthi.Growth,structural,optical,thermal and mechanical properties of glycine zinc chloride single crystal[J].Materials letters,2008,62:65-68
[19]Mario Tulio S.Rosado,Maria Leonor R.S.Duarte,Rui Fausto.Vibrational spectra (FT-IR,Raman and MI-IR)ofα-and β-alanine[J].Journal of Molecular Structure,1997,410-411:343-348
[20]Santosh Kumar,Amareshwar Kumar Rai,S.B.Rai,D.K.Rai,A.N.Singh,V.B Singh.Infrared,Raman and electronic spectra of alanine:A comparison with ab intio calculation[J].Journal of Molecular Structure,2006,791:23-29
[21]Jan Vanco,Jaromir Marek,Zdenek Travnicek,Eva Racanska,Jan Muselik,Ol'ga Svajlenova.Synthesis,structural characterization,antiradical and antidiabetie activities of copper(Ⅱ)and zinc(Ⅱ)Schiff base complexes derived from salicylaldehyde and β-alanine[J].Journal of Inorganic Biochemistry,2007:1-11
[22]M.R.Suresh Kumar,H.J.Ravindra,A.Jayarama,S.M.Dharmaprakash.Structural characteristics and second harmonic generation in L-threonine crystals[J].Journal of Crystal Growth,2006,286:451-456
[23]G.Ramesh Kumar,S.Gokul Raj,R.Mohan,R.Jayavel.Growth,structural and spectral analyses of nonlinear optical L-threonine single crystals[J].Journal of Crystal Growth,2005,275:e1947-e1951
[24]游效曾.配位化合物的结构和性质[M].北京:科学出版社,1992:233-257
[25]王瑞瑶,高峰,金天柱.稀土-氨基酸配合物的结构化学[J].化学通报,1996,10:14-20
[26]张祥麟.配合物化学[M].北京:高等教育出版社,1991:194-200
[27]Dean J.A.Lange's Handbook of Chemistry(Thirteenth Edition)[M].New York:McGraw-Hill Book Company,1985
[28]刘文涵,单伟光,高云芳等.硫化锌法原子吸收间接测定谷氨酸络和反应的机理研究[J].光谱学与光谱分析,2003,23(6):1191-1193
[29]刘文涵,单胜燕,张丹等.硫化锌法原子吸收间接测定半胱氨酸络和反应的机理研究[J].光谱学与光谱分析,2005,25(10):1717-1719
[30]刘文涵,张丹,郑建珍等.硫化锌法原子吸收间接测定精氨酸络和反应的机理研究[J].光谱学与光谱分析,2006,26(1):147-150
[31]Lingtao Yu,Ipsita A.Banerjee,Hiroshi Matsui.Incorporation of sequenced peptides on nanotubes for Pt coating:smart control of nucleation and morphology via activation of metal binding sites on amino acids[J].J Mater.Chem.,2004,14(4):739-743
[32]David S.Auld.Zinc coordination sphere in biochemical zinc sites[J].BioMetals 2001,14:271-313
[33]Arthur W.Adamson,William L.Waltz,Edoardo Zinato etc.Photochemistry of Transition-Metal Coordination Compounds[M].580
[34]童金强,颜承农.硫酸根离子配位方式的群论研究[J].荆州师专学报(自然科学版),1995,18(5):74-76
[35]侯育冬,高胜利,郭利娟等.硫酸锌与L-α-氨基酸配合行为的相化学研究[J].高等化学学报,1999,20(9):1346-1348
[36]高胜利,陈三平,李焕勇等.硫酸锌与α-氨基酸的相化学及其新相的合成和表征[J].化学研究与应用,2002,14(3):304-307
[37]黄在银,谭学才,文红云.硫酸锌与左旋酪氨酸配合物的合成及测定[J].广西民族学院学报(自然科学版),2003,9(2):28-29
[38]胡宗元,李良超,程孟琪.硝酸根离子配位方式的群论解析[J].安顺师专学报,1999,4:71-73
[39]高胜利,侯育冬,刘建睿等.硝酸锌与三种氨基酸配合行为的相化学研究[J].化学学报,2000,58(1):65-70
[40]高胜利,冀棉,刘建睿,侯育冬,陈三平.硝酸稀土组氨酸配合物的拉曼光谱研究[J].光谱学与光谱分析,1999,19(6):814-816
[41]李月琴,冀棉,王志海等.硝酸镝与L-组氨酸配合物的拉曼光谱研究[J].西北地质,1998,19(3):51-53
[42]丁邦东,顾仁敖.稀土金属有机配合物的红外和拉曼光谱研究[J].中国稀土学报,2001,19(6):552-554
[43]张维平,何水样,赵旭东.稀土硝酸盐与咪唑、丙氨酸配合物的合成及表征[J].宝鸡文理学院学报(自然科学版),2002,22(3):187-190
[1]Abrams M J,Murrer B A.Metal compounds in therapy and diagnosis[J].Science,1993,261:725
[2]陈丹丹,张涛,任丽萍.金属及其配合物与生物分子相互作用机理的研究进展[J].分析科学学报,2006,22(5):600-604
[3]吴刚,牟永平,和彦苓等.金属及金属配合物在医学中的作用[J].包头医学院学报,2004,20(1):1-3
[4]高胜利,侯育冬,冀棉等.锌盐与α-氨基酸配合物的XPS的研究[J].光谱学与光谱分析,2001,21(1):81-83
[5]计亮年,黄锦汪,莫庭焕.生物无机化学导论第二版[M].广州:中山大学出版社,2001:208
[6]杨频主编.生物无机化学导论[M].西安:西安交通大学出版社,1991:289
[7]杨坡,王选年,李敬玺.氨基酸螯合铜在动物生产中的应用[J].动物医学进展,2006,27(9):46-50
[8]杨频,高飞.生物无机化学原理[M].北京:科学出版社,2002
[9]Daimay Lin-Vien,Norman B.Colthup,William G.Fateley,Jeanette G.Grasselli.The Handbook of Infrared and Raman Characcteristic Frequencies of Organic Molecules[M].New York.Harcourt Brace Jovanovich,Publishers,1991:115
[10]G.Socarates.Infrared Characteristic Group Frequencies[M].New York.A Wiley-Interscience Publication,1980:55
[11]中本一雄.无机和配位化合物的红外和拉曼光谱[M].北京.化学工业出版社,1986:316
[12]柯以侃,董慧茹.分析化学手册-第三分册光谱分析(第二版)[M].北京.化学工业出版社,1998.928-1075
[13]许良忠,文丽荣.过渡金属-甘氨酸配合物的IR光谱[J].光谱实验室,2002,19(5):641-643
[14]周晓华,李明华,乐学义.邻菲罗啉-氨基酸铜(Ⅱ)配合物的合成及表征[J].合成化学,1999,7(2):213-215
[15]余建平,罗国添,简连花等.新型L-半胱氨酸尾式卟啉铜(Ⅱ)配合物的合成与表征[J].赣南师范学院学报,2003,(6):27-28
[16]翁家宝,刘称峰,郑学琳等.氨基酸侧基对Cu(Ⅲ)-L-氨基酸配合物结构特征的影响[J].福建师范大学学报(自然科学版),2002,18((4):50-55
[17]Bi Yu,Wei-Jan Huang,Peter Wen-Shyg Chiou.Bioavailability of iron from amino acid complex in weanling pigs[J].Animal Feed Science and Technology,2000,86:39-52
[18]刘京萍,李金,葛兴.模拟金属酶-铁(Ⅱ)酪氨酸配合物的合成及SOD样活性[J].北京联合大学学报(自然科学版),2003,17(3):40-43
[19]岳松.半胱氨酸合铁(Ⅱ)晶体的制备及结构表征[J].化学研究与应用,2000,12(4):387-389
[20]程荷凤,李小凤,东野广智等.化橘红多糖铁(Ⅳ)配合物的合成、理化性质及表面结构的研究[J].中国医药工业杂志,2000,31(9):394-396
[21]林纪筠,杨维达.铜(Ⅱ)/铁(Ⅲ)Slaen双核配合物的再研究[J].无机化学学报,1995,11(2):126-129
[22]韦凤仙,谭黎明峰,蒋毅民.铜(Ⅱ)、铁(Ⅲ)与吡啶-2,6-二甲酸、L-谷氨酸三元配合物的合成与表征[J].广西师范大学学报(自然科学版),1999,17(1):84-87
[23]朱文祥主编.中级无机化学[M].北京:高等教育出版社,2004:459-469