神经心理因素对针药结合治疗贝尔麻痹疗效影响的临床观察
|
摘要
目的：
本临床观察是国家重点基础研究发展计划“经穴效应特异性及影响因素研究”(课题编号：2006CB504502)之子课题“针刺治疗贝尔麻痹中得气和神经心理因素对针刺效应影响的多中心随机对照试验”的一部分。本研究通过治疗50例贝尔麻痹患者,以针药结合治疗贝尔麻痹的临床疗效为切入点,以卡特尔人格因素测验和划消测验为方法,观察研究神经心理因素对临床针刺疗效的影响,以初步探讨经穴效应规律。
方法：
1、临床资料该临床观察研究病例是从2009年3月至2010年9月湖北省中医院的门诊和住院患者中筛选出的50例患者,患者按要求进行16PF和划消测验,记录的各个量表的分数,以这些分数作为神经心理因素的度量值。将16PF测验得分转化为标准分后按对应的公式计算出四种可以形容人格类型的次级因素(称二元人格特征)的得分,划消测验根据对应的计算公式计算出工作效率得分,将患者按照得分高低分为对应的低分组、中分组和高分组进行观察分析。患者均给以相同的药物治疗,强的松片：30mg qd×7天,20mg qd×4天,10mg qd×3天；维生素B1针：0.1,肌注,×14天；甲钻胺(弥可保)针：0.5mg,肌注,×14天；14天后,口服维生素B1片：20mg, tid;甲钴铵(弥可保)片：0.5mg, tid。各组在发病后至入选第4周均采用相同穴位进行针刺治疗。
2、治疗效果观察时间观察记录临床症状与入组第一天及治疗四个疗程后及相关量表指标于入组第一天及治疗两个和四个疗程后。
3、心理评估测试时间16PF测试在入组第一天进行,划消测验在入组第1天、第90天和第180天分别进行。
4、临床疗效观察指标包括House Brackmann分级量表、临床的症状体征、Nottingham面神经分级量表和FDIP评分量表。
结果：
1、治疗贝尔麻痹疗效针药结合的疗效分析
四个疗程治疗后,二元人格因素四种类型的各分组和划消测验的各分组总有效率为100%,各个分组均无无效病例出现说明针药结合治疗贝尔麻痹疗效好,且神经心理因素对针药结合治疗贝尔麻痹的疗效无明显影响。
2、House Brackmann分级量表的疗效分析
治疗前二元人格因素的同一类型的低中高分组的组间House Brackmann分级无显著差异及划消测验低中高分组的组间House Brackmann分级无显著差异,治疗两个及四个疗程后上述组间均无显著差异,说明神经心理因素对针药结合治疗贝尔麻痹的疗效无明显影响。
3、Nottingham面神经分级量表疗效分析
治疗前二元人格因素的同一类型的低中高分组的组间Nottingham面神经分级无显著差异及划消测验低中高分组的组间Nottingham面神经分级无显著差异,治疗两个及四个疗程后上述组间均无显著差异,说明神经心理因素对针药结合治疗贝尔麻痹的疗效无明显影响。
4、面部残疾指数躯体功能(FDIP)疗效分析
治疗前二元人格因素的同一类型的低中高分组的组间FDIP评分无显著差异及划消测验低中高分组的组间FDIP评分无显著差异,治疗两个及四个疗程后上述组间均无显著差异,说明神经心理因素对针药结合治疗贝尔麻痹的疗效无明显影响。
结论：
该次临床观察证明,针药结合治疗贝尔麻痹在改善患者的局部临床症状、促进面神经机能恢复及改善躯体功能方面均有显著疗效。通过对各个观察组的治疗结果统计后的比较,证实神经心理因素对针药结合治疗贝尔麻痹的临床疗效无明显影响。
Objective:
This clinical observation is a part of the topic "Acupuncture treatment of Bell's Palsy in a gas and neuron-psychological factors on the effects of acupuncture, multi-center randomized controlled trials" which is the sub-topic of the national 973 project "Research on Specificity and Influencing factors of Meridian Effect" (topic number:2006CB504502). Through the treatment of Bell's Palsy patients,the study takes clinical efficacy of the treatment with injection and medicine for Bell's Pslsy as an entry point, in which Cattell personality factor test and cancellation test are used. It observes the neuropsychological factor's influence on clinical efficacy of acupuncture to do preliminary research on meridian effect law.
Methods:
First、clinical data
The clinical research cases are from 50 outpatients and inpatients who received treatment in Hubei Chinese Medicine Hospital from March 2009 to September 2010. The patients are taken Cattell personality factor test and cancellation test under the requirement. Record the score of each scale and take them as metrics of neuropsychological factor.Convert the score of Cattell personality factor test into standards and calculate four subfactor score of personality types (dual personality) corresponding to the calculation formula. Cancellation test calculate the score of working eff icency corresponding to the calculation formula, Divide the patients according to score high in the corresponding low-score,medium-score and high-score group,and carries on the observation. Patients were given the same medicine therapy. Prednisone tablets:30mg po qd*7 days,20mg po qd*4 days, 10g po qd*3 days; Vitamin B1 injection: 0.1, intramuscular injecton*14 days; Mecobalamin injection: 0.5mg, intramuscular injection*14 days; 14 days later,Vitamin B1 tablets,20mg, three times a day; Mecobalamin tablets,0.5mg, tid. Each group was treated with acupuncture in the same acupoint in the first 4 weeks. Second、observation time
Clinical sympotoms and related scale index were observed and recorded on the first day of patients'enrollment and after 2 and 4 courses of treament.
Third、psychological test time
Patients were tested with 16pf on the first day of enrollment and with cancellation on the 1st,90th and 180th day.
Fourth、index observation
Clinical symptoms and signs, House Brackmann grading scale and Nottingham facial never grading scale and physical function index of facial deformity index were observed.
Results:
First、the analysis of the efficacy of treatment with injection and medicine for Bell's Palsy
After 4 courses of treatment, the total efficiency rate of each group was 100% with no ineffective case. It indicates it's effective to treat Bell's Palsy with injection and medicine and the efficacy is not influenced by neuropsychological factor.
Second, the analysis of the efficacy of House Brackmann graging scale
Each group was compared before the treament and after 2 and 4 courses.By comparison, there is no marked difference in each group. So there is no marked difference within groups and it shows it's effective to treat Bell's Palsy with injection and medicine and the efficacy is not influenced by neuropsychological factor.
Third、the analysis of the efficacy of facial nerve grading scale
Each group was compared before the treament and after 2 and 4 courses.By comparison, there is no marked difference in each group. So there is no marked difference within groups and it shows it's effective to treat Bell's Palsy with injection and medicine and the efficacy is not influenced by neuropsychological factor.
Fourth、the analysis of facial deformity index and physical function efficacy.
Each group was compared before the treament and after 2 and 4 courses. By comparison, there is no marked difference in each group. So there is no marked difference within groups and it shows it's effective to treat Bell's Palsy with injection and medicine and the efficacy is not influenced by neuropsychological factor.
Conclusion:
This clinical observation proves the treatment of injection and medicine for Bell's Palsy has notable efficacy in improving local syptoms, promoting the recovery of facial nerve function and bettering patients'physical function. Through the comparison of the statistical treatment results of each group, it confirms the neuropsychological factor does not affect the clinical effect of the treatment with injection and medicine for Bell's Palsy.
本临床观察是国家重点基础研究发展计划“经穴效应特异性及影响因素研究”(课题编号：2006CB504502)之子课题“针刺治疗贝尔麻痹中得气和神经心理因素对针刺效应影响的多中心随机对照试验”的一部分。本研究通过治疗50例贝尔麻痹患者,以针药结合治疗贝尔麻痹的临床疗效为切入点,以卡特尔人格因素测验和划消测验为方法,观察研究神经心理因素对临床针刺疗效的影响,以初步探讨经穴效应规律。
方法：
1、临床资料该临床观察研究病例是从2009年3月至2010年9月湖北省中医院的门诊和住院患者中筛选出的50例患者,患者按要求进行16PF和划消测验,记录的各个量表的分数,以这些分数作为神经心理因素的度量值。将16PF测验得分转化为标准分后按对应的公式计算出四种可以形容人格类型的次级因素(称二元人格特征)的得分,划消测验根据对应的计算公式计算出工作效率得分,将患者按照得分高低分为对应的低分组、中分组和高分组进行观察分析。患者均给以相同的药物治疗,强的松片：30mg qd×7天,20mg qd×4天,10mg qd×3天；维生素B1针：0.1,肌注,×14天；甲钻胺(弥可保)针：0.5mg,肌注,×14天；14天后,口服维生素B1片：20mg, tid;甲钴铵(弥可保)片：0.5mg, tid。各组在发病后至入选第4周均采用相同穴位进行针刺治疗。
2、治疗效果观察时间观察记录临床症状与入组第一天及治疗四个疗程后及相关量表指标于入组第一天及治疗两个和四个疗程后。
3、心理评估测试时间16PF测试在入组第一天进行,划消测验在入组第1天、第90天和第180天分别进行。
4、临床疗效观察指标包括House Brackmann分级量表、临床的症状体征、Nottingham面神经分级量表和FDIP评分量表。
结果：
1、治疗贝尔麻痹疗效针药结合的疗效分析
四个疗程治疗后,二元人格因素四种类型的各分组和划消测验的各分组总有效率为100%,各个分组均无无效病例出现说明针药结合治疗贝尔麻痹疗效好,且神经心理因素对针药结合治疗贝尔麻痹的疗效无明显影响。
2、House Brackmann分级量表的疗效分析
治疗前二元人格因素的同一类型的低中高分组的组间House Brackmann分级无显著差异及划消测验低中高分组的组间House Brackmann分级无显著差异,治疗两个及四个疗程后上述组间均无显著差异,说明神经心理因素对针药结合治疗贝尔麻痹的疗效无明显影响。
3、Nottingham面神经分级量表疗效分析
治疗前二元人格因素的同一类型的低中高分组的组间Nottingham面神经分级无显著差异及划消测验低中高分组的组间Nottingham面神经分级无显著差异,治疗两个及四个疗程后上述组间均无显著差异,说明神经心理因素对针药结合治疗贝尔麻痹的疗效无明显影响。
4、面部残疾指数躯体功能(FDIP)疗效分析
治疗前二元人格因素的同一类型的低中高分组的组间FDIP评分无显著差异及划消测验低中高分组的组间FDIP评分无显著差异,治疗两个及四个疗程后上述组间均无显著差异,说明神经心理因素对针药结合治疗贝尔麻痹的疗效无明显影响。
结论：
该次临床观察证明,针药结合治疗贝尔麻痹在改善患者的局部临床症状、促进面神经机能恢复及改善躯体功能方面均有显著疗效。通过对各个观察组的治疗结果统计后的比较,证实神经心理因素对针药结合治疗贝尔麻痹的临床疗效无明显影响。
Objective:
This clinical observation is a part of the topic "Acupuncture treatment of Bell's Palsy in a gas and neuron-psychological factors on the effects of acupuncture, multi-center randomized controlled trials" which is the sub-topic of the national 973 project "Research on Specificity and Influencing factors of Meridian Effect" (topic number:2006CB504502). Through the treatment of Bell's Palsy patients,the study takes clinical efficacy of the treatment with injection and medicine for Bell's Pslsy as an entry point, in which Cattell personality factor test and cancellation test are used. It observes the neuropsychological factor's influence on clinical efficacy of acupuncture to do preliminary research on meridian effect law.
Methods:
First、clinical data
The clinical research cases are from 50 outpatients and inpatients who received treatment in Hubei Chinese Medicine Hospital from March 2009 to September 2010. The patients are taken Cattell personality factor test and cancellation test under the requirement. Record the score of each scale and take them as metrics of neuropsychological factor.Convert the score of Cattell personality factor test into standards and calculate four subfactor score of personality types (dual personality) corresponding to the calculation formula. Cancellation test calculate the score of working eff icency corresponding to the calculation formula, Divide the patients according to score high in the corresponding low-score,medium-score and high-score group,and carries on the observation. Patients were given the same medicine therapy. Prednisone tablets:30mg po qd*7 days,20mg po qd*4 days, 10g po qd*3 days; Vitamin B1 injection: 0.1, intramuscular injecton*14 days; Mecobalamin injection: 0.5mg, intramuscular injection*14 days; 14 days later,Vitamin B1 tablets,20mg, three times a day; Mecobalamin tablets,0.5mg, tid. Each group was treated with acupuncture in the same acupoint in the first 4 weeks. Second、observation time
Clinical sympotoms and related scale index were observed and recorded on the first day of patients'enrollment and after 2 and 4 courses of treament.
Third、psychological test time
Patients were tested with 16pf on the first day of enrollment and with cancellation on the 1st,90th and 180th day.
Fourth、index observation
Clinical symptoms and signs, House Brackmann grading scale and Nottingham facial never grading scale and physical function index of facial deformity index were observed.
Results:
First、the analysis of the efficacy of treatment with injection and medicine for Bell's Palsy
After 4 courses of treatment, the total efficiency rate of each group was 100% with no ineffective case. It indicates it's effective to treat Bell's Palsy with injection and medicine and the efficacy is not influenced by neuropsychological factor.
Second, the analysis of the efficacy of House Brackmann graging scale
Each group was compared before the treament and after 2 and 4 courses.By comparison, there is no marked difference in each group. So there is no marked difference within groups and it shows it's effective to treat Bell's Palsy with injection and medicine and the efficacy is not influenced by neuropsychological factor.
Third、the analysis of the efficacy of facial nerve grading scale
Each group was compared before the treament and after 2 and 4 courses.By comparison, there is no marked difference in each group. So there is no marked difference within groups and it shows it's effective to treat Bell's Palsy with injection and medicine and the efficacy is not influenced by neuropsychological factor.
Fourth、the analysis of facial deformity index and physical function efficacy.
Each group was compared before the treament and after 2 and 4 courses. By comparison, there is no marked difference in each group. So there is no marked difference within groups and it shows it's effective to treat Bell's Palsy with injection and medicine and the efficacy is not influenced by neuropsychological factor.
Conclusion:
This clinical observation proves the treatment of injection and medicine for Bell's Palsy has notable efficacy in improving local syptoms, promoting the recovery of facial nerve function and bettering patients'physical function. Through the comparison of the statistical treatment results of each group, it confirms the neuropsychological factor does not affect the clinical effect of the treatment with injection and medicine for Bell's Palsy.
引文
[1]黄银兰；刁灿阳；严苏纯；孟玉凤；经穴效应关键影响因素现代研究进展；辽宁中医药大学学报2007年03期
[2]孙传新.临床疾病诊断依据治愈好转标准[M].北京：人民军医出版社,1998,198.2
[3]House Jw, Braekmann DE. Facial never grading system[J]. Otolaryngol Head Neek Surg.1985,93:146-147
[4]The faeial disability index:reliability and validity of a disability assessment Instrument for disordersof the facial neuromuseular system[J].Physieal Therapy,1996, (5):1228-1297
[5]王燕描,李志明.Bell氏麻痹研究进展. 中华耳鼻喉杂志[J],1990,25(3)：181-184
[6]杨博民.心理实验纲要.北京：北京大学出版社,1989,147-149,335-337
[7]戴忠恒,祝蓓里.修订卡氏十六种人格因素量表手册[M],上海：华东师范大学,1988：39
[8]秦喆.大学生感恩意识与人格特征、父母养育方式的关系研究[D].扬州：扬州大学,2009.
[9]李霞.大学生网络成瘾与人格特质关系的研究[D].沈阳：东北师范大学,2008.
[10]贵州省高校学生人格因素与创新精神调查研究[D].贵阳：贵州师范大学,2006.
[11]李惠云,乔晓熔.初入学儿童基本情况及其与父母受教育程度相关的研究[J].教育科学研究,2005,7.
[12]刘爱书等.行为问题儿童精神运动功能配对研究[J].中国心理卫生杂志.2003,17(4)：247-235.
[13]周云飞等,强迫思维型、强迫行为型和混合型强迫症患者认知功能的差异[J].中国临床康复,2006,10(2).
[14]江滨等.睡眠惯性对午睡后认知功能的影响[J].中国临床康复,2004,8(1).
[15]张玉红.面瘫的针灸治疗方法概况.现代中西医结合杂志[J],2008,17(10)：1614-1615
[16]黄昕军.留针时间与疗效探讨[J].湖南中医学院学报,1993：1 3(4)：51
[17]王新玲、针药治疗糖尿病伴发面瘫的临床观察,北京中医药大学硕士论文
[18]岳远更、久留针及分期不同针刺治疗面神经炎的临床观察,黑龙江中医药大学硕士论文
[19]张晓洁.新疆某医科独立学院大学生非智力因素发展水平及其对学生学习成绩的影响[D].乌鲁木齐：新疆医科大学,2008.
[20]邹琴.不同情境下人格与大学生顺从行为间关系的研究[D]南昌：江西师范大学,2007.
[21]葛盛秋.飞行疲劳对不同年龄民航飞行人员视觉融合的影响[J].中国航空航天医学杂志,2005,16(3).
[22]张莹等.高校学生抑郁状态下认知功能的比较研究[J].中国神经精神疾病杂志,2007,33(7).
[23]郑开梅.抑郁症中医证候特征及相关社会心理因素的临床流行病学调查.天津中医学院博士论文
[1]于建春,于涛,韩景献.从基因表达差异分析腧穴和非腧穴针刺效应差异[J].中国针灸,2002,22(11)：749-751.
[2]石学敏.针灸学[M].北京：中国中医药出版社,2002：150.
[3]郭义.实验针灸学[M].北京：中国中医药出版社,2008：189.
[4]陈少宗. 针刺作用四大规律的统一与现代针灸学理论的发展[J].医学与哲学(人文社会医学版),2008,29(11)：67-70.
[5]陈少宗.现代时间针灸学理论与临床应用[M].第一版,黄河出版社(济南),1990：2.
[6]陈少宗.论现代时间针灸学的基本理论[M].第一版,时间医学杂志,1996：25.
[7]伊膝真次.人体的昼夜节律(吴今义译)[M].第一版,重庆科技出版社(重庆),1982：49.
[8]陕西中医学院.现代经络研究文献综述[M].第一版,人民卫生出版社(北京),1980：40.
[9]骆永珍,等.致敏家兔皮试反应强度和血桨皮质酮含量的子午时辰差异[J].云南中医学院学报,1989(2)：5-9.
[10]陈少宗.针刺内关穴对冠心病患者左心功能的改善作用与针刺前心功能状态的相关性研究[J].国际临床针灸杂志,1995(3)：35-39.
[11]陈少宗.不同时间内电针三阴交穴对肾阳虚家兔肾上腺皮质功能的影响[J].美国中医科学,1998(3)：34-39.
[12]周逸平,汪克明,胡玲,等.经脉脏腑相关研究展望[J].安徽中医学院学报,2009,28(5)：1-6.
[13]朱江,马惠芳,付平,等.通过植物神经功能状态的变化看针灸效应[J].中国针灸,2002,22(12)：843-849.
[14]Mark AL, Agaasandian K, Morgan DA, et al. Leptin signaling in the nucleus tractus solitarii increases sympathetic nerve activity to the kidney [J]. Hyperension,2009,53 (2):375-381.
[15]刘里远,潘娟,张慧.针刺信号的立毛线传递及其交感轴突反射机制研究[J].中国中医基础医学杂志,2004,10(2)：50-56.
[16]杨媛,王蒙,尹玲.颈交感神经阻滞对脑血管的影响[J].海南医学院学报,2009 15(6)：684-688.
[17]Firat Y, Kizilay A, Ozturan 0, et al. Experimental otoacoustic emission and auditory brainstem response changes by stellate gangl ion blockage in rat [J]. Am J Otolaryngol,2008,28 (5):339-343.
[18]邢翰,张春红.人迎穴临床研究近况[J].针灸临床杂志,201 0,26(2)：70-73.
[19]汪克明,周逸平,周美启,等.电针经脉对急性心肌缺血家兔心交感神经放电活动的影响[J].针刺研究,2005,30(2)：106-110.
[20]Li Z, Jiao K, Chen M, et al. Effect of magnitopunctureon sympathetic and parasympathetic nerve activities in healthy drivers-assessment by power spectrum analysis of heart rate variability [J]. Eur J Appl Physiol,2003,88 (4/5):404-410.
[21]郭英俊,李英杰,贾和平,等.神经电生理定量测定偏头痛患者自主神经功能及其意义初探[J]. 中国现代医学杂志,2008,18(12)：1740-1746.
[22]李英杰,郭英俊,贾和平,等.颈交感神经节阻滞治疗偏头痛及其对交感神经皮肤反应的影响[J]. 卒中与神经疾病,2008,15(6)：347-350.
[23]盂卓,吕国蔚.足三里一脊髓背角一孤束核的功能联系[J].中国科学,1992,35(9)：393-399.
[24]李江山,严洁,何军锋.针刺内关、足三里等穴对大鼠孤束核神经元放电的影响[J].湖南中医药大学学报,2007,27(3)：55-58.
[2]孙传新.临床疾病诊断依据治愈好转标准[M].北京：人民军医出版社,1998,198.2
[3]House Jw, Braekmann DE. Facial never grading system[J]. Otolaryngol Head Neek Surg.1985,93:146-147
[4]The faeial disability index:reliability and validity of a disability assessment Instrument for disordersof the facial neuromuseular system[J].Physieal Therapy,1996, (5):1228-1297
[5]王燕描,李志明.Bell氏麻痹研究进展. 中华耳鼻喉杂志[J],1990,25(3)：181-184
[6]杨博民.心理实验纲要.北京：北京大学出版社,1989,147-149,335-337
[7]戴忠恒,祝蓓里.修订卡氏十六种人格因素量表手册[M],上海：华东师范大学,1988：39
[8]秦喆.大学生感恩意识与人格特征、父母养育方式的关系研究[D].扬州：扬州大学,2009.
[9]李霞.大学生网络成瘾与人格特质关系的研究[D].沈阳：东北师范大学,2008.
[10]贵州省高校学生人格因素与创新精神调查研究[D].贵阳：贵州师范大学,2006.
[11]李惠云,乔晓熔.初入学儿童基本情况及其与父母受教育程度相关的研究[J].教育科学研究,2005,7.
[12]刘爱书等.行为问题儿童精神运动功能配对研究[J].中国心理卫生杂志.2003,17(4)：247-235.
[13]周云飞等,强迫思维型、强迫行为型和混合型强迫症患者认知功能的差异[J].中国临床康复,2006,10(2).
[14]江滨等.睡眠惯性对午睡后认知功能的影响[J].中国临床康复,2004,8(1).
[15]张玉红.面瘫的针灸治疗方法概况.现代中西医结合杂志[J],2008,17(10)：1614-1615
[16]黄昕军.留针时间与疗效探讨[J].湖南中医学院学报,1993：1 3(4)：51
[17]王新玲、针药治疗糖尿病伴发面瘫的临床观察,北京中医药大学硕士论文
[18]岳远更、久留针及分期不同针刺治疗面神经炎的临床观察,黑龙江中医药大学硕士论文
[19]张晓洁.新疆某医科独立学院大学生非智力因素发展水平及其对学生学习成绩的影响[D].乌鲁木齐：新疆医科大学,2008.
[20]邹琴.不同情境下人格与大学生顺从行为间关系的研究[D]南昌：江西师范大学,2007.
[21]葛盛秋.飞行疲劳对不同年龄民航飞行人员视觉融合的影响[J].中国航空航天医学杂志,2005,16(3).
[22]张莹等.高校学生抑郁状态下认知功能的比较研究[J].中国神经精神疾病杂志,2007,33(7).
[23]郑开梅.抑郁症中医证候特征及相关社会心理因素的临床流行病学调查.天津中医学院博士论文
[1]于建春,于涛,韩景献.从基因表达差异分析腧穴和非腧穴针刺效应差异[J].中国针灸,2002,22(11)：749-751.
[2]石学敏.针灸学[M].北京：中国中医药出版社,2002：150.
[3]郭义.实验针灸学[M].北京：中国中医药出版社,2008：189.
[4]陈少宗. 针刺作用四大规律的统一与现代针灸学理论的发展[J].医学与哲学(人文社会医学版),2008,29(11)：67-70.
[5]陈少宗.现代时间针灸学理论与临床应用[M].第一版,黄河出版社(济南),1990：2.
[6]陈少宗.论现代时间针灸学的基本理论[M].第一版,时间医学杂志,1996：25.
[7]伊膝真次.人体的昼夜节律(吴今义译)[M].第一版,重庆科技出版社(重庆),1982：49.
[8]陕西中医学院.现代经络研究文献综述[M].第一版,人民卫生出版社(北京),1980：40.
[9]骆永珍,等.致敏家兔皮试反应强度和血桨皮质酮含量的子午时辰差异[J].云南中医学院学报,1989(2)：5-9.
[10]陈少宗.针刺内关穴对冠心病患者左心功能的改善作用与针刺前心功能状态的相关性研究[J].国际临床针灸杂志,1995(3)：35-39.
[11]陈少宗.不同时间内电针三阴交穴对肾阳虚家兔肾上腺皮质功能的影响[J].美国中医科学,1998(3)：34-39.
[12]周逸平,汪克明,胡玲,等.经脉脏腑相关研究展望[J].安徽中医学院学报,2009,28(5)：1-6.
[13]朱江,马惠芳,付平,等.通过植物神经功能状态的变化看针灸效应[J].中国针灸,2002,22(12)：843-849.
[14]Mark AL, Agaasandian K, Morgan DA, et al. Leptin signaling in the nucleus tractus solitarii increases sympathetic nerve activity to the kidney [J]. Hyperension,2009,53 (2):375-381.
[15]刘里远,潘娟,张慧.针刺信号的立毛线传递及其交感轴突反射机制研究[J].中国中医基础医学杂志,2004,10(2)：50-56.
[16]杨媛,王蒙,尹玲.颈交感神经阻滞对脑血管的影响[J].海南医学院学报,2009 15(6)：684-688.
[17]Firat Y, Kizilay A, Ozturan 0, et al. Experimental otoacoustic emission and auditory brainstem response changes by stellate gangl ion blockage in rat [J]. Am J Otolaryngol,2008,28 (5):339-343.
[18]邢翰,张春红.人迎穴临床研究近况[J].针灸临床杂志,201 0,26(2)：70-73.
[19]汪克明,周逸平,周美启,等.电针经脉对急性心肌缺血家兔心交感神经放电活动的影响[J].针刺研究,2005,30(2)：106-110.
[20]Li Z, Jiao K, Chen M, et al. Effect of magnitopunctureon sympathetic and parasympathetic nerve activities in healthy drivers-assessment by power spectrum analysis of heart rate variability [J]. Eur J Appl Physiol,2003,88 (4/5):404-410.
[21]郭英俊,李英杰,贾和平,等.神经电生理定量测定偏头痛患者自主神经功能及其意义初探[J]. 中国现代医学杂志,2008,18(12)：1740-1746.
[22]李英杰,郭英俊,贾和平,等.颈交感神经节阻滞治疗偏头痛及其对交感神经皮肤反应的影响[J]. 卒中与神经疾病,2008,15(6)：347-350.
[23]盂卓,吕国蔚.足三里一脊髓背角一孤束核的功能联系[J].中国科学,1992,35(9)：393-399.
[24]李江山,严洁,何军锋.针刺内关、足三里等穴对大鼠孤束核神经元放电的影响[J].湖南中医药大学学报,2007,27(3)：55-58.